• Journal of Plant Biology
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• v.31 no.1
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• pp.33-39
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• 1988

The environmental gradient analyses were aplied for the ordination of forest vegetation in Mt. Naejang national park area in Korea. The species population sequence along soil moisture gradient, mesic to xeric, was shown in following order: Zelkova serrata, Celtis sinensis, Lindera erythrocarpa, Cornus controversa, Acer mono, Carpinus tschonoskii, Quercus aliena, Daphniphyllum macropodum, Torreya mucifera, Carpinus laxiflora, Quercus serrata, Quercus variabilis, Quercus mongolica and Pinus densiflora in tree species and Acer pseudo-siebolidianum var. koreanum, Lindera obtusiloba, Styrax obassia, Styrax japonica, Acer pseudo-sieboldianum and Rhododendron schlippenbachii in shrub species. Ten ecological groups of tree were grouped and coincided with the vegetational units in phytosociological classification by Z-M method, associations. Four vegetation types, cove forest with Zelkova serrata and Lindera erythrocarpa, hornbeam forest with Carpinum laxiflora and Carpinum tschonoskii, oak forest with Quercus variabilis and Quercus mongolica and pine forest with Pinus densiflora as the dominant species were separated in mosaic chart by the two dimensional analyses of elevation and soil moisture gradient.

• The Korean Journal of Ecology
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• v.20 no.3
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• pp.163-168
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• 1997

Taxa of the herbivorus insect larvae and their foodplant species were surveyed in a temperate forest of Namhansansung Area, Sungnam City, Kyonggi Province, in 1994-1996 growing season, Sixty two taxa of insect larvae fed on leaves of 18 woody species in 11 families during three growing season. Larvae began to be detected from the mid-April when the leafing time began. The number of larvae taxa reached to the maximum value(32 taxa) early in May, 1994. It was the time that the value of specific leaf area reached to the maximum. It decreased up to 3-4 taxa in the mid-June. Taxa of insect larvae were different year by year even in the same season. Most of larvae fed on various plant species, suggesting that they were generalist or polyphagous species. Fagaceae, Betulaceae, Ulmaceae, Rosaceae. Aceraceae, Ericaceae, Oleaceae and Styracaceae were fed on by many taxa of insect larvae, while Euonymus spp. (Celastraceae). Lindera obtusiloba(Lauraceae) and Symplocos chinensis for. pilosa(Symplocaceae) were mainly fed on by a few taxon.. Erannis, Calospilos and Phigalia were observed to feed on various species, but Illiberis, Pryeria and Chalocosia fed on only Rosaceae, Euonymus spp.(Cerastraceae) and Symplocos chinensis for. pilosa(Symplocaceae), respectively. An unidentified larva was observed only on Lindera obtusiloba (Lauraceae).

• Biomolecules & Therapeutics
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• v.18 no.2
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• pp.205-210
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• 2010

Several studies have shown that plant-derived polyphenols reduce cardiovascular accidents in high-risk patients and the inhibition of platelet function may be responsible for part of this benefit. Lindera obtusiloba is widely used in traditional herbal medicine for the treatment of cardiovascular and inflammatory diseases. Therefore, the antiplatelet and antithrombotic activities of Lindera obtusiloba Extracts (LOE) on in vitro platelet aggregation, radical scavenging activity and in vivo murine pulmonary thrombosis were examined. LOE was able to directly scavenge the stable DPPH radical in a concentration-dependent manner and its $IC_{50}$ value was 3.9 ${\pm}$ 0.1 ${\mu}g$/ml. LOE significantly inhibited collagen- and ADP-induced platelet aggregation in a concentration-dependent manner and its $IC_{50}$ value is 0.9 ${\pm}$ 0.1 mg/ml and 0.4 ${\pm}$ 0.1 mg/ml respectively. The inhibitory effect of LOE was comparable to aspirin ($IC_{50}$ values were 1.0 ${\pm}$ 0.5 and 1.0 ${\pm}$ 0.7 mg/ml, respectively). Furthermore, oral administration of LOE suppressed the death of mice with pulmonary thrombosis induced by intravenous injection of collagen plus epinephrine. Taken together, our results suggest LOE may be a promising candidate for antithrombotic agent, and the antithrombotic effect of LOE may be due to, at least in part, antiplatelet activity.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.4
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• pp.297-304
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• 2012

In this study, the antioxidative effects and inhibitory activities on tyrosinase of Lindera obtusiloba Blume (L. obtusiloba Blume) extracts were investigated. 50 % ethanol extract, ethyl acetate and aglycone fractions of L. obtusiloba Blume were used in experiments. The DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activities of ethyl acetate fraction of L. obtusiloba Blume was higher than (+)-${\alpha}$-tocopherol, known as a typical antioxidant. Reactive oxygen species (ROS) scavenging activities of extract and fractions of L. obtusiloba Blume on ROS generated in $Fe^{3+}$-EDTA/$H_2O_2$ system were similar to L-ascorbic acid, well known as a strong antioxidant. The cellular protective effects of 50 % ethanol extract and ethyl acetate of L. obtusiloba Blume on the rose-bengal sensitized photohemolysis of human erythrocytes were increased in a concentration dependent manner ($1{\sim}25{\mu}g/mL$). Ethyl acetate fraction in $10{\mu}g/mL$ concentration showed the most protective effect among extracts (${\tau}_{50}$ = 361.0 min). The inhibitory effects on tyrosinase of ethyl acetate and aglycone fractions were higher than arbutin, known as a whitening agent. These results indicate that L. obtusiloba Blume extracts can be used as antioxidant, and could be applicable to functional cosmetic ingredient.

