• Journal of the Korean Data and Information Science Society
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• v.28 no.3
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• pp.483-492
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• 2017

Precipitation is one of key components in hydrological modeling and water balance studies. A comprehensive, optimized and sustainable water balance monitoring requires the availability of accurate precipitation data. The amount of precipitation measured in a gauge is less than the actual precipitation reaching the ground. The objective of this study is to determine the wind-induced under-catch of solid precipitation and develop a continuous adjustment function for measurements of all types of winter precipitation (from rain to dry snow), which can be used for operational measurements based on data available at standard automatic weather stations. This study provides Bayesian analysis for the systematic structure of catch ratio in precipitation measurement.

• Molecules and Cells
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• v.25 no.4
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• pp.566-571
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• 2008

Calcineurin (Cn) is a calcium/calmodulin-dependent serine/threonine protein phosphatase that has diverse functions in different cell types and organisms. We screened proteins interacting with the C. elegans CnA homolog, TAX-6, by the yeast two-hybrid system. CNP-3 (Calcineurin interacting protein-3) is a novel protein that physically interacts with the catalytic domain of TAX-6. It is strongly expressed in the nuclei of intestine, hypodermis, dorsal uterine regions and spermatheca. Expression begins around the 60-cell stage and proceeds during all larval stages and the adult. To elucidate the biological function of cnp-3 we isolated a cnp-3 deletion mutant. Since CNP-3 binds CnA, we looked at factors associated with calcineurin loss-of-function mutants, such as brood size, body size, serotonin- and levamisole-mediated egg-laying behavior. The cnp-3(jh145) single mutant had no gross defects compared to wild-type animal. However, the phenotypes of the double mutants, tax-6(p675);cnp-3(jh145) and cnb-1(jh103);cnp-3(jh145), were more severe in terms of brood size, body size and serotonin-mediated egg-laying defects than tax-6(p675) and cnb-1(jh103), respectively. These results suggest that dysfunction of cnp-3 enhances certain calcineurin loss-of-function phenotypes in C. elegans.

• Clinical and Experimental Pediatrics
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• v.53 no.11
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• pp.921-930
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• 2010

Juvenile rheumatoid arthritis (JRA) is the most common rheumatic childhood disease; its onset is before 16 years of age and it persists for at least 6 weeks. JRA encompasses a heterogeneous group of diseases that is classified according to 3 major presentations: oligoarthritis, polyarthritis, and systemic onset diseases. These presentations may originate from the same or different causes that involve interaction with specific immunogenetic predispositions, and result in heterogeneous clinical manifestations. An arthritic joint exhibits cardinal signs of joint inflammation, such as swelling, pain, heat, and loss of function; any joint can be arthritic, but large joints are more frequently affected. Extra-articular manifestations include high fever, skin rash, serositis, and uveitis. The first 2 types of JRA are regarded as T helper 1 (Th1) cell-mediated inflammatory disorders, mainly based on the abundance of activated Th1 cells in the inflamed synovium and the pathogenetic role of proinflammatory cytokines that are mainly produced by Th1 cell-stimulated monocytes. In contrast, the pathogenesis of systemic onset disease differs from that of other types of JRA in several respects, including the lack of association with human leukocyte antigen type and the absence of autoantibodies or autoreactive T cells. Although the precise mechanism that leads to JRA remains unclear, proinflammatory cytokines are thought to be responsible for at least part of the clinical symptoms in all JRA types. The effectiveness of biologic therapy in blocking the action of these cytokines in JRA patients provides strong evidence that they play a fundamental role in JRA inflammation.

• Journal of the Korean Society of Clothing and Textiles
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• v.28 no.11
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• pp.1524-1535
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• 2004

The purpose of this study was to develop middle school girl's' school uniform sizing system according to their body types. The data collected with anthropometric measurements from 390 middle school girls aged 12-15 years old was analyzed using t-test, ANOVA, factor analysis and cluster analysis. A new sizing system was developed in accordance with each of the 2 body-type clusters. The analysis of two-way distribution of 'height-bust girth' and 'height-waist girth' was conducted for the girls of the first grade, which is the time when they purchase their school uniforms. The interval of sizing system was defined in consideration with the most efficient distribution of the body sizes utilizing Loss Function. This study also provided Reference-Sizes and Growth-Allowance Measures for each sizing system to help pattern drafting and clothing construction of the uniform manufacturers. The cover ratio of sizing system proposed by this study was higher when compared with that of the National Agency for Technology and Quality and uniform manufacturing companies, Thus, the result of this study is expected to make up the current sizing system of the school uniform.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.10
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• pp.1852-1859
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• 2016

The effectiveness of a binarization algorithm in image processing depends on how to eliminate the uncertainty of determining threshold in a reasonable way and on minimizing information loss due to the binarization effect. Fuzzy binarization technique was proposed to handle that uncertainty with fuzzy logic. However, that method is known to be inefficient when the given image has low intensity contrast. In this paper, we propose an improved fuzzy binarization method to overcome such known drawbacks. Our method proposes a trapezoid type fuzzy membership function instead of most-frequently used triangle type one. We also propose an adaptive ${\alpha}$_cut determination policy. Our proposed method has less information loss than other algorithms since we do not use any stretching based preprocessing for enhancing the intensity contrast. In experiment, our proposed method is verified to be more effective in binarization with less information loss for many different types of images with low intensity contrast such as night scenery, lumber scoliosis, and lipoma images.

