• 대한안과학회지
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• 제59권12호
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• pp.1114-1121
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• 2018

목적: 군날개 수술에서 자가윤부결막이식술 시 재발을 억제하기 위하여 시행한 추가 윤부절개술의 임상성적을 보고하고자 한다. 대상과 방법: 총 95안의 원발성군날개와 12안의 재발성 군날개 환자를 대상으로 자가윤부결막이식술 단독 및 추가 윤부절개술을 시행한 두 군으로 나누어 후향적 분석을 시행하였다. 추가 윤부절개술은 군날개를 제거한 각막윤부의 상부 및 하부경계에 각각 1 mm의 추가 절개를 하는 방법으로 시행하였다. 결과는 자가윤부결막이식술 단독 시행 39안, 추가 윤부절개술 시행 68안을 대상으로 비교 분석하였다. 결과: 전체 환자의 술 후 경과관찰 기간은 $29.6{\pm}10.5$개월이었으며, 자가윤부결막이식술 단독 시행 군에서는 $27.4{\pm}11.5$개월, 추가 윤부절개술 군에서는 $30.7{\pm}9.7$개월이었다. 재발은 자가윤부결막이식술 단독 시행 군에서는 6안(15.4%; 원발성 4안, 재발성 2안)이 있었으며, 추가 윤부절개술 군에서는 2안(2.9%; 원발성 1안, 재발성 1안)을 나타내었고, 두 군 간에 통계적으로 유의한 차이를 보였다(p<0.05). 재발이 나타날 때까지의 평균 기간은 자가윤부결막이식술 단독 시행 군에서 원발성 군날개인 경우 $6.3{\pm}3.4$개월, 재발성군날개인 경우 $4.3{\pm}2.5$개월이었으며, 추가 윤부절개술 군에서는 원발성 $12.1{\pm}2.6$개월, 재발성 $8.4{\pm}4.6$개월을 나타내었고, 두 군 간 통계적으로 유의한 차이를 보였다(p<0.05). 결론: 추가 윤부절개술은 자가윤부결막이식술을 단독 시행하였을 때보다 원발성 및 재발성 군날개 모두에서 재발 방지에 유용한 수술법이다.

• 한국임상수의학회지
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• 제37권5호
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• pp.282-285
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• 2020

A 14-year-old neutered-male Shih-Tzu was referred for glaucoma and hyphema accompanied by systemic hypertension. After topical corticosteroid and antiglaucoma medications, the left eye (OS) progressed phthisically, but ocular hypertension redevelop one-year-and-seven-months later. Suspected limbal melanoma developed in peripheral cornea/limbal sclera with heavily pigmented cornea OS. Ultrasound biomicroscopy and ocular ultrasonography differentiated ciliary body origin-heterogeneous mass from limbal mass. Persistent hyphema and pigmented cornea might obscure intraocular lesion and advanced diagnostic methods played a crucial role. Unlike the generally benign limbal melanoma, aggressive treatment was recommended for uveal tumor. Histopathology of enucleated OS confirmed malignant uveal melanoma with chronic hypertensive vasculopathy.

• Journal of Yeungnam Medical Science
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• 제24권2호
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• pp.243-251
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• 2007

비외상성의 수정체 이탈 환자에서 윤부 수정체절제술을 시행하는 경우, 초음파유화술 후 수정체낭 겸자를 이용하여 수정체낭을 모두 제거하고 앞유리체절제술을 시행하는 경우와 시행하지 않는 경우에 따라 시력예후 및 술후 합병증 발생에 미치는 영향에 대해 알아보고자 20명(33안)의 환자를 대상으로 술전 및 술후 합병증 발생에 대해 통계적으로 분석하였다. 앞유리체절제술을 시행한 I군(18명, 27안)과 앞유리체절제술을 시행하지 않은 II군(5명, 6안)으로 나누었으며, 술 후 두 줄 이상의 시력의 호전이 있는 경우를 호전의 지표로 삼았다. 술전과 비교하여 술후에 시력 호전이 있었던 경우가 I군은 27안 모두에서, II군은 6안중 5안에서 있었으나 두 군간에 유의한 차이는 없었다(p>0.05). 술후 합병증은 I군에서 인공수정체의 이탈이 4안(14.8%), 유리체 출혈이 2안(7.4%), 안내염이 1안(3.7%)에서 발생하였으며, II군에서 유리체 탈출이 1안(16.7%), 안압상승이 1안(16.7%)에서 발생하였으나, 두 군 모두에서 가장 시력을 위협하는 합병증인 망막박리는 발생하지 않았다. 비외상성 수정체 이탈의 치료로 수술적 치료의 적응증에 해당하는 경우 윤부 수정체절제술과 인공수정체 공막고정술을 시행하면 수술결과와 술후 합병증 면에서 좋은 수술술기가 될 것으로 사료되며, 앞유리체절제술은 유리체 탈출 등이 없다면 반드시 시행하지 않아도 수술결과에 영향을 주지 않을 것으로 생각된다.

