• Title/Summary/Keyword: Long-term damage

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Four months of magnetized water supplementation improves glycemic control, antioxidant status, and cellualr DNA damage in db/db mice (제2형 당뇨 모델 db/db 마우스에서 4개월의 자화수 섭취 후 혈당, 항산화 상태 및 세포 DNA 손상 개선 효과)

  • Lee, Hye-Jin;Kang, Myung-Hee
    • Journal of Nutrition and Health
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    • v.49 no.6
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    • pp.401-410
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    • 2016
  • Purpose: Water is magnetically charged upon contact with a magnet. Although magnetic water products have been promoted since the 1930's, they have not received wide acceptance since their effectiveness is still in question; however, some have reported their therapeutic effects on the body, especially the digestive, nervous, and urinary systems. Methods: In this study, the effect of magnetized water on glycemic control of 14 diabetic mice (CB57BK/KsJ-db/db) in comparison with 10 control mice (CB57BK/KsJ-db/+(db/+)) was investigated. Seven diabetic control (DMC) mice and seven diabetic mice + magnetized water (DM+MW) were kept for 16 weeks, followed by intraperitoneal glucose tolerance test (IPGTT). Weekly blood glucose was measured from tail veins. Blood obtained from heart puncture was used for HbA1c analysis. Results: Blood glucose level showed a significant difference starting from the $10^{th}$ week of study ($496.1{\pm}10.2mg/dl$ in DMC vs. $437.9{\pm}76.9mg/dl$ in DM+MW). Blood glucose followed by IPGTT showed no significant difference between groups at 0, 30, 60, 90, and 120 min, although glucose level at 180 min was significantly reduced in DM+MW mice. Plasma insulin level in DM+MW groups was only 39.5% of that of DMC groups ($5.97{\pm}1.69ng/ml$ in DMC vs. $2.36{\pm}0.94ng/ml$ in DM+MW). Levels of HbA1c were 12.4% and 9.7% in DMC and DM+MW groups, respectively. Conclusion: These results show the promising therapeutic effect of magnetized water in regulating blood glucose homeostasis; however, long-term supplementation or mechanistic study is necessary.

Electrolytic Reduction of 1 kg-UO2 in Li2O-LiCl Molten Salt using Porous Anode Shroud (Li2O-LiCl 용융염에서의 다공성 양극 슈라우드를 이용한1kg 우라늄산화물의 전해환원)

  • Choi, Eun-Young;Lee, Jeong;Jeon, Min Ku;Lee, Sang-Kwon;Kim, Sung-Wook;Jeon, Sang-Chae;Lee, Ju Ho;Hur, Jin-Mok
    • Journal of the Korean Electrochemical Society
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    • v.18 no.3
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    • pp.121-129
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    • 2015
  • The platinum anode for the electrolytic reduction process is generally surrounded by a nonporous ceramic shroud with an open bottom to offer a path for $O_2$ gas produced on the anode surface and prevent the corrosion of the electrolytic reducer. However, the $O^{2-}$ ions generated from the cathode are transported only in a limited fashion through the open bottom of the anode shroud because the nonporous shroud hinders the transport of the $O^{2-}$ ions to the anode surface, which leads to a decrease in the current density and an increase in the operation time of the process. In the present study, we demonstrate the electrolytic reduction of 1 kg-uranium oxide ($UO_2$) using the porous shroud to investigate its long-term stability. The $UO_2$ with the size of 1~4mm and the density of $10.30{\sim}10.41g/cm^3$ was used for the cathode. The platinum and 5-layer STS mesh were used for the anode and its shroud, respectively. After the termination of the electrolytic reduction run in 1.5 wt.% $Li_2O-LiCl$ molten salt, it was revealed that the U metal was successfully converted from the $UO_2$ and the anode and its shroud were used without any significant damage.

