• Radiation Oncology Journal
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• 제2권2호
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• pp.245-252
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• 1984

The record of radiation therapy cases during a five year period at the University of Michigan Hospitals has been analyzed. Of a total of 73 adenocarcinoma of prostate, the majority belonged to Stage B and C which represented 49 and 20 cases, respectively. The mortality rate after irradiation was clearly related to the tumor stage. Local irradiation resulted in $88\%$ of the local control of well·differentiated adenocarcinomas. Stage C cases had $50\%$ mortality, whereas that of Stage B patients was $14\%$. Results of this study are in general agreement with previous data in terms of the local disease control after irradiation and provide a basis for conservative radiotherapy regimen as an approach in the treatment of localized prostatic carcinomas.

• Journal of Institute of Control, Robotics and Systems
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• 제6권4호
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• pp.313-319
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• 2000

As the interest of flexible manufacturing systems and computer integrated manufacturing systems increase, the distribution of centralized control systems using industrial control networks is getting more attention. In this paper, we investigate the rate-based traffic control of industrial control networks to improve the performance regarding the throughput, fairness, and error rates. Especially, we consider the protocol of Lon-$Works^{(TM)}$ which consists of all OSI 7-layers and supports various communication media at a low cost. Basically, the proposed rate-based traffic control system is closed loop by utilizing the feedback channel errors, which shows improved performance when compared with other industrial control networks commonly operated in open loop. To this end, an additional network node called monitoring node is introduced to check the channel status without increasing the channel load. The Proposed control loop is in effect whenever the feedback channel error becomes greater than an admittable value. We demonstrate the improved performance of the controlled network system in view of throughput and fairness measures by implementing the lab-scale network system based on LonWorks and through the experimentation upon it.

• Radiation Oncology Journal
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• 제9권2호
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• pp.325-331
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• 1991

Treatment results of 28 patients with Wilms' tumor who received radiation therapy at the Department of Therapeutic Radiology, Seoul National University Hospital from 1979 to 1988 were analyzed. The median follow-up period for the survivors was 40 months. The local control and overall survival rate at 3 years were 78.1$\%$ and 67.4$\%$, respectively. The local control was not affected by age. The local control rates for favorable histology (FH) and unfavorable histology (UH) were 83.3$\%$ and 62.5$\%$, respectively. In FH, the local control rates of stage II and III were not different ($83.3\%\;vs\;100.0\%$). In UH, the control rates of stage I/II and stage III were 83.3$\%$ and 0$\%$, respectively. Poor local control was correlated with involvement of lymph node ($50.0\%\;vs\;87.5\%$). Radiotherapy delayed 10 or more days after operation resulted in poorer local control than that without delay (p<0.05). Thus radiotherapy contributed to reduction of local recurrence in patients with high risk factor without increased severe complication. It is suggested that bulky unresectable mass might need a more intensified treatment.

• Radiation Oncology Journal
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• 제30권4호
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• pp.153-157
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• 2012

Purpose: There has been no definite consensus on standard treatment, either local or systemic, for the Kaposi's sarcoma (KS). Radiotherapy (RT) can be a good local therapeutic choice especially in non-AIDS associated KS (NAKS) for its indolent behavior. Materials and Methods: Medical records of 17 KS patients treated with RT at the Seoul National University Hospital from February 1998 to January 2012 were retrospectively reviewed. One human immunodeficiency virus (HIV)+ patient with 3 lesions was excluded. The total number of the lesion was 23 among the 16 patients. The median follow-up period was 27.9 months. Correlation between response and variables was analyzed using the logistic regression model. Median age of the patients was 75 years. All the 23 lesions were located at the extremities. Fourteen (61%) of those had pain or local swelling as the initial presentation. Ten patients had possible causes of immunodeficiency and were regarded as iatrogenic, and other 6 were classic KS. Median dose of RT was 36 Gy. Results: No KS-related death was observed. Excluding 2 with short-term follow-up only, complete response and partial response were obtained in 2 (9%) and 19 (73%) lesions, respectively. Of those, 3 lesions underwent local progression. Six had out-of-field recurrence after RT. Symptom improvement was achieved in 13 (93%) of 14 patients. Grade 2 skin toxicities were found in 9 lesions but all got improvement after treatment. When divided into responsive and progressive group, free from progression was not related to any of the possible variables. Conclusion: RT is effective in local control of NAKS resulting great response rate.

• The Journal of Korean Institute of Communications and Information Sciences
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• 제32권5B호
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• pp.295-303
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• 2007

An algorithm is proposed to seek a local optimal solution of the network utility maximization problem in a wireless mesh network, where the architecture being considered is an infrastructure/backbone wireless mesh network. The objective is to achieve proportional fairness amongst the end-to-end flows in wireless mesh networks. In order to establish the communication constraints of the flow rates in the network utility maximization problem, we have presented necessary and sufficient conditions for the achievability of the flow rates. Since wireless mesh networks are generally considered as a type of ad hoc networks, similarly as in wireless multi-hop network, the network utility maximization problem in wireless mesh network is a nonlinear nonconvex programming problem. Besides, the gateway/bridge functionalities in mesh routers enable the integration of wireless mesh networks with various existing wireless networks. Thus, the rate optimization problem in wireless mesh networks is more complex than in wireless multi-hop networks.

