• Pediatric Infection and Vaccine
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• v.7 no.1
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• pp.113-119
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• 2000

Purpose : Rotavirus is a most common etiologic agent of pediatric gastroenteritis. The standard method to diagnose rotavirus infection was the detection of viral particles in specimens through electron microscopy. But it was complex. Enzyme immunoassay and latex agglutinin are preferred because they are relatively handy, inexpensive and take a short time, in comparison with electron microscopy. However, several reports have shown that the use of ELISA to diagnose rotavirus infection in neonates can result in false positive reactions. The main purpose of this study is to compare ELISA and RT-PCR in the diagnosis of neonatal rotavirus infection. Methods : Data presented in this study were obtained form 123 newborn babies in the nursery of the Fatima Hospital, Masan, Korea, form Jury to December, 1997. We obtained two samples of stool from each of the newborn babies and then performed the Rotazyme test and the RT-PCR. In the Rotazyme test, the results were interpreted according to visual findings. The samples were used for the RT-PCR test after at stock $-30^{\circ}C$ to identify rotavirus group A. The result of the two tests were compared. Results : The informations are divided into 73 males and females. Out of the total informations 15 were transferred from other hospitals. Their average gestational age was $38.5{\pm}1.6$ weeks. The average birth weight was $3134.8{\pm}539gm$. In the Rotazyme test, 75 samples turned out to be positive. Out of them, 55 samples(75.3%) were positive and 18 samples(24.7%) were negative in the RT-PCR. On the other hand, in the Rotazyme test, 50 samples turned out be negative. Out of them, 27 samples(54%) were positive and 23 samples(46%) were negative in the RT-PCR. Conclusion : Rotavirus infection in uncommon in neonates. The diagnosis based on visual findings using Rotazyme test has a disadvantage in the sense that it can result in false positive reactions and false negative reactions in the diagnosis of neonatal rotavirus infection.

• Journal of Life Science
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• v.22 no.5
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• pp.600-604
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• 2012

Rotavirus is the main cause of severe diarrhea in infants and young children of the world. However, the frequency of genetic alterations makes it hard to control the prophylaxis. Therefore, continuous monitoring of the rotavirus's genetic change is inevitable to prevent disease prevalence and is useful in inventing an efficient vaccine. From January 2005 to December 2010, we investigated 11,607 stool samples of acute gastroenteritis patients in the Incheon metropolitan area. About 13.18% (1,530 stool samples) of all samples had a positive reaction against rotavirus using an antigen capture enzyme-linked immunosorbent assay (ELISA). Then, the 160 stool samples were searched for subtypes of group A rotavirus by using a reverse transcription polymerase chain reaction (RT-PCR) and a nested multiplex RCR. In P sub-typing, P8 (56.3%) was an extremely prevalent genotype, followed by P6 (21.3%), and P1A (10.0%). G1 (39.4%) was most widespread in the G subtype, followed by G4 (25.0%) and G3 (18.8%). G1P8 (35.5%) was the most common G and P subtype combination, followed by G4P6 (19.3%) and G3P8 (13.1%). These results might be useful data for understanding the epidemiological status of group A-rotavirus dispersion in the Incheon metropolitan area.

• Journal of dental hygiene science
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• v.13 no.1
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• pp.91-96
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• 2013

The purpose of this study was to examine the possibility of the existence of high-risk groups of dental caries and influential factors for the high-risk groups, as there was a possibility that certain people might especially be at risk of suffering from dental caries when decayed, missing, and filled teeth index were analyzed, which were the typical indicators of dental caries. The data of the 4th National Health & Nutrition Survey for 2007, 2008 and 2009 were analyzed. Significant caries index (SiC index) were calculated, which were one of the representative devices to indicate high-risk groups of dental caries, and the SiC index and related factors were analyzed by using $x^2$ (chi-square) test. Besides, logistic regression analysis was utilized to find out influential factors, and a statistical package STATA 11.0 was employed. As a result of analyzing what factors would be linked to high-risk groups of dental caries, it's found that women were more likely to belong to high-risk groups than men (p<0.01). How the related factors affected the high-risk groups was analyzed, and it's found that those who didn't find themselves to be in good oral health were more likely to be classified into a high-risk group, and that those who brushed their teeth three times a more a day on a regular basis were more likely to belong to a high-risk group than the others who didn't (p<0.01). Thus, SiC index were calculated in this study to confirm the existence of dental caries high-risk groups, and what factors impacted on the high-risk groups was ascertained. It's required to implement efficient national policies to step up the promotion of national oral health based on the findings of the study.

