• 제목/요약/키워드: Linear trend

검색결과 627건 처리시간 0.022초

파월국군장병의 고엽제 위해에 관한 예비적 역학조사 (A Preliminary Epidemiologic Study on Korean Veterans Exposed to Herbicides in Vietnam War)

  • 김정순;임현술;이홍복;이원영;박영주;김성수
    • Journal of Preventive Medicine and Public Health
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    • 제27권4호
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    • pp.711-734
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    • 1994
  • Among chemical agents in herbicides, dioxin (2, 3, 7, 8-tetrachloro dibenzo-$\rho$-dioxin : TCDD), a chemical contaminant in herbicides sprayed during the Vietnam War has been known to be the major agent causing toxic effects. Approximately 320,000 korean soldiers participated the Vietnam War from 1964 to 1974. Although the potential hazards of the herbicides among Korean veterans exposed were implicated, the problem had not been a public issue until 1991 when Korean veterans were informed U.S. companies, the herbicides manufacturer payed fund, from which a trust fund for New Zealand and Australian Class members were established in 1985. After a series of appeals and demonstration by the Korean Veterans demanding medical care and compensation for their serious health damages, a bill of medical care and compensation for herbicides victims was promulgated in March 1993 and become effective from May 1993, This study was carried out with two major objectives : the first to understand the health problems caused from the herbicides by reviewing literatures published, and the second to examine the nature and extent of health impacts among Korean veterans exposed and to develop valid study methods for the major study by interviewing and reviewing records on a part of veterans (638 persons) registered and completed medical examination in Seoul Veterans Administration Hospital from June to October 1993. The results obtained are as followings: 1. The literature review of 107 papers revealed that 1) Dioxin is teratogenic, carcinogenic and affects almost all organs including nervous, endocrine, and reproductive systems in animal experiments. 2) The diseases showing evidence of causal association were Hodgkin's disease, non-Hodgkin's disease, lung cancer, lymphoma, soft tissue sarcoma, chloroacne and polyneuropathy when judged on the basis of consistency in study results and biological plausibility. 2. Interview and medical record review study on 638 veterans, though limited validity owing to lack of control group, crude estimates of dioxin exposure levels (no biomarkers measurable), and uncertainty of diagnosis, showed that: 1) Most of the study subject's were in their 40's of age and had been dispatched to Vietnam during the period from $1965{\sim}1970$ around one year. 2) Most frequently complained symptoms in medical examination were motor weakness (32%), sensory abnormalities in extremities (23%), skin diseases (22%), and pain in extremities (20%) whereas in Interview they were more frequent in order of skin problem (44%), motor weakness (38%), sensory abnormalities and pain in extremities(17% and 19% each). Kappa indices on the same category of complaints between two sources of information were variable and relatively low. 3) On medical examination, only a part of the 638 subjects had initial impression (442 pts) and final diagnosis (218 pts) suggesting decision making on diagnosis appeared to be difficult even with all available modern medical technologies: in initial impression disorders from peripheral and central neuropathy were predominant whereas in final diagnosis various types of skin disorder were most frequent 4) When dose-response relationship between several conditions (from questionnaire) and arbitrary exposure scores were examined by CMH linear trend test, spontaneous abortion, sexual problems and health problem of offsprings showed statistically significant linear trends. However, pregnancy, accident and suicidal attempts did not show any relationship in this study capacity. 5) Among complaints, psychosis and neurosis (anxiety, phobia) in interview study, and memory disorder and psychosis in medical record study revealed linear trend. 6) Skin disorder was the only condition showing linear trend in initial impression and none in final diagnosis on medical examination. Even though objective to select out dioxin-related disease or group of diseases from this study was not achieved the research experiences provided firm basis for developing various methodological approaches. 3. From this preliminary study we concluded that a larger scale major epidemiologic study on health impacts of herbicides among Korean veterans exposed is not only Indispensible but also well designed study with more valid exposure information and diagnosis may be able to establish causal relationship between certain groups of diseases and exposure to the herbicides among Korean veterans.

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국내 화강암의 점하중강도와 일축압축강도간의 상관분석 (Correlation Between the Point-Load Strength and the Uniaxial Compressive Strength of Korean Granites)

