• Tuberculosis and Respiratory Diseases
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• 제55권6호
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• pp.616-622
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• 2003

호흡곤란, 기침, 천명 등의 증상으로 기관지 천식을 진단 받고 이에 대한 치료를 받던 중증상 호전이 없어 시행한 흉부전산화단층촬영 및 굴곡성 기관지내시경 검사상 진단되어 기관지절개술 및 기관지성형술로 재발과 잔여 종괴 없이 치료된 기관지 평활근종 2예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 융합정보논문지
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• 제10권11호
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• pp.257-264
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• 2020

본 논문의 목적은 유방암 절제술 환자의 어깨 관절가동범위 증진을 위한 재활 연구에 관한 연구를 체계적 고찰하여 재활의 종류와 효과를 확인하는 것이다. 체계적 고찰을 위해 RISS를 포함한 3개의 데이터베이스 검색을 통해서 최종적으로 총 8편의 연구를 선정하였다. 본 연구결과 질적근거 수준은 III단계 4편(50.0%)이었고, 재활 기간은 4주에서 12주로 다양하였다. 재활의 종류는 작업치료 재활 연구가 3편(37.5%), 물리치료 재활 연구가 3편(37.5%)이었다. 어깨 관절가동범위는 굴곡, 신전, 외회전 움직임의 평가를 한 연구가 7편(87.5%)이었다. 종속변수의 측정도구로 관절가동 범위를 평가하기 위해서 각도계를 8편(100.0%)에서 사용하였다. 본 연구는 유방암 절제술로 인해 관절가동범위 제한이 있는 환자의 중재 프로토콜 개발 및 적용 시 관련 융합분야에서 기초자료를 제공할 것으로 기대한다.

• 대한두경부종양학회지
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• 제37권1호
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• pp.63-66
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• 2021

Supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP) or cricohyoidopexy (CHP) involves the removal of the whole thyroid cartilage, both true and false vocal cords, the ventricles, and the paraglottic spaces, sparing the cricoid cartilage, hyoid bone, and at least one functional and mobile cricoarytenoid unit. Reconstruction is performed by suturing of the cricoid cartilage up tightly to the hyoid bone, so trachea-releasing procedures are needed to prevent leakage at anastomosis site. In case of advanced tranglottic cancer invading tracheal tracheal wall, we need to perform additional circumferentrial circumferential tracheal wall resection. However, when we perform SCPL, circumferential resection of tracheal wall is limited because SCPL procedure itself needs releasing of tracheal length. We report a case of advanced transglottic cancer involving tracheal wall treated with induction chemotherapy and SCPL including tracheal wall resection with reconstruction of tracheal defect by sternocleidomastoid muscle flap covered with skin graft.

• Journal of Chest Surgery
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• 제55권3호
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• pp.214-224
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• 2022

Background: Studies of the prognostic role of circulating tumor cells (CTCs) in early-stage non-small cell lung cancer (NSCLC) are still limited. This study investigated the prognostic power of CTCs from the pulmonary vein (PV), peripheral blood (PB), and bone marrow (BM) for postoperative recurrence in patients who underwent curative resection for NSCLC. Methods: Forty patients who underwent curative resection for NSCLC were enrolled. Before resection, 10-mL samples were obtained of PB from the radial artery, blood from the PV of the lobe containing the tumor, and BM aspirates from the rib. A microfabricated filter was used for CTC enrichment, and immunofluorescence staining was used to identify CTCs. Results: The pathologic stage was stage I in 8 patients (20%), II in 15 (38%), III in 14 (35%), and IV in 3 (8%). The median number of PB-, PV-, and BM-CTCs was 4, 4, and 5, respectively. A time-dependent receiver operating characteristic curve analysis showed that PB-CTCs had excellent predictive value for recurrence-free survival (RFS), with the highest area under the curve at each time point (first, second, and third quartiles of RFS). In a multivariate Cox proportional hazard regression model, PB-CTCs were an independent risk factor for recurrence (hazard ratio, 10.580; 95% confidence interval, 1.637-68.388; p<0.013). Conclusion: The presence of ≥4 PB-CTCs was an independent poor prognostic factor for RFS, and PV-CTCs and PB-CTCs had a positive linear correlation in patients with recurrence.