Ecological Management of Sangnim Woods in Hamyang-gun, Korea by Analysis of Ecological Structure (함양 상림의 환경생태적 구조 분석 및 생태적 관리방안1)

  • 한봉호;김종엽;조현서
    • Korean Journal of Environment and Ecology
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    • v.17 no.4
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    • pp.324-336
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    • 2004
  • This study was achieved to present ecological administration plan by analyzing vegetation structure and condition rating class(environmental damage degree) of Sangnim Woods Natural Monument in Hamyang-gun, Korea. In vegetation structure part, actual vegetation was classified by 22 patterns and Quercus serrata Carpinus tschonoskii community(31.8%), Quercus serrata community(14.6%) ranged extensively. Main plant community was 8 types, and is fractionated by 13 plant communities according to stratigraphy development degree it is Quercus serrata community, Quercus serrata Carpinus tschonoskii community, Quercus aliena community, Quercus acutissima community, Carpinus tschonoskii community, Carpinus tschonoskii Quercus serrata community, Zelkova serrata-Quercus serrata community, and Planted area with korean landscape woody plants. Age of old growth trees that diameter of breast height over 38cm was 61∼77years. In condition rating class, area of class 3 was 51,960$m^2$(32.8%), area of class 4 was 6,583$m^2$(3.5%), and area of class 5 was 4,086$m^2$(2.6%) and gross area of class 3∼6 need artificial restoration was 61,619$m^2$(38.9%). Considering actual vegetation, plant community structure, and condition rating class biotope was classified by total 14 types. While distribution area of Queens spp. old growth forest of shrub damaged(51,246$m^2$, 32.4%) and deciduous broad leaved old growth forest of simple-layer structure(19,906$m^2$, 12.6%) is large and that of deciduous broad-leaved old growth forest of multi-layer structure(2,085$m^2$, 1.3%) and Queens spp. old growth forest of multi-layer structure may have to manage with user control by administration plan for stabilization of Sangnim Woods ecosystem for long-term. Also, both vegetation of shrub damaged and simple-layer structure as negative restoration area should be restored for ecological succession and both grassland and planted area with korean woody plants as positive restoration area should be revegetated by using ecological planting model of native vegetation structure in Sangnim Woods.

The Variation of Benthic Macroinvertebrates Caused by Erosion Control Works in a Torrential Stream - Focused on Variation of Benthic Macroinvertebrates Analyzed immediately after Construction Works - (황폐계류의 사방공작물 시공에 따른 저서성 대형무척추동물상의 변화 - 시공 직후의 변화를 중심으로 -)

  • Lee, Do-Hyung;Lee, Ki-Hwan;Lee, Heon-Ho;Ma, Ho-Seop;Bae, Kwan-Ho;Kim, Jong-Hyon
    • Korean Journal of Environment and Ecology
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    • v.23 no.4
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    • pp.353-364
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    • 2009
  • This study was conducted to evaluate the effect of erosion control works on the stream ecosystem in a mountain torrential stream. The species composition of benthic macroinvertebrates and biological water quality were investigated before and after construction of erosion control works at 5 sites. The total number of benthic macroinvertebrates before construction was 3,086 individuals including 4 phyla, 6 classes, 11 orders, 22 families, and 25 species, but after construction it has decreased to 1,208 individuals including 4 phyla, 6 classes, 10 orders, 17 families, and 19 species. Especially, the diversity, richness, and evenness indices, which were calculated based on existing number of biological species, have decreased or not produced at the erosion control sites, where biological species were not found or the minimum number of species were found. The results of community analysis of benthic macroinvertebrates and ESB(Ecological Score of Benthic macroinvertebrate community) indicated that the environmental qualities of the stream based on saprobity, environmental condition, and water quality decreased after the construction at all sites: before construction, the top of the stream was satisfactory and some satisfactory, the middle was some defectiveness, and the lower was defectiveness and very defectiveness; after construction, all parts of the stream except some parts of the top were very defectiveness. Moreover, the water quality of torrential stream was rated between I to III before construction, but after construction, it declined to $IV{\sim}V$ except control. The habitat damage of benthic macro invertebrates occurred at all investigation sites after the construction of erosion control works led to reduction of the number of biological species and water quality deterioration. The results reported in this study were collected directly after the construction of erosion control works. Therefore, additional studies are needed to further explore the effect of disaster-prevention of erosion control works and the recovery process of stream ecosystem through long term monitoring.

