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Topiramate can reduce the number of episodic attacks in cyclic vomiting syndrome : a case report (Topiramate 투여로 호전된 주기성 구토증 1례)

  • Yum, Mi-Sun;Bae, Keun Wook;You, Su Jeong;Ko, Tae Sung
    • Clinical and Experimental Pediatrics
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    • v.50 no.4
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    • pp.386-389
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    • 2007
  • Cyclic vomiting syndrome (CVS) is a paroxysmal, recurrent vomiting disorder of unknown pathophysiology and target organ. It has been hypothesized that CVS shares the same mechanism as migraine. We describe here a 5-year-old boy with CVS characterized by episodic vomiting attacks. These recurrent vomiting episodes began at 3 years of age, occurred every month and lasted for 5 days at a time. At the time of admission, no abnormal physical or neurological findings were observed and laboratory findings, including brain MRI and endoscopic examination, revealed nothing specific. The vomiting episodes were self-limited but recurrent and severely interrupted his daily life. When this patient was treated with topiramate, he showed a marked increase of symptom-free periods.

A Systematic Review of Clinical Studies for Herbal Medicine of Dementia - based on Korean Literature - (치매의 한약물 치료에 대한 체계적 임상논문 고찰 - 국내문헌을 중심으로 -)

  • Kwon, Yong-Ju;Cho, Hye-Young;Whang, Wei-Wan;Cho, Seung-Run
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.4
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    • pp.151-161
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    • 2010
  • Objectives : This study aimed to evaluate any clinical studies regarding the herbal medicine for dementia focusing on Korean literature for future rigorous clinical research. Methods: Every article relevant to dementia was initially obtained from oriental medical related journals by electronic search at journal web sites or manual searches. Journals were limited to those registered with the Korea Research Foundation. From initial findings. two independent reviewers selected clinical articles and these articles were further analyzed separately by predefined criteria according to prospective and retrospective studies. For randomized controlled trial and non randomized controlled trial. quality assessment was also conducted. Results: From ninety seven patients initially obtained articles. twenty three patients were finally analyzed. One article was randomized controlled study. Four articles were prospective whereas eighteen patients were retrospective. In the qualitative evaluation of prospective articles. there was deduction regarding pre-calculated study size and prospective data collecting. Assessment measurement most frequently used was Mini Mental State Examination. The order of frequency of use herbs were identified. Conclusions : According to our study. the herbal medicine for dementia in general showed a positive effect in the cognitive aspects of dementia patients. Further well-designed randomized controlled studies should be conducted.

The Impact of Socioeconomic Factors on the Gender Differences of Disability and Subjective Health Among Elderly Koreans (노인의 장애 및 주관적 건강의 남녀차이와 사회경제적 요인의 영향)

  • Jeon, Gyeong-Suk;Jang, Soong-Nang;Rhee, Seon-Ja
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.3
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    • pp.199-207
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    • 2009
  • Objectives : Research on the gender differences of health among older Korean people has been limited compared with the research for other stages of life. This study first examined the patterns and magnitude of the gender differences of health in later life. Second, we examined the gender differences in the health of older men and women that were attributable to differing socioeconomic conditions. Methods : Using the nationally representative 2005 Korean National Health and Nutrition Examination Survey, the gender differences in disability and subjective poor health were assessed by calculating the age adjusted and gender-specific prevalence. Logistic regression analyses were used to assess if the differences between the men and women for health could be explained by differential exposure to socioeconomic factors and/or the differential vulnerability of men and women to these socioeconomic factors. Results : Our results indicated that older women were more likely than the men to report disability and poor subjective health. The health disadvantage of older women was diminished by differential experiences with socioeconomic factors, and especially education. The differences shrink as much as 43.7% in the case of disability and 35.4% in the case of poor subjective health by the differential exposure to educational attainment. Any differential vulnerability to socioeconomic factors was not found between the men and women, which means that socioeconomic factors may have similar effect on health in both genders. Conclusions : Differential socioeconomic experience and exposure between the men and women might cause gender difference in health in old age Koreans.

Escherichia coli septicemia concurrent with mycotic infection in captive salt water crocodiles in Bangladesh

  • Sultana, Sajeda;Chowdhury, Emdadul H.;Parvin, R.;Saha, Shib S.;Rahman, Sheik M.;Haider, M.G.;Arif, Abu S.M.;Rahman, Md. Siddiqur;Song, Hee-Jong
    • Korean Journal of Veterinary Service
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    • v.35 no.1
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    • pp.47-52
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    • 2012
  • Crocodile farms are getting popular in Bangladesh in an economic point of view. In one of the farms, some crocodiles were found sick and three of them died between May and July in 2006. This investigation was performed to diagnose the cause of the death. Routine postmortem examination was conducted. Samples were collected in 10% neutral buffered formalin for histopathology and in falcon tube for microbiological study. Additional swabs were collected in nutrient broth. Histopathological and microbiological studies were conducted using routine procedures. In addition Giemsa, Gram and PAS stains were performed to detect the organism in tissues. Grossly, esophagus, trachea, lungs, liver, spleen, heart and kidney were congested. Intestine, rectum and colon were hemorrhagic. Clay colored material was found in colo-rectum. Purulent exudates in lungs and thick and cloudy pericardial fluid in pericardial sac were found. Histologically, multifocal granulomatous inflammation was evident in lung, liver, kidney, intestine and colon with bacterial colonies, fungal spores and hyphae. These bacteria were appeared as Gram negative. Fungal hyphae and spores were detected in liver, lungs and colon by using PAS stain. Bacteriologically, E. coli were isolated from lungs exudates, pericardial fluids and intestinal fluids. Therefore, it can be concluded that 3 crocodiles died due to E. coli septicemia concurrent with mycotic infection.

