• 대한지역사회영양학회지
• /
• 제19권1호
• /
• pp.84-94
• /
• 2014

Periodontal disease is one of the most common chronic inflammatory diseases in the oral cavity, and this is the leading cause of loss of teeth. Studies on the association between diet and periodontal diseases are very limited. The purpose of this study was to investigate the association between food and nutrient intakes and the prevalence of periodontitis. Subjects were 13,391 adults participating in the 2008-2010 Korea Health and Nutrition Examination Survey. Periodontitis was diagnosed by dentists using the Community Periodontal Index. Nutrient intakes were estimated by the 24-hour dietary recall. Consumption frequencies of foods were from the food frequency questionnaire. Subjects were categorized into 'smoking' or 'non-smoking' groups. Multiple logistic regression analysis was applied to determine the association between diet and periodontitis. The proportions of subjects having periodontitis were 26% in the non-smoking group and 37.5% in the smoking group. In the nonsmoking group, intakes of fruits, dairy products, green tea, energy and vitamin C were inversely associated with the prevalence of periodontitis, but fish and coffee intakes were positively associated with the prevalence of periodontitis after adjusting for covariates. In the smoking group, protein and retinol intakes were inversely associated with the prevalence of periodontitis after adjusting for covariates. These results suggest that certain food and nutrient intakes such as fruits, dairy products, green tea, vitamin C, protein, or retinol intakes may affect the prevalence of periodontitis among Korean adults. Further studies are required to confirm these findings in other research settings.

• 보존과학회지
• /
• 제17권
• /
• pp.57-64
• /
• 2005

청평사 강선루 회전문 부근에서 출토된 조선시대 $16\~17$세기 철물과 철촉에 대한 금속조직학적으로 조사하기 위하여 유물에서 부식되지 않은 시편을 채취하여 마운트와 연마 및 부식을 시켜 금속조직을 관찰하고 비금속개재물부분은 SEM으로 관찰한 뒤 EDS로 분석하였다. 금속학적 조직조사와 SEM-EDS분석을 통하여 철물과 철촉은 고체저온환원법에 의한 순철에 가까운 괴련철 혹은 해면철을 이용하여 철을 생산하고, 단야로 같은 곳에서 침탄을 하여 탄소량을 높인 것으로 밝혀졌다. 또한 철물은 탄소량을 어느 정도 높인 다음 담금질과 열처리과정을 반복하여 철기의 강도를 인위적으로 많이 높이는 작업을 한 것으로 밝혀졌다. 이번 조사연구를 통하여 조선시대에도 괴련철을 소재로 하여 철을 생산하였다는 것을 알 수 있어 의미 있는 결과를 얻었다.

• 한국산학기술학회논문지
• /
• 제21권2호
• /
• pp.280-286
• /
• 2020

일반적으로 사용되고 있는 합성수지인 PVC, PET 소재로 이루어진 카드는 쉽게 산화되거나 분해되지 않아서 사용 후에 폐기물로써 소각 또는 매립 처리되어지고 있으며, 소각 과정에서 환경호르몬과 연소가스등의 공해 문제를 일으킨다. 또한 매립 시에는 분해되지 않고 반영구적으로 쓰레기로 남아있어 환경오염을 일으키는 문제점 있다. 본 연구에서는 현재 사용하고 있는 카드의 문제점을 해결할 수 있는 대체 재료로써 대표적인 생분해성 소재인 폴리락트산(PLA : Polylacticacid)을 사용하여 이러한 문제점을 해결하고자 하였다. 그러나 PLA 소재로만 얇은 시트형태의 카드 기재가 만들어질 경우 재료 본래의 물성이 제한되어 저온 충격강도, 고온 안정성, 휨(Bending) 특성 등이 불충분하여 카드로써의 사용범위도 제한될 수밖에 없는 문제점을 가지고 있다. 이를 해결하기 위하여 PLA와 물성보강을 위한 원료의 적절한 배합 조성비를 검토하고, 결정화 핵제 및 첨가제 등의 조성물 검토와 나노컴파운드 기술을 통한 최적의 생분해성 컴파운드 조성물을 제조, 평가 하였다. 또한, 어닐링 (Annealing) 기술을 적용한 라미네이팅 공정을 통해 생분해성 범용 카드로써의 고기능화를 검증하였다.

