• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.7
• /
• pp.4205-4208
• /
• 2013

Objective: The aim of this study was to explore change and significance of serum carcino-embryonic antigen (CEA) before and after gefitinib therapy in patients with advanced non-small-cell lung cancer (NSCLC). Methods: Forty patients with advanced NSCLCs in III~IV stages were selected as study objects given gefitinib therapy combined with routine local radiotherapy until tumor progression or intolerable toxicity. After treatment, all patients were divided into control and non-control groups according to the results of evaluation based on RECIST 1.1 (Response Evaluation Criteria in Solid Tumors in 2009). Peripheral fasting blood from all patients was collected in the early morning and serum CEA was assessed by electro-chemiluminescence immunoassay (ECLIA) before and after treatment. Before treatment, patients were divided into high CEA group (CEA level > 50 ng/mL) and low CEA group (CEA level ${\leq}$ 50 ng/mL). Adverse reactions were noted and progression-free survival (PFS) in both groups was recorded after long-term follow-up that ended in December, 2012. Results: There was no difference between control and non-control groups in CEA level before treatment (P>0.05), whereas serum CEA decreased more markedly lower in the control group after treatment (P<0.01). All patients were divided into high CEA group (26) and low CEA group (14) according to serum CEA level. There was no statistically significant difference between two groups in adverse reactions (P>0.05) but the rate in former group was lower. Additionally, survival rates at 9 and 12 months in high CEA group were clearly higher than in the low CEA group (P<0.01). Conclusions: Serum CEA level can serve as a biochemical index to evaluate the prognosis with gefitinib treatment for NSCLC.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.29 no.3
• /
• pp.61-68
• /
• 2015

When medium and large induction motors are driven by 2-level inverters with low switching frequency, induction motors provoke deteriorated performances resulted from large torque ripples, flux ripples, and large current distortion. Model predictive torque control(MPTC) for a fast torque control of induction motors is also suffered from large torque ripples when the induction motors are fed by 2-level inverters that are based on 6 active voltage vectors with low switching frequency restricted. To solve this problem, this paper proposes a new MPTC method based on both a 12 active voltage vector and an optimized duty ratio calculation. The proposed control strategy illustrates its effectiveness under the various operating conditions through simulation works.

• 제어로봇시스템학회:학술대회논문집
• /
• 2000.10a
• /
• pp.139-139
• /
• 2000

The subject of this paper is the tole operation for unmanned vehicle. The aim is studied in context of motor control system and algorithms for the mid to low level control of tele operation unmanned vehicle described. Modern, vehicle related researches have been implemented about control, chassis, body and safe쇼 but now is to driving comfort, I.T.S. and human factor, etc. As a result of this fact, unmanned vehicle is main research topic over the world but it is still very expensive and unreasonable. A hierarchical approach is studied in context of motor control system and algorithms for the mid to low level control of tele operation unmanned vehicle described. The real time control and monitoring of longitudinal, lateral, Pitching motion is to be solved by system integration and optimization technique. We show the experimental result about fixed brake range test and acceleration test. And all system is to integrated for driving simulator and unmanned vehicle.

• Journal of Power Electronics
• /
• v.19 no.2
• /
• pp.529-539
• /
• 2019

The modular multilevel converter (MMC) has become a promising topology for high-voltage direct current (HVDC) transmission systems. To control a MMC system properly, the ac-side current, circulating current and submodule (SM) capacitor voltage are taken into consideration. This paper proposes a low-computation indirect model predictive control (IMPC) strategy that takes advantages of the conventional MPC and has no weighting factors. The cost function and duty cycle are introduced to minimize the tracking error of the ac-side current and to eliminate the circulating current. An optimized merge sort (OMS) algorithm is applied to keep the SM capacitor voltages balanced. The proposed IMPC strategy effectively reduces the controller complexity and computational burden. In this paper, a discrete-time mathematical model of a MMC system is developed and the duty ratio of switching state is designed. In addition, a simulation of an eleven-level MMC system based on MATLAB/Simulink and a five-level experimental setup are built to evaluate the feasibility and performance of the proposed low-computation IMPC strategy.

• Biomedical Science Letters
• /
• v.13 no.3
• /
• pp.223-230
• /
• 2007

Low power laser and neuromuscular electrical stimulation have been utilized in many clinical applications for the treatment of musculoskeletal lesion. This study was to investigate the effects of low power He-Ne IR laser and neuromuscular electrical stimulation on the change of the serum biochemical components in experimentally induced muscle injured rats. The twenty Sprague-Dawley male rats were randomly assigned to the 4 groups: the normal group (n=5), the control group (n=5), the low power laser irradiation group (LLI) (n=5) and the neuromuscular electrical stimulation group (NMES) (n=5). The experimentally induced muscle injury was induced by the subcutaneous injection of a 0.1 ml Freund's Complete Adjuvant into the right hind paw and calf muscles in control, LLI and NMES groups. The LLI group was irradiated with He-Ne IR laser for 5 minutes every day during 10 days. Also, the NMES group was electrically stimulated 15 minutes every day during 10 days. The normal and control groups were not received with any therapeutic intervention. The authors performed tests which were the concentration of the serum biochemical components to detect the effects of therapeutic interventions. The results were as follows: 1. The level of the aspartate aminotransferase (AST) was significantly decreased in the LLI and NMES groups compare to the control group. 2. The level of the serum lactate dehydrogenase (LDH) was significantly decreased in the LLI and NMES groups compare to the control group. 3. The level of the serum creatine kinase (CK) was significantly decreased in the LLI and NMES groups compare to the control group. From the results, we could come to the conclusion that low power laser and neuromuscular electrical stimulation could be accelerating healing processes of skeletal muscle injury and further clinical work will be required.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.7 no.3
• /
• pp.95-99
• /
• 2008