Natural Environment Conservation Planning for Sustainable Development (지속가능한 자연환경보전계획 수립방향 연구)

  • Byun, Byungseol
    • Journal of Wetlands Research
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    • v.6 no.4
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    • pp.71-81
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    • 2004
  • Recently the ecosystem has been seriously damaged by reckless development. The Ministry of Environment is now shifting its policy from one of "end-of-pipe" management and being regulation-centered to one striving to be preparatory and self-regulating. The nature conservation plan has been focused on protecting only the wildlife, so a systematic conservation of the nationwide ecosystem is inherently limited. To go beyond this limit, the strengthening of the link between the natural environmental conservation plan and the land use development plan is necessary. This study first diagnosed the "AS-IS" status of the natural environment conservation planning process and then envisioned a "TO-BE" image of the organic link between that plan and the land/metropolitan development plan. In conclusion, it was determined that the system of planning should be reformed and the focus of the planning should be shifted from source oriented planning to spatial environment planning. A biotope map should be drawn during this process and the examination criteria, methodology, and drawing standards are needed. The central government and self-governing bodies should have reasonable roles and responsibilities, and cooperate for more efficient conservation planning.

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The Effect of Lateral Approximations on the Survival of the Free Composite Flap (이식편의 측면접합이 복합조직이식의 생존에 미치는 영향)

  • Kim, Deok-Woo;Park, Seung-Ha;Lee, Byung-Ihl
    • Archives of Reconstructive Microsurgery
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    • v.16 no.2
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    • pp.57-62
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    • 2007
  • Non-vascularized free composite graft is one of the simple and effective reconstructive options, but its clinical use has been limited due to questionable survival rate. Early vascularization is essential for graft survival and is mainly carried out via recipient bed or repaired sites. This study was designed to investigate the effect of the lateral marginal approximations on the survival of the free composite flap using a model of skin-subcutaneous composite graft in rats. Thirty 1.5 ${\times}$ 1.5 $cm^2$ sized square shape composite flaps were elevated freely and reposed in place immediately on the dorsum of five Sprague-Dawley rats, and divided into five groups of six flaps. In all groups, graft bed was isolated with silastic sheet. In the group I, all sides of flap were repaired with blockage of silastic sheet insertion. Three, two, and one sides of flap were treated with same method in the group II, III, and IV respectively. Other sides of flaps were repaired without blockage, so all sides of flap were repaired in the group V. At 14 days later, the survived rate of each flap was evaluated according to the numbers of the repair sites. Histological examination was done for the evaluation of new vessel development quantitatively. Overall survived rates were increased with the number of repaired sites, but the group V only showed increased survival rate up to more than fifty percentile of the flap size with a significant difference statistically. New vessels were also increased in proportion with the number of repaired sites, and the repair site more than two had significant effect on the increased number of new vessels. In conclusion, at least more than three-fourth of flap circumference should be repaired in order to increase flap survival effectively under the condition of bed isolation.

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Comparison of Food and Nutrient Consumption Status between Displaced North Korean Children in South Korea and South Korean Children (한국 거주 북한이탈 어린이와 남한 어린이의 식품 및 영양소 섭취 현황 비교)

  • Lee, Soo-Kyung;Nam, So-Young
    • Korean Journal of Community Nutrition
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    • v.17 no.4
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    • pp.407-418
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    • 2012
  • Many displaced North Koreans (NK) are living in South Korea (SK); however nutrition research with the displaced NK is limited. This study examined food and nutrient consumption status of displaced NK children (6-18 year-old) currently living in SK. A total of 154 children were recruited, and a pre-tested dietary behavior questionnaire, food frequency questionnaire, 24-hr recall method were used. Sex- and age-matched SK children (n = 462) randomly selected from 2009-2010 Korea National Health and Nutrition Examination Survey were used as the comparison group. This study found that more NK children skipped breakfast (37%) and dinner (11%), and ate breakfast (38.8%) and dinner (18.2%) without family members than SK children. Many NK children reported that they rarely ate bread, rice cake, hamburger, pizza, fried food, candy. NK children consumed significantly less energy and nutrients (except calcium) and obtained more energy from fat and protein than SK children. Overall index of nutrient quality in NK children, however, was generally good. Length of stay in SK and breakfast skipping rates were significantly associated with lower diet quality. Therefore, nutrition education with displaced NK children should target those who recently came to SK. How to incorporate "new" foods, generally high in energy, sugar, or fat, in healthy ways and importance of breakfast should be emphasized. The growth patterns of the displaced NK children who were born and raised in food-deprived environments and will grow in food-affluent environments of SK should be monitored for health promotion of the NK children and for nutrition policy of the future united Korea.

