• Title/Summary/Keyword: Low response

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Electro-optical Properties of Polymer-Stabilized Nematic Pi Cells

  • Huang, Chi-Yen;Fung, Ri-Xin;Lin, Ying-Ging
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.954-957
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    • 2007
  • We analyzed conditions for fabricating zero-bias polymer-stabilized liquid crystal (PSLC) pi cells. A high curing voltage and a very low curing intensity are effective in fabricating the cell with a high bright state, a low dark state and therefore a steep T-V curve. However, the response time of the cell is slow. Finally, a dual-frequency PSLC pi cell with fast response time is developed. The obtained result reveals that the dual-frequency PSLC pi cell has a fast response of under 1ms.

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Study on Continuous Nearest Neighbor Query on Trajectory of Moving Objects (이동객체의 궤적에 대한 연속 최근접 질의에 관한 연구)

  • Chung, Ji-Moon
    • Journal of Digital Convergence
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    • v.3 no.1
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    • pp.149-163
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    • 2005
  • Researches for NN(nearest neighbor) query which is often used in LBS system, have been worked. However. Conventional NN query processing techniques are usually meaningless in moving object management system for LBS since their results may be invalidated as soon as the query and data objects move. To solve these problems, in this paper we propose a new nearest neighbor query processing technique, called CTNN, which is possible to meet continuous trajectory nearest neighbor query processing. The proposed technique consists of Approximate CTNN technique which has quick response time, and Exact CTNN technique which makes it possible to search accurately nearest neighbor objects. Experimental results using GSTD datasets shows that the Exact CTNN technique has high accuracy, but has a little low performance for response time. They also shows that the Approximate CTNN technique has low accuracy comparing with the Exact CTNN, but has high response time.

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Frequency Response of the electrode for Indirect-contact ECG (간접접촉 심전도 측정용 전극의 주파수 특성)

  • Lim, Yong-Gyu
    • Journal of Biomedical Engineering Research
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    • v.29 no.3
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    • pp.249-253
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    • 2008
  • The indirect-contact ECG (IDC-ECG) was introduced by a prior study for daily non-intrusive measurements. To improve the signal quality and to extend the application area of IDC-ECG, close study of the frequency characteristics of the IDC-ECG is necessary. In this study, the frequency response of the active electrode for several sample clothes was measured under conditions of actual IDC-ECG measurement with human body. Higher gain in low frequency range than expected by prior study was observed. In addition to it, wide variation in gain according to the cloth type in the low frequency range was observed. Variation in gain caused by moisture variation in the clothes was also observed. This study shows that the parallel R-C connection is proper for electrode model and the resistive factor is influenced by moisture in the clothes. This study is the first that provides the frequency response of the electrode in the actual indirect-contact ECG measurement and it is expected that the results will be helpful to improve the indirect-contact ECG method.

An update on immunotherapy with PD-1 and PD-L1 blockade

  • Koh, Sung Ae
    • Journal of Yeungnam Medical Science
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    • v.38 no.4
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    • pp.308-317
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    • 2021
  • Cancer is the leading cause of death and is on the rise worldwide. Until 2010, the development of targeted treatment was mainly focused on the growth mechanisms of cancer. Since then, drugs with mechanisms related to tumor immunity, especially immune checkpoint inhibitors, have proven effective, and most pharmaceutical companies are striving to develop related drugs. Programmed cell death-1 and programmed cell death ligand-1 inhibitors have shown great success in various cancer types. They showed durable and sustainable responses and were approved by the U.S. Food and Drug Administration. However, the response to inhibitors showed low percentages of cancer patients; 15% to 20%. Therefore, combination strategies with immunotherapy and conventional treatments were used to overcome the low response rate. Studies on combination therapy have typically reported improvements in the response rate and efficacy in several cancers, including non-small cell lung cancer, small cell lung cancer, breast cancer, and urogenital cancers. The combination of chemotherapy or targeted agents with immunotherapy is one of the leading pathways for cancer treatment.

The influence of extremely low frequency magnetic field on cardiovascular response

  • Kim, Jeong-Soo;Jeong, Ji-Hoon;Sung, Ji-Hyun;Bae, Ki-Lyong;Kum, Chan;Kang, Hee-Yun;Sohn, Uy-Dong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.274.1-274.1
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    • 2002
  • There have been some reports showing that cardiovascular response is affected by exposure to extremely low frequency magnetic field (ELF-MF). In this experiment. we intended to observe if ELF-MF affects the basal level of cardiovascular response and effect of drugs acting on sympathetic nervous system. Rats exposed to MF (60 Hz. 20 G) for 1 or 5 days and sham were anesthetized with pentobarbital-Na. Carotid artery and jugular vein were intubated to measure blood pressure (BP) and inject drug respectively. (omitted)

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Application of Rasch Analysis to the Modified Oswestry Low Back Pain Disability Questionnaire for Work-Related Low Back Pain Patients (수정된 오스웨스트리 허리기능 장애 설문지의 라쉬분석: 산업장에서의 업무관련 요통환자를 대상으로)

  • Park, So-Yeon;Oh, Jae-Seop;Yi, Chung-Hwi
    • Physical Therapy Korea
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    • v.15 no.3
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    • pp.26-34
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    • 2008
  • The purposes of this study were to assess and modify the original classification categories of the modified Oswestry Low Back Pain Disability Questionnaire (ODQ) and to determine the unidimensionality of the modified ODQ applying Rasch Analysis. The data were obtained from 108 work-related low back pain patients by physical therapists. Construct validity of the scale using the Rasch model required the structure of the rating scale to be modified from 6 response levels to 4 response levels. Eight items from the modified ODQ fit the Rasch model. The items, "pain intensity" and "social life" showed misfit statistics. In general, the order of item difficulty of the remaining 8 items showed a logical item difficulty hierarchy with the "changing degree of pain" item being the most difficult and the "walk" item being the easiest. The results showed that further study is needed to expand the construct of ODQ including additional higher-level items related to work activities. This study may be useful for establishing a standard method to assess the functionality of low back pain patients.

