• Journal of Institute of Control, Robotics and Systems
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• v.16 no.4
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• pp.313-318
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• 2010

This paper deals with the relationship between zeros and step response of the second and third order LTI (Linear Time Invariant) SISO (Single-Input and Single-Output) systems with complex poles. Although it has been known that the maximum number of local extrema is less than the number of zeros in the system with only real poles[8], some cases with complex poles are shown in this paper to have many local extrema. This paper proposes monotone nondecreasing conditions and describes the relationship between the transient response and the number of local extrema in step response with each region of zeros.

• Smart Structures and Systems
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• v.8 no.2
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• pp.157-172
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• 2011

A new method for both local damage(s) identification and input excitation force identification of beam structures is presented using the dynamic response sensitivity-based finite element model updating method. The state-space approach is used to calculate both the structural dynamic responses and the responses sensitivities with respect to structural physical parameters such as elemental flexural rigidity and with respect to the force parameters as well. The sensitivities of displacement and acceleration responses with respect to structural physical parameters are calculated in time domain and compared to those by using Newmark method in the forward analysis. In the inverse analysis, both the input excitation force and the local damage are identified from only several acceleration measurements. Local damages and the input excitation force are identified in a gradient-based model updating method based on dynamic response sensitivity. Both computation simulations and the laboratory work illustrate the effectiveness and robustness of the proposed method.

• Radiation Oncology Journal
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• v.30 no.4
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• pp.153-157
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• 2012

Purpose: There has been no definite consensus on standard treatment, either local or systemic, for the Kaposi's sarcoma (KS). Radiotherapy (RT) can be a good local therapeutic choice especially in non-AIDS associated KS (NAKS) for its indolent behavior. Materials and Methods: Medical records of 17 KS patients treated with RT at the Seoul National University Hospital from February 1998 to January 2012 were retrospectively reviewed. One human immunodeficiency virus (HIV)+ patient with 3 lesions was excluded. The total number of the lesion was 23 among the 16 patients. The median follow-up period was 27.9 months. Correlation between response and variables was analyzed using the logistic regression model. Median age of the patients was 75 years. All the 23 lesions were located at the extremities. Fourteen (61%) of those had pain or local swelling as the initial presentation. Ten patients had possible causes of immunodeficiency and were regarded as iatrogenic, and other 6 were classic KS. Median dose of RT was 36 Gy. Results: No KS-related death was observed. Excluding 2 with short-term follow-up only, complete response and partial response were obtained in 2 (9%) and 19 (73%) lesions, respectively. Of those, 3 lesions underwent local progression. Six had out-of-field recurrence after RT. Symptom improvement was achieved in 13 (93%) of 14 patients. Grade 2 skin toxicities were found in 9 lesions but all got improvement after treatment. When divided into responsive and progressive group, free from progression was not related to any of the possible variables. Conclusion: RT is effective in local control of NAKS resulting great response rate.

• Earthquakes and Structures
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• v.15 no.1
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• pp.67-79
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• 2018

Malaysia and Singapore have adopted Eurocode 8 (EC8) for the seismic design of building structures. The authors studied the seismic hazard modelling of the region surrounding Malaysia and Singapore for a long time and have been key contributors to the drafting of the Malaysia National Annex (NA). The purpose of this paper is to explain the principles underlying the derivation of the elastic response spectrum model for Malaysia (Peninsular Malaysia, Sarawak and Sabah). The current EC8 NA for Singapore is primarily intended to address the distant hazards from Sumatra and is not intended to provide coverage for potential local intraplate hazards. Hence, this paper recommends a reconciled elastic response spectrum for Singapore, aiming to achieve a more robust level of safety. The topics covered include the modelling of distant interplate earthquakes generated offshore and local earthquakes in an intraplate tectonic setting, decisions on zoning, modelling of earthquake recurrences, ground motion and response spectrum. Alternative expression for response spectrum on rock, strictly based on the rigid framework of EC8 is discussed.

• Korean Journal of Head & Neck Oncology
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• v.17 no.2
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• pp.179-184
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• 2001

Objective: The role of chemotherapy in locally advanced head and neck cancer has been established in nasopharynx and larynx as definitive therapy and organ preserving therapy, respectively. Oral cavity cancers are relatively uncommon and local recurrence is the main cause of treatment failure. We planned this retrospective study to evaluate the role of neoadjuvant chemotherapy in locally advanced oral cavity cancer patients. Materials and Methods: From 1988 March to 2001 February, locally advanced, previously untreated oral cavity cancer patients who received neoadjuvant chemotherapy were examined. Chemotherapy had been done in the following patients: Histologically proven squamous cell or poorly differentiated carcinoma, stage 3 or 4, and performance state 0-2 patients. Chemotherapy regimen consisted of cisplatin and infusional 5-fluorouracil. Response was evaluated after 2 cycles and in case of no response, definitive local therapy was done; otherwise 3 cycles was done before local treatment. Results: 48 patients were treated and 47 patients were evaluable for responses. Complete response rate was 6.4%(3/47) and partial response 80.0%(38/47), scoring overall response rate of 87.2%. Median time to progression was 27.0 months (95% CI : 0-58months) and overall 5 year survival was 54.8%. 5-year disease-free survival in the patients in remission after local treatment was 51.9%. In multivariate analysis, contributing factor to the survival were response to neoadjuvant chemotherapy and local treatment modalities. Extensive surgery was done in 10 patients and 25 patents (52.1%) was followed up with preserved function. With median follow-up of 57.0 months, 19 recurrences were detected, most of which were local or regional type. Conclusion: Neoadjuvant chemotherapy followed by local treatment in oral cavity cancer showed high response rate and was thought to be effective therapeutic approach especially in view of organ preservation.

