• Earthquakes and Structures
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• v.5 no.1
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• pp.23-48
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• 2013

In this study, the effect of flexibility of superstructures and nonlinear characteristics of LRB (Lead Rubber Bearing) isolator on inelastic response of base isolated structures is investigated. To demonstrate the intensity of damage in superstructures, demand response modification factor without the consideration of damping reduction factor, demand RI, is used and the N2 method is applied to compute this factor. To evaluate the influence of superstructure flexibility on inelastic response of base isolated structures, different steel intermediate moment resisting frames with different heights have been investigated. In lead rubber bearing, the rubber provides flexibility and the lead is the source of damping; variations of aforementioned characteristics are also investigated on inelastic response of superstructures. It is observed that an increase in height of superstructure leads to higher value of demand RI till 4-story frame but afterward this factor remains constant; in other words, an increase in height until 4-story frame causes more damage in the superstructure but after that superstructure's damage is equal to the 4-story frame's. The results demonstrate that the low value of second stiffness (rubber stiffness in LRBs) tends to show a significant decrease in demand RI. Increase in value of characteristic strength (yield strength of the lead in LRBs) leads to decrease in the demand RI.

• The Journal of the Korean Society for Microbiology
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• v.6 no.1
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• pp.29-40
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• 1971

Various kinds of antibiotics are generally believed to have inhibitory effects on the antibody response. However, as polymyxin B which belongs to the cyclic polypeptide group of antibiotic was found to have some enhancing effects on the antibody response of rabbits to enterobacterial common antigen(CA) under specified conditions, experiments were carried out on this problem with the following results. 1. When mixture of polymyxin B and CA derived from Salmonella typhimurium(STM) was treated 30 minutes at $37^{\circ}C$ and injected three times into rabbits by intravenous route, the antibody response to CA was weaker than rabbits injected CA only. 2. Mixture of polymyxin B and CA showed a marked antibody production when injected into rabbits primed with small amounts of heat-extracted antigen of STM, while the injection of CA alone showed low titers of response. 3. Mixture of polymyxin B and heat-extracted CA-containing antigen of Escherichia coli 014 also showed a increased antibody production than CA alone in rabbits primed with antigen of STM. 4. The effect of polymyxin B appeared in different ways. This antibiotic did not enhance the CA antibody response in rabbits primed with small amounts of E. coli 0111 and 055, but enhance in rabbits primed with Shigella flexneri. 5. No enhancing effect on the antibody response was observed by polymyxin B in rabbits primed with CA. 6. No enhancing effect on the antibody response was also noted in rabbits primed with STM antigen in case polymyxin B and CA were administered simultaneously but in veins of different places. 7. Bacitracin did not enhance the CA antibody response in primed rabbits with STM antigen, but neomycin slightly enhance the response. 8. Lipopolysaccharide showed no priming effect on the CA antibody response, and no enhancement of the CA antibody response in rabbits printed with STM. 9. The priming effect of STM antigen against CA antibody response was very weak as compared with the effect of CA derived from STM antigen.

• Journal of Life Science
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• v.16 no.4
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• pp.618-625
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• 2006

Patterns of induced daily torpor were measured in the striped field mouse, Apodemus agrarius, in response to low temperature, food deprivation and various photoperiods using implanted data loggers. A total of 8 of 21 females entered daily torpor in response to low outside ambient temperature (Ta) during winter and spring, constant low Ta $(4^{\circ}C)$ or food deprivation $(23^{\circ}C)$ during summer, but 2 of 23 males did only in response to low outside Ta during winter. This fact indicates that torpor is an adaptive hypothermia to unpredictable environment in both some males and females, as well as that torpor was inhibited in males in the reproductive season as in other mammals, which is regarded as a strategy not to reduce the chance of copulation. As for females, however, torpor was employed in response to unpredictable environment even in the reproductive season, suggesting that alternative strategies other than keeping the chance of copulation maybe hired by females to keep the population. Torpor bout generally began at $6{\sim}12$ AM, but the decrease of body temperature $(T_b)$ began mainly at $4{\sim}6$ AM at any conditions, the time when Ta is lowest. This strategy might be also adopted for reducing heat loss to unpredictable environment. Minimum $T_b$ of both males and females during torpor did not fall below $16.5^{\circ}C$. Photoperiod had no influence on the incidence and timing of daily torpor in either males and females. The similar timing of torpor bout in response to the 3 different photoperiods (24D, 16L:8D or 8L:16D) under the constant temperatures $(4^{\circ}C\;or\;23{\pm}2^{\circ}C)$ suggests that entering time of torpor might be controlled by the circadian rhythm of the mice rather than by the photoperiod.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.10
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• pp.5168-5181
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• 2017

