• 제목/요약/키워드: Low risk

검색결과 4,363건 처리시간 0.044초

미확정 편평 상피세포와 인체 유두종 바이러스와의 비교 (Comparison of ASCUS and HPV Hybrid Capture II Test Results)

  • 박미순;장병수
    • 한국콘텐츠학회:학술대회논문집
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    • 한국콘텐츠학회 2012년도 춘계 종합학술대회 논문집
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    • pp.175-176
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    • 2012
  • 세포선별검사에서 ASCUS로 진단된 검체 중 F-UP이 진행되지 않은 검체 179건을 대상으로 HPV High risk factor, Low risk factor를 확인하기 위해서 Hybrid Capture II Test를 하였다. 결과 High risk factor 양성 및 Low risk factor 양성은 전체 179 cases 중 25 cases로 나타났으며, 전체 검체 중 약 15%에 해당되었다. 또한 전체 15%의 양성검체 중 High risk factor 양성은 87%에 해당되는 것을 확인하였다. 결론적으로 효과적인 검진 체계를 갖춘 나라에서도 자궁경부암의 예방이 완전히 해결되지 않고 있는 문제점이 있는 여건을 고려해 볼 때 추적 관찰이 용이하지 않은 경우를 대비해 자궁경부암으로 진행될 수 있는 precancerous lesion의 원인 인자인 HPV 존재 유무를 세포선별검사와 HPV Hybrid Capture II Test를 동시에 시행하는 것이 효과적이라고 사료된다.

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API-581에 의한 정량적 위험기반검사에서 취성파괴에 의한 사고발생 가능성 해석 (Analysis of Likelihood of Failure for the Brittle Fracture through Quantitative Risk Based Inspection using API-581)

  • 김태옥;이헌창;장서일
    • 한국가스학회지
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    • 제10권1호
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    • pp.1-6
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    • 2006
  • 압력설비를 안전하고 효율적으로 사용하기 위하여 본 연구에서는 API-581 절차에 의한 위험기반검사에서 취성파괴에 의한 사고발생 가능성을 정량적으로 해석하였다. 그 결과, 낮은 온도/낮은 인성파괴와 뜨임취성에서는 A 충격곡선이고. 낮은 온도와 열처리 전인 상태에서 기술종속계수(TMSF)가 큰 값을 나타내었고, $855^{\circ}F$ 취성에서는 위험도가 무시할 수 있었으나, 시그마상 취성에서는 낮은 온도의 고 시그마인 경우에 TMSF가 큰 값을 나타내어 사고발생 가능성이 매우 높았다.

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위해성 평가 및 관리에 있어서 발암물질의 인체발암능력 평가 (Estimation of Human Carcinogenic Potency (HCP) of Carcinogens in Risk Assessment and Management.)

  • 이병무;김대영;김세기;김근종
    • 한국환경성돌연변이발암원학회지
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    • 제19권1호
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    • pp.39-45
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    • 1999
  • Human Carcinogenic Potency (HCP) can be estimated based on human daily exposure dose to carcinogen (Dh), body weight (Wh), 10% tumorigenic dose (TD10), and slope factor at TD10 (Q10) from 2-yr bioassay data. This approach is more relevant to humans generally exposed to low doses of carcinogens and can reduce more of extrapolation errors from high dose in animal experiments to low dose in humans than HERP (human exposure dose/rodent potency dose) proposed by Ames et al. (Science, 236, 271-280, 1987). TD50 and HERP have been routinely used to compare rodent carcinogenic potency and human carcinogenic potency, but those approaches have had limitations in extrapolation of high dose to low dose in humans. The advantages of HCP are to estimate human exposure dose (Dh) by human monitoring instead of environmental monitoring, to consider slope factor (Q10) which reflects the tendency of curve at low dose, and to use TD10 which represents much lower dose thant TD50 or HERP. HCP will be a useful parameter for the estimation of human carcinogenic potency in risk assessment and management of carcinogens.

제품에 대한 부정적 정보 공개의 단기적 효과에 대한 연구 (The Short-Term Effect of Low-Quality Sellers' Voluntary Information Disclosure)