• 미술이론과 현장
• /
• 제2호
• /
• pp.121-146
• /
• 2004

Compared to the influences of Korean art journalism, the researches on them are rarely conducted. This study aims to examine the influence of art journalism in art magazines in Korea. Although it is essential to consider media, journalism, public opinion altogether, I focused only on the media due to the absence of previous studies I have analyzed the current conditions of korean art journalism, types of feature articles, sponsors, their relations with articles and the comparison with foreign art journalism in terms of production conditions. There have been about one hundred art magazines published in previous sixty years and currently there are twenty three. Monthly periodicals are the majority: the publishers are sorted out as publishing houses, galleries, newspaper company in order specialized art magazines developed from the eighties. Through an examination of feature articles in these art magazines, I found that they repeated similar art issues and covered the same artists sponsors and articles. Moreover, when the magazines went through the conflicts between managers and editors, the ascendency of managers obstructed the development of art journalism regarding journal quality. These days, art journalism have been comparatively regressed compared to other art systems such as art museums, curatorship, international aft festivals, distributions and art promotion policies. The main causes for failure were the lack of professional management, the limited effort to diversify sponsors, and the repetition of the same informants and events without making an effort to be specialized Magazines are published media which contribute to the creation of culture, distribution, and preservation. Therefore art magazines can be said the most influential media in forming art culture and distributing it. It is quite necessary to reform the problems of repeating of information and the lack of speciality in conjunction with the commitment of management and editorialship.

• Journal of Korean Neurosurgical Society
• /
• 제37권6호
• /
• pp.410-415
• /
• 2005

Objective: The aim of our study is to evaluate the effectiveness of unilateral hemilaminectomy for bilateral decompression in elderly patients with degenerative spinal stenosis. For this purpose, we studied the co-morbid condition and clinical outcome of patients who underwent decompressive surgery using the unilateral approach technique. Methods: Thirty-four patients over 65years of age who underwent unilateral partial laminectomy for bilateral decompression from January 2000 to October 2003 were analyzed. These patients were studied for preoperative co-morbid condition and physical status according to the American Society of Anesthesiologists(ASA) classification, postoperative morphometrical change, and clinical outcomes, including visual analogue scale(VAS) score. The mean follow-up was 23months (range 6 - 48months). Results: A patient's physical status was recorded as class I, II, or III by ASA classification, which correlated to 41.2%, 44.1%, and 14.7% of patients, respectively. The cross-sectional area of the pre- and postoperative dural sac at the level of the stenosis was $52.5{\pm}19.9mm^2$ and $110.6{\pm}18.2mm^2$, respectively. The outcome was excellent in 8.8%, good in 58.8%, fair in 23.6%, and poor in 8.8% of the patients. The VAS was changed postoperatively to $3.1{\pm}1.2$. There was no operation-related transfusion yet there was no evidence of postoperative instability at the follow-up examination. Conclusion: Unilateral laminectomy for bilateral decompression, in spite of the limited exposure, can result in satisfactory decompression of the lumbar spinal stenosis and tolerable clinical outcome. This approach is thought to be appropriate for elderly patients who have a greater surgical burden.

• 한국한의학연구원논문집
• /
• 제18권3호
• /
• pp.95-101
• /
• 2012

Objectives : This work aimed to reveal the relations between Health-related Quality of Life and Body mass index, age, gender in Sasang Constitution. Methods : 1108 subjects who visited Korean medicine hospital in Jeonju for regular health examination surveyed SF-12. Their Sasang constitution were diagnosed by 1 Sasang constitution medicine specialist. ANOVA (Analysis of variance) was carried out to compare SF-12 sub scales differences among each constitutions. Regression analysis was performed to reveal effects in changes of BMI, age, and gender to SF-12 sub scales. Results : TE type gets more BMI, has more physical limits, even those of SE and SY type are not limited by these reasons. Contrary, SE type feels more vitality when they get higher BMI. SE type women have low mental health status than that of SE type men, though they don't have any specific disease. Conclusions : This is the first work of analysis between quality of life and Sasang Constitution's BMI, age, and gender. To reveal factors which affect quality of life in each Sasang constitutions, more rigorous works are required.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권2호
• /
• pp.699-705
• /
• 2015

Vemurafenib has recently been used as drug for treatment of melanomas with $BRAF^{V600E}$ mutation. Unfortunately, treatment with only vemurafenib has not been sufficiently effective, with recurrence after a short period. In this study, three vemurafenib-resistant $BRAF^{V600E}$ melanoma cell lines, $A375P^R$, $A375M^R$ and SKMEL-$28^R$, were established from the original A375P, A375M and SKMEL-28 cell lines. Examination of the molecular mechanisms showed that the phosphorylation levels of MEK and ERK, which play key roles in the RAS/RAF/MEK/ERK signaling pathway, were reduced in these three cell lines, with increased phosphorylation levels of pAKTs limited to SKMEL-$28^R$ cells. Treatment of SKMEL-$28^R$ cells with 100 nM paclitaxel resulted in increased apoptosis and decreased cellular proliferation, invasion and colony formation via reduction of expression levels of EGFR and pAKTs. Moreover, vemurafenib-induced pAKTs in SKMEL-$28^R$ were decreased by treatment with an AKT inhibitor, MK-2206. Taken together, our results revealed that resistance mechanisms of $BRAF^{V600E}$-mutation melanoma cells to vemurafenib depended on the cell type. Our results suggested that paclitaxel should be considered as a drug in combination with vemurafenib to treat melanoma cells.