• Journal of Navigation and Port Research
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• v.47 no.3
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• pp.174-181
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• 2023

Five local governments along the Korea-Japan Sea (Jeju, Jeonnam, Gyeongnam, Busan, Ulsan) operate a joint countermeasure committee regarding the marine discharge of contaminated water from the Fukushima nuclear power plant by Japan's Tokyo Electric Power Plant. This study compared and analyzed citizen surveys, response strategies, and detailed action plans conducted by the Jeju Research Institute, Busan Research Institute, and Ulsan Research Institute as part of a study on countermeasures for the marine discharge of contaminated water from the Fukushima nuclear power plant in Japan. The purpose was to present basic data for the preparation of effective measures. As a result of the perception survey, all citizens of local governments showed a strong negative perception of marine discharge regardless of scientific research results, and it is expected that future fisheries and tourism industries will suffer great damage. In response strategies for each local government, building a control tower was found to be the most urgent task common to all local governments. It is judged that this is because it is necessary to break away from the organization-centered system and to respond to the function-centered system for effective response. In terms of response methods, while Jeju and Busan established response plans for each sector, Ulsan City focused on practical responses with step-by-step response measures according to the release time. In terms of content, the establishment of a marine product radiation inspection system and publicity to relieve public anxiety were important. As the marine discharge of contaminated water from the Fukushima nuclear power plant is scheduled to continue until 2030, strengthening the network for sharing research results and achievements among local government research institutes was deemed necessary.

• Journal of Korean Society of Disaster and Security
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• v.5 no.1
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• pp.37-42
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• 2012

Local governments need to be prepared for emergency response in order to minimize damages caused by disasters, such as typhoon and chemical incidents. In this study, we have researched and analyzed current emergency preparedness status of Korea's local governments by studying laws and policies, and interviewing emergency managers. We have introduced policies to enhance emergency preparedness capabilities of United States' local governments. These policies could be useful for Korean government in developing policies to build up emergency response capabilities of Korea's local governments.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2011.10a
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• pp.257-261
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• 2011

The failures of local structure of marine medium-speed diesel engine occurred in durability test. The vibration response of the whole engine was in an acceptance level, but the local structures were broken. ODS test and vibration measurement were carried out in order to investigate the root cause of durability problem. These tests revealed that the root cause of failures was excessive vibration by $4.5^{th}$ resonance between engine body and local structure. The best solution to reduce the vibration response is to change the type of mount. After a rigid mount was replaced by a flexible mount, maximum vibration level dropped to 72%.

• Earthquakes and Structures
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• v.17 no.6
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• pp.557-566
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• 2019

The evaluation of the seismic hazard for a given site is to estimate the seismic ground motion at the surface. This is the result of the combination of the action of the seismic source, which generates seismic waves, the propagation of these waves between the source and the site, and site local conditions. The aim of this work is to evaluate the sensitivity of dynamic response of extended structures to spatial variable ground motions (SVGM). All factors of spatial variability of ground motion are considered, especially local site effect. In this paper, a method is presented to simulate spatially varying earthquake ground motions. The scheme for generating spatially varying ground motions is established for spatial locations on the ground surface with varying site conditions. In this proposed method, two steps are necessary. Firstly, the base rock motions are assumed to have the same intensity and are modelled with a filtered Tajimi-Kanai power spectral density function. An empirical coherency loss model is used to define spatial variable seismic ground motions at the base rock. In the second step, power spectral density function of ground motion on surface is derived by considering site amplification effect based on the one dimensional seismic wave propagation theory. Several dynamics analysis of a curved viaduct to various cases of spatially varying seismic ground motions are performed. For comparison, responses to uniform ground motion, to spatial ground motions without considering local site effect, to spatial ground motions with considering coherency loss, phase delay and local site effects are also calculated. The results showed that the generated seismic signals are strongly conditioned by the local site effect. In the same sense, the dynamic response of the viaduct is very sensitive of the variation of local geological conditions of the site. The effect of neglecting local site effect in dynamic analysis gives rise to a significant underestimation of the seismic demand of the structure.

• Structural Engineering and Mechanics
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• v.60 no.3
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• pp.433-453
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• 2016

During earthquake, the motion of ground is affected significantly by source characteristics, source-to-site path properties and local site conditions. Due to the influence of local soil conditions different places experience distinctive amplitude of surface ground motion. Ground response analysis of a specific site utilizing the borehole information at different locations is done in present study. The ground motion with the highest peak ground acceleration for this site obtained from the ground response analysis is used in finite element soil-structure interaction analysis of multi-storey shear wall buildings with various positions of shear walls. The variation in seismic response of buildings and advantageous position of shear wall are determined. The study reveals that providing shear wall at the core of buildings at the specific site is advantageous among all shear wall configurations considered.