• 멤브레인
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• 제10권1호
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• pp.47-53
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• 2000

인공폐는 실제 폐의 기능을 대행하는 장치이며, 주요 기능은 정맥혈에서 이산화탄소를 제거하고 산소를 첨가하여 동맥혈화하여 개심수술시 신체의 모든 조직에 충분한 양의 동맥혈을 공급한다. 또한 체외순환 생명보조장치(ECLS 또는 ECMO)는 심한 호흡부전증에 일반적으로 이용되지만 미래의 폐 이식에 사용될 것이다. 현재 미세다고엉 폴리프로필렌 중공사를 사용하고 있는 막형 인공 폐는 두 가지 문제가 있다. 환자의 체계적인 항응고가 필요하며, 오랜 기간의 사용은 막을 통하여 혈액 쪽에서 가스 쪽으로 혈청 누출을 일으킨다. 본 연구는 미세다공성 폴리프로필렌(PP)막에 폴리디메틸실록산(PDMS)을 적충한 PP/PDMS막을 제조하고, 폴리프로필렌 막에서 유발하는 혈청 누출을 최소화하는 기술에 대하여 연구하였다. Lee-White법에 의한 whole blood의 혈전형성 실험 후 사용된 막의 기체 투과도는 PP막에서는 크게 저하되었지만, PP/PDMS막에서는 거의 동일하게 유지되었다. 그러므로 PP막에서 유발되는 혈청 누출을 PP/PDMS막에서는 해결할 수 있었다. 또한, PP/PDMS막에서는 이산화탄소의 기체토과율이 산소보다 11.5배였다.

• 센서학회지
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• 제23권4호
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• pp.266-271
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• 2014

Chemical sensors are used in various industrial facilities such high-risk and prevent the leakage of substances, important in life and environmental protection and the safe use of industry, used for management. In particular, high-temperature environments such as power generation equipment of the rotating part due to leakage generated by the various oil, power plants Shut Down, fire, work environment (exposure to various chemical solution and gas leak) and various water, air and soil pollution causes. Thus, over the long term through various channels such as crops and groundwater contamination caused by the slow, serious adverse effect on the ecosystem. In this paper, synthetic lube oil and high pressure hydraulic fluid leakage and immediately detect a new Printed Electronic implementation of technology-based film-type sensors, and its performance test. Thus, industrial accidents and environmental pollution and for early detection of problems, large accidents can be prevented. Experimental results of the synthetic lube oil and high pressure hydraulic fluid solution after the contact time depending on the experiment and the oil solution of the sensor material of the conductive porous PE resistance value by a chemical reaction could be confirmed that rapid increase. Also implemented in the film-type oil sensor electrical resistance change over time of the reaction rate and the synthetic lube oil is about 2 minutes or less, the high pressure hydraulic fluid is less than about 1 minute was. Therefore, more high-pressure hydraulic fluid such as a low volatility synthetic lube oils are the resistance change and the reaction rate was confirmed to be the slowest.

• Toxicological Research
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• 제34권1호
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• pp.75-81
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• 2018

Animal experiments have been widely conducted in the life sciences for more than a century, and have long been a subject of ethical and societal controversy due to the deliberate infliction of harm upon sentient animals. However, the harmful use of animals may also negatively impact the mental health of researchers themselves. We sought to evaluate the anxiety level of researchers engaged in animal use to analyse the mental stress from animal testing. The State Anxiety Scale of the State-Trait Anxiety Inventory (STAI) was used to evaluate how researchers feel when they conduct animal, as opposed to non-animal, based experiments (95 non-animal and 98 animal testing researchers). The Trait Anxiety Scale of STAI was employed to measure proneness to anxiety, namely the base trait of the researchers. Additionally, the information on sex, age, education, income, and total working periods was collected. While the Trait Anxiety scores were comparable ($41.5{\pm}10.9$ versus $42.9{\pm}10.1$, p = 0.3682, t-test), the State Anxiety scores were statistically significantly higher for animal users than non-animal users ($45.1{\pm}10.7$ versus $41.3{\pm}9.4$, p = 0.011). This trend was consistent for both male and female. Notably, younger animal testers (${\leq}30$ years of age) with less work experience (${\leq}2$ years) and lower income level (${\leq}27,000$ USD) exhibited higher anxiety scores, whereas these factors did not affect the anxiety level of non-animal users. The present study demonstrated that participation in animal experiments can negatively impact the mental health of researchers.