The popularity of augmented reality (AR) applications and games are in high demand. Currently, the best common platform to implement AR services is on a smartphone, as online games, navigators, personal assistants, travel guides are among the most popular applications of smartphones. However, the power consumption of an AR application is extremely high, and therefore, highly adaptable and dynamic low power control schemes must be used. Dynamic voltage and frequency scaling (DVFS) schemes are widely used in smartphones to minimize the energy consumption by controlling the device's operational frequency and voltage. DVFS schemes can sometimes lead to longer response times, which can result in a significant problem for AR applications. In this paper, an AR response time monitor is used to observe the time interval between the AR image input and device's reaction time, in order to enable improved operational frequency and AR application process priority control. Based on the proposed response time monitor and the characteristics of the Linux kernel's completely fair scheduler (CFS) (which is the default scheduler of Android based smartphones), a response time step control (RSC) scheme is proposed which adaptively adjusts the CPU frequency and interactive application's priority. The experimental results show that RSC can reduce the energy consumption up to 10.41% compared to the ondemand governor while reliably satisfying the response time performance limit of interactive applications on a smartphone.

• The Transactions of the Korea Information Processing Society
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• v.5 no.9
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• pp.2378-2387
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• 1998

This thesis proposes a design algorithm of an efficient space response compactor for Built-In Self-Testing of VLSI circuits. The proposed design algorithm of space compactors can be applied independently from the structure of Circuit Cnder Test. There are high hardware overhead cost in conventional space response compactors and the fault coverage is reduced by aliasing which maps faulty circuit's response to fault-free one. However, the proposed method designs space response compactors with reduced hardware overheads and does not reduce the fault coverage comparing to conventional method. Also, the proposed method can be extended to general N -input logic gate and design the most efficient space response L'Ompactors according to the characteristies of output sequence from CUT. The prolxlsed design algorithm is implemented by C language on a SUN SPARC Workstation, and some experiment results of the simulation applied to ISCAS'85 benchmark circuits with pseudo random patterns generated bv LFSR( Linear Feedback Shift Register) show the efficiency and validity of the proposed design algorithm.

• Earthquakes and Structures
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• v.5 no.5
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• pp.499-526
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• 2013

Seismic isolation is an effective method for the protection of buildings and their contents during strong earthquakes. This research work aims to assess the appropriateness of the linear and nonlinear models that can be used in the analysis of typical low-rise base isolated steel buildings, taking into account the inherent nonlinearities of the isolation system as well as the potential nonlinearities of the superstructure in case of strong ground motions. The accuracy of the linearization of the isolator properties according to Eurocode 8 is evaluated comparatively with the corresponding response that can be obtained through the nonlinear hysteretic Bouc-Wen constitutive model. The suitability of the linearized model in the determination of the size of the required seismic gap is assessed, under various earthquake intensities, considering relevant methods that are provided by building codes. Furthermore, the validity of the common assumption of elastic behavior for the superstructure is explored and the alteration of the structural response due to the inelastic deformations of the superstructure as a consequence of potential collision to the restraining moat wall is studied. The usage of a nonlinear model for the isolation system is found to be necessary in order to achieve a sufficiently accurate assessment of the structural response and a reliable estimation of the required width of the provided seismic gap. Moreover, the simulations reveal that the superstructure's inelasticity should be taken into account, especially if the response of the structure under high magnitude earthquakes is investigated. The consideration of the inelasticity of the superstructure is also recommended in studies of structural collision of seismically isolated structures to the surrounding moat wall, since it affects the response.

