• Title/Summary/Keyword: Low exposure

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Study on the Correlation between Nicotine Concentrations in Environmental Tobacco Smoke and Urinary Cotinine Concentrations of Nonsmokers (비흡연자의 Nicotine에 대한 노출량과 뇨중 Cotinine 농도의 상관성에 관한 연구)

  • Roh, Jin-Ho;Shin, Dong-Chun;Kim, Jong-Man;Chung, Yong
    • Environmental Analysis Health and Toxicology
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    • v.5 no.3_4
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    • pp.47-56
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    • 1990
  • Smoking damages nonsmoker's health who have been exposed to passive smoking as well as smoker's own health. Passive smoking can cause serious health damage to particular groups, such as the old aged, children and pregnant women. The purpose of this study is to investigate the relationship between nicotine concentrations in environmental tobacco smoke (ETS) and urinary cotinine concentrations of nonsmokers exposed to ETS, and to provide basic information related to health risk assessment. The results of this study were summarized as follows: 1. When 180 cigarrette were smoked during S hours (high concentrations exposure) in 132 m$^3$chamber, mean concentrations of nicotine in ETS showed 263.52 $\mu\textrm{g}$/m$^3$${\pm}$51.93. When 45 cigarretts were smoked (low concentrations exposure), it was 69.43${\pm}$8.96 $\mu\textrm{g}$/m$^3$. 2. The urinary cotinine concentrations of each times (0, 2.5, 5, 17 and 24 hours) in nonsmokers ranged from 0.27∼12.52 ng/ml in high concentrations exposure and 0.22∼2.28 ng/ml in low concentrations exposure. Mean while the total urinary cotinine concentrations during 24 hours ranged from 11.62∼31.65 ng/ml in high concentrations exposure and 3.45∼5.64 ng/ml in low concentrations exposure. 3. The correlation equation and coefficient between cotinine concentrations in nonsmokers' urine (y) and nicotine concentrations in ETS (x) was y=0.421+0.0171x and 0:875 (p<0.01) respectively, 4. The quantity of nonsmokers' smoking exposure by passive smoking can be assumed as based on the estimation of nicotine concentrations in ETS by measuring cotinine concentrations of nonsmokers' urine.

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Use of Metallothionein-Transgenic and Null Mice to Determine the Role of Metallothionein in Cadmium Toxicity

  • Klaassen, Curtis D.
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.42-58
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    • 2002
  • Acute Cd exposure produces hepatotoxicity, whereas chronic Cd exposure produces nephrotoxicity, hematotoxicity, immunotoxicity and bone damage. Previous experiments suggest that the low-molecular-weight, metal-binding protein metallothionein (MT) in liver protects against liver injury, but is responsible for the kidney injury observed after chronic Cd exposure.(omitted)

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Are Medical Personnel Safe from Radiation Exposure from Patient Receiving Radioiodine Ablation Therapy? (갑상선 암의 방사성요오드 치료 시 의료진은 방사선 피폭으로부터 안전한가?)

  • Kim, Chang-Guhn;Kim, Dae-Weung
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.4
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    • pp.259-279
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    • 2009
  • Radioiodine ablation therapy has been considered to be a standard treatment for patient with differentiated thyroid cancer after total thyroidectomy. Patients may need to be hospitalized to reduce radiation exposure of other people and relatives from radioactive patients receiving radioiodine therapy. Medical staffs, nursing staffs and technologists sometimes hesitate to contact patients in radioiodine therapy ward. The purpose of this paper is to introduce radiation dosimetry, estimate radiation dose from patients and emphasize the safety of radiation exposure from patients treated with high dose radioiodine in therapy ward. The major component of radiation dose from patient is external exposure. However external radiation dose from these patients treated with typical therapeutic dose of 4 to 8 GBq have a very low risk of cancer induction compared with other various risks occurring in daily life. The typical annual radiation dose without shielding received by patient is estimated to be 5 to 10 mSv, which is comparable with 100 to 200 times effective dose received by chest PA examination. Therefore, when we should keep in mind the general principle of radiation protection, the risks of radiation exposure from patients are low and the medical personnel are considered to be safe from radiation exposure.