Cytologic Findings of a Plasmacytoid Variant of Urothelial Carcinoma of the Urinary Bladder in Voided Urine (방광의 형질세포모양 요로상피암종의 요 세포소견)

  • Song, Joo-Yeon;Yoon, Hye-Kyoung;Choi, Sung-Hyup;Jung, Soo-Jin
    • The Korean Journal of Cytopathology
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    • v.17 no.1
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    • pp.51-55
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    • 2006
  • The plasmacytoid variant is an extremely rare form of urothelial carcinoma in which the malignant cells resemble those of plasmacytoma. We report the cytologic features of 3 cases of this disorder. All 3 patients were male and presented with painless macroscopic hematuria. The voided urine cytology revealed a few scattered clusters of tumor cells in a bloody background. Each tumor cell had an abundant amount of cytoplasm that was clear or densely stained and characterized by eccentrically located nuclei. A histological examination of tissue obtained from a radical cystectomy confirmed the cytologic diagnosis in each 3 case, revealing a diffusely infiltrating tumor composed of round, noncohesive tumor cells demonstrating a high nuclear grade. These cells had infiltrated the tunica propria in 2 cases, but were limited to the submucosa in 1 case. The tumor cells were plasmacytoid in appearance, each demonstrating an eccentric nucleus and dense cytoplasm, as seen in the cytologic findings. All of the tumors were immunoreactive for pancytokeratin, CK7, CK20; negative for epithelial membrane antigen (EMA), leukocyte common antigen (LCA), kappa, lambda, and CD79a. Thus, it is important to consider the plasmacytoid variant of urothelial carcinoma in addition to plasmacytoma or lymphoma as a diagnosis when encountering plasmacytoid tumor cells in a voided urine sample.

Estimation of primary production of the waters around rack oyster farm at Wando, Korea

  • Jeong, Woo-Geon;Cho, Sang-Man
    • Fisheries and Aquatic Sciences
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    • v.21 no.4
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    • pp.9.1-9.7
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    • 2018
  • To establish a comprehensive management strategy, as part of the optimization of cultural practice for an oyster rack culture system, we used a numerical model to estimate the primary production in the waters on the eastern coast of Wando island, South Korea. The estimated primary production ranged from 17.12 to $1052.55mgC\;m^{-2}day^{-1}$ ($204.22{\pm}224.75mgC\;m^{-2}day^{-1}$ in average). Except for the times of peak phytoplankton blooms, the estimated primary production (PP) was consistently under $200mgC\;m^{-2}day^{-1}$, which is more similar to the value of PP measured off the western coast of South Korea than the southern coast. No clear relationship was observed between nitrogen content and rainfall with the exception of heavy rainfall events, indicating that precipitation might not be the main source of nutrients in these waters. No clear influence was observed from Doam tidal discharge, located 24 km north from these waters due to main tide comes in this area from the channel between Gunwe-myeon in Wando island and Pukpyeong-myeon in Haenam-gun. Because of the shallow water depth and strong tidal current, resuspension of sediments, which causes an input of nitrogen into the system, could be easily caused by even mild wind and the infrequent passing of ships. Microscopic examination of the phytoplankton composition showed additional contribution of benthic species such as Paralia sulcata into the waters, which increase the productivity of oyster farms in the waters. The availability of nitrate and phosphate for primary production was temporarily limited throughout most of the spring and autumn blooming season.

A Study on Instrumentation Results Analysis Using Artificial Neural Network in Tunnel Area (인공신경망을 이용한 터널시공 시 계측결과 분석에 관한 연구)

  • Lee, Jong-Hwi;Han, Dong-Geun;Byun, Yo-Seph;Chun, Byung-Sik
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.09b
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    • pp.21-31
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    • 2010
  • Although it is important to reflect the accurate information of the ground condition in the tunnel design, the analysis and design are conducted by limited information because it is very difficult to get it practically on considering various geography and geotechnical condition. So construction management of information concept is required to manage immediately on the field condition because it is very time-consuming to establish the countermeasure of underground reinforcement and the pattern change of Bo. Therefore, when construction is on tunnel area, examination of accurate safety and prediction of behavior is performed to overcomes the limit of predicting behavior by using Artificial Neural Network(ANN) in this study. Firstly, the field data was secured. Secondly, suitable structure was made on multi-layer perceptrons among the ANN. Thirdly, learning algorithm-propagated applies to ANN. The data for the learn of field application using ANN was used by considering impact factors, which influenced the behavior of tunnel, and performing credibility analysis. crown displacement, spring displacement, subsurfacement, and rock bolt axial force are predicted at the tunnel construction and on-site application was confirmed by using ANN from analyzing and comparing with measurement value of on-site. In this study, the data from Seoul Highway $\bigcirc\bigcirc$ tunnel section was applied to the ANN Theory, and the analysis on the investigate value and the reasoning for the value associated with field application was performed.

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