• Radiation Oncology Journal
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• 제2권2호
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• pp.245-252
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• 1984

The record of radiation therapy cases during a five year period at the University of Michigan Hospitals has been analyzed. Of a total of 73 adenocarcinoma of prostate, the majority belonged to Stage B and C which represented 49 and 20 cases, respectively. The mortality rate after irradiation was clearly related to the tumor stage. Local irradiation resulted in $88\%$ of the local control of well·differentiated adenocarcinomas. Stage C cases had $50\%$ mortality, whereas that of Stage B patients was $14\%$. Results of this study are in general agreement with previous data in terms of the local disease control after irradiation and provide a basis for conservative radiotherapy regimen as an approach in the treatment of localized prostatic carcinomas.

• 제어로봇시스템학회논문지
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• 제6권4호
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• pp.313-319
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• 2000

As the interest of flexible manufacturing systems and computer integrated manufacturing systems increase, the distribution of centralized control systems using industrial control networks is getting more attention. In this paper, we investigate the rate-based traffic control of industrial control networks to improve the performance regarding the throughput, fairness, and error rates. Especially, we consider the protocol of Lon-$Works^{(TM)}$ which consists of all OSI 7-layers and supports various communication media at a low cost. Basically, the proposed rate-based traffic control system is closed loop by utilizing the feedback channel errors, which shows improved performance when compared with other industrial control networks commonly operated in open loop. To this end, an additional network node called monitoring node is introduced to check the channel status without increasing the channel load. The Proposed control loop is in effect whenever the feedback channel error becomes greater than an admittable value. We demonstrate the improved performance of the controlled network system in view of throughput and fairness measures by implementing the lab-scale network system based on LonWorks and through the experimentation upon it.

• Radiation Oncology Journal
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• 제9권2호
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• pp.325-331
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• 1991

1979년부터 1988년까지 서울대학교병원 치료방사선과에서 방사선 치료를 받았던 Wilms씨 종양환자 28명의 치료성적을 분석하였다. 평균 추적관찰기간은 40개월이었다. 3년 국소 치유율 및 생존율은 각각 78.1$\%$와 67.4$\%$이었다. 연령에 따른 국소치유율의 차이는 없었다. Favorable histology 와 Unfavorable histology 유형의 국소치유율은 각각 83.3$\%$와 62.5$\%$이었다. Favorable histology유형의 II기와 III기 종양의 국소치유율 간에는 차이가 없었다($83.3\%\;vs100.0\%$). Unfavorable histology유형의 I/II기와 III기 종양의 국소치유율 간에는 유의한 차이가 있었다($83.3\%:0\%$). 임파절 침윤이 확인된 경우에서의 국소치유율은 불량하였다($50.0\%\;vs\;87.5\%$). 방사선치료를 수술후 10일 이후에 개시한 경우에서의 국소치유율과 수술 후 9일 이내에 개시한 경우에서의 국소치유율 간에는 유의한 차이가 있었다(p<0.05) . 따라서 방사선치료는 국소치유율을 향상시키는데 유용하였으나 수술적 절제가 불가능한 종양에 대하여는 치료방법의 강화가 필요하다고 판단된다.

• Radiation Oncology Journal
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• 제30권4호
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• pp.153-157
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• 2012

Purpose: There has been no definite consensus on standard treatment, either local or systemic, for the Kaposi's sarcoma (KS). Radiotherapy (RT) can be a good local therapeutic choice especially in non-AIDS associated KS (NAKS) for its indolent behavior. Materials and Methods: Medical records of 17 KS patients treated with RT at the Seoul National University Hospital from February 1998 to January 2012 were retrospectively reviewed. One human immunodeficiency virus (HIV)+ patient with 3 lesions was excluded. The total number of the lesion was 23 among the 16 patients. The median follow-up period was 27.9 months. Correlation between response and variables was analyzed using the logistic regression model. Median age of the patients was 75 years. All the 23 lesions were located at the extremities. Fourteen (61%) of those had pain or local swelling as the initial presentation. Ten patients had possible causes of immunodeficiency and were regarded as iatrogenic, and other 6 were classic KS. Median dose of RT was 36 Gy. Results: No KS-related death was observed. Excluding 2 with short-term follow-up only, complete response and partial response were obtained in 2 (9%) and 19 (73%) lesions, respectively. Of those, 3 lesions underwent local progression. Six had out-of-field recurrence after RT. Symptom improvement was achieved in 13 (93%) of 14 patients. Grade 2 skin toxicities were found in 9 lesions but all got improvement after treatment. When divided into responsive and progressive group, free from progression was not related to any of the possible variables. Conclusion: RT is effective in local control of NAKS resulting great response rate.