• Journal of Biosystems Engineering
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• v.14 no.1
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• pp.41-48
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• 1989

In order to provide a basic information for the government policy in the future, rice milling costs of Small Capacity Farm-house Rice Whiteners (SCFRW) were estimated by surveying and analyzing the major factors to affect their costs. Two types of SCFRW having one stage and two stage milling process and two rice varieties, Tong-il and Akibare, were considered for their cost estimation, respectively. Also, their costs were compared with those of Private Custom-work Mill in order to determine its economical feasibility. The results were concluded as follows; 1. Major factors to affect the costs were annual milling quantity, purchase price of SCFRW and grain milling loss. 2. Total milling costs of SCFRW were a function of annual milling quantity. These costs decreased rapidly as annual milling quantity increased. 3. In comparison of milling costs between single pass type and double pass type SCFRW, the former was more economical than the latter. 4. Also, in comparison of milling costs between two varieties by using SCFRW, Akibare was less expensive than Tong-il. 5. In comparison with private Custom-work Mill, both single pass and double pass type SCFRW were less economical than private Custom-work Mill. 6. In order to have an economical feasibility, SCFRW should be designed and developed to reduce its milling loss and purchase price.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.5
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• pp.367-371
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• 2001

The chromosome 7-linked long QT syndrome (LQT2) is caused by mutations in the human ether-a- go-go-related gene (HERG) that encodes the rapidly activating delayed rectifier $K^+$ current, $I_{Kr},$ in cardiac myocytes. Different types of mutations have been identified in various locations of HERG channel. One of the mechanisms for the loss of normal channel function is due to membrane trafficking of channel protein. The decreased channel function in some deletion mutants appears to be due to loss of coupling with wild type HERG to form the functional channel as the tetramer. Most of missense mutants with few exceptions could interact with wild type HERG to form functional tetramer and caused dominant negative suppression with co-injection with wild type HERG showing variable effects on current amplitude, voltage dependence, and kinetics of activation and inactivation. Two missense mutants at pore regions of HERG found in Japanese LQT2 (A614V and V630L) showed accentuated inward rectification due to a negative shift in steady-state inactivation and fast inactivation. One mutation in S4 region (R534C) produced a negative shift in current activation, indicating the S4 serving as the voltage sensor and accelerated deactivation. The C-terminus mutation, S818L, could not express the current by mutant alone and did not show dominant negative suppression with co-injection of equal amount of wild type cRNA. Co-injection of excess amount of mutant with wild type produced dominant negative suppression with a shift in voltage dependent activation. Therefore, multiple mechanisms are involved in different mutations and functional abnormality in LQT2. Further characterization with the interactions between various mutants in HERG and the regulatory subunits of the channels (MiRP1 and minK) is to be clarified.

• Corrosion Science and Technology
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• v.13 no.4
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• pp.130-138
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• 2014

Wall thinning can be classified into three types: flow-accelerated corrosion, cavitation erosion and solid particle erosion. This article presents a study of solid particle erosion, which frequently causes damages to power plants' pipe system. Unlike previous studies, this study uses a mechanism to make solid particles in a fluid flow collide with pipe materials in underwater condition. Experiment is conducted in three cases of velocity according to solid-water ratio using the three types of the materials of A106B, SS400, and A6061. The experiments were performed for 30 days, and the surface morphology and hardness of the materials were examined for every 7 days. Based on the velocity change of the solid particles in a fluid flow, the surface changes, the change in the amount of erosion, the erosion rate and the variation in the hardness of carbon steel and aluminum family pipe materials can all be determined. In addition, factor-based erosion rates are verified and a wall-thinning relation function is suggested for the pipe materials.

• Transactions on Electrical and Electronic Materials
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• v.11 no.5
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• pp.238-241
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• 2010

The purpose of this study is to solve the problems of radio frequency bandwidth frequency depletion, confusion possibilities, and security that are in current wireless communications systems, and to confirm the possibility of applying those solutions for the next generation network. To solve the problems of the current wireless communications system, a visible light communications system for power line communication (PLC) via 8-bit microcontroller is created and the capacity is analyzed. The exclusive PLC chip APLC-485MA, an 8-bit ATmega16 microcontroller, high brightness 5pi light emitting diodes (LEDs), and the LLS08-A1 visible light-receiving sensor were used for the transmitter and receiver. The performance was analyzed using a designed program and an oscilloscope. The voltage change was measured as a function of distance from 10-50 cm. Blue LEDs showed the best performance among the measured LED types, with 0.47 V of voltage loss, but for a distance over 50 cm, precise data was not easy to obtain due to the weak light. To overcome these types of problems, specific values such as the changing conditions and efficiency value relevant to the light emitting parts and the visible light-receiving sensor should be calculated, and continuous study and improvements should also be realized for better communication conditions.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.7
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• pp.1416-1425
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• 2002

In this study, the effects of combined environmental factors on mechanical and thermal analysis properties of graphite/epoxy composites were evaluated by the use of an accelerated aging test. Environmental factors such as temperature, moisture. and ultraviolet were considered. A xenon-arc lamp was utilized for ultraviolet light. and exposure times of up to 3000 hours were applied. Several types of specimens - tensile. bending, and shear specimens those are transverse to the fiber direction, and bending specimens those are parallel to the tiber direction - were used to investigate the effects of environmental factors on mechanical properties of the composites. Also, glass transition temperature, storage shear modulus, loss shear modulus, and tan ${\delta}$ were measured as a function of exposure times through a dynamic mechanical analyzer. In addition. a suitable testing method for determining the effect of environmental factors on mechanical properties is suggested by comparing the results from using two different types of strain measuring sensors. Finally, composite surfaces exposed to environmental factors were examined using a scanning electron microscope.