• The Korean Journal of Mycology
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• v.39 no.1
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• pp.1-6
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• 2011

This study was conducted to reveal the diversity of arbuscular mycorrhizal fungi (AMF) in Mt. Munan, based on the morphological and molecular characters. Soil and root samples were collected from the rhizosphere of host plants including Lindera obtusiloba, Stephanandra incisa, Styrax obassis and Symplocos sawafutagi and AMF were trap-cultured with Sorghum bicolor as a host plant in a greenhouse. The spores were extracted from the cultured soils and five species were identified using morphological and molecular characteristics; Acaulospora longula, A. mellea, Ambispora leptoticha, Gigaspora margarita and Paraglomus occultum. The distribution of AMF showed different trends according to host plants. The dominant AMF species were A. longula in L. obtusiloba, A. leptoticha in S. incisa, S. obassis and S. sawafutagi.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.4
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• pp.317-323
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• 2009

Chronic exposure of solar ultraviolet (UV) light to human skin results in photoaging with wrinkle formation. This study was performed to investigate anti-wrinkle effects of Lindera obtusiloba extract (LO) on UVB-induced wrinkle formation. We first measured cell proliferation and type I pN collagen synthesis activities in normal human dermal fibroblasts. Cell proliferation and type I pN collagen synthesis were increased by 33.8 % and 91.8 %, respectively, compared with no treatment control. SKH-1 hairless mice were topically applied 5 % LO solution for 10 weeks with UVB irradiation three times a week. After 10 weeks, a visual assessment and replica assay were performed on each mouse. According to visual assessment of close-up photos and skin replica, application of 5 % LO solution inhibited UV-induced wrinkle formation in mouse skin as compared to the vehicle-applied control mice. These results indicated that LO could protect skin wrinkle formation caused by chronic photo-irradiation in hairless mice.

• The Korean Journal of Ecology
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• v.6 no.1
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• pp.1-13
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• 1983

A survey was conducted on the vegetation of southern slope of Daecheong-bong, Mt. Seolag, Located at the northern part of Taebaek mountain chain in the Central Korea. The altitudinal zonation of the vegetation was analyzed by distribution pattern of dominant species along thermal gradient, In additiion to these procedure th plant sociological studies by Braun-Blanquet(1964) were carried out. It was recognized that the vegetation is consist of 16 associations including Quercus mongolica-Lindera obtusiloba. association and the forest zone is classified into southern, central and northern part of cool temperate forest and subarctic forest.

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.467-468
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• 2010

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.405-417
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• 2012

Objectives : In the present study, anti-metastatic properties of the methanol extract of L. obtusiloba (MLO) were evaluated. Methods : To determine the effect of MLO on cancer metastasis, we checked matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) activities and expressions in B16F10 melanoma cells. In addition, we performed cell migration assay as well as invasion assay using Matrigel. Finally, we used an in vivo lung metastasis model to confirm the anti-metastatic activity of MLO. Results : 1. MLO showed potent inhibitory effects on MMP-2 and MMP-9 activities and expressions via down-regulation of activation of NF-${\kappa}B$ in B16F10 melanoma cells. 2. Melanoma cell migration and invasion were down-regulated by MLO treatment. 3. Not only in vitro model, but MLO also significantly suppressed lung metastasis in vivo. Conclusions : The present results indicate that MLO has strong inhibitory effect on cancer metastasis. Therefore, L. obtusiloba could be a valuable anti-metastatic agent.

• Korean Journal of Environment and Ecology
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• v.20 no.2
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• pp.122-129
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• 2006

To investigate the vegetation structure of mountain region from Wolgagsan to Dogabjae, 14 plots($2000m^2$) set up with random sampling method were surveyed. Two groups of Quercus variabilis-Pinus densiflora community, Quercus mongolica-Quercus acutissima community were classified by cluster analysis. Quercus variabilis, Pinus densiflora, Quercus mongolica, Quercus acutissima, Quercus dentata and Quercus serrata were found as a major woody plant species in Weolchulsan National Park region. In this area, Quercus variabilis and Pinus densiflora were dominated partially. In the future, the importance percentage of Pinus densiflora might be decreased, but those of Quercus variabilis, Quercus mongolica, Quercus acutissima and Quercus dentata might be increased. High positive correlations was proved between Quercus variabilis and Pinus rigida; Styrax japonica and Quercus dentata, Quercus acutissima; Pinus rigida and Lindera erythrocarpa, Pinus densiflora; Lindera obtusiloba and Rhododendron mucronulatum; Albizzia julibrissin and Styrax obassia, and relatively high negative correlations was proved between Diospyros kaki and Quercus dentata; Platycarya strobilacea and Lindera erythrocarpa; Symplocos chinensis for. pilosa and Quercus acutissima; Styrax japonica and Styrax obassia; Pinus rigida and Lindera obtusiloba, Fraxinus sieboldiana, Rhododendron mucronulatum; Quercus mongolica and Albizzia julibrissin. Species diversity(H') of investigated groups was ranged $1.2430{\sim}1.2892$.