Measurement and Quality Control of MIROS Wave Radar Data at Dokdo (독도 MIROS Wave Radar를 이용한 파랑관측 및 품질관리)

  • Jun, Hyunjung;Min, Yongchim;Jeong, Jin-Yong;Do, Kideok
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.32 no.2
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    • pp.135-145
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    • 2020
  • Wave observation is widely used to direct observation method for observing the water surface elevation using wave buoy or pressure gauge and remote-sensing wave observation method. The wave buoy and pressure gauge can produce high-quality wave data but have disadvantages of the high risk of damage and loss of the instrument, and high maintenance cost in the offshore area. On the other hand, remote observation method such as radar is easy to maintain by installing the equipment on the land, but the accuracy is somewhat lower than the direct observation method. This study investigates the data quality of MIROS Wave and Current Radar (MWR) installed at Dokdo and improve the data quality of remote wave observation data using the wave buoy (CWB) observation data operated by the Korea Meteorological Administration. We applied and developed the three types of wave data quality control; 1) the combined use (Optimal Filter) of the filter designed by MIROS (Reduce Noise Frequency, Phillips Check, Energy Level Check), 2) Spike Test Algorithm (Spike Test) developed by OOI (Ocean Observatories Initiative) and 3) a new filter (H-Ts QC) using the significant wave height-period relationship. As a result, the wave observation data of MWR using three quality control have some reliability about the significant wave height. On the other hand, there are still some errors in the significant wave period, so improvements are required. Also, since the wave observation data of MWR is different somewhat from the CWB data in high waves of over 3 m, further research such as collection and analysis of long-term remote wave observation data and filter development is necessary.

The Effect of Garlic and Medicinal Plants Extracts on the Liver Function and Lipid Metabolism of Rats Administered with Alcohol (마늘과 한약재 추출물의 혼합급이가 알코올 투여에 의한 간기능 및 지질대사에 미치는 영향)

  • Lee, Soo-Jung;Kang, Min-Jung;Shin, Jung-Hye;Kim, Jeong-Gyun;Kang, Shin-Kwon;Sung, Nak-Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.5
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    • pp.561-568
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    • 2009
  • To investigate the effects of garlic and medicinal plants extracts (GP) on liver function and lipid metabolism of rat administered with ethanol chronically, Sprague-Dawly male rats were fed with a basial diet (Normal), a basial diet plus ethanol (Control, 10 mL of 20% ethanol/kg b.w/day), a control diet plus 0.5% garlic and 1.0% medicinal plants extracts (GP-I), and a control diet plus 1.0% garlic and medicinal plants extracts (GP-II) for 4 weeks. Blood glucose in GP group was significantly decreased, but not significantly different between GP-I and GP-II group. Albumin content of serum was significantly increased in GP groups, while total lipid, cholesterol and triglyceride of serum were significantly decreased in GP group. Total cholesterol and triglyceride were not significantly different between GP-I and GP-II group. LDL-cholesterol in blood was decreased to 58% in GP-I group and 73% in GP-II group compared to the control group, it's contents were the lowest amounts among the normal, control and experimented groups. Lipid levels in liver of rat administered with alcohol were decreased in GP group and significantly different in GP-II group. GOT and r-GTP activities were significantly higher in control than normal group, while GPT and ALP activities were not significant in groups administered with alcohol. Activities of GOT, GPT and r-GTP were significantly lower in GP group than control group, while ALP activity was not significant in all groups. TBARS contents were not significant in serum, but it's contents in liver were significantly decreased in GP groups than control group. DPPH radical scavenging ability in serum and liver was significantly increased in GP groups. These results indicate that garlic and medicinal plants extracts were effective in improving and protecting liver disorder induced from long-term alcohol consumption.

