• Korean Journal of Biological Psychiatry
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• v.23 no.4
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• pp.185-192
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• 2016

Objectives Treatment response of bipolar disorders (BDs) to long-term mood stabilizers maintenance has not been well explored because of complicated clinical and treatment courses. This study aims at investigating long-term clinical response of BDs to lithium and/or valproate in a naturalistic setting of a tertiary-care university-affiliated hospital. Methods Subjects were 65 patients with bipolar I (BD-I) disorders who had been treated with lithium and/or valproate for more than two years at single bipolar disorder clinic. Long-term response to the best treatment based on treatment algorithms and the current clinical standard of care was retrospectively evaluated using the Alda Scale and the Clinical Global Impression Scale for use in bi-polar illness (CGI-BP). Patients were classified into full responder and partial/non responder groups based on the total score of the Alda Scale with the cut-off score generated from the frequentist mixture analysis of the authors' previous study. Results The mean duration of treatment with the index medication was 69.2 months. Baseline demographic and clinical characteristics were not different among three mood stabilizer groups (valproate, lithium, and combination groups). Twenty-one subjects were classified into full responder group (32.3%). Treatment response assessed by the Alda Scale and CGI-BP scores was not different between lithium and valproate groups. The Alda Scale scores were well correlated with the CGI-BP scores (p < 0.05). Conclusions One third of the patients showed a full response to the long-term lithium and/or valproate treatment in BD-I. The degree of response was similar between lithium and valproate groups.

• Proceedings of the KIEE Conference
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• 2008.11a
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• pp.160-162
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• 2008

This paper present a practical method for long-term voltage stability simulation based on a governor-response power flow. Governor-response power flow (GPF) is to model the long-term system response in the interval from 3 to 30 seconds after disturbance. In this paper, it is assumed that the GPF model ran capture the system state before load restoration starts in contingent conditions. This paper discusses the applicability of GPF to long-term simulation for voltage stability analysis and then explains the GPF formulation and the procedure of the proposed simulation. In addition the paper includes the simulation results with the modified New England 39-bus system.

• Asia-Pacific Journal of Business
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• v.14 no.1
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• pp.73-91
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• 2023

Purpose - The purpose of this study is to re-examine the disclosure effect of stock splits and long-term performance after stock splits using stock split data over the past 10 years, and infer the motivation (signal or opportunism) of stock splits. In addition, we focus on exploring the determinants of the short- and long-term market response to stock splits. Design/methodology/approach - We measure the short-term market response to a stock split and the long-term stock performance after the stock split announcement using the event study method. We analyze whether there is a difference in the long-term and short-term market response to a stock split according to various company characteristics through univariate analysis and regression analysis. Findings - In the case of the entire sample, a statistically significant positive excess return is observed on the stock split announcement date, and the excess return during the 24-month holding period after the stock split do not show a difference from zero. In particular, the difference between short-term and long-term returns on stock splits is larger in companies with a large stock split ratio, small companies, large growth potential, and companies with a combination of financial events after a stock split. Research implications or Originality - The results of this study suggest that at least the signal hypothesis for a stock split does not hold in the Korean stock market. On the other hand, it suggests that there is a possibility that a stock split can be abused by the manager's opportunistic motive, and that this opportunism can be discriminated depending on the size of the stock split, corporate characteristics, and financing plan.

• Proceedings of the Korea Concrete Institute Conference
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• 2004.11a
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• pp.337-340
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• 2004

In recent days, the beneficial effects of using fiber reinforced concrete, especially Steel Fiber Reinforced Concrete, have been on the rise. However, few studies on long-term behavior of SFRC are executed in spite of great demand of SFRC. The fact that SFRC is far better than NRC in various properties such as tensile strength, ductility, flexural toughness has been certified by many researchers. And, those advantages can be also applied to decrease the structures deterioration induced by creep and shrinkage. Furthermore, even though it is fact that SFRC is generally used in joint members to distribute concentrated stresses by fibers, SFRC is treated as NRC in designing especially for long-term behavior of structures. So this paper is about a study on the long-term response of SFRC applied to HPC about 40MPa. Therefore, in this paper, the test results of eighteen high-strength concrete specimens and steel fiber-reinforced concrete specimens, with steel fiber content of $1\%$ by volume were presented. The test result shows that SFRC is advantageous rather than NRC in long-term response.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.923-928
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• 2022

Wildfire disasters in the United States impact lives and livelihoods by destroying private homes, businesses, community facilities, and infrastructure. Disaster victims suffer from damaged houses, inadequate shelters, inoperable civil infrastructure, and homelessness coupled with long-term recovery and reconstruction processes. Cities and their neighboring communities require an enormous commitment for a full recovery for as long as disaster recovery processes last. State, county, and municipal governments inherently have the responsibility to establish and provide governance and public services for the benefit and well being of community members. Municipal governments' comprehensive and emergency response plans are the artifacts of planning efforts that guide accomplishing those duties. Typically these plans include preparation and response to natural disasters, including wildfires. The standard wildfire planning includes and outlines (1) a wildfire hazard assessment, (2) response approaches to prevent human injury and minimize damage to physical property, and (3) near- and long-term recovery and reconstruction efforts. There is often a high level of detail in the assessment section, but the level of detail and specificity significantly lessons to general approaches in the long-term recovery subsection. This paper aims to document the extent of wildfire preparedness at the county level in general, focusing on the long-term recovery subsections of municipal plans. Based on the identified challenges, the researchers provide recommendations for better longer-term recovery and reconstruction opportunities: 1) building permit requirements, 2) exploration of the use of modular construction, 3) address through relief from legislative requirements, and 4) early, simple, funding, and the aid application process.