• 한국통신학회논문지
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• 제32권5B호
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• pp.295-303
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• 2007

An algorithm is proposed to seek a local optimal solution of the network utility maximization problem in a wireless mesh network, where the architecture being considered is an infrastructure/backbone wireless mesh network. The objective is to achieve proportional fairness amongst the end-to-end flows in wireless mesh networks. In order to establish the communication constraints of the flow rates in the network utility maximization problem, we have presented necessary and sufficient conditions for the achievability of the flow rates. Since wireless mesh networks are generally considered as a type of ad hoc networks, similarly as in wireless multi-hop network, the network utility maximization problem in wireless mesh network is a nonlinear nonconvex programming problem. Besides, the gateway/bridge functionalities in mesh routers enable the integration of wireless mesh networks with various existing wireless networks. Thus, the rate optimization problem in wireless mesh networks is more complex than in wireless multi-hop networks.

• Radiation Oncology Journal
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• 제34권3호
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• pp.216-222
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• 2016

Purpose: To evaluate the benefit of adjuvant radiation therapy (RT) for retroperitoneal liposarcoma (RPLS) following gross tumor removal. Materials and Methods: We reviewed 77 patients with primary RPLS surgically treated between January 2000 and December 2013. Cases with gross residual disease were excluded. Tumor grade was evaluated according to the French Federation of Cancer Centers Sarcoma Group (FNCLCC) system. Adjuvant RT was delivered to 32 patients (42%) using external beam RT alone. Median follow-up time was 36 months (range, 5 to 169). Results: Among 77 patients, 33 (43%) presented with well-differentiated, 31 (40%) with de-differentiated, 8 (10%) with myxoid/round and 4 (5%) with pleomorphic morphology. The RT group included less well-differentiated subtype than surgery group (28% vs. 53%). During follow up, 34 patients (44%) showed local recurrence. Local recurrence rate was lower in the RT group (38%) compared to the surgery group (49%). The 3-year local control rate (LC) was 55.6%, and the 3-year overall survival (OS) was 82.1%. Tumor histology and FNCLCC grade were significantly associated with local recurrence. There was no statistical significance of adding adjuvant RT in LC (p = 0.312). However, patients with tumor histology other than well-differentiated subtype showed marginally decreased local recurrence rate after adjuvant RT (3-year LC, RT 43.9% vs. no RT 35.3%; p = 0.087). Conclusion: RPLS patients receiving RT experienced less local recurrence. We suggest that the addition of adjuvant RT may be related to improvement of LCs, especially in patients with non-favorable histologic subtypes.

• 한국정밀공학회지
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• 제14권1호
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• pp.101-107
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• 1997

Recently, as the raw water quality becomes to be polluted and the seasonal and local variation of water quality becomes to be severe, an exact control of coagulant dosing have been required in the water treat- ment plant. The amounts of coagulant is related to the raw water quality such as turbidity, alkalinity, water temperature, pH and edectrical conductivity. However the process of chemical reaction has not been clarified so far, so the dosing rate has been decided by jar-test, which is taken one or two hours. For the sake of this coagulant dosing control, fuzzy neural network to fuse fuzzy logic and neural network was proposed, and the scheme was applied to automatic determination of coagulant dosing rate. This controller can automatically identify the if-then rules and tune the membership functions by utilizing expert's cintrol data. It is shown that determination of coagulant dosing rate according to real time sensing of water quality is very effect.