Pediatric Urolithiasis: Our 22-year Experience at a Single Center (소아에서의 요로결석: 단일기관에서 22년간의 경험)

  • Kim, Su-Yon;Kim, Min-Jee;Lee, Joo Hoon;Kim, Kun Suk;Park, Young Seo
    • Childhood Kidney Diseases
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    • v.17 no.2
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    • pp.101-109
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    • 2013
  • Purpose: Pediatric urolithiasis is uncommon in children but is a cause of significant morbidity and damage to the kidney. Although much information on adult urolithiasis is available in the literature, large studies on the pediatric population are still scarce. In this report, we review our experience with pediatric urolithiasis over 22 years at a tertiary referral center. Method: We retrospectively reviewed the records of children with newly diagnosed urolithiasis between January 1991 and May 2013. We assessed the age, sex, family history, initial symptoms, location of stones, underlying cause, stone analysis, treatment, and recurrence among the patients. Results: In total, 137 patients (96 male, 41 female) were assessed. The age range was 0-17 years (mean age, 6.0 years). Forty-three (31%) children were aged <1 year, and 37% (16/43) had a history of intensive care unit (ICU) admission. Thirteen patients (9.5%) had a family history of stones. The most common symptoms at presentation among the patients were gross hematuria (56/137, 41%) and flank or abdominal pain (46/137, 34%). The stones were located in the kidney (85/137, 62%), ureter (29/137, 21%), bladder (2/137, 1.4%), and multiple locations (20/137, 15 %). Congenital abnormalities of the genitourinary (G-U) tract, with or without metabolic abnormality, or urinary tract infection (UTI) was detected in 26 children (19%). Ninety-one patients (66%) underwent metabolic examination, and 38% of these patients exhibited an abnormality. UTI, with or without abnormalities of the G-U tract, or metabolic abnormality was detected in 26 children (19%). Of the 35 stones analyzed, the majority were calcium stones (20/35, 57%), followed by infected stones (5/35, 14%), uric acid stones (4/35, 11%), carbonate apatite stones (3/35, 7%), cystine stones (2/35, 6%), and phosphate stones (1/35, 3%). Five patients (4%) required open procedures, with or without non-open procedures, whereas 77 patients (56%) were managed conservatively; the remaining 55 patients (40%) received some other form of intervention. Eighteen patients (13%) had stone recurrence during the follow-up period. Conclusions: Pediatric urolithiasis is commonly associated with abnormalities of the G-U tract and/or metabolic disorders and/or UTI. Half of the patients will pass their stones spontaneously, and all the techniques of minimally invasive surgery are applicable in the treatment of children with stones. As the recurrence rates are high among this population, long-term follow-up is recommended and the complete clearance of stones is important.

A Study on the Present Conditions of Conservation & Management of the Natural Monuments of Korea (국내(國內)의 천연기념물(天然記念物) 보존(保存) 관리(管理) 실태(實態))

  • Na, Moung-Ha;Lee, Jin-Hee;Lee, Jae-Keun
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.28 no.2
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    • pp.127-136
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    • 2010
  • This study is aimed at reviewed and analyzed in order to suggest the improved plans related to natural monuments. The summary of this study is as followings; First, Replacing the current term 'cultural properties', which denotes the meaning of 'goods', we need to devise an new categorization that separates such properties into cultural heritage and natural heritage under the national heritage framework. Second, the designation criteria for natural monuments should be divided into the individual realm for animals and plants respectively, since they are not divided in the current Act. Third, the guidelines for naming of natural monuments should be established with the following new categories in accordance with the clear standards. Fourth, such imbalances require us to give priority to the relatively neglected types and areas. Fifth, as the big and old trees account for more than a half of the designated plants, it is necessary to search out new resources(wet plant communities, seashores, sand dune plant communities, etc.) such as geological resources, mineral springs, hot springs, and fossils that are in danger of completely being exploited and exhausted. While most of the designated animals are protected nationally, the existing designation system is required to protect habitats and breeding places for the systematic and efficient conservation. Sixth, as long as we need to preserve those historical and cultural resources for the future generations from national and global perspectives, we should enhance their values by designating them as natural monuments even though they are protected by other regulations such as the natural environment area. Seventh, as a result of the survey, we found that more budgets and experts in the local governments, more empowered organizations, more active public participation should be provided for the better Natural Monument management in Korea. Eighth, the Lap of Natural Heritage in the National Research Institute of Cultural Heritage needs to be developed to the Natural Heritage Institute to conduct the diverse activities such as researches, restoration, exhibition and education programs in a systematic and efficient way. Ninth and the last, major damages to natural monuments can be generally categorized into the artificial one and natural one, respectively. The artificial damages include toxics, soil covering, excessive humidity, fire, construction and management works, unlawful damages, fishing, oil spillage, etc, and the natural ones include lightning, storms(typhoons), heavy snowfalls, damage by insects and diseases, lack of prey, etc. This study will become meaningful in that it proposes specific measures for the improvement of the institutions, designation, and management of natural monuments on the basis of the comprehensive analysis on natural monuments. We wish to leave the other subjects related with this study to the future researches.

