• 한국가금학회:학술대회논문집
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• 한국가금학회 2005년도 제22차 정기총회 및 학술발표회
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• pp.31-43
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• 2005

Isoflavones are naturally occurring plant chemicals belonging to the 'phytoestrogen' class. The isoflavones are strikingly similar in chemical structure to natural estrogens. The phenolic ring is a key structural element of most compounds that bind to estrogen receptors. Dietary components that recently have received attention for their action as phytoestrogens are soy isoflavones. Soy products are the most significant dietary sources of isoflavones. Recently It is concerned clinical nutrition of isoflavone that is driven by reason of alternative sources of exogenous estrogen are constantly being needed. Estrogen therapy after the menopause offers protection from cardiovascular disease, reduces the extent of osteoporosis and relieves menopausal symptoms. Exogenous estrogen treatment is a fear of possible increased risk of developing breast cancer and because of side effects. Daily intake of soybean or soy food can affirmative effect to disease occurrence, that is based on mechanical investigation, experimental results of animals and human. Research into isoflavone is going on various field to relieve hormone - dependent disease such as cancer, menopausal symptom, cardiovascular disease and osteoporosis. Isoflavone is plenty in soybean meal, soy by-product, but only limited information is available on isoflavone efficacy into animal husbandry. Thus we conducted three experiments to investigate the effects of dietary isoflavone on productivities, antioxidative responses and bone metabolism in poultry. Dietary supplementation of isoflavone resulted in preventing the lipid oxidation of plasma and egg yolk. Dietary isoflavone improved bone development in egg-type growing chicks and broilers in terms of tibial strength. It was suggested that the proper use of feed additives such as isoflavone might provide means of improving antioxidative effect, skeletal strength, egg and eggshell quality.

• 한국식품영양학회지
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• 제29권1호
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• pp.19-26
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• 2016

Mulberry (oddi) is one of the most popular functional foods with many physiological components. This study investigated and compared the nutritional compositions and physiological activities of four mulberry fruits from Morus albo L. including Cheongilppong, Iksuppong, Suwonppong and Cheongsuppong (a new cultivar from Chungcheongbuk-do). To analyze the nutrient contents, mulberry fruits were freeze-dried. The results showed that the proximate compositions of the four mulberry cultivars ranged from 9.61~14.11% for moisture, 8.28~11.90% for crude protein, 3.70~4.86% for crude ash, 4.28~5.54% for crude lipid and 7.46~10.78% for crude fiber. The above proximate contents of mulberry cultivars were not significantly different. However, Cheongsuppong had the highest content of reducing sugar, 74.7%. Chungsuppong and Iksuppong showed higher contents of total polyphenol and anthocyanin than other mulberry cultivars, while all mulberry cultivars showed high antioxidant activities. Hypoglycemic effect had a slightly higher level in Suwonppong and Cheongsuppong than in the other samples. Taken together, the new cultivar "Cheongsu" oddi can be suggested as a potential source of functional food.

• 한국식품영양학회지
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• 제22권3호
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• pp.449-455
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• 2009

The principal objective of this study was to determine the quality and potential of DHEA formation after the addition of diosgenin of yam(Dioscorea spp.) during the fermentation of soybean paste. All samples were divided into three groups based on the variety of yam. In sample A, the soy source was not separated from soybean paste and in sample B, the soybean source was separated from soybean paste. The range in salt concentration in the samples was as follows : sample A: 10.5~11.8%, samples B: 7.9~8.8%. However, no substantial differences between the two samples, in terms of salt content, were observed. The crude protein and crude lipid content were found to decrease with the fermentation time of soybean paste(passage of 30 days: 26.4~32.3% and 4.45~5.90%, passage of 60 days: 24.5~28.5% and 3.95~4.90%, respectively). As the fermentation time of soybean paste increased, the nitrogen from amino compounds increased(passage of 30 days: 531.9~687.7 mg%, passage of 60 days: 551.3~706.8 mg%). In regards to color and preference, sample B, where the soy source was separated from soybean paste, was better than sample A, where the two components were not separated. After a soybean paste fermentation time of 60 days, the diosgenin of yam, which was added to the soybean paste, was not detected in tested samples, and the contents of DHEA formation in soybean paste were as follows: sample A: $488.0\pm42.5{\sim}719.3\pm44.8{\mu}g/g$, sample B: $287.3\pm20.6{\sim}482.7{\pm}36.5{\mu}g/g$.