• 한국학교보건학회지
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• 제16권2호
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• pp.125-134
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• 2003

Purposes of this study were 1) to identify the level of role expectation and role performance for school health educators as elementary school students recognize and to compare them, and 2) to examine differences in the role expectation and performance by characteristics of students and educators. Subjects of the study were 1,433 6th grade students at 37 elementary schools in Busan. The data were collected by a structured self-administered questionnaire, measuring role expectation and performance that students recognize. The data were analyzed with descriptive statistics, t-test, and ANOVA by SPSS program. The results were summarized as follows. 1. Students' level of recognizing the role expectation was high(M=4.08) and level of the role performance was moderate to high(M=3.50) within range of 1 to 5. The students recognized role expectation greater than role performance. 2. The students' point of view for role expectation and performance for school health educators were related to several characteristics of students and school health educators. Students' levels of recognizing the role expectation and performance were higher when students were male, healthy, their academic performance was high, their level of satisfaction with their school life was high, and their level of satisfaction with using school health office was high. With characteristics of School health educators, students' level of appreciating the role expectation was higher when educators were of an older age and had a long career, and when they were fairly satisfied with their job as an educator. Students' level of recognizing the role performance was higher when educators were of a younger age, and had a small number of students at school. This indicates that there exists role conflict on students and implies that the conflict needs to be mediated, and desirable solutions to address the conflict need to be developed by school health educators.

• 한국임상약학회지
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• 제14권2호
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• pp.85-90
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• 2004

Bisoprolol, one of the $\beta_1-adrenorecepter$ antagonist, has been used for the treatment of mild to moderate essential hypertension anti stable angina pectoris. The oral bloavailability of bisoprolo1 is high $(90\%)$ and the drug has a long elimination half-life, $9{\sim}12\;hr$, which allows once-daily administration. The bioequivalence of two bisoprolol preparations was evaluated according to the guidelines of Korea Food & Drug Administration (KFDA). The test product was Concor $tablet^{(R)}$ made by Newgenpharm and the reference product was Monocor $tablet^{(R)}$ made by Wyeth Korea. Twenty healthy male subjects, 23.8 (21-30) years old and 03.8(52-92) kg, were randomly divided into two groups and a randomized $2\times2$ cross-over study was employed. After two tablets containing 10 mg bisoprolol hemifumarate were orally administered, blood was taken at predetermined time intervals and the concentration of bisoprolol in plasma was determined using an HPLC method with fluorescence detector. Two pharmacokinetic parameters, $AUC_t\;and\;C_{max}$ were calculated and analyzed statistical]y for the evaluation of bioequivalence of the two products. Analysis of variance was carried out using logarithmically transformed parameter values. The $90\%$ confidence intervals of $AUC_t\;and\;C_{max}$ were log $0.95{\sim}1og\;1.04\;and\;1og\;0.96{\sim}1og\;1.07,\;respectively.$ These values were within the acceptable bioequivalence intervals of log $0.8{\sim}log\;1.23$. Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating that Concor tablet is bioequivalent to Monocor tablet.

• 한국강구조학회 논문집
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• 제18권3호
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• pp.395-403
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• 2006

최근 건설되는 강교량은 지간의 장대화 및 교량으로서의 기능은 물론이고 외적 조형미, 유지관리, 공사기간과 수명주기 비용 등을고려한 구조적 단순함을 요한다. 이러한 요구를 충족시키기 위해 극후판이나 TMCP 강과 같은 고성능 강의 사용이 요구된다. TMCP (Thermo-Mechanical Control Proces)법에 의해 제조되는 TMCP 강은 탄소당량이 적고, 조직이 미세하며, 강도 및 인성이 좋다. 최근에는 인장강도 60MPa급의 고강도 TMCP 강인 SM570-TMC 강이 개발되어 토목구조물에 일부 적용되고 있으며, 점차 그 영역을 확장하려는 추세에 있다. 하지만 이러한 고강도 TMCP 강을 강구조물에 적용하기 위해서는 그 재료적 특성뿐만 아니라 용접 시 발생하는 접합부의 역학적 특징을 명확히 할 필요가 있다. 따라서 본 연구에서는 고온인장실험을 통해서 SM570-TMC 강의 고온시의 기 계적 특성을 조사하였고, 이를 잔류응력 특징을 명확히 하였다.