• Journal of Gastric Cancer
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• 제23권1호
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• pp.146-158
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• 2023

Endoscopic resection (ER) is widely performed for early gastric cancer (EGC) with a negligible risk of lymph node metastasis (LNM) in Eastern Asian countries. In particular, endoscopic submucosal dissection (ESD) leads to a high en bloc resection rate, enabling accurate pathological evaluation. As undifferentiated EGC (UD-EGC) is known to result in a higher incidence of LNM and infiltrative growth than differentiated EGC (D-EGC), the indications for ER are limited compared with those for D-EGC. Previously, clinical staging as intramucosal UD-EGC ≤2 cm, without ulceration, was presented as 'weakly recommended' or 'expanded indications' for ER in the guidelines of the United States, Europe, Korea, and Japan. Based on promising long-term outcomes from a prospective multicenter study by the Japan Clinical Oncology Group (JCOG) 1009/1010, the status of this indication has expanded and is now considered 'absolute indications' in the latest Japanese guidelines published in 2021. In this study, which comprised 275 patients with UD-EGC (cT1a, ≤2 cm, without ulceration) treated with ESD, the 5-year overall survival (OS) was 99.3% (95% confidence interval, 97.1%-99.8%), which was higher than the threshold 5-year OS (89.9%). Currently, the levels of evidence grades and recommendations for ER of UD-EGC differ among Japan, Korea, and Western countries. Therefore, a further discussion is warranted to generalize the indications for ER of UD-EGC in countries besides Japan.

• 한국간담췌외과학회지
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• 제27권1호
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• pp.6-19
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• 2023

A systematic review was conducted in compliance with PRISMA statement standards to identify all studies reporting outcomes of laparoscopic resection of benign or malignant lesions located in caudate lobe of liver. Pooled outcome data were calculated using random-effects models. A total of 196 patients from 12 studies were included. Mean operative time, volume of intraoperative blood loss, and length of hospital stay were 225 minutes (95% confidence interval [CI], 181-269 minutes), 134 mL (95% CI, 85-184 mL), and 7 days (95% CI, 5-9 days), respectively. The pooled risk of need for intraoperative transfusion was 2% (95% CI, 0%-5%). It was 3% (95% CI, 1%-6%) for conversion to open surgery, 6% (95% CI, 0%-19%) for need for intra-abdominal drain, 1% (95% CI, 0%-3%) for postoperative mortality, 2% (95% CI, 0%-4%) for biliary leakage, 2% (95% CI, 0%-4%) for intra-abdominal abscess, 1% (95% CI, 0%-4%) for biliary stenosis, 1% (95% CI, 0%-3%) for postoperative bleeding, 1% (95% CI, 0%-4%) for pancreatic fistula, 2% (95% CI, 1%-5%) for pulmonary complications, 1% (95% CI, 0%-4%) for paralytic ileus, and 1% (95% CI, 0%-4%) for need for reoperation. Although the available evidence is limited, the findings of the current study might be utilized for hypothesis synthesis in future studies. They can be used to inform surgeons and patients about estimated risks of perioperative complications until a higher level of evidence is available.

• Journal of Yeungnam Medical Science
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• 제20권2호
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• pp.105-116
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• 2003

위암은 한국에서뿐만 아니라 세계적으로도 가장 중요한 암 사망 원인의 한가지로 보고되고 있다. 현재까지 외과적 수술이 위암에 대한 유일한 근치적 치료수단으로 인정되고 있으며, 가능한 한 조기에 발견하여 근치적 절제술을 시행하는 것이 가장 중요하다. 근치적 수술을 위한 술기의 표준화 및 각 수술 술기의 우열에 대한 논란이 현재까지 그치지 않고 있으나, 여기에서는 한국 및 일본에서 가장 보편적으로 인정되고 있는 위암에 대한 수술 치료의 원칙을 기술하고자 한다. 위장 절제술은 위아전절제술과 위전절제술로 대별되며 절제연은 종양의 침윤이 없는 충분한 정상조직을 확보하여야 하고 주변 림프절의 동반절제가 포함되어야 한다. 병변의 상태에 따라 주변장기의 동반절제와 광범위한 림프절 곽청술이 요구되기도 한다. 소화관의 복구는 구조적 혹은 기능적인 면에서 환자의 삶의 질과 밀접한 관련을 가지므로 상황에 따라 적절한 방법의 선택을 요한다. 술 후 환자의 삶의 질을 향상시키기 위해서 저침습성 혹은 최소한의 절제를 목적으로 하는 새로운 술기들이 소개되기도 하였다. 유문보존 위절제술, 복강경을 이용한 위설상절제 및 위아전절제술, 내시경점막절제술등을 그 예로 들수 있으며, 이러한 시술의 적응증과 안전성은 향후 임상성적의 분석을 통해 정립되어야 한다. 근치적 절제술이 불가능한 위암환자에서는 환자의 고통감소와 경구적 영양 섭취를 위해서 고식적 수술을 시행할 수 있으며, 특히, 진행성 위암에 의한 합병증으로 인해 생명이 위태로운 경우에는 응급수술이 요구되기도 한다. 진행성 위암은 수술적 치료를 하더라도 예후가 불량하므로 조기에 발견하는 것이 가장 중요하다. 최근, 한국에서는 상부 위장관에 대한 내시경 시술의 보편화로 전체 위암에서 조기위암이 차지하는 비율이 향상되고 있으며, 적절한 근치적 수술을 통해 위암의 생존율이 향상되고 있다.