• Journal of Environmental Health Sciences
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• v.46 no.5
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• pp.599-609
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• 2020

Objectives: Coronavirus disease 2019 (COVID-19) first emerged in December 2019 in Wuhan, China, and has rapidly become a global pandemic with over 26.4 million confirmed cases and approximately 871,000 fatalities worldwide as of this writing. In the Republic of Korea, disease clusters frequently occurred in long-term care hospitals where the majority of residents are elderly with underlying medical conditions. Despite the fact that public health authorities and local community health centers have put tremendous efforts into preventing the spread of disease, positive cases have continued to occur. Thus, the Korea Centers for Disease Control & Prevention rapid response team decided to conduct an environmental investigation of a long-term care hospital to identify whether environmental contamination has remained and contributed to the spread of COVID-19. Methods: An environmental investigation was conducted at Hospital A. The characteristics of the facility and its HVAC system were assessed by checking the layout and interviewing the people in charge. A total of 64 surface samples were collected from areas of concern, including patient rooms, toilets, elevators, and nurses' station. These samples were tested by a regional health and environmental research institute using real-time reverse transcription polymerase chain reaction. Results: All samples from Hospital A were confirmed to be negative. Through interviews with high-level personnel at the regional community health center, we found that extensive disinfection is frequently performed on potentially contaminated areas in Hospital A in accordance with government guidelines. Conclusion: The environmental control measures implemented in Hospital A had been sufficient for mitigating the risk of further infection, suggesting that such measures may also be effective for other long-term health care facilities.

• Geomechanics and Engineering
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• v.36 no.1
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• pp.83-97
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• 2024

It is important to make reasonable prediction about the long-term deformation of high rockfill geostructures. However, the deformation is usually underestimated using the rockfill parameters obtained from laboratory tests due to different size effects, which make it necessary to identify parameters from in-situ monitoring data. This paper proposes a novel hybrid back-analysis method with a modified objective function defined for the time-dependent back-analysis problem. The method consists of two stages. In the first stage, an improved weighted average method is proposed to quickly narrow the search region; while in the second stage, an adaptive response surface method is proposed to iteratively search for the satisfactory solution, with a technique that can adaptively consider the translation, contraction or expansion of the exploration region. The accuracy and computational efficiency of the proposed hybrid back-analysis method is demonstrated by back-analyzing the long-term deformation of two high embankments constructed for airport runways, with the rockfills being modeled by a rheological model considering the influence of stress states on the creep behavior.

• Management Science and Financial Engineering
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• v.4 no.2
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• pp.59-75
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• 1998

This paper presents an incentive system to reduce response time from a supplier. The incentive system is expressed as a contract between an assembler and a supplier who have a long-term relationship. We produce the optimal payment scheme and expected total cost, when the assembler is farsighted. We show that the farsighted assembler obtains higher effort level from the supplier than the myopic assembler. We also show that the expected total cost of the farsighted assembler is smaller in the long run, although it is initially higher than that of the myopic assembler.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.742-747
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• 2007

In order to investigate the mechanism of adaptation to long-term heat stress, six female buffalo calves of about 7 to 8 months age, were exposed to the cool-comfort environment (THI 65) for 21 days to obtain normal values of blood acid-base. An adaptive response of acid-base regulation was determined to long term (21 days) exposure of buffalo calves to hot-dry (THI 80) and hot-humid (THI 84) conditions. Higher rectal temperature and respiratory rate was recorded under hot-humid exposure compared to hot-dry. Significant reduction in the rectal temperature and respiratory rate on day 21 of hot-dry exposure indicated early thermal adaptation compared to hot-humid. Decreasing rectal temperature and respiratory rate from day 1 to 21 was associated with concurrent decrease in blood pH and pCO2. Increased plasma chloride concentration with low base excess in blood and in extracellular fluid suggested compensatory response to respiratory alkalosis. Reduced fractional excretion of sodium with increased fractional excretion of potassium and urine flow rate indicated renal adaptive response to heat stress.

• International Journal of Ocean Engineering and Technology Speciallssue:Selected Papers
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• v.3 no.1
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• pp.29-34
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• 2000

This paper proposes a long-term prediction of offshore structures in ocean waves. All short-term statistics is generated by the simulation for all the combinations of significant wave heights and spectral peak periods. The simulation has been tested first on linear system, whose analytic solution is known, to verify if the simulation works accurately. Then the scheme was applied to the nonlinear system. This paper demonstrated that the proposed scheme could be an efficient tool in estimating the response of offshore structures.