  • 우익
    • 지질공학
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    • 제24권1호
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    • pp.101-110
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    • 2014
  • 이 연구에서는 국내에 분포하는 화강암에 대한 점하중강도($I_{s(50)}$) 와 일축압축강도(UCS) 사이의 상관관계를 선형회귀분석을 통하여 구하였다. 이를 위하여 암석시료의 물리적 물성에 근거하여 화강암 시료를 재분류하여 세 경우에 대한 회귀분석을 수행하였다. 첫째로, 풍화등급에 따른 원점회귀분석을 수행하여 풍화에 따른 상관관계를 구하였으나 풍화등급별 시료의 개수가 부족하여 만족할만한 신뢰수준의 회귀분석결과를 얻지 못하였지만, 풍화가 진행될수록 회귀직선의 기울기가 급해지는 경향을 파악할 수 있었다. 두 번째, 전체 화강암에 대한 회귀분석을 수행하기 위하여 단순선형회귀분석과 신뢰도 및 정확도를 향상시키기 위하여 부트스트랩 리샘플링법을 이용한 단순선형회귀분석을 통하여 두 강도간의 상관관계를 구하였다. 세번째로는 유사한 물리적 물성을 지닌 화강암 시료들의 평균강도에 대한 선형회귀분석을 수행하여 상관관계를 구하였다. 이 방법들을 사용하여 구한 회귀직선방정식의 기울기는 14 내외의 값을 보이고 작은 편차를 지니고 있으며 국내 화강암에 대하여 수행한 기존 연구와 유사한 값을 보이고 있었다. 그러나 16에서 43의 범위를 지닌 y-축 절편은 큰 편차를 보이기 있었기 때문에, 점하중강도로 일축압축강도를 추정할 때에는 이러한 회귀방정식의 오차범위를 고려하여야 할 것으로 판단된다.

대전지역 일부 청소년의 식생활습관과 체격과의 관계 (The Relationship Between Physique and Dining Habits of Adolescents in Daejeon)

  • 변화봉;권윤형;이태용
    • 한국학교보건학회지
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    • 제14권2호
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    • pp.279-288
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    • 2001
  • This study investigates the effect of adolescent dining habits on their physical development. We selected 200 students from the three high schools in Taejon, and surveyed with a questionnaire and collected data concerning physique from school health records. The results obtained from this study were as follows: 1. A point of intersection of two development trends of male and female students' heights was between sixth grade of elementary school and first grade of middle school. Two development trends of weights didn't have a point of intersection and male students' development trend of weights was a little higher than that of female students. 2. There were significant differences in the weight and BMI of male students. The 'regular dining' group had heavier weight and higher BMI than the other group, and the 'Eating only favorite food' group had lower weight and BMI than the other group. In female, heights of 'three meals a day' group were higher than that of 'two meals a day' group and the more snacks per day, the higher students' height was. 3. The 'regular exercise' group had significantly heavier weight and higher BMI than the other group amount females. 4. 'Regular dining' and 'Eating habits' had a positive linear relationship with male students' weight and BMI. 'Number of times of snacking' has a positive linear relationships with female students' height and a negative linear relationship with female students' BMI. Since dining habits of adolescents have not only an effect on their development but also later adults' health, to develop good habits of health and dining is a critical issue.

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QSAR방법을 이용한 CAHs와 Chlorophenol 유도체에 대한 $EC_{50}$값 예측 (Prediction of $EC_{50}$ of Photobacterium phosphoreum for CAHs and Chlorophenol Derivatives Using QSAR)

  • 이홍주;유승오;이정건;김병용;전억한
    • 한국미생물·생명공학회지
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    • 제27권1호
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    • pp.54-61
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    • 1999
  • Measurement of inhibition of bioluminescence in Photobacterium phosphoreum has been porposed as a sensitive and rapid procedure to monitor toxic substances. However, at first, $EC_{50}$ which shows degree of toxicity to each toxic substances must be calculated. QSAR (Quantitative Structure Activity Relationship) model can be used to estimate $EC_{50}$ to save time and endeavor. Moderately high correlation coefficients ($r^2{\geq}$ 0.97) were calculated from the linear correlation between $EC_{50}$ and molecular connectivity indices of CAHs (chlorinated aliphatic hydrocarbons)such as $^0X$, $^0X^V$, $^1X$, $^2X$ and $^3X^v_c$ and quadratic correlation between $EC_{50}$ and $^0X$, $^0X^V$, $^2X^V$, $^3X_c$, $^3X^V_c$ and P. It shows that the molecular connection indices in carbon structure is contributed to biological characters with linear relation and that in the other one with quadratic relation. The $EC_{50}$ of chlorophenol derivatives had quadratic relation with the value of octanol/water prtition coefficients ($r^2$=0.99) and linear and quadratic relation with the number of chlorine compound (($r^2{\geq}$0.94). This confirms the already known trend of increasing toxicity with increasing ability of a compound to diffuse through cell membrane and number of chlorine substitution.