A Study on the Exposure Assessment of Extremely Low Frequency Magnetic Fields (극저주파 자계의 노출 평가에 대한 연구)

  • Kim, Eung-Sik;Kim, Myeong-Hun;Min, Suk-Won
    • Journal of the Korean Society of Safety
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    • v.32 no.1
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    • pp.33-40
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    • 2017
  • This paper addresses the assessment methods used to evaluate the magnetic exposure of a human to ELF EMF (Extremely Low Frequency Electromagnetic Field) which is caused by the process of power delivery from 60 Hz commercial power. These days the main concern is primarily focused on the magnetic field. For the exposure assessment, both numerical studies and laboratory experiments were studied and the results of the two compared for methodological suitability. The numerical analyses employ the Impedance Method (IM), Boundary Element Method (BEM), and Finite Element Method (FEM) and the laboratory experiments used various human phantom models made with conductivities congruent to human organs and then exposed to uniform/non-uniform magnetic fields to produce eddy currents. Under these conditions a number of examples have been evaluated and the reliability assessed to present the pros and cons of each methodology.

Health Risk Assessment for Artificial Turf Playgrounds in School Athletic Facilities: Multi-route Exposure Estimation for Use Patterns

  • Kim, Ho-Hyun;Lim, Young-Wook;Kim, Sun-Duk;Yeo, In-Young;Shin, Dong-Chun;Yang, Ji-Yeon
    • Asian Journal of Atmospheric Environment
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    • v.6 no.3
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    • pp.206-221
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    • 2012
  • Hazardous chemicals can be released from artificial turf used in some school playgrounds. To distinguish between Health risk assessment (HRA) exposure scenarios for this study, the ratio of elementary, middle and high schools was considered before final selection. Considering exposure pathways (inhalational, oral and dermal), media and materials were examined, targeting hazardous chemicals released from artificial turf playground-related products. Upon evaluation, the quantity of infill chips was shown to exceed the domestic product content standard (90 mg/kg) at eight (16%) out of 50 schools. PAHs were shown to exceed standards (10 mg/kg) at two (4%) out of the 50 schools. The excess cancer risk (ECR) of carcinogens was shown to be $1{\times}10^{-6}$ in most users for the worst exposure scenario. In children with pica, who represented the most extreme exposure group, the ECR was expected to be as high as $1{\times}10^{-4}$, showing the low risk level of carcinogens. The hazard index (HI) for individual chemicals was shown to be low, at around 0.1 or less, except for children with pica, according to the mean exposure scenario of artificial turf playground exposure. However, the HI was shown to exceed 1.0 in children with pica. Therefore, no direct health risk was found in using artificial turf playgrounds and urethane flooring tracks for the mean exposure scenario, except in children with pica.

Evaluation of Exposure to Isocyanates Used in Furniture Industry (가구산업에 사용되는 이소시안화물 폭로에 대한 평가)

  • Lee, Su-Gil;Lee, Nae-Woo;Pisaniello, Dino. L
    • Journal of the Korean Society of Safety
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    • v.21 no.2 s.74
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    • pp.138-142
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    • 2006
  • Occupational asthma is commonly known to be induced by isocyanate exposure. Spray painters generally use isocyanates for 2-pack spray painting to coat wooden panel surfaces in the furniture industry in South Australia. Due to a lack of actual exposure data, this study conducted environmental and dermal/ocular monitoring from a company in the furniture industry. According to this study, there was no significant airborne contamination, due to the use of high volume low pressure (HVLP) spray guns, low concentration of hardener in paint solutions and appropriate respirator like full face-air line respirator. There was no significant HDI detection in the general work area around the spray booths. Owing to the use of disposable nitrile gloves during the spray painting, no significant dermal exposure was found. According to color monitoring, there was a possible dermal exposure from surfaces in the workplace, unless either protective gloves were worn or appropriate working practices like clean-up process and storage in a secure places. No eye contamination was detected from the spray painters. No significant exposure levels from inhalational, dermal, ocular were found. The area of most concern was work practices.

Conclusions and Suggestions on Low-Dose and Low-Dose Rate Radiation Risk Estimation Methodology

  • Sakai, Kazuo;Yamada, Yutaka;Yoshida, Kazuo;Yoshinaga, Shinji;Sato, Kaoru;Ogata, Hiromitsu;Iwasaki, Toshiyasu;Kudo, Shin'ichi;Asada, Yasuki;Kawaguchi, Isao;Haeno, Hiroshi;Sasaki, Michiya
    • Journal of Radiation Protection and Research
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    • v.46 no.1
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    • pp.14-23
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    • 2021
  • Background: For radiological protection and control, the International Commission on Radiological Protection (ICRP) provides the nominal risk coefficients related to radiation exposure, which can be extrapolated using the excess relative risk and excess absolute risk obtained from the Life Span Study of atomic bomb survivors in Hiroshima and Nagasaki with the dose and dose-rate effectiveness factor (DDREF). Materials and Methods: Since it is impossible to directly estimate the radiation risk at doses less than approximately 100 mSv only from epidemiological knowledge and data, support from radiation biology is absolutely imperative, and thus, several national and international bodies have advocated the importance of bridging knowledge between biology and epidemiology. Because of the accident at the Tokyo Electric Power Company (TEPCO)'s Fukushima Daiichi Nuclear Power Station in 2011, the exposure of the public to radiation has become a major concern and it was considered that the estimation of radiation risk should be more realistic to cope with the prevailing radiation exposure situation. Results and Discussion: To discuss the issues from wide aspects related to radiological protection, and to realize bridging knowledge between biology and epidemiology, we have established a research group to develop low-dose and low-dose-rate radiation risk estimation methodology, with the permission of the Japan Health Physics Society. Conclusion: The aim of the research group was to clarify the current situation and issues related to the risk estimation of low-dose and low-dose-rate radiation exposure from the viewpoints of different research fields, such as epidemiology, biology, modeling, and dosimetry, to identify a future strategy and roadmap to elucidate a more realistic estimation of risk against low-dose and low-dose-rate radiation exposure.