• Korea journal of population studies
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• v.30 no.3
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• pp.33-56
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• 2007

This study explores the pattern of socio-demographic characteristics of divorced couples of international marriage in Korea. This paper focuses on analyzing the effect of dissimilarity between husband and wife on the duration of marriage of divorced couples. It examines whether the differences of socioeconomic characteristics of the married couples are linked to different process within their relationships and duration of marriage. Attention is focused on couple's age and education. Micro-data from divorce registration for the period of 1995-2005 are utilized. Results of analyses reveal the following. First, married couples may have different responses to dissimilarity between the partners according to the combination of nationality of the couples. This indicates that cross-border marriage does not represent the same type of union in different societies or cultures. Second, both dissimilarities of age and education show negative impacts on the marital duration of the couples with foreign wives, but there is a difference in its pattern. Age dissimilarity displays higher impacts on the duration. Third, the result also indicates that the contribution of dissimilarity of age and education on marital duration is relatively small among the couples with foreign husbands.

• Journal of Environmental Impact Assessment
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• v.29 no.2
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• pp.93-111
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• 2020

Health Impact Assessment (HIA) in Korea is conducted for specific development projects within Environmental Impact Assessment (EIA) system. However, as HIA is being carried out in the implementation stage of the development project, it sometimes has failed to take proper actions despite the significant adverse health impact. Considering an environment conflict regarding adverse health impact in developing industrial complex and the current application of HIA in EIA system, it is necessary to come up with an adequacy evaluation in the industrial complex development considering health impact. This study proposes an adequacy evaluation method considering health impact for the industrial complex development and embodies the method by applying it to actual cases. Referring to methodologies of US EPA's CalEnviroScreen 3.0 and US ATSDR's Public Health Assessment, this study proposed using indicators divided by community characteristic, background exposure and development burden as an adequacy evaluation method to consider health impact. Five indicators for community characteristic, three indicators for background exposure and seven indicators for development burden were selected through literature survey, and the weights for each indicator were calculated through Analytic Hierarchy Process's survey of experts related to HIA. Through a pilot application in the three government-led industrial complex development projects, the method was further elaborated by clarifying the evaluation data and subdividing the evaluation criteria for each indicator. Adequacy criteria of plan considering health impact could be presented in three ways to be linked to the government's policy stance on the industrial complex development criteria of total score, criteria of total score and community characteristic score, and criteria of total score and community characteristic allowed by development burden.

• Journal of environmental and Sanitary engineering
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• v.7 no.2
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• pp.95-110
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• 1992

Much progress has been made in understanding the subcellular events of the human lung injuries after acute exposure to environmental air pollutants. Host of those events represent oxidative damages mediated by reactive oxygen species such as superoxide, hydrogen peroxide, and the hydroxy, free radical. Recently, nitric oxide (NO) was found to be endogenously produced by endothelial cells and cells of the reticulo-endothelial system as endothelialderived relaxation factor (EDRF) which is a vasoactive and neurotransmitter substance. Together with superoxide, NO can form another strong oxidant, peroxonitrite. The relative importance of exogenous sources of $N0/N0_2$ and endogenous production of NO by the EDRF producing enzymes in the oxidative stresses to the heman lung has to be elucidated. The exact events leading to chronic irreversible damage are still yet to be known. From chronic exposure to oxidant gases, progressive epithelial and interstitial damages develop. Type I epithelial cells become thicker and cover a smaller average alveolar surface area while thee II cells proliferate instead. Under acute damages, the extent of loss of the alveolar epithelial cell lining, especially type II cells appears to be a good predictor of the ensuing irreversible damage to alveolar compartment. Interstitial matrix undergo remodeling during chronic exposure with increased collagen fibers and interstitial fibroblasts. However, Inany of these changes can be reversed after cessation of exposure. Among chronic lung injuries, genetic damages and repair responses received particular attention in view of the known increased lung cancer risks from exposure to several air pollutants. Heavy metals from foundry emission, automobile traffics, and total suspended particulate, especially polycystic aromatic hydrocarbons have been positively linked with the development of lung cancer. Asbestos in another air pollutant with known risk of lung cancer and mesothelioma, but asbestos fibers are nonauthentic in most bioassays. Studies using the electron spin resonance spin trapping method show that the presence of iron in asbestos accelerates the production of the hydroxy, radical in vitro. Interactions of these reactive oxygen species with particular cellular components and disruption of cell defense mechanisms still await further studies to elucidate the carcinogenic potential of asbestos fibers of different size and chemical composition. The distribution of inhaled pollutants and the magnitude of their eventual effects on the respiratory tract are determined by pollutant-independent physical factors such as anatomy of the respiratory tract and level and pattern of breathing, as well as by pollutant-specific phyco-chemical factors such as the reactivity, solubility, and diffusivity of the foreign gas in mucus, blood and tissue. Many of these individual factors determining dose can be quantified in vitro. However, mathematical models based on these factors should be validated for its integrity by using data from intact human lungs.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.3
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• pp.39-47
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• 2015