• 한국식품과학회지
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• 제24권6호
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• pp.592-596
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• 1992

명일엽의 일반성분중 지방과 단백질은 잎에서 가장 많았으며, 수분, 총당 및 환원당은 줄기에서 가장 많았고 회분과 섬유소는 전초에서 가장 많이 나타났다. 무기질 함량은 K와 Ca이 가장 많고, 다음으로 Na, P, Mg의 순으로 많았으며, Mn, P, Zn을 제외한 나머지 성분은 잎에서 가장 많았다. Ascorbic acid, ${\beta}-carotene$, Thiamin, Riboflavin 등의 비타민성분도 잎에서 많은 함량을 나타내었다. 총 아미노산 조성은 17종이 동정되었으며 그 함량별로는 일반적으로 glycine, glutamic acid, alanine, aspartic acid, leucine 순이었으며, 필수아미노산의 비율은 전초, 잎과 줄기에서 각각 39.74, 39.87, 37.10%이었다. 유리아미노산은 9종의 필수아미노산이 포함되어 있었고, 그 함량은 전초에서 leucine, alanine, valine, methionine, 잎에서 alanine, lysine, aspartic acid, leucine, 줄기에서 aspartic acid, methionine, glutamic acid, alanine순으로 많이 함유되어 있었다. 지방산 조성은 각 부위에서 14종이 동정되었으며 그중 linoleic acid, linolenic acid, palmitic acid, margaric acid 등이 주성분이었고, 특히 전초와 줄기에서는 linoleic acid가 각각 31.14, 43.29%이었고, 잎에서는 linolenic acid가 35.14%이었다.

• Asian-Australasian Journal of Animal Sciences
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• 제8권6호
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• pp.635-639
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• 1995

Digestibility trial was performed with carps weighing 200 g/fish. Fecal collection was made over 7 days using a settling column. The water temperature was in the range of 27 to $30{^{\circ}C}$ during whole experimental period. Fishes were fed 5 diets (Control, $F_{24}S_{13}$, $F_{16}S_{27}$, $F_8S_{40}$ and $F_0S_{56}$) containing both 32%, 24%, 16%, 8% and 0% of fish meal (F) and 0%, 13%, 27%, 40% and 56% of roasted full-fat soybean (S), respectively. Water volume in each recirculated rearing tank was maintained at 130 l with flow rate of 10-12 l/min. Apparent digestibility coefficients (ADCs) of dry matter, protein, lipid, total carbohydrates and energy in diets showed a reduction (p < 0.05) with the increase of dietary full-fat soybean level, although there was no difference in the ADCs between Control and $F_{24}S_{13}$ (p > 0.05). The ADCs of ash, Ca and P in diets significantly increased with the increase of dietary full-fat soybean level, suggesting the high availability of phosphorus in monocalcium phosphate.

• 한국작물학회지
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• 제54권3호
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• pp.314-319
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• 2009

특성이 다른 나물콩 4종을 재료로 콩나물을 재배한 후 SDE 법으로 콩나물의 향기 성분을 분석한 결과는 다음과 같았다. 1. 총 52개의 향기 성분이 분석되었으며, 품종별로 $46{\sim}50$ 개의 성분을 확인하였다. 2. 향기성분은 알콜류 16종, 알데하이드류 17종, 케톤류 10종, furan 류 2종, acid류 2종 및 기타 5종이 분석되었으며, 오리알태는 알데하이드류, 다원콩은 알콜류의 성분 수가 타 품종보다 적게 나타났다. 3. 품종별 향기성분의 상대적 함량은 오리알태가 가장 높았으나 동정된 성분의 갯수는 풍산나물콩과 녹채콩이 많았다. 4. 다원콩은 알콜류와 알데하이드류가 비슷한 함량 조성을 보였으나 기타 품종들은 알데하이드류가 알콜류보다 높은 함량을 나타내었다. 5. 4 품종 모두 2-hydroxybenzaldehyde, hexanol, 1-octen-3-ol 등이 상대적으로 함량이 높았다.

• 동의생리병리학회지
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• 제21권6호
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• pp.1499-1505
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• 2007

Peroxynitrite ($ONOO^-$) is a reactive oxidant formed from superoxide anion radical (${\cdot}\;O_2-$) and nitric oxide (NO), which can oxidize cellular components such as essential protein, non-protein thiols, DNA, low-density lipoproteins and membrane phospholipids. ${\cdot}\;O_2-$ and $ONOO^-$ have contributed to the pathogenesis of diseases such as stroke, heart disease, Alzheimer's disease and atherosclerosis. Because of damaging effects of ${\cdot}\;O_2-$ and $ONOO^-$ oxidants, Vespae Nidus, which has been known to strengthen the kidneys to preserve the vital energy. was tested as a potential specific scavenger of those oxidants. In this study, the viability of Vespae Nidus (1, 10, 50 g/ml) to scavenge ${\cdot}\;O_2-$, NO, $ONOO^-$ and so to protect cells against tert-butylhydroxyperoxide (t-BHP) induced cell death was tested. The levels of ${\cdot}\;O_2-$ and $ONOO^-$ were detected by staining with DCFH-DA and DHR 123, respectively. Protein expression levels of COX-2, iNOS and $NF{-\kappa}B$ were assayed by western blot. Vespae Nidus blocked t-BHP-induced cell death in a dose-dependent fashion. Vespae Nidus inhibited t-BHP-induced production of ${\cdot}\;O_2-$, NO and $ONOO^-$ in YPEN cells. The lipid peroxide level was increased and glutathione level was decreased in lipopolysaccharide (LPS)-treated ICR mouse, whereas the ones in the Vespae Nidus-administered group were regulated beneficially. Vespae Nidus inhibited the expression of COX-2, iNOS and NF-κB (p65 and p50) genes in LPS-treated ICR mouse. The present study suggests that Vespae Nidus is a powerful antioxidant and promotes cellular defense activity by scavenging the toxic oxidants such as ${\cdot}\;O_2-$ and $ONOO^-$.