Determination of Driving Rain Index in Korea (국내 유도강우지수의 결정)

  • Ra, Jong-Bum
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.1
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    • pp.36-42
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    • 2017
  • This research was performed to evaluate the level of exposure of buildings to rain in Korea. The impingement of driving rain by wind is evaluated by driving rain index (DRI). Average annual driving rain indexes (AADRI) for 64 stations spread all over Korea have been determined by using the data of wind speed and precipitation obtained from Korea Meteorological Adminstration (KMA). Based on the values, the regions has been classified as low, moderate, and high. No high exposure regions were found in Korea; 22 regions with moderate exposure and 42 regions with low exposure. Although the values are very dependent on climate change, most of Korea except several regions such as Daegwallyeong, Busan, Yeosu, and Jeju island may be evaluated to be the region where exposure of buildings to driving rain is low to moderate.

Short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings following sudden low salinity exposure (급격한 저염분 노출에 따른 참돔 Pagrus major 치어의 단기 행동반응 및 내성 한계에 관한 연구)

  • Sung Jin Yoon
    • Korean Journal of Environmental Biology
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    • v.39 no.4
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    • pp.495-506
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    • 2021
  • In this study, using a continuous behavior measurement technique, the short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings to sudden exposure to low salinity in a controlled environment were observed. The activity of the fingerlings suddenly exposed to 21.4, 17.3, and 9.8 psu increased temporarily at the initial exposure to show irregular swimming behavior, but then recovered a stable activity pattern through rapid salinity adaptation. However, the organisms suddenly exposed to 7.3 and 4.3 psu could not withstand the salinity stress, and their swimming behavior was severely disturbed and all individuals died within 48 hours. The findings suggest that red seabream underwent a temporary salinity stress process at the beginning of the exposure to concentrations of 10.0 psu or higher. At these concentrations, osmotic control was possible within at least 11 hours, so stable metabolic activity was also possible. However, organisms suddenly exposed to concentrations below 5.0 psu exceeded the tolerance to low salinity and the sublethal limit. In red seabream exposed to this concentration range, severe behavioral and metabolic disturbances were observed, and death was observed due to osmotic control failure. In conclusion, a salinity range of 5.0 to 10.0 psu can be predicted to correspond to a concentration range in which the osmotic control ability of the red seabream fingerlings is lost, and sub-lethal reactions occur.

A Study of Visual Evaluation in the Lingerie Look according to the Part of Body Exposure (란제리 룩의 노출 부위에 따른 시각적 평가)

  • Yoon, Jin-Ah;Lee, Myoung-Hee
    • The Research Journal of the Costume Culture
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    • v.14 no.2
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    • pp.320-333
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    • 2006
  • The purpose of this study was to find out differences of visual evaluation according to perceiver's gender, clothing silhouette, and body exposure of the lingerie look. Subjects were 246 college males and females in Seoul. The visual evaluation of the lingerie look was divided into four image dimensions: elegance, individuality, fascination, and activity. Silhouette had significant influences on the perception of elegance and activity. The hourglass silhouettes were evaluated more elegant and active than the tubular silhouettes. The body exposure had significant influences on the evaluation of elegance, individuality, fascination, and activity. The shoulder and the back exposure were estimated high in fascination, the breast exposure low in elegance, and the waist exposure high in individuality and activity. Individuality, fascination, and activity had interaction effects by perceiver's gender and body exposure. Males estimated the waist exposure to be more fascinating than females, and females estimated the breast exposure to be less active than males. There were significant interaction effects in evaluating the 4 image dimensions according to the silhouette and body exposure. The shoulder and the leg exposure of the hourglass silhouettes were estimated more elegant than those of the tubular silhouettes. Dimensions of clothing image which influenced on preference of lingerie look were different between males and females.

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