• Journal of Veterinary Science
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• 제23권4호
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• pp.62.1-62.10
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• 2022

Background: The corneal and limbal morphology relevant to corneal epithelial maintenance in ten different species was examined using histological methods. Objectives: The presence of a Bowman's layer, limbal epithelial cell, and superficial stromal morphology was examined in the following species to evaluate the differences in corneal thickness and epithelium: Java sparrows, frogs, macaws, spoonbills, red pandas, penguins, horses, Dobermans, orangutans, and humans. Methods: Corneal sections (4 ㎛) were obtained from ten ocular globes from three different animal classes: Aves, Amphibia, and Mammalia. All sections were stained with hematoxylin and eosin and periodic acid-Schiff reaction. After microscopy, all stained slides were photographed and analyzed. Results: Significant morphological differences in the corneal and limbal epithelia and their underlying stroma between species were observed. The number of corneal epithelial cell layers and the overall corneal epithelial thickness varied significantly among the species. The presence of a Bowman's layer was only observed in primates (orangutans and humans). Presumed supranuclear melanin caps were noted in four species (orangutans, macaws, red pandas, and horses) in the limbal basal epithelial layer (putative site of corneal epithelial stem cells). The melanin granules covered the apex of the cell nucleus. Conclusions: Supranuclear melanin capping has been described as a process within the epidermis to reduce the concentration of ultraviolet-induced DNA photoproducts. Similarly, there may be a relationship between limbal stem cell melanin capping as a protective mechanism against ultra-violet radiation.

• 대한수의사회지
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• 제40권11호
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• pp.1003-1008
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• 2004

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2009년도 추계학술대회
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• pp.223-223
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• 2009

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XIII)
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• pp.318-318
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• 2003

• 한국임상수의학회지
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• 제16권2호
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• pp.506-508
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• 1999

An one-year-old, female pointer dog with conjunctival hyperemia, corneal opaque and ocular pain in right eye was referred to Veterinary Medical Teaching Hospital, Chungbuk National University. In the ophthalmic examination the worm was observed in anterior chamber, The heart worm antigen test was positive. A modified Knott's test was negative. The values of complete blood count and serum chemistry (TP, BUN, creatinine, AST, ALT, ALP, albumin, globuline) showed normal ranges. Any abnormality was not detected in the heart using a thoracic radiography and cardiac sonography. Therefore, this dog was diagnosed as ocular filariasis. The worm was removed by surgical incision through a limbus of cornea. The closure of limbal incision was sutured in a simple interrupted suture pattern with 6-0 silk and the eye was reinflated with sterile saline solution. Antibiotics and dexamethasone ophthalmic solution were applied to right eye every 24 hours for 7 days. To prevent latent filariasis, ivermectin was also administered on day 14 of operation. The heart worm antigen test on day 60 was negative. The dog was successfully cured.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2002년도 생물공학의 동향 (X)
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• pp.289-292
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• 2002

The corneal tissue consists of three layers : epithelium, stroma, and endothelium. Central cornea is a highly differentiated tissue whereas the limbus contains the epithelial stem cell. In the present study. we report the engineering of the three-dimensional reconstructed cornea derived from rabbit limbal epithelial and stromal cells. The differentiation degree of corneal stem cells were assessed in serum concentration and inoculation density of stromal cells. Optimal condition differentiation of corneal stem cells is achieved when 5% FBS was supplemented to culture medium and $1-2{\times}10^5$ cells/ml inoculation density of stromal cells.

• 한국임상수의학회지
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• 제19권4호
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• pp.415-417
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• 2002

To investigate the diurnal change of intraocular pressures(IOP) and compare of $Tono-pen^{XL}$ and Schi$\emptyset$tz tonometer, we measured the IOP in clinically normal eyes of dogs. To estimate the diurnal change of IOP, the measurements of IOP were taken with $Tono-pen^{XL}$ in 44 normal canine eyes. Two physicians measured the IOP through the central cornea and limbal cornea. To compare of two tonometers, a physician measured the IOP with both $Tono-pen^{XL}$ and Schi$\emptyset$tz (7.5 g) tonometer in 23 clinically normal eyes of dogs. Mean of lOP was 26.51 $\pm$ 6.91 mmHg and IOP was highest as 30.65 mmHg at a.m. 10, but not significantly different within physicians and corneal regions (p > 0.05). Correlation coefficient within two tonometers was too low.