• 한국식품영양학회지
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• 제30권1호
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• pp.148-155
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• 2017

This study aimed to investigate the effect of acorn powder and starch on the blood parameters of mice fed a high-fat diet. The moisture, crude ash, crude protein, and crude fat contents of acorns were $37.99{\pm}0.37%$, $1.61{\pm}0.06%$, $4.36{\pm}0.18%$ and $3.22{\pm}0.15%$, respectively. Acorn powder and starch contains antioxidant minerals such as selenium and zinc. The iron content was significantly higher in acorn powder than in acorn starch (p<0.05). The total cholesterol concentration was $148.50{\pm}29.72mg/dL$ in the high-fat starch diet (HFS) group, while in the high-fat diet (HF) group it was $201.50{\pm}39.15mg/dL$ (p<0.05). Serum LDL-cholesterol concentrations were significantly lower in the HFS group ($50.50{\pm}10.79mg/dL$) than in the HF group ($62.00{\pm}20.85mg/dL$; p<0.05). The serum $IL-1{\beta}$ levels in mice were not significantly different between the groups. IL-10 levels were higher in the HFP group than other groups. There is a need for strong recognition that acorns are good ingredients worldwide. It is required to develop various products using acorn powder and starch powder. There is also a need for a strategy to globalize food using acorns.

• KSBB Journal
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• 제19권1호
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• pp.57-61
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• 2004

본 연구에서는 항산화 활성을 갖는 유용한 선도 물질을 찾기 위한 일환으로 20종의 염생식물의 추출물에 대해 peroxynitrite와 DPPH 라디칼 소거 활성을 측정하였다. 그 결과 해당화 (Rosa rugosa), 개망초 (Erigeron annus), 냇씀바귀(Ixeris tamagawaensis), 띠 (Imperata cylindrica), 범행초(Tetragonia tetragonoides), 사철쑥 (Artemisia capillaris)의 MeOH 추출물에서 우수한 DPPH 라디칼 소거 효과가 확인되었다. 또한, 해당화(Rosa rugosa), 개망초 (Erigeron annus), 칠면초 (Suaeda japonica), 냇씀바귀 (Ixeris tamagawaensis), 띠 (Imperata cylindrica), 갯방풍 (Glehnia littoralis), 함초(Salicornia herbacea), 해국 (Aster spathulifolius), 범행초 (Tetragonia tetragonoides)의 MeOH 추출물과 CH$_2$Cl$_2$ 추출물에서 각각 peroxynitrite의 소거효과가 관찰되었다. 그 중에서도 해당화 MeOH 추출물의 DPPH 래디칼 소거효과는 100 $\mu\textrm{g}$/$m\ell$ (f.c.) 농도에서 87.51%로 나타났고, peroxynitrite 소거효과는 5 $\mu\textrm{g}$/$m\ell$ 농도에서 표품의 ONOO를 첨가했을 때 97.03%와 SIN-1을 첨가했을 때 98.48%로서 가장 강력한 항산화활성을 가지는 것으로 나타났다. 해당화의 peroxynitrite의 효과는 대조군으로 사용된 penicillamine보다도 우수하며, L-ascorbic acid와 비슷한 효과였다.

• Journal of Yeungnam Medical Science
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• 제27권1호
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• pp.57-62
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• 2010

Pulmonary alveolar proteinosis (PAP) is a rare disorder that's characterized by accumulation of surfactant components in the alveolar space. Idiopathic PAP is recognized as an autoimmune disease that's due to impaired alveolar macrophage function and this caused by autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF). We report here a case of pulmonary alveolar proteinosis that was deemed interstitial lung disease at the initial diagnosis. A 61-year-old man presented with intermittent blood tinged sputum and dyspnea on exertion. The man was a painter for 30 years and he had a 10 pack-years smoking history. Chest computerized tomography (CT) revealed multifocal ground-glass opacity with interstitial thickening at both lungs. His pulmonary function tests and methacholine test revealed non specific results. He was diagnosed with interstitial lung disease on the basis of the chest CT finding and occupational history. However, seven months later, his symptoms progressed. Follow-up chest CT was performed. Wedge resection via video-assisted thoracoscopic surgery (the anterior basal segment of the left lower lobe) was done. Microscopic examination showed large groups of alveoli with excessive amounts of surfactant and a complex mixture of protein and lipid (fat) molecules. Finally, he was diagnosed as having pulmonary alveolar proteinosis.