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화염 전달 함수를 이용한 열음향 연소 불안정 해석 모델 소개 (Introduction to Thermoacoustic Models for Combustion Instability Prediction Using Flame Transfer Function)

  • 김대식
    • 한국추진공학회지
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    • 제15권6호
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    • pp.98-106
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    • 2011
  • 본 논문에서는 많은 가스터빈 산업체 및 연구기관에서 연소불안정 현상과 관련된 변수들을 예측하기 위해 가장 보편적으로 이루어지고 있는 열음향 해석 모델에 대한 기술 소개 및 최근의 연구 동향을 분석하였다. 선형 시스템 해석을 통하여 연소 불안정이 발생하는 고유 주파수 및 불안정 초기 성장률의 예측이 가능하다. 이를 위하여 정의된 시스템에서의 음향파와 열발생율 섭동간의 선형 관계식을 선형 음향 이론으로부터 유도할 수 있고, 이 관계식의 해를 구하기 위해서 가장 중요한 부분은 화염 전달 함수로부터 n-${\tau}$ 함수를 구하여 열발생율 섭동 결과에 대한 정보를 얻는 것이다. 현재까지의 연구 결과로부터 선형 특성 해석에는 상당한 진보가 이루어져 왔고, 실제 가스터빈 연소기에 적용하는 노력이 있었으나, 한계 진폭과 과도기 현상 예측을 위해서 요구되는 비선형 동적 특성 모델링 기술 개발은 현재 간단한 연소기와 버너의 적용에 머물러 있는 실정이다. 실제 복잡한 가스터빈과 같은 연소 시스템에 적용되기 위해서는 비선형 경계 조건을 고려한 시스템 동적 특성 연구와 화염의 비선형 거동을 더욱 정확히 설명할 수 있는 전달 함수에 대한 예측 기술이 선행되어야 한다.

비선형 물수지모형과 팔머가뭄심도지수를 이용한 가뭄지속기간 분석 (An Analysis of the Drought Period Using Non-Linear Water Balance Model and Palmer Drought Severity1 Index)

  • 이재수
    • 한국수자원학회논문집
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    • 제34권5호
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    • pp.533-542
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    • 2001
  • 가뭄에 대한 대책을 수립하기 위해서는 각 가뭄상태별로 가뭄의 지속기간을 산정하는 것이 선행되어야 한다. 이러한 가뭄의 지속기간 분석에 사용할 수 있는 방법에는 비선형 물수지모형과 Palmer 가뭄심도지수방법이 있다. 비선형 물수지모형은 지표면과 대기의 수분이동을 고려한 물수지방법을 추계학적 변동에 의해 야기되는 건기와 습윤기 사이의 변환기간을 모의할 수가 있다. Palmer 가뭄심도지수는 강우량과 잠재증발산량을 바탕으로 기상학적으로 필요한 강우량과 실제강우량을 비교하여 가뭄의 정도를 나타내는 물수지방법이다. 본 연구에서는 한강유역에 대해 비선형 물수지모형과 Palmer 가뭄심도지수를 이용하여 가뭄의 지속기간을 산정하였다. 비선형 물수지모형을 사용하여 산정된 토양함수비에 따른 가뭄의 지속기관과 Palmer 가뭄심도지수를 이용하여 산정된 지수별 가뭄의 지속기간이 유사하게 나타났다. 연구 결과 한강유역에서의 극심한 가뭄상태에서 습윤기로 변환되는 지속기간이 약 3년으로 산정되었다.

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차선관련 파라미터의 대칭성과 선형회귀에 기반한 차선이탈 인식 (A Lane-Departure Identification Based on Linear Regression and Symmetry of Lane-Related Parameters)

  • 이운근;이준웅
    • 제어로봇시스템학회논문지
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    • 제11권5호
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    • pp.435-444
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    • 2005
  • This paper presents a lane-departure identification (LDI) algorithm for a traveling vehicle on a structured road. The algorithm makes up for the weak points of the former method based on EDF[1] by introducing a Lane Boundary Pixel Extractor (LBPE), the well known Hough transform, and liner regression. As a filter to extract pixels expected to be on lane boundaries, the LBPE plays an important role in enhancing the robustness of LDI. Utilizing the pixels from the LBPE the Hough transform provides the lane-related parameters composed of orientation and distance, which are used in the LDI. The proposed LDI is based on the fact the lane-related parameters of left and right lane boundaries are symmetrical as for as the optical axis of a camera mounted on a vehicle is coincident with the center of lane; as the axis deviates from the center of lane, the symmetrical property is correspondingly lessened. In addition, the LDI exploits a linear regression of the lane-related parameters of a series of successive images. It plays the key role of determining the trend of a vehicle's traveling direction and minimizing the noise effect. Except for the two lane-related parameters, the proposed algorithm does not use other information such as lane width, a curvature, time to lane crossing, and of feet between the center of a lane and the optical axis of a camera. The system performed successfully under various degrees of illumination and on various road types.

