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과학 학회 성립의 사적 고찰 - 영국의 과학 왕립 학회와 프랑스의 왕립 아카데미 창립을 중심으로 - (Historical Review in Foundation of London Loyal Society and France Loyal Academy)

  • 김동필
    • 한국과학교육학회지
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    • 제1권1호
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    • pp.29-34
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    • 1978
  • This study is searching for the Historical significance of Background in foundation of London Society and France Loyal Academy. These Academy foundation was contribu ted for establishing the Basis of Scientific theory, method and thought in late century.

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런던 St.Pancars Station & King's Cross Station 인접지역의 철도역사 기반 도시재생계획에 관한 연구 (A study on the Project Planning Method of Areas near St.Pancars Station & King's Cross Station in London)

  • 신예경
    • 예술인문사회 융합 멀티미디어 논문지
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    • 제6권10호
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    • pp.603-612
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    • 2016
  • 본 연구에서는 철도를 통해 유럽대륙으로부터 런던으로 들어오는 관문인 세인트 판크라스 역과 런던 내 인터시티 연결을 주도하는 킹스크로스 역의 개발 및 인접한 두 개의 역 사이에 위치하고 있는 Camden지구 King's Cross Central을 중심으로 추진된 도심재생 사례의 계획특성을 살펴보고, 이를 바탕으로 여기에서 추진된 도심재생의 계획의 방향, 세부전략을 알아보고자 하였다. 연구의 결과 킹스크로스역과 세인트판크라스 역, 그리고 그 인접에 위치한 배후지역으로서 King's Cross Central 지역은 오랜 기간 슬럼지역이었으나 서로 인접한 두 역이 각기 영국 및 런던의 철도 네트워크에서 유럽대륙간의 국제 고속 철도 그리고 런던 내 국내철도와의 연계라는 공통분모를 가지고 철도 교통의 잠재성을 기반으로 새롭게 재활성화 되었다. 여기에는 건물에 대한 물리적 현대화뿐만 아니라. 지상과 지하 그리고 각 지역을 지원하는 조밀한 철도 네트워크 구축과 연계교통의 체계화를 하되, 이는 동시에 환승에 용이한 보행 동선을 확보하고 시민의 공공성을 고려한 다각적인 용도의 각 시설물들을 계획, 배치하였음을 확인하였다.

Evaluation of the influence of creep and shrinkage determinants on column shortening in mid-rise buildings

  • B-Jahromi, Ali;Rotimi, Abdulazeez;Tovi, Shivan;Goodchild, Charles;Rizzuto, Joseph
    • Advances in concrete construction
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    • 제5권2호
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    • pp.155-171
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    • 2017
  • The phenomenon of concrete column shortening has been widely acknowledged since it first became apparent in the 1960s. Axial column shortening is due to the combined effect of elastic and inelastic deformations, shrinkage and creep. This study aims to investigate the effects of ambient temperature, relative humidity, cement hardening speed and aggregate type on concrete column shortening. The investigation was conducted using a column shortening prediction model which is underpinned by the Eurocode 2. Critical analysis and evaluation of the results showed that the concrete aggregate types used in the concrete have significant impact on column shortening. Generally, aggregates with higher moduli of elasticity hold the best results in terms of shortening. Cement type used is another significant factor, as using slow hardening cement gives better results compared to rapid hardening cement. This study also showed that environmental factors, namely, ambient temperature and relative humidity have less impact on column shortening.

Validity and Reliability of the Fagerstrom Test for Cigarette Dependence in a Sample of Arabic Speaking UK-Resident Yemeni Khat Chewers

  • Kassim, Saba;Salam, Mohamed;Croucher, Ray
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권4호
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    • pp.1285-1288
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    • 2012
  • Background: The Fagerstrom Test for Cigarette Dependence (FTCD) (formally FTND) is widely used for measuring physical dependence on nicotine. Objective: To explore the cross cultural validity and reliability of FTCD amongst Arabic speaker cigarette consumers who chew khat leaf, a stimulant green leaf. Methods: The psychometric properties of the FTCD were assessed in a subsample (91regular cigarette smokers) of purposively selected 204 UK-resident Yemeni khat chewers recruited during random visits to khat sale outlets. Data were collected via a structured face-to-face interview. Data analyses included descriptive tests and factor analysis. Results: Two factors were obtained by a principle axis factor analysis and these were termed as urgency of restoring the level of nicotine after abstinence during sleeping and maintaining the level of nicotine during waking. The internal reliability (Cronbach's alpha coefficient) of the whole FTCD is low (.68) as well as for the two subscales (.60) and (.62) respectively. Conclusion: The psychometric properties of the Arabic version of the FTCD scale in this sample of Yemeni khat chewers who smoked regularly confirmed what has been established in other cultural settings. The findings of this study have yet to be cross validated amongst other appropriately representative sample of Arabic speakers.