This paper proposes a new minimal resource high-level synthesis algorithm for low power design automation. The proposed algorithm executes an efficient approach to minimize the power consumption of the functional units in a circuit during the high level synthesis. In this paper, we visit all control steps one by one to reduce the switching activity in CDFG. The register sharing algorithm determines the minimum register after the life time analysis of all variable. According to property of input signal for functional unit, the proposed method visits all control step one by one and determines the resource allocation with minimal power consumption at each control step in a greedy fashion. The effect of the proposed algorithm has been proved through various filter benchmark to adopt a new scheduling and allocation algorithm considering the low rover.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.24 no.1
• /
• pp.99-111
• /
• 2016

This paper presents an integrated fault diagnosis algorithm for driving motor of In-wheel independent drive electric vehicle. Especially, this paper proposes a method that integrated the high level fault diagnosis and the low level fault diagnosis in order to improve a robustness and performance of the fault diagnosis system. The high level fault diagnosis is performed using the vehicle dynamics analysis and the low level fault diagnosis is carried using the motor system analysis. The validity of the high level fault diagnosis algorithms was verified through $Carsim^{(R)}$ and MATLAB/$Simulink^{(R)}$ cosimulation and the low level fault diagnosis's validity was shown by applying it to a MATLAB/$Simulink^{(R)}$ interior permanent magnet synchronous motor control system. Finally, this paper presents a fault diagnosis strategy by combining the high level fault diagnosis and the low level fault diagnosis.

• Korean Journal of Child Studies
• /
• v.36 no.4
• /
• pp.71-89
• /
• 2015

The present study examined the effects of child maltreatment and self-control on reactive aggression amongst middle-school students and investigated whether students' self-control had any form of moderating effect on the relationship between child maltreatment and reactive aggression. The participants of this study consisted of 482 students (204 boys and 278 girls) from four middle schools located in Seoul and Gyoung-gi province. The Peer Conflict Scale (Marsee, Kimonis, & Frick, 2004) was used to measure the level of reactive aggression. The level of child maltreatment was assessed by means of the Child Trauma Questionnaire (Bernstein & Fink, 1998). Self-control was measured by the Self-Control Scale (Nam, 1999). Statistical analyses of data used for this study comprised the following methods; frequency, mean, standard deviation, and hierarchical regression. The moderating effect of self-control was analyzed by using the procedures proposed by Baron and Kenny (1986). The results indicated that the level of child maltreatment increased the level of reactive aggression whereas the level of self-control decreased the level of reactive aggression. In addition, self-control moderated the influence of child maltreatment on student's reactive aggression. As a result, the influence of child maltreatment upon reactive aggression was greater when the level of self-control was low, compared to when it was high.

• Journal of the Korean Dietetic Association
• /
• v.17 no.4
• /
• pp.416-428
• /
• 2011

This study was carried out to investigate the effects of breakfast service on nutritional status, hematological status, and attentiveness of children in low-income families. The subjects were 19 boys and 13 girls between 7 and 11 years old. The subjects were divided into a control group and a breakfast service (BS) group, in which 12 boys and 5 girls received breakfast from February 1 to December 31, 2010. The results can be summarized as follows: intakes of energy, protein, carbohydrate, calcium, iron, zinc, vitamin A, vitamin $B_2$, niacin, and vitamin C in the BS group were significantly higher than those in the control group. In the BS group, the intakes of calcium, folic acid, and vitamin C were lower than 75% of recommended intake levels. There were no significant differences in the total blood protein level and total cholesterol level between the BS group and control group. A blood albumin level was significantly higher in the BS group than in the control group. Systolic blood pressure was higher in the BS group than in the control group, whereas the diastolic blood pressure showed no significant difference between the groups. A dietary attitude score increased according to breakfast service and nutritional education. No significant differences were found in the capacity value and continuity value between the two groups, but the control value was significantly higher in the BS group than in the control group. Therefore, to sustain the effect of breakfast service and improve nutritional status for children skipping breakfast in low-income families, nutrition intervention services, as well as legal and financial support by the government should be provided.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.25 no.5A
• /
• pp.726-742
• /
• 2000

A novel rte control algorithm consisting of two major components, i.e. a variable encoding frame rate method and a hybrid DCT/wavelet I-frame coding scheme, is proposed in this work for low bit rate video coding. Most existing rate control algorithms for low bit rate video focus on bit allocation at the macroblock level under a constant frame rate assumption. The proposed rate control algorithm is able to adjust the encoding frame rate at the expense of tolerable time-delay. Furthermore, an R-D optimized hybrid DCT/wavelet scheme is used for effective I-frame coding. The new rate-control algorithm attempts to achieve a good balance between spatial quality and temporal quality to enhance the overall human perceptual quality at low bit rates. It is demonstrated that the rate control algorithm achieves higher coding efficiency at low bit rates with a low additional computational cost. The variable frame rate method and hybrid I-frame coding scheme are compatible with the bi stream structure of H.263+.