  • 허승
    • 융합정보논문지
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    • 제11권1호
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    • pp.80-90
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    • 2021
  • 본 논문은 시장에서 저품질의 제품을 판매하는 판매자가 언제, 그리고 어떠한 방식으로 품질에 대한 정보를 공개함으로써 이윤을 증대시킬 수 있을지를 이해하고자 한다. 이를 위해 본 논문은 제품의 품질 및 가격, 고객의 위험 인식 수준, 위험과 관련된 비용, 위험에 대한 민감도 등의 요소를 반영한 새로운 이론 모델 분석을 통해 저품질의 제품을 판매하는 판매자가 품질에 대한 부정적인 정보를 자발적으로 공개하여도 고객이 인식하는 위험 수준을 충분히 감소시킬 수만 있다면 단기간에 수요를 증대시킬 수 있음을 보여준다. 또한 본 이론 모델은 이러한 정보 공개가 고객의 위험 수준을 어떻게 조정하느냐에 따라 시장 전체 수요와 경쟁 제품의 수요까지도 증대시킬 수 있다는 점을 보여준다. 본 논문의 연구결과는 제품의 부정적 요소에 대한 정보를 관리하는 마케팅 실무자 뿐 아니라 시장에서의 정보 불균형으로 인해 생기는 여러 문제점들을 해결하고자 하는 정책 담당자에게도 유의미한 시사점을 제공해 줄 것으로 기대된다.

Tobacco Use, Beliefs and Risk Awareness in University Students from 24 Low, Middle and Emerging Economy Countries

  • Peltzer, Karl;Pengpid, Supa
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권22호
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    • pp.10033-10038
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    • 2014
  • The aim of this study was to determine the prevalence of tobacco use, beliefs and risk awareness and psychosocial correlates of tobacco use among university students in 24 low, middle and emerging economy countries. Using anonymous questionnaires, data were collected from 16953 undergraduate university students (mean age 20.9, SD=2.9) from 25 universities in 24 countries across Asia, Africa and the Americas. Results indicate that overall 13.3% of the university students were current tobacco users, 22.4% for men and 6.6% for women, ranging from 3.8% in Singapore to 32.5% in Cameroon. The risk awareness of the smoking lung cancer link was 83.6%, while the risk awareness of the smoking heart disease link was 46.5%. Multivariate logistic regression found that older age, male gender, having a wealthy family background, living in a low income country, residing off campus on their own, poor beliefs in the importance not to smoke, awareness of the smoking heart disease link, hit by a sexual partner, depressive symptoms, and substance use (binge drinking and illicit drug use) were associated with current tobacco use.

우리나라 30~64세 성인의 수면시간과 고혈압 관련 요인 (Sleep Duration and the Related Factors of Hypertension among Korean Middle-aged Adults)

  • 박은옥
    • 성인간호학회지
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    • 제26권3호
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    • pp.372-381
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    • 2014
  • Purpose: This study investigated the prevalence of hypertension, explored sleep duration, and examined the related factors to hypertension in Korean middle-aged adults. Methods: Using raw data from the Korean National Health and Nutritional Examination Survey (KNHANES) conducted from 2008 to 2010, a secondary analysis was performed with data from 13,230 adults aged 30~64 years. ${\chi}^2$-test and multiple logistic regressions was used for the data analysis. Results: The prevalence of hypertension among Korean middle-aged adults was 21.8% and 40.3% among participants reported that their average sleep duration was below six hours a night. Risk factors for hypertension include: female (the odds ratio (OR) 1.66 for male), 50~64 years age group (OR 3.66 for 30~49 years age group), education level of elementary school (OR 1.84 for university level), low household income (OR 1.27 for upper), obesity (OR 2.41), high risk drinking (OR 1.64), and sleep duration${\leq}6$ hrs (OR 1.16 for 8 hrs of sleep). Conclusion: High risk population of hypertension could be male, aged, low education, and low income. Obesity, high risk drinking, and short sleep duration should be considered as risk factors for hypertension. Interventions for obesity management, adequate alcohol drinking and sleep duration could be considered for preventing hypertension.

작업조건이 출산결과에 미치는 영향: 전향적 코호트연구 (Maternal Working Conditions on Adverse Pregnancy Outcomes: A Prospective Cohort Study)

  • 김지용;정진주;고경심;조정진
    • Journal of Preventive Medicine and Public Health
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    • 제35권3호
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    • pp.197-204
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    • 2002
  • Objectives : To evaluate the association between working conditions and adverse pregnancy outcomes in Korea. Methods : We obtained data on health history, lifestyle, housework and Working conditions, such as shift work, hours standing, working time, job demand, lifting at work and at home, between August and September 2000, from self-reported questionnaires. A group of 344, occupationally active, pregnant women from 51 industries were studied. Of the women studied, 328 women were further interviewed by telephone between November 2000 and September 2001. Result : Compared with daytime work, shift work increased the risk for preform birth (an adjusted risk ratio of 2.74, 95% CI=1.02-2.62) and low birth weight (an adjusted risk ratio of 2.74,95% CI=1.02-2.02). A significantly increased risk was found for prolonged standing, with an adjusted risk ratio of preform births of 6.80 (95% CI=2.01-23.0). There were no significant differences in the incidence of spontaneous abortion between the occupational working conditions, with the enception of a previous history of spontaneous abortion. Conclusion : These findings suggest that maternal working conditions, such as shift work and prolonged standing, contribute significantly to preterm birth and low birth weight.