• Quality Improvement in Health Care
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• v.22 no.2
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• pp.75-90
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• 2016

Objectives: This study measures the level of cognition of employee's patient safety culture and evaluates the current level through comparing the results to external levels. Ultimately it is performed to construct a strategic improvement plan through the basic database for patient's safety culture. Methods: A questionnaire survey of self reporting type was carried out using structured questionnaire of the patient's safety culture for employees currently employed in a hospital. Total responders was 1,129 and a response rate was 54.6%. The survey results were calculated with a percent positive response, and the current level was evaluated by comparing with the survey results of a hospital (2009 and 2014) and the survey result of The Agency for Healthcare Research and Quality(2014). Results: Sub-dimension of high percent positive response for each area were 'teamwork within hospital units' (80%), 'feedback & communication about error' (73%) and 'supervisor/manager expectations & actions promoting safety' (67%). Meanwhile, 'teamwork across hospital units' (31%), 'hospital management support for patient safety' (29%), 'staffing' (27%) and 'non-punitive response to error' (17%) were relatively low percent positive response. Compared to the survey results of AHRQ (2014) for each area, 'teamwork within hospital units' (80%), 'feedback & communication about error' (73%), 'frequency of event reporting' (66%) were at the top 50% percentile level and the remaining sub-dimensions showed a very low level in the lower 10% percentile area. Conclusion: In order to establish a system for patient safety culture within the hospital and evaluate the effect on this, it is necessary to periodically evaluate the patient's safety culture and establish regulations on hospital safety culture to comply with this.

• Wind and Structures
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• v.9 no.1
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• pp.1-22
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• 2006

The response characteristics and suppression of flow-induced vibrations of rectangular prisms with various width-to-depth ratios were experimentally investigated. The prisms were rigid and elastically mounted at both ends to enable constrained torsional vibrations only. The present study focused on torsional vibrations, one of the three types of flow-induced vibrations generated in a rectangular prism. First, the response characteristics of torsional vibrations generated in rectangular prisms were investigated by free-vibration tests. It was found that the response characteristics of torsional vibrations generated in rectangular prisms could be classified into six patterns depending on the width-to-depth ratio. Next, the response characteristics of torsional vibrations observed in the free-vibration tests were reproduced by forced-vibration tests, and the mechanisms by which the three types of flow-induced vibrations, low-speed torsional flutter, vortex excitation and high-speed torsional flutter, are generated in the rectangular prisms were elucidated on the basis of characteristics of fluid forces and visualized flow patterns. Experiments were also carried out to establish an effective method for suppressing flow-induced vibrations generated in the rectangular prisms, and it was found that low-speed torsional flutter and high-speed torsional flutter could be suppressed by placing a small normal plate upstream of the prism, which results in suppression of the alternating rolling-up of the shear layers separating from the leading edges of the prism. It was also found that vortex excitation could be suppressed by placing a splitter plate downstream of the prism, which results in suppression of the generation of wake vortices.

• Clinical and Experimental Vaccine Research
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• v.12 no.1
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• pp.13-24
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• 2023

This systematic and meta-analysis aims to evaluate humoral and cellular responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine among kidney transplant recipients (KTRs). We conducted a systematic literature search across databases to evaluate seroconversion and cellular response rates in KTRs receiving SARS-CoV-2 vaccines. We extracted studies that assessed seroconversion rates described as the presence of antibody de novo positivity in KTRs following SARS-CoV-2 vaccination published up to January 23rd, 2022. We also performed meta-regression based on immunosuppression therapy used. A total of 44 studies involving 5,892 KTRs were included in this meta-analysis. The overall seroconversion rate following complete dose of vaccines was 39.2% (95% confidence interval [CI], 33.3%-45.3%) and cellular response rate was 41.6% (95% CI, 30.0%-53.6%). Meta-regression revealed that low antibody response rate was significantly associated with the high prevalence of mycophenolate mofetil/mycophenolic acid (p=0.04), belatacept (p=0.02), and antiCD25 induction therapy uses (p=0.04). Conversely, tacrolimus use was associated with higher antibody response (p=0.01). This meta-analysis suggests that postvaccination seroconversion and cellular response rates in KTRs are still low. And seroconversion rate was correlated with the type of immunosuppressive agent and induction therapy used. Additional doses of the SARS-CoV-2 vaccine for this population using a different type of vaccine are considered.

• 도로교통
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• s.76
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• pp.2-7
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• 1999

Seismic design in low to moderate seismic regions has to be based on the characteristics of seismic risk, ground motion and structural response in that region. The characteristics of seismic hazard in low to moderate seismic regions are reviewed briefly. The recent findings on the dynamic behavior subjected to the moderate intensity level of ground motion are summarized. The seismic design considerations in Eastern America, China, Australia, Thailand and Hong Kong will be introduced. The effort to adopt the limited ductility design in low to moderate seismicity regions will be reported. Finally research works that are required for the implementation of the limited design concept will be proposed.