• 간호행정학회지
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• 제8권2호
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• pp.295-308
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• 2002

Purpose: The purpose of this quasi-experimental research is to develop the CP for primary THR patients and verify its effectiveness. Method: The CP is designed for both patients and medical employees to meet the 14-day-long hospitalization with an expert and clinical validity test, and the standardized orders are also created. 21 eligible subjects for the control group(with common care plan) and 27 subjects for the experimental group(with CP service) were assigned. Data were collected from questionnaires to evaluate patients' satisfaction level of nursing care and CP, investigation of physical complications, inspection of LOS(length of hospital stay) and hospital charges from April 2000 to February 2001 at K-hospital in Daegu. The collected data were analyzed by using the SAS program. Results: After implementation of CP, there was a statistically significant reduction in mean length of stay. The hospital charges have no considerable difference between two groups. Frequency of physical complications is reduced considerably. The experimental group scored much higher than the control group on the satisfaction level toward nursing care. And in the analysis of CP satisfaction questionnaires, many subjects have high satisfaction in items of 'I see the treatment process and hospital life', 'I feel that I am participating in my treatment process with health care staff'. The analysis of variances which cause a prolonged LOS supports that it's necessary to strengthen an evaluation of pre-operative outpatients' condition and link the home nursing care system in discharge for more shortening of LOS. Conclusion: The above results show that CP can have a positive impact on satisfaction level of inpatients with primary THR and the hospital.

• 한국해양공학회지
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• 제23권5호
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• pp.85-91
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• 2009

A stainless steel that contains aggressive negative ion was known to decrease the corrosion resistance. Stainless steel with super corrosion resistance was developed for improvement of corrosion resistance. Super duplex stainless steel is widely used under sever environment because of good mechanical properties and corrosion resistance. Also, Super duplex stainless steel has long life in severe environments by showing the enough strength and corrosion resistance. But duplex stainless steel is not stabilized compared to austenite stainless steel in corrosion resistance. In this study, corrosion characteristic were investigated to super duplex stainless steel with additive 0.2% nitrogen with $SiO_2$ thin films coated or no coated by sol-gel method in 3.5% NaCl. From test results, corrosion current density in the heat-treated specimen for ${\sigma}$ phase precipitation was higher than that of different heat-treated specimen. Also, $SiO_2$ colloidal-coated specimen had not occurred almost corrosion.

• 마이크로전자및패키징학회지
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• 제14권2호
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• pp.23-33
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• 2007

RoHS, WEEE 등에서의 각종 환경문제에 대한 제약으로 Pb의 사용에 대한 규제가 점차 증가 하고 있다. 따라서 무연 솔더에 대한 관심이 증폭되고 있으며, 마이크로 전자공학 산업에서 무연 솔더를 사용하기 위해서는 여러 가지 새로운 신뢰성 평가기준을 요구한다. 예를 들어 높은 온도공정을 만족하는 패키지, 새로운 솔더가 야기하는 복잡한 기계적 고장, 그리고 제품 수명을 최대한 유지시켜 줄 수 있는 무연 솔더 소재의 선택을 포함한다. 본 연구에서는 국내산 솔더바 소재를 사용하여 접합부의 기계적 특성 및 젖음성, 퍼짐성 등의 품질평가 방법을 해외규격과 비교하여 시험하고 새로운 평가기준을 찾고자 하였다. 젖음성 및 퍼짐성 시험 결과 Sn-0.7Cu 무연 솔더 소재는 평가기준을 충분히 만족하였다. 또한 이 소재를 사용한 솔더 접합부의 전단시험 결과, 열충격 및 고온방치 시험 후에도 솔더링 상태의 초기강도와 비교하여 접합부의 전단강도가 크게 저하하지 않은 상태에서 기준치를 크게 상회하였다.

• 임상간호연구
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• 제21권2호
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• pp.215-222
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• 2015

Purpose: For hemodialysis, a vascular access which can maintain a certain speed for a long time is required. The prevention of the vascular access dysfunction is very important to decrease morbidity and to improvethe quality of life of patients receiving hemodialysis It is reported that far infrared heat increases the blood flow by expanding capillaries and micro-arteriovenouses. This study aimed to evaluate the effect of far infrared heat therapy as a new nursing intervention for maintaining vascular access function and improving the blood flow of patients receiving hemodialysis. Methods: The quasi-experimental research of nonequivalent control group pre-post test design was carried out for 59 patients receiving hemodialysis 3 times per week at K medical center. A far infrared heat was applied to the experimental group for 3 months. Results: The arteriovenous fistula blood flow of the experimental group (far infrared heat therapy group) increased significantly when compared to the control group (p=.047). However, static intra-access pressure ratio(SIAPR)was not different statistically (p=.101). Conclusion: The far infrared therapy could be considered as nursing intervention of choice as it demonstrated increase in the arteriovenous fistula blood flow in the patients receiving hemodialysis.