1,500MW대형원전 정지/저출력 안전성향상을 위한 설계개선안 및 민감도 분석 (Risk and Sensitivity Analysis during the Low Power and Shutdown Operation of the 1,500MW Advanced Power Reactor)

  • 문호림;한덕성;김재갑;이상원;임학규
    • 한국압력기기공학회 논문집
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    • 제15권1호
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    • pp.33-39
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    • 2019
  • An 1,500MW advanced power reactor required the standard design approval by a Korean regulatory body in 2014. The reactor has been designed to have a 4-train independent safety concept and a passive auxiliary feedwater system (PAFS). The full power risk or core damage frequency (CDF) of 1,500MW advanced power reactor has been reduced more than that of APR1400. However, the risk during the low power and shutdown (LPSD) operation should be reduced because CDF of LPSD is about 4.7 times higher than that of internal full power. The purpose of paper is to analysis design alternatives to reduce risk during the LPSD. This paper suggests design alternatives to reduce risk and presents sensitivity analysis results.

CDU 내 탈황공정의 내부부식 된 파이프라인을 대상으로 한 RBI기법을 이용한 위험성 평가 (Risk Assessment Using RBI for Internal Corroded Pipelines in CDU Desulfurization Process)

  • 임동휘;정태준;이인동;정인희;고재욱
    • 한국가스학회지
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    • 제23권3호
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    • pp.33-39
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    • 2019
  • 2010년대에 들어서 노후화된 공정으로 인하여 많은 공장들의 안전이 보장되지 않은 채로 가동되고 있다. 공정 및 설비의 노후화 문제를 근본적으로 해결하기는 어렵지만, 사전에 위험성 평가로 위험을 예방할 수있다. 본 연구는 CDU(Crude Distillation Unit)의 탈황 장비에 있는 배관에서 황으로 인한 부식을 타겟으로 지정하였고, API RP 581를 참고한 RBI(Risk Based Inspection)기법으로 위험성 평가를 실시하였다. RBI 기법은 Frequency와 Consequence의 조합으로 Risk를 표현하고, 이들을 바탕으로 Risk Matrix를 만든다. 본 연구는 배관의 Hole Size를 Small과 Medium으로, Frequency의 감도는 'Low'로 선택하여 진행하였다. 기준을 통해 만들어진 Risk Matrix를 참고하여 배관에서 황으로 인한 부식의 사고 위험성을 평가하고 향후 사고 방지 계획을 세울 수 있다. 또한 이와 비슷한 방법으로 노후화에 대한 예방을 한다면 보이지 않는 크고 작은 사고들도 예방 할 수 있다.

Quantitative microbial risk assessment indicates very low risk for Vibrio parahaemolyticus foodborne illness from Jeotgal in South Korea

  • Choi, Yukyung;Kang, Joohyun;Lee, Yewon;Seo, Yeongeun;Kim, Sejeong;Ha, Jimyeong;Oh, Hyemin;Kim, Yujin;Park, Eunyoung;Lee, Heeyoung;Lee, Soomin;Rhee, Min Suk;Yoon, Yohan
    • Fisheries and Aquatic Sciences
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    • 제25권9호
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    • pp.463-472
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    • 2022
  • In this study, a microbial risk assessment was performed for the bacteria Vibrio parahaemolyticus, which causes a foodborne illness following the consumption of Jeotgal, a fermented seafood in South Korea. The assessment comprised of six stages: product, market, home, consumption, dose-response, and risk. The initial contamination level (IC) was calculated based on the prevalence of V. parahaemolyticus in 90 Jeotgal samples. The kinetic behavior of V. parahaemolyticus was described using predictive models. The data on transportation conditions from manufacturer to market and home were collected through personal communication and from previous studies. Data for the Jeotgal consumption status were obtained, and an appropriate probability distribution was established. The simulation models responding to the scenario were analyzed using the @RISK program. The IC of V. parahaemolyticus was estimated using beta distribution [Beta (1, 91)]. The cell counts during transportation were estimated using Weibull and polynomial models [δ = 1 / (0.0718 - 0.0097 × T + 0.0005 × T2)], while the probability distributions for time and temperature were estimated using Pert, Weibull, Uniform, and LogLogistic distributions. Daily average consumption amounts were assessed using the Pareto distribution [0.60284,1.32,Risk Truncate(0,155)]. The results indicated that the risk of V. parahaemolyticus infection through Jeotgal consumption is low in South Korea.