• 한국컴퓨터정보학회논문지
• /
• 제25권7호
• /
• pp.113-123
• /
• 2020

수면 장애 중 폐쇄성수면무호흡증은 비교적 흔한 질병 중 하나이다. 환자들은 수면다원검사를 통해 해당 질환의 여부를 알아볼 수 있다. 그러나 수면다원검사를 이용한 폐쇄성수면무호흡증 진단에 관한 한, 늘어나는 환자 수, 비싼 검사 비용, 검사 중 불편함, 수용 인원 제한 등 현실적인 문제점들이 지적됐다. 이에 따라, 수면다원검사를 대체할 목적으로 연구자들은 생체 신호를 활용한 기계학습 기반 폐쇄성수면무호흡증 진단 연구들을 활발히 진행해 왔다. 이 시점에서, 우리는 생체 신호 데이터를 기반으로 기계학습 기법을 적용하는 폐쇄성수면무호흡증 진단 연구를 복기한다. 그 결과, 본 논문은 복기 된 연구들에 대한 최신 분류 체계를 제시하고 그 연구들의 종합적인 비교 분석 결과를 제공한다. 또한, 본 논문은 생체 신호를 활용한 연구들의 다양한 한계점을 밝히고 사용된 기계학습 기법의 활용성에 대한 여러 개선점을 제안한다. 끝으로, 본 논문은 생체 신호를 활용한 기계학습 기법 적용과 관련한 향후 연구 주제를 제시한다.

• 대한지리학회지
• /
• 제39권4호
• /
• pp.683-695
• /
• 2004

우리나라에서 지리학전공자들의 사회진출 영역이 한정되어 고용시장의 적체현상이 발생하는 까닭에 지리학의 활동영역을 확대시키는 노력의 일환으로 프랑스 지리학계의 사례를 통하여 지리학자의 공공직 진출의 가능성을 논의코자 본 연구를 실시하였다. 지리학은 고대부터 사상들의 분포관계와 지역특성에 대한 지식을 제공함으로써 효율적인 통치를 보좌하는 역할을 담당하였으며 영토의 확장과 관리를 위한 지역연구의 활용이 활발하여 유럽 국가들에서는 지리학자들의 정치참여를 독려하는 분위기였다. 한국에서도 최근 여러 차원의 사회진출이 확대되고 있는 실정이다. 프랑스 지리학계는 지리적 시각과 접근방법의 특성이 지리학자들의 공공직 진출을 용이하게 만드는 것으로 평가하고 있다. 특히 지역개발 환경, 부문적 경제, 관광개발, 국제정치 분야 등이 지리학자들이 진출하기에 적절한 공공직 분야이다는 의견이다. 따라서 한국지리학계가 사회과학 전반적인 지식에 대해 개방적인 태도를 견지하며 지리학 특정분야의 전문지식 획득과 동시에 지리학 전반의 고른 지식을 배양하는 것이 공공직 참여를 확대할 수 있는 길이 될 것이다.

• Journal of Preventive Medicine and Public Health
• /
• 제48권5호
• /
• pp.257-263
• /
• 2015

Objectives: Although the prevalence of depressive disorders in South Korea's general population is known, no reports on the prevalence of depression among patients who visit primary care facilities have been published. This preliminary study was conducted to identify the prevalence of depressive disorder in patients that visit two primary care facilities. Methods: Among 231 consecutive eligible patients who visited two primary care settings, 184 patients consented to a diagnostic interview for depression by psychiatrists following the Diagnostic and Statistical Manual of Mental Disorders-IV criteria. There were no significant differences in sociodemographic characteristics such as gender, age, or level of education between the groups that consented and declined the diagnostic examination. The prevalence of depressive disorder and the proportion of newly diagnosed patients among depressive disorder patients were calculated. Results: The prevalence of depressive disorder of patients in the two primary care facilities was 14.1% (95% confidence interval [CI], 9.1 to 19.2), with major depressive disorder 5.4% (95% CI, 2.1 to 8.7), dysthymia 1.1% (95% CI, 0.0 to 2.6), and depressive disorder, not otherwise specified 7.6% (95% CI, 3.7 to 11.5). Among the 26 patients with depressive disorder, 19 patients were newly diagnosed. Conclusions: As compared to the general population, a higher prevalence of depressive disorders was observed among patients at two primary care facilities. Further study is needed with larger samples to inform the development of a primary care setting-based depression screening, management, and referral system to increase the efficiency of limited health care resources.