Assessment of London underground tube tunnels - investigation, monitoring and analysis

  • Wright, Peter
    • Smart Structures and Systems
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    • 제6권3호
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    • pp.239-262
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    • 2010
  • Tube Lines has carried out a "knowledge and investigation programme" on the deep tube tunnels comprising the Jubilee, Northern and Piccadilly lines, as required by the PPP contract with London Underground. Many of the tunnels have been in use for over 100 years, so this assessment was considered essential to the future safe functioning of the system. This programme has involved a number of generic investigations which guide the assessment methodology and the analysis of some 5,000 individual structures. A significant amount of investigation has been carried out, including ultrasonic thickness measurement, detection of brickwork laminations using radar, stress measurement using magnetic techniques, determination of soil parameters using CPT, pressuremeter and laboratory testing, installation of piezometers, material and tunnel segment testing, and trialling of remote photographic techniques for inspection of large tunnels and shafts. Vibrating wire, potentiometer, electro level, optical and fibre-optic monitoring has been used, and laser measurement and laser scanning has been employed to measure tunnel circularity. It is considered that there is scope for considerable improvements in non-destructive testing technology for structural assessment in particular, and some ideas are offered as a "wish-list". Assessment reports have now been produced for all assets forming Tube Lines' deep tube tunnel network. For assets which are non-compliant with London Underground standards, the risk to the operating railway has to be maintained as low as reasonably practicable (ALARP) using enhanced inspection and monitoring, or repair where required. Monitoring techniques have developed greatly during recent years and further advances will continue to support the economic whole life asset management of infrastructure networks.

Latent Transforming Growth Factor-beta1 Functionalised Electrospun Scaffolds Promote Human Cartilage Differentiation: Towards an Engineered Cartilage Construct

  • Lim, Erh-Hsuin;Sardinha, Jose Paulo;Myers, Simon;Stevens, Molly
    • Archives of Plastic Surgery
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    • 제40권6호
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    • pp.676-686
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    • 2013
  • Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed incorporating latent transforming growth factor-${\beta}$1 (LTGF) into an electrospun poly(L-lactide) scaffold. Methods The electrospun scaffold was surface modified with NH3 plasma and biofunctionalised with LTGF to produce both random and orientated biofunctionalised electrospun scaffolds. Scaffold surface chemical analysis and growth factor bioavailability assays were performed. In vitro biocompatibility and human nasal chondrocyte gene expression with these biofunctionalised electrospun scaffold templates were assessed. In vivo chondrogenic activity and chondrocyte gene expression were evaluated in athymic rats. Results Chemical analysis demonstrated that LTGF anchored to the scaffolds was available for enzymatic, chemical and cell activation. The biofunctionalised scaffolds were non-toxic. Gene expression suggested chondrocyte re-differentiation after 14 days in culture. By 6 weeks, the implanted biofunctionalised scaffolds had induced highly passaged chondrocytes to re-express Col2A1 and produce type II collagen. Conclusions We have demonstrated a proof of concept for cell-mediated activation of anchored growth factors using a novel biofunctionalised scaffold in cartilage engineering. This presents a platform for development of protein delivery systems and for tissue engineering.

The Exoscope versus operating microscope in microvascular surgery: A simulation non-inferiority trial

  • Pafitanis, Georgios;Hadjiandreou, Michalis;Alamri, Alexander;Uff, Christopher;Walsh, Daniel;Myers, Simon
    • Archives of Plastic Surgery
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    • 제47권3호
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    • pp.242-249
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    • 2020
  • Background The Exoscope is a novel high-definition digital camera system. There is limited evidence signifying the use of exoscopic devices in microsurgery. This trial objectively assesses the effects of the use of the Exoscope as an alternative to the standard operating microscope (OM) on the performance of experts in a simulated microvascular anastomosis. Methods Modus V Exoscope and OM were used by expert microsurgeons to perform standardized tasks. Hand-motion analyzer measured the total pathlength (TP), total movements (TM), total time (TT), and quality of end-product anastomosis. A clinical margin of TT was performed to prove non-inferiority. An expert performed consecutive microvascular anastomoses to provide the exoscopic learning curve until reached plateau in TT. Results Ten micro sutures and 10 anastomoses were performed. Analysis demonstrated statistically significant differences in performing micro sutures for TP, TM, and TT. There was statistical significance in TM and TT, however, marginal non-significant difference in TP regarding microvascular anastomoses performance. The intimal suture line analysis demonstrated no statistically significant differences. Non-inferiority results based on clinical inferiority margin (Δ) of TT=10 minutes demonstrated an absolute difference of 0.07 minutes between OM and Exoscope cohorts. A 51%, 58%, and 46% improvement or reduction was achieved in TT, TM, TP, respectively, during the exoscopic microvascular anastomosis learning curve. Conclusions This study demonstrated that experts' Exoscope anastomoses appear non-inferior to the OM anastomoses. Exoscopic microvascular anastomosis was more time consuming but end-product (patency) in not clinically inferior. Experts' "warm-up" learning curve is steep but swift and may prove to reach clinical equality.