• 설비공학논문집
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• 제13권10호
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• pp.947-959
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• 2001

We propose a control scheme to control the indoor zone temperature via variable air volume (VAV) unit. To control the room temperature, state space model of the conditioned zone which is partitioned into nine artificial sectional regions is derived. The nonlinearity of the damper motion and actuator are considered for the practical use in the state space system description. The temperature control of the room temperature is performed by manipulating the degree of openness of the damper in relation to the local room temperature and the supplied air flow rate. In general, since a local temperature in the conditioned zone is measured, it is required to estimate the temperature values in each regions for the precise temperature control. We thus design a state observer to estimate the regional temperature, and use these values in the controller. The overall control system consists of the state observer based state feedback with the integral control. We compared the control results of the proposed scheme with those of cascade proportional and integral (PI) control, and showed that the scheme achieved precise control of the conditioned system.

• Journal of Korean Neurosurgical Society
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• 제50권3호
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• pp.179-184
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• 2011

Objective : The aim of this study is to evaluate the therapeutic effects of gamma knife radiosurgery (GKRS) in patients with multiple brain metastases and to investigate prognostic factors related to treatment outcome. Methods : We retrospectively reviewed clinico-radiological and dosimetric data of 36 patients with 4-14 brain metastases who underwent GKRS for 264 lesions between August 2008 and April 2011. The most common primary tumor site was the lung (n=22), followed by breast (n=7). At GKRS, the median Karnofsky performance scale score was 90 and the mean tumor volume was 1.2 cc (0.002-12.6). The mean prescription dose of 17.8 Gy was delivered to the mean 61.1% isodose line. Among 264 metastases, 175 lesions were assessed for treatment response by at least one imaging follow-up. Results : The overall median survival after GKRS was $9.1{\pm}1.7$ months. Among various factors, primary tumor control was a significant prognostic factor ($11.1{\pm}$1.3 months vs. $3.3{\pm}2.4$ months, p=0.031). The calculated local tumor control rate at 6 and 9 months after GKRS were 87.9% and 84.2%, respectively. Paddick's conformity index (>0.75) was significantly related to local tumor control. The actuarial peritumoral edema reduction rate was 22.4% at 6 months. Conclusion : According to our results, GKRS can provide beneficial effect for the patients with multiple (4 or more) brain metastases, when systemic cancer is controlled. And, careful dosimetry is essential for local tumor control. Therefore, GKRS can be considered as one of the treatment modalities for multiple brain metastase.

• 한국정보처리학회논문지
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• 제5권6호
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• pp.1610-1619
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• 1998

매우 버스티한 특성을 갖는 데이터 트래픽을 지원하는 ABR (Available Bit Rate) 서비스 클래스는 피드백을 이용하여 트래픽을 제어한다. 이에 관한 연구는 점-대-점 연결에 적용하기 위한 것으로 시작되어 최근에는 멀티캐스트 서비스를 요구하는 트래픽 전송이 증가함에 따라 점-대-다중점에 적용하는 연구로 확장되고 있다. 그런데 피드백에 의하여 트래픽을 제어하는 경우 전파지연이 클수록 제어의 효율성이 떨어지게 된다. 특히 멀티캐스트의 경우에는 원거리 수신원은 근거리 수신원에 비하여 피드백의 적시성이 더 떨어져 경로 상황 및 수신원 능력이 동일함에도 불구하고 더 낮은 서비스를 받는 불공정성이 발생할 수 있다. 따라서 멀티캐스트의 경우에는 전파지연으로 인한 피드백 부적시성을 수정하는 것이 더 중요하다. 본 논문은 EPRCA (Enhanced Proportional Rate Control Algorithm)에 의하여 ABR 멀티캐스트 트래픽을 제어하는 스위치들이 자신의 능력이 허용하는 경우 동적인 셀 스케줄링을 이용하여 하단의 폭주에 일시적으로 반응하는 방식을 제안함으로써 원거리 수신원에 대한 제어를 효율적으로 해 줄 수 있는 스위치 동작에 대하여 살펴보았다. 제안한 스위치는 VC (Vitrual Circuit)마다 피드백되는 역방향 RM (Resource Management) 셀에 의하여 동적인 셀 스케줄링을 하므로VC마다 버퍼를 두는 구현상의 복잡성이 있으며, 버퍼 점유율이 높아지는 오버헤드가 있다. 시뮬레이션을 통하여 제안한 스위치 동작을 멀티캐스트 연결에 적용하여 본 결과원거리와 근거리 모든 수신원에서의 셀 손실율이 낮아질 뿐 아니라 두 수신원간의 셀 손실율의 차를 감소시킬 수 있음을 볼 수 있었다.