• 대한후두음성언어의학회지
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• 제21권1호
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• pp.42-47
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• 2010

Backgrounds and Objects: Carcinoma of the tongue is the most common cancer of the oral cavity. A primary treatment strategy includes surgery and/or radiotherapy. Resection of the tongue often results in speech dysfunction, which depends on the site and extent of resection, type of reconstruction, and the mobility of remaining tongue. This study aimed to evaluate the characteristics of articulation errors that were resulted from the partial glossectomy without free flap reconstruction. Materials & Method : Articulation evaluations including speech intelligibility and percent of correct consonants (PCC) were performed for 24 patients who underwent partial glossectomy for their T1 or T2 tongue cancer. Mobility of the tongue, size of the resected tongue, and the history of adjuvant radiotherapy were analyzed for their relationship with the results of articulation evaluation. Results: Speech intelligibility score was $6.4{\pm}0.9$ (on 7-point scale) and overall PCC was 96.9%. There were close relationships between the size of resection and limitations in the tongue mobility, especially in "protrusion and elevation (r=-0.687)" and "retroflexion (r=-0.775)". Errors in "alveolar fricatives" and "palatal affricates" were also closely related with the size of resection (r=-0.537 and -0.538, respectively). PCC for "liquid sound" /r/ was 83.2%, which was closely related with the history of radiation therapy. Conclusion : Overall articulatory function was satisfactory in cases of early tongue cancer after partial glossectomy of a limited volume without flap reconstruction. However, the size of resection and the history of radiation therapy were closely related to the limitations in some types of tongue mobility and the resultant articulation errors.

• Journal of Chest Surgery
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• 제31권5호
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• pp.509-512
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• 1998

후측개흉술은 흉근을 절단하는 단점은 있으나 훌륭한 수술시야를 제공하므로 표준개흉술로 이용되고 있다. 이에 반하여 근육보존수직개흉술은 흉근이 보존되며 팔을 내리면 액와부 수술 상흔이 감추어지는 미용상의 장점이 있다. 그러나 수직개흉술은 흉부의 정측면에 절개선이 이루어지므로 측와위에서 수직으로 수술시야를 내려다보게 되어 흉강내의 구조물, 특히 폐문부나 첨부 및 하부의 길이가 멀어져 수술조작이 불편하다. 본 인하대병원 흉부외과에서는 수술조작에 관련된 차이를 알아보고자 후측개흉술(15례)과 수직개흉술(14례)을 이용해 폐쐐기절제술 이상의 수술을 실시한 29례에서 수술과 관련된 임상지표들을 비교관찰한 결과, 수술시간, 수술 1일과 2일의 흉관 배액량, 흉관 거치기간, 수혈 수와 수혈량, 수술 중 실혈량, 수술 후 합병증 등에서 양군간에 차이가 없었다. 이상의 결과를 볼 때 근육보존수직개흉술도 후측개흉술과 마찬가지로 폐절제술시 안전하게 사용될 수 있다고 본다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권1호
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• pp.44-48
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• 2011

Maxillary defects are inherently complex because they generally involve more than one midfacial component. In addition, most maxillary defects are composite in nature, and often require bony support, as well as a mucosal lining for reconstruction. Therefore, midfacial bone and soft tissue defects present a unique challenge because they require a complex arrangement of tissues in a relatively limited space. This might be difficult to achieve only with free osteocutaneous flaps. The use of bone grafts allows greater flexibility in a reconstruction but is limited by graft resorption. We report a case of a patient reconstructed with a lateral arm free flap, iliac bone graft, sagital split ramus osteotomy for the reconstruction of a right maxillary defect zygomatico-maxillary defect caused by a zygomatico-maxillary malignant tumor resection.