In this paper, we propose a new time synchronization algorithm using CoAP(constrained-application protocol) in sensor network environment, which handles a technique that synchronizes an explicit timestamp between sensor nodes not including an additional module for time-setting and sensor node gateway linked to internet time server. CoAP is a standard protocol for sensor data communication among sensor nodes and sensor node gateway to be built much less memory and power supply in constrained network surroundings including serious network jitter, packet losses, etc. We have supplied an exact time synchronization implementation among small and cheap IP-based sensor nodes or non-IP based sensor nodes and sensor node gateway in sensor network using CoAP message header's option extension. On behalf of conventional network time synchronization method, as our approach uses an exclusive protocol 'CoAP' in sensor network, it is not to become an additional burden for synchronization service to sensor nodes or sensor node gateway. This method has an average error about 2ms comparing to NTP service and offers a low-cost and robust network time synchronization algorithm.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2001-2006
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• 2014

The objective of this study was to investigate the diagnostic significance of EBV antibody combined detection for nasopharyngeal carcinoma (NPC) in a high incidence region of southern China. Two hundred and eleven untreated NPC patients, 203 non-NPC ENT patients, and 210 healthy controls were recruited for the study. The titers of VCA/IgA and EA/IgA were assessed by immunoenzyme assay, and the levels of Rta/IgG and EBNA1/IgA were determined by enzyme-linked immunosorbent assay. The levels of VCA/IgA, EA/IgA, Rta/IgG and EBNA1/IgA demonstrated no association with gender or age (p>0.05). The receiver operating characteristic curve and the area under the curve were used to evaluate the diagnostic value. The sensitivity of VCA/IgA (98.1%) and the specificity of EA/IgA (98.5%) were the highest. When a logistic regression model was used to combine the results from multiple antibodies to increase the accuracy, the combination of VCA/IgA+Rta/IgG, whose area under the curve was 0.99, had the highest diagnostic efficiency, and its sensitivity, specificity and Youden index were 94.8%, 98.0% and 0.93 respectively. The data suggest that the combination of VCA/IgA+Rta/IgG may be most suitable for NPC serodiagnosis.

• Journal of Broadcast Engineering
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• v.25 no.4
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• pp.545-559
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• 2020

In this paper, we propose a content creation framework that enables users without programming experience to easily create interactive media content that responds to user gestures. In the proposed framework, users define the gestures they use and the media effects that respond to them by numbers, and link them in a text-based configuration file. In the proposed framework, the interactive media content that responds to the user's gesture is linked with the dynamic projection mapping module to track the user's location and project the media effects onto the user. To reduce the processing speed and memory burden of the gesture recognition, the user's movement is expressed as a gray scale motion history image. We designed a convolutional neural network model for gesture recognition using motion history images as input data. The number of network layers and hyperparameters of the convolutional neural network model were determined through experiments that recognize five gestures, and applied to the proposed framework. In the gesture recognition experiment, we obtained a recognition accuracy of 97.96% and a processing speed of 12.04 FPS. In the experiment connected with the three media effects, we confirmed that the intended media effect was appropriately displayed in real-time according to the user's gesture.

• Transactions of the KSME C: Technology and Education
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• v.1 no.2
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• pp.199-204
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• 2013

In this paper, a new system requirement management tool and its application on the Urban Transit Maglev Project were introduced. In most R&D projects on complexity system such as transportation system, Systems Engineering(SE) activities are included on each project, and SE teams are using commercial computer-based tools to perform the SE activities. Even though SE tools help to manage huge data and documents on engineering efficiently, but well-designed functions of SE tools which support SE activities are not sufficiently used on the whole process of system engineering. In order to computer-based SE tools are to be effectively used on project management, most engineers who takes engineering and coordination roles, at least sub-project managers should be familiar to the tool and could be easily use it, but usability of commercial SE tools are very difficult for normal engineers with no experience on SE activities and SE tools. To overcome this difficulty, we developed a new system requirement management tool considering each user's scenario on using engineering tools. The developed tool could not cover whole SE processes, but designed to perform requirement engineering such as system requirements(SRs) management, specification management, traceability management, SRs' verification activity management and so on. All the entities on SR database are inter-connected by pre-recognized traceabilities, so even non-specialists on SE can easily browse the database and find entities concern, and linked information such as interacted entities, legal or engineering constraints, coordination documents, status of development and verification and so on. Also functions for SR verification tools, TPM(Technical Performance Measure) tools, DB searching tools with traceability, and report generation tools are included on the system.