A Long-term Variability of the Extent of East Asian Desert (동아시아 사막 면적의 경년변화분석)

  • Han, Hyeon-Gyeong;Lee, Eunkyung;Son, Sanghun;Choi, Sungwon;Lee, Kyeong-Sang;Seo, Minji;Jin, Donghyun;Kim, Honghee;Kwon, Chaeyoung;Lee, Darae;Han, Kyung-Soo
    • Korean Journal of Remote Sensing
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    • v.34 no.6_1
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    • pp.869-877
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    • 2018
  • The area of desert in East Asia is increasing every year, and it cause a great cost of social damage. Because desert is widely distributed and it is difficult to approach people, remote sensing using satellites is commonly used. But the study of desert area comparison is insufficient which is calculated by satellite sensor. It is important to recognize the characteristics of the desert area data that are calculated for each sensor because the desert area calculated according to the selection of the sensor may be different and may affect the climate prediction and desertification prevention measures. In this study, the desert area of Northeast Asia in 2001-2013 was calculated and compared using Moderate Resolution Imaging Spectroradiometer (MODIS) and Vegetation. As a result of the comparison, the desert area of Vegetation increased by $3,020km^2/year$, while in the case of MODIS, it decreased by $20,911km^2/year$. We performed indirect validation because It is difficult to obtain actual data. We analyzed the correlation with the occurrence frequency of Asian dust affected by desert area change. As a result, MODIS showed a relatively low correlation with R = 0.2071 and Vegetation had a relatively high correlation with R = 0.4837. It is considered that Vegetation performed more accurate desert area calculation in Northeast Asian desert area.

Study on Standardization of the Environmental Impact Evaluation Method of Extremely Low Frequency Magnetic Fields near High Voltage Overhead Transmission Lines (고압 가공송전선로의 극저주파자기장 환경영향평가 방법 표준화에 관한 연구)

  • Park, Sung-Ae;Jung, Joonsig;Choi, Taebong;Jeong, Minjoo;Kim, Bu-Kyung;Lee, Jongchun
    • Journal of Environmental Impact Assessment
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    • v.27 no.6
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    • pp.658-673
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    • 2018
  • Social conflicts with extremely low frequency magnetic field(ELF-MF) exposures are expected to exacerbate due to continued increase in electric power demand and construction of high voltage transmission lines(HVTL). However, in current environmental impact assessment(EIA) act, specific guidelines have not been included concretely about EIA of ELF-MF. Therefore, this study conducted a standardization study on EIA method through case analysis, field measurement, and expert consultation of the EIA for the ELF-MF near HVTL which is the main cause of exposures. The status of the EIA of the ELF-MF and the problem to be improved are derived and the EIA method which can solve it is suggested. The main contents of the study is that the physical characteristics of the ELF-MF affected by distance and powerload should be considered at all stages of EIA(survey of the current situation - Prediction of the impacts - preparation of mitigation plan ? post EIA planning). Based on this study, we also suggested the 'Measurement method for extremely low frequency magnetic field on transmission line' and 'Table for extremely low frequency magnetic field measurement record on transmission line'. The results of this study can be applied to the EIA that minimizes the damage and conflict to the construction of transmission line and derives rational measures at the present time when the human hazard to long term exposure of the ELF-MF is unclear.