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A comparative study on the cardiovascular function response to maximal exercise of chronic low back pain patients and normal group (최대운동부하시 정상인과 만성요통환자의 심폐계 반응에 대한 비교연구)

  • Um Ki-Mai;Kim Gun-Do;Hwang Myoung-Hoon
    • The Journal of Korean Physical Therapy
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    • v.12 no.3
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    • pp.379-386
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    • 2000
  • This study is aimed to determine the cardiovascular function response to maximal exercise of chronic low back pain patients(N=13) and normal group(N=13). by using BRUCE PROTOCOL, subjects underwent tredmill exercise test. Their cardiovascular function responses during rest and after maximal exercise were compared The responses were analyzed using t-test for SPSS 7.0 program. The Cardiovascular function variables employed at rest time(Vo2, HR. Vo2/kg, VE, Vco2.) and all out time(Vo2peak. HRpeak, Vo2peak/kg, VEpeak. Vco2peak). Result show that : 1 There was no significant difference in Vo2 between chronic low back pain patients and normal group at rest time. However significant difference in Volpeak was observed after maximal exercise( p<.05). 2. There was no significant difference in HR between chronic low back pain patients and normal group at rest time. No significant difference in HRpeak likewise observed. 3. There was no significant difference in Vo2/kg between chronic low back pain patients and normal group at rest time. However significant difference in Vo2peak/kg was observed after maximal exercise load(p<.05). 4. There was no significance in VE between chronic low bark pain patients and normal group at rest time. However significant difference in VEpeak observed after maximal exercise load(p<.05).

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Design of Low Order Cascade Controller to Reduce the Effects of Its Zeros (제어기 영점의 영향을 감소시키는 종속형 저차 제어기의 설계)

  • Kim, Young-Chol;Kim, Jae-Jin
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.57 no.6
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    • pp.1048-1057
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    • 2008
  • This paper represents a design method for PID or low-order controllers cascaded with a linear plant in the unit feedback system where it is required to meet the given time response specifications such as overshoot and settling time. This problem is difficult to solve because the zeros of the controller appear in the numerator of the overall system and thus those zeros may make the time response design difficult. In this paper, we propose a new approach based on the partial model matching and the so called K-polynomial. The partial matching problem is formulated to an optimization problem in which a quadratic function of coefficient errors between a target model and the resulting closed loop system is minimized. For the sake of satisfying the closed loop stability, a set of quadratic constraints associated with the cost function is introduced. As a result, the controller designed meets both time response requirements and the closed loop stability, if any. It is shown through several examples that the present method can be easily applied to these problems.

Investigation of the Cause of High Vibration in a Low Pressure Turbine Casing with Manufacturing Defects by Frequency Response Analysis (주파수 응답해석을 통한 제작공차를 가지는 저압터빈 케이싱의 고진동 원인 규명)

  • Youn, Hee-Chul;Woo, Chang-Ki;Hwang, Jai-Kon
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.24 no.4
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    • pp.463-468
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    • 2015
  • High vibration of a low pressure (LP) turbine casing caused safety problems and life at the facility it was housed in. The main focus of this study was the cause of the high vibration in a low pressure turbine casing with manufacturing defects by frequency response analysis, compared with the results of experiments. Therefore, excited accelerations were obtained from the LP casing fundamental, and frequency responses were analyzed. The measurement and the modal analysis showed that the natural frequency of the LP turbine casing was 61.26 Hz and the excited frequency of the turbine rotor was 60.25 Hz. The manufacturing defect caused a decrease in the casing natural frequency and resulted in the high vibration of the casing because it moved close to the resonant frequency.

An Analysis on Fault Response Characteristics in Low Voltage DC Distribution System (저압직류 배전계통의 고장응답 특성 분석)

  • Noh, Chul-Ho;Gwon, Gi-Hyeon;Song, Jong-Il;Han, Joon;Oh, Yun-Sik;Kim, Chul-Hwan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.65 no.6
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    • pp.911-917
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    • 2016
  • DC-based power system is paid attention as interests in energy efficiency and power quality are increased. However, standardization and researches for commercializing Low Voltage DC(LVDC) distribution system are still insufficient. Protection system, which is closely related with reliability, power quality, safety, and life expectancy of components in power system, is also included. This paper therefore analyzes fault response characteristics in LVDC distribution system as a preliminary study on protection schemes. A stepwise analysis on fault current from both AC/DC converter and DC/DC converter is performed and related expressions are derived. And then, modeling and simulation with various conditions are conducted by using ElectroMagnetic Transients Program (EMTP) to verify analysis results. Based on research results in the paper, direction for development of protection schemes for LVDC distribution system is suggested.