다수의 수동형 캐리어를 연속 이송시킬 수 있는 새로운 영구자석 선형동기전동기의 설계 (New Design of a Permanent Magnet Linear Synchronous Motor for Seamless Movement of Multiple Passive Carriers)

  • 이기창;김민태;송의호
    • 전력전자학회논문지
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    • 제20권5호
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    • pp.456-463
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    • 2015
  • Nowadays, small quantity batch production, which is so-called a flexible manufacturing system, is a major trend in the modern factory automation industry. The demands for new transportation system are increased gradually, with which multiple passive carriers carrying materials and semi-products are precisely and individually controlled along a single closed rail. Thus, a new type of permanent magnet linear synchronous motor (PMLSM), which consists of state coils on a single rail and PM movers as many as carriers, is proposed in this paper. The rail can be segmented as modules with pairs of coils and a current amplifier, which makes the transportation system simple; therefore, the rail can be easily extended and repaired. A design method of the new PMLSM with a single carrier is proposed, which can be thought as a new version of PMLSM, a coil-segmented coreless PMLSM (CS-CLPMLSM). Experimental setup for it is made, and propulsion results show that with the help of a new effective coil selection and switching algorithms, the conventional current-based vector control is sufficient to fulfill the position and velocity control of the new PMLSM. The proposed PMLSM is expected to fulfill seamless servo-control of multiple carriers also in process line, such as a new generation of flat panel display manufacturing line.

Mapping the Spatial Distribution of IRG Growth Based on UAV

  • Na, Sang-Il;Park, Chan-Won;Kim, Young-Jin;Lee, Kyung-Do
    • 한국토양비료학회지
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    • 제49권5호
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    • pp.495-502
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    • 2016
  • Italian Ryegrass (IRG), which is known as high yielding and the highest quality winter annual forage crop, is grown in mid-south area in Korea. The objective of this study was to evaluate the use of unmanned aerial vehicle (UAV) for the monitoring IRG growth. Unmanned aerial vehicle imagery obtained from middle March to late May in Nonsan, Chungcheongnam-do. Unmanned aerial vehicle imagery corrected geometrically and atmospherically to calculate normalized difference vegetation index (NDVI). We analyzed the relationships between $NDVI_{UAV}$ of IRG and biophysical measurements such as plant height, fresh weight, and dry weight over an entire IRG growth period. The similar trend between $NDVI_{UAV}$ and growth parameters was shown. Correlation analysis between $NDVI_{UAV}$ and IRG growth parameters revealed that $NDVI_{UAV}$ was highly correlated with fresh weight (r=0.988), plant height (r=0.925), and dry weight (r=0.853). According to the relationship among growth parameters and $NDVI_{UAV}$, the temporal variation of $NDVI_{UAV}$ was significant to interpret IRG growth. Four different regression models, such as (1) Linear regression function, (2) Linear regression through the origin, (3) Power function, and (4) Logistic function were developed to evaluate the relationship between temporal $NDVI_{UAV}$ and measured IRG growth parameters. The power function provided higher accurate results to predict growth parameters than linear or logistic functions using coefficient of determination. The spatial distribution map of IRG growth was in strong agreement with the field measurements in terms of geographical variation and relative numerical values when $NDVI_{UAV}$ was applied to power function. From these results, $NDVI_{UAV}$ can be used as a new tool for monitoring IRG growth.

Trend Analysis on Korean and International Management for Activated Material Waste from Medical Linear Accelerator

  • Kwon, Na Hye;Jang, Young Jae;Kim, Dong Wook;Shin, Dong Oh;Kim, Kum Bae;Kim, Jin Sung;Choi, Sang Hyoun
    • 한국의학물리학회지:의학물리
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    • 제31권4호
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    • pp.194-204
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    • 2020
  • This study investigated and analyzed the Korean and international status of radioactive waste management for medical linear accelerators (linacs) and proceed prior research to suggest radiation safety regulations and guidelines for the safe use of radiation. We analyzed the number of linacs installed in the radiation oncology departments of 103 institutions. In addition, we analyzed the procedures and standards for disposal in Korea and foreign countries. For foreign countries, we analyzed the status based on reports from the United States, Japan, Europe, and Canada. A total of 182 linacs are installed in Korea and 95% of them use more than 10 MV of energy. In Korea, standards for managing radioactive waste from a linac, disposal procedures, and clearance criteria have yet to be established. Therefore, radioactive waste is disposed of in different ways depending on the hospitals where they originate. Japan, the US, and Canada have recommended clearance levels and procedures for linacs. Other countries have provided management guidelines for research or large-scale accelerators, but not for medical purposes. In this study, we investigated the management of radioactive waste from medical linacs in Korea and abroad. Several foreign countries have suggested a clearance level and criteria for disposing of waste storage drums. For the safe management of medical linacs, it is necessary to establish safety management regulations. In Korea, standards for disposal, such as radiation or dose limits, are required for medical linacs. A system for clearance when disposing at a medical institution should be created.