• 수면정신생리
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• 제5권2호
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• pp.170-176
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• 1998

Nowadays light therapy is accepted practice in the treatment for Seasonal Affective Disorder. The author reviewed the practical aspects of light therapy, latest treatment research on optimal parameters of light therapy and the mechanisms of action of light therapy. Therapeutic efficacy of light therapy using light visors & dawn simulators has been suggested but further studies are needed to clarify the efficacy. The treatment most strongly supported by research studies is light therapy using a light box to administer bright white light (2500 lux for 2 hours or 10000 lux for 30 minutes). Although some patients may be selective responders to morning light exposure, the optimal timing of light exposure still remains controversial. In practice, generally the duration of exposure can be increased or decreased as necessary and also the timing of exposure can be splitted (e.g. AM/PM usage) if optimal response is obtained. For most, a positive response of light therapy is usually noted within $4{\sim}5\;days$ and optimal response is obtained within 2 weeks. Generally the relapse of symptom occurs within days of discontinuation of light therapy, so to prevent relapse, light therapy should be continued throughout the winter season for typical seasonal affective disorder. Side effects of light therapy appear to be mild and well tolerated. Several theories for the mechanisms of action of light therapy at the basis of seasonal affective disorder had been suggested but remain still controversial. Further studies on the optimal parameters and the mechanisms of light therapy help us to better understand and treat not only seasonal affective disorders but also chronobiological disorders and nonseasonal affective disorders.

• 수면정신생리
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• 제15권1호
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• pp.12-16
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• 2008

Light therapy (also called light treatment or phototherapy) involves scheduled exposure to bright artificial light. Evidence-based treatments for sleep disorders especially for circadian rhythm sleep disorders include light therapy and pharmacotherapy. In clinical practice, many of patients with sleep problems tend to impair circadian rhythmicity. Considering that light is the most potent entraining agent of circadian rhythm, careful use of light therapy can be recommended for patients with several kinds of sleep disorders. I briefly review the possible therapeutic mechanisms and clinical applications of light therapy, focusing on circadian sleep disorders.

• 여성건강간호학회지
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• 제21권3호
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• pp.197-206
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• 2015

Purpose: The purpose of this study was to examine the effects of light therapy on sleep disturbance and depression in climacteric women with menopausal symptoms. Methods: The research design was a nonequivalent control group pre test-post test design. Data were collected from September 29, 2013 to November 11, 2013. Participants included 17 climacteric women in an artificial light therapy group, 17 climacteric women in a sun light therapy group and 16 climacteric women in a control group. Measures consisted of the sleep disturbance, depression, melatonin, and serotonin. Results: There was a statistically significant difference of Korean Sleep Scale A (F=53.87, p<.001), and melatonin (F=31.19, p<.001) among three groups. There was a statistically significant difference of Self-Rating Depression Scale (F=121.86, p<.001), and serotonin (F=102.37, p<.001) among three groups. Conclusion: Artificial and sun light therapy can be applied as a supportive nursing intervention to subjects with sleep disturbance and depression in climacteric women with menopausal symptoms. Artificial and sun light therapy is expected to be a complementary alternative intervention for health management of the subjects with sleep disturbance and depression in climacteric women with menopausal symptoms.

• Journal of Acupuncture Research
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• 제32권3호
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• pp.211-220
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• 2015

Objectives : We report two cases of pressure ulcer patients to show the efficacy of treatment with acupuncture and Light Enitting Diode(LED) light therapy. Methods : We treated two pressure ulcer patients with acupuncture, LED light therapy, herbal medication and with a simple dressing. LED light with up to $4J/cm^2$ of energy irradiated the pressure ulcer site once a day for fifteen minutes. All patients received acupuncture treatment and simple dressing for wound care. We measured phase change of the pressure ulcer in terms of ulcer size, The National Pressure Ulcer Advisory Panel(NPUAP) stage and with the The Pressure Ulcer Scale for Healing(PUSH) tool(3.0). Results & Conclusions : In each of the two cases, pressure ulcer size and total score of the PUSH tool decreased and NPUAP stage was improved from II to I. This shows that acupuncture treatment and LED light therapy may have a considerable effect in healing on the pressure ulcer.

• Physical Therapy Rehabilitation Science
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• 제3권1호
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• pp.20-26
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• 2014

Objective: The low level lasers currently in the market vary in wavelength, dosage, and frequency. These devices are used with much different clinical pathology. Most notably, some studies claim that wounds heal faster with low level laser therapy due to the fact that bacteria commonly found in wounds are killed by laser light. Systemic and meta-analysis studies found the difficulty of comparison of numerous research studies because of differences in the intensities and frequencies of low level laser treatment (LLLT). The purpose of this study was to determine the effectiveness of LