• Sleep Medicine and Psychophysiology
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• v.5 no.2
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• pp.119-133
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• 1998

Attentional processes facilitate cognitive and behavioral performance in several ways. Attention serves to reduce the amount of information to receive. Attention enables humans to direct themselves to appropriate aspects of external environmental events and internal operations. Attention facilitates the selection of salient information and the allocation of cognitive processing appropriate to that information. Attention is not a unitary process that can be localized to a single neuroanatomical region. Before the cortical registration of sensory information, activation of important subcortical structures occurs, which is called as an orienting response. Once sensory information reaches the sensory cortex, a large number of perceptual processes occur, which provide various levels of perceptual resolution of the critical features of the stimuli. After this preattentional processing, information is integrated within higher cortical(heteromodal) systems in inferior parietal and temporal lobes. At this stage, the processing characteristics can be modified, and the biases of the system have a direct impact on attentional selection. Information flow has been traced through sensory analysis to a processing stage that enables the new information to be focused and modified in relation to preexisting biases. The limbic and paralimbic system play significant roles in modulating attentional response. It is labeled with affective salience and is integrated according to ongoing pressures from the motivational drive system of the hypothalamus. The salience of information greatly influences the allocation of attention. The frontal lobe operate response selection system with a reciprocal interaction with both the attention system of the parietal lobe and the limbic system. In this attentional process, the search with the spatial field is organized and a sequence of attentional responses is generated. Affective, motivational and appectitive impulses from limbic system and hypothalamus trigger response intention, preparation, planning, initiation and control of frontal lobe on this process. The reticular system, which produces ascending activation, catalyzes the overall system and increases attentional capacity. Also additional energetic pressures are created by the hypothalamus. As psychophysiological measurement, skin conductance, pupil diameter, muscle tension, heart rate, alpha wave of EEG can be used. Event related potentials also provide physiological evidence of attention during information process. NI component appears to be an electrophysiological index of selective attention. P3 response is developed during the attention related to stimulus discrimination, evaluation and response.

• Toxicological Research
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• v.17 no.2
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• pp.73-82
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• 2001

The incidence and distribution of necrotic and apoptotic neural cells, and activated astrocytes in the brain of rats intoxicated intra peritoneally with diisopropylfluorophosphate were investigated. Pyridostigmine bromide (0.1 mg/kg) and atropine methylnitrate (20 mg/kg) were pretreated intramuscularly 30 min and 10 min, respectively, prior to diisopropylfluorophosphate (4-10 mg/kg) administration. Diisopropylfluorophosphate induced severe limbic seizures, early necrotic and delayed apoptotic brain injuries, and rapid astrocytic responses. The necrosis, which was closely related to seizure intensity, was observed as early as 1 hr after intoxication predominently in hippocampal pyramidal cells, cerebellar Purkinje cells and neurons in pyriform/entorhinal cortices, showing malacia of neurophils. In contrast, apoptosis started to appear 12 hr after intoxication in neurons in thalamus, amygdala and neocortex, and ephendymal cells surrounding the 4th ventricle. Since marked apoptosis was induced in rats exhibiting relatively-low seizure intensity, the degree of necrosis and apoptosis was shifted to each type of injury according to the seizure intensity. Activated astrocytes, observed within 1 hr along the limbic system, were suggested to affect the neural injury patterns by producing high level of nitric oxide. However, the distribution of activated astrocytes was not in parallel with those of necrotic or apoptotic injuries, implying that the astrocytic responses resulted from seizure activity rather than neural injuries. Furthermore, astrocytes in malacic tissues disappeared during the severe limbic seizures. Therefore, it would be one of the cautionary notes on the expression of glial fibrillary acidic protein in astrocytes as a biochemical marker of brain injuries following acute exposure to organophosphates.

• The Journal of Korean Academy of Sensory Integration
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• v.13 no.2
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• pp.75-84
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• 2015

Objective : The aim of this study was to provide mechanism information of a link between arousal and sensory modulation to increase understanding of neurophysiological study. Subject : Optimal arousal state of a child is an important issue in sensory integration therapy. Limbic system and reticular formation are related to sensory modulation by sensory input. Sensory inputs processes from reticular formation to cortex via ascending reticular activation system for moderate arousal. A lot of neurotransmitters such as cholinergic neurons and monoamin neurons help this processes. Mechanism of arousal was measured by functions of central nervous system (CNS) and autonomic nervous system (ANS) using objective tools such as an electroencephalogram (EEG) and electrodermal responses. Functions of CNS and ANS showed differences between normal children and children with disabilities. Optimal sensory input using sensory integration therapy for children with disabilities helps to act reticular formation, limbic system, and cortex and to maintain appropriate arousal. Conclusion : Such quantitative studies by using neurophysiological methods provide evidence for sensory integration therapy.

• Korean Journal of Oriental Medicine
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• v.2 no.1
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• pp.514-550
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• 1996

There are many theory in acupuncture mechanism, so we must know the detail contents. and then we can use the acupuncture as we know. the follow article will be helpful in this part. 1. Spinal cord are role in intermediate part in somatosensorypathway also in acupuncture stumulating tract 2. Acute pain pathway started in laminae I, V of gray colmn, next are the spinothalamic tract(trigeminal spinothalamic tract in above neck part) and then go to the specific thalamic nucleus. but chronic pain in laminae II, III, VI, VII, next are spinoreticular tract(trigeminal spinoreticular tract in the neck part) and finally to the nonspecific thalamic nucleus. 3. Thalamus is very important area in somatosensory stimuation including acupuncture stumulating sensory also as a pain control center. but except this, there are Hypothalamus, Limbic system Cerebral cortex and Cerebellum as intermediator. as we Know hypothalamus is related to the emotional analgesic system with a limbic system. 4. A ${\delta$ fiber has relationship in Acute, sharp and initial pain, contrary this C fiber is related with Chronic, dull and last pain. 5. In Acupuncture mechanism of pain analgesia, there are two theory, one is gate control theory as large fiber another is stimuation produced analgesia as small diameter fier. 6. In DNIC, the stimulation sources are mechanical, thermal, heating, pain and acupuncture stimulation etc. we call these as a Heterotopic Noxious Stimulation. 7. In DNIC, SRD(Subnucleus reticularis dorsalis)is core nucleus in pain imtermediated analgesic mechanism. 8. Takeshige insisted nonacupuncture point dependent analgesic mechanism and acupuncture point dependent analgesic mechanism. and protested that Stimulation acupuncture piing evoke blocking nomacupuncture point analgesic pathway.

• Journal of Sasang Constitutional Medicine
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• v.12 no.2
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• pp.17-33
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• 2000

Purpose of this study is to investigate the correlation between Sung-Jung' concept of Sasang Constitutional Medicine and Brain. So, After studying the meaning of Sung-Jung' concept of Sasang Constitutional Medicine, I made a comparative study through the structure, function, development of Brain. The conclusions were as follows. 1. Human's brain acts a rational, control his actions. and It manage human body's physiology and pathology. and It perceive his surroundings, express his emotion through comprehension, synthesis, judgement about information from various fields. and It's abnormality bring about a spiritual, bodily injury. Therefore, human's brain have many correlation with Sung-Jung' concept of Sasang Constitutional Medicine. 2. Neocortex' function have many correlation with Sung' concept of Hearing-Sight-Smell-Taste (聽視嗅味=sensation=a highly mental capacity) through Ear-Eye-Nose-Mouse(耳目鼻?). 3. Limbic-system'function have many correlation with Jung' concept of Sorrow-Anger-Pleasure-Joy(哀怒喜榮=emotion) through Lung-Spleen-Liver-Kidney(肺脾肝腎) 4. Brain-stem' function have many correlation with vitalistic concept through Qui of Sorrow - Anger - Pleasure - Joy(哀怒喜樂之氣)' rise and fall. 5. Relation of emotions and diseases through Limbic system and Autonomic nervous system have many correlation with relation of Sung-Jung and diseases of Sasang Constitutional Medicine 6. Left-hemisphere' function that has superior power of verbal, analysis, logicality, consideration have many correlation with tendency of Soeumin and Taeumin. and Right-hemisphere' function that has superior power of emotion, non-verbal, imagination, spatial perception have many correlation with tendency of Soyangin and Taeyangin.

• Korean Journal of Acupuncture
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• v.21 no.3
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• pp.77-88
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• 2004

Acupuncture has been shown to have therapeutic effects on many mental disorders such as depression, anxiety, and substance abuse in human and animal studies. Maternal separation (MS) is a risk factor in the development of mood-related disorders such as depression. This study investigated the effects of acupuncture during MS by evaluating locomotion as behavioral markers of depression and by observing changes in c-Fos expression in the limbic system (hippocampus, amygdala and cingulate cortex) to elucidate the mechanism of the therapeutic effect. The employed acupoint, Shinmun (HT7), has been clinically used to treat mental disorders. MS for 7 days beginning on postnatal day 14 induced a significant decrease in locomotion, while acupuncture treatment at acupoint HT7 resulted in a significant increase in locomotion. c-Fos immunoreactive cells in area dentate gyrus (DG) of the hippocampus were increased in the MS group, but significantly decreased in the acupuncture group. These findings suggest that acupuncture has an effect on the depression-like disorder caused by MS, possibly by modulating c-Fos expression in DC of the hippocampus.

• Proceedings of the IEEK Conference
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• 2003.07d
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• pp.1243-1246
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• 2003

It is known that structure of Human's brain information system is controlled by cerebral cortex mainly. Cerebral cortex is divided by sensory area, motor area and associated area largely. Sensory area takes part in information from environment and motor area is actuation by decision as associated area determined. It is possible to copy brain information system by input-output pattern. but there is difficulty in modeling of memorizing new information. Such action is performed by Limbic Lobe and Papez circuit which is controlled by intrinsic emotion. So we need of definition of emotion's role in decision. In this paper, we define roles of emotion in intrinsic decision using Dynamic Cognitive Maps(DCMs). The emotion is evaluated by outside information then intrinsic decision performed as how much emotion variated. The dynamic cognitive maps take part in emotion evaluating process.

• Science of Emotion and Sensibility
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• v.2 no.1
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• pp.1-25
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• 1999

The differentiation of emotions by means of psychophysiological measures has been only moderately successful so far. A major reason for this dilemma may be the lack of appropriate neurophysiological modeling for the various autonomic nervous system based measures being used in emotion research. The aim of the present article is to provide such a neurophysiological background for electrodermal activity which has been frequently used as an indicator of emotional processes. First, the literature is reviewd with respect to the usability of electrodermal measures as an indicators of emotion. second, the neurophysilogical sources of electrodermal phenomena in general are described. Electrodermal activity has different origins in the central nervous system, a limbic-hypothalamic source that dominates during negative emotions as opposed to a premotor and basal ganglia source being predominantly active during positive emotions. Panksepp's model of four basic emotive systems is adopted for demonstrating subcortical structures and pathways possibly involved in the elicitation of both kinds of electrodermal activity in comparison with cardiovascular in dicators of emotional processes.

• Journal of Electrical Engineering and Technology
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• v.8 no.3
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• pp.478-489
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• 2013

The controllability and stability of power systems can be increased by Flexible AC Transmission Devices (FACTs). One of the FACTs devices is Interline Power-Flow Controller (IPFC) by which the voltage stability, dynamic stability and transient stability of power systems can be improved. In the present paper, the convenient operation and control of IPFC for transient stability improvement are considered. Considering that the system's Lyapunov energy function is a relevant tool to study the stability affair. IPFC energy function optimization has been used in order to access the maximum of transient stability margin. In order to control IPFC, a Brain Emotional Learning Based Intelligent Controller (BELBIC) and PI controller have been used. The utilization of the new controller is based on the emotion-processing mechanism in the brain and is essentially an action selection, which is based on sensory inputs and emotional cues. This intelligent control is based on the limbic system of the mammalian brain. Simulation confirms the ability of BELBIC controller compared with conventional PI controller. The designing results have been studied by the simulation of a single-machine system with infinite bus (SMIB) and another standard 9-buses system (Anderson and Fouad, 1977).

• Science of Emotion and Sensibility
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• v.6 no.1
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• pp.47-53
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• 2003

This study is an experimental study about the relationship between EEG and personality dimensions. Subjects were 70 healthy undergraduate students (32 males, 38 females) The Korean version of Eysencks Personality Questionnaire-Revised (EPQ-R) were used. EEGs were recorded in two different conditions (eyes open and eyes closed). To obtain more tellable data, EEG recordings of subjects were replicated 6 weeks later. The analytical methods used in the present study rendered two coincident tendencies: Theta with neuroticism relationship in eyes closed condition, and alpha-delta with psychoticism relationship in eyes closed condition. These results generally support the theory of Robinson (2001) that delta, theta, and alpha waves are associated with activity of brainstem, limbic system, and thalamo-cortical arousal system, and that thalamo-cortical alpha system has inhibitory effects on brainstem delta system.