• Radiation Oncology Journal
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• 제34권3호
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• pp.216-222
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• 2016

Purpose: To evaluate the benefit of adjuvant radiation therapy (RT) for retroperitoneal liposarcoma (RPLS) following gross tumor removal. Materials and Methods: We reviewed 77 patients with primary RPLS surgically treated between January 2000 and December 2013. Cases with gross residual disease were excluded. Tumor grade was evaluated according to the French Federation of Cancer Centers Sarcoma Group (FNCLCC) system. Adjuvant RT was delivered to 32 patients (42%) using external beam RT alone. Median follow-up time was 36 months (range, 5 to 169). Results: Among 77 patients, 33 (43%) presented with well-differentiated, 31 (40%) with de-differentiated, 8 (10%) with myxoid/round and 4 (5%) with pleomorphic morphology. The RT group included less well-differentiated subtype than surgery group (28% vs. 53%). During follow up, 34 patients (44%) showed local recurrence. Local recurrence rate was lower in the RT group (38%) compared to the surgery group (49%). The 3-year local control rate (LC) was 55.6%, and the 3-year overall survival (OS) was 82.1%. Tumor histology and FNCLCC grade were significantly associated with local recurrence. There was no statistical significance of adding adjuvant RT in LC (p = 0.312). However, patients with tumor histology other than well-differentiated subtype showed marginally decreased local recurrence rate after adjuvant RT (3-year LC, RT 43.9% vs. no RT 35.3%; p = 0.087). Conclusion: RPLS patients receiving RT experienced less local recurrence. We suggest that the addition of adjuvant RT may be related to improvement of LCs, especially in patients with non-favorable histologic subtypes.

• Journal of the Korean Society for Precision Engineering
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• 제14권1호
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• pp.101-107
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• 1997

Recently, as the raw water quality becomes to be polluted and the seasonal and local variation of water quality becomes to be severe, an exact control of coagulant dosing have been required in the water treat- ment plant. The amounts of coagulant is related to the raw water quality such as turbidity, alkalinity, water temperature, pH and edectrical conductivity. However the process of chemical reaction has not been clarified so far, so the dosing rate has been decided by jar-test, which is taken one or two hours. For the sake of this coagulant dosing control, fuzzy neural network to fuse fuzzy logic and neural network was proposed, and the scheme was applied to automatic determination of coagulant dosing rate. This controller can automatically identify the if-then rules and tune the membership functions by utilizing expert's cintrol data. It is shown that determination of coagulant dosing rate according to real time sensing of water quality is very effect.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• 제13권10호
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• pp.947-959
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• 2001

We propose a control scheme to control the indoor zone temperature via variable air volume (VAV) unit. To control the room temperature, state space model of the conditioned zone which is partitioned into nine artificial sectional regions is derived. The nonlinearity of the damper motion and actuator are considered for the practical use in the state space system description. The temperature control of the room temperature is performed by manipulating the degree of openness of the damper in relation to the local room temperature and the supplied air flow rate. In general, since a local temperature in the conditioned zone is measured, it is required to estimate the temperature values in each regions for the precise temperature control. We thus design a state observer to estimate the regional temperature, and use these values in the controller. The overall control system consists of the state observer based state feedback with the integral control. We compared the control results of the proposed scheme with those of cascade proportional and integral (PI) control, and showed that the scheme achieved precise control of the conditioned system.

• Journal of Korean Neurosurgical Society
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• 제50권3호
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• pp.179-184
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• 2011

Objective : The aim of this study is to evaluate the therapeutic effects of gamma knife radiosurgery (GKRS) in patients with multiple brain metastases and to investigate prognostic factors related to treatment outcome. Methods : We retrospectively reviewed clinico-radiological and dosimetric data of 36 patients with 4-14 brain metastases who underwent GKRS for 264 lesions between August 2008 and April 2011. The most common primary tumor site was the lung (n=22), followed by breast (n=7). At GKRS, the median Karnofsky performance scale score was 90 and the mean tumor volume was 1.2 cc (0.002-12.6). The mean prescription dose of 17.8 Gy was delivered to the mean 61.1% isodose line. Among 264 metastases, 175 lesions were assessed for treatment response by at least one imaging follow-up. Results : The overall median survival after GKRS was $9.1{\pm}1.7$ months. Among various factors, primary tumor control was a significant prognostic factor ($11.1{\pm}$1.3 months vs. $3.3{\pm}2.4$ months, p=0.031). The calculated local tumor control rate at 6 and 9 months after GKRS were 87.9% and 84.2%, respectively. Paddick's conformity index (>0.75) was significantly related to local tumor control. The actuarial peritumoral edema reduction rate was 22.4% at 6 months. Conclusion : According to our results, GKRS can provide beneficial effect for the patients with multiple (4 or more) brain metastases, when systemic cancer is controlled. And, careful dosimetry is essential for local tumor control. Therefore, GKRS can be considered as one of the treatment modalities for multiple brain metastase.

• The Transactions of the Korea Information Processing Society
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• 제5권6호
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• pp.1610-1619
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• 1998

The ABR service class provides feedback based traffic control to transport bursty data traffic efficiently. Feedback based congestion control has first been studied to be applied to unicast connections. Recently. several congestion control algorithms for multicast connections have also been proposed as the number of ABR applications requiring multicast increases. With feedback based congestion control, the effectiveness of a traffic control scheme diminishes as propagation delay increases. Especially for a multicast connection, a remote destination may suffer unfair service compared to a local destination due to the delayed feedback. Amelioration of the disadvantages caused by feedback delay is therefore more important for remote destinations in multicast connections. This paper proposes a new switch behavior to provide effective feedback based mathc control for rentoh destinations. The proposed switches adjust the service rate dynamically in accordance woth the state of the downstream, that is, the congestion of the destinaion is immediately controlled by the nearest apstream switch before the source to ramp down the transmission rate of the connection. The proposed switch has an implementation overhead to have a separate buffer for each VC to adjust the service rate in accordance with a backward Rm cell of each VC. The buffer requirement id also increased at intermediate switches. Simulation results show that the proposed switch reduces the cell loss rate in both the local and the remote destinations and slso amelioratd the between the two destinations.