• Title/Summary/Keyword: Lonicera japopnica flower

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Effect of Lonicera Japonica Flower on CCl4-induced Hepatotoxicity (사염화탄소 유발 간독성에 대한 금은화의 작용)

  • 박선관;최병기;이은방
    • Biomolecules & Therapeutics
    • /
    • v.10 no.1
    • /
    • pp.32-36
    • /
    • 2002
  • Methanol extract of Lonicera Japonica (Caprifoiaceae) flower significantly inhibited serum GPT, GOT, LDH and AIP activities at the doses of 500 and 1,000mg/kg in $CCl_4$-intoxicated rats. As confirmed with the fiactions of hexane, chlorofom, ethyl acetate, butanol and water, the butanol fraction showed significant inhibition of increased activity of serum GPT, LDH and AIP in $CCl_4$-intoxicated rats, indicating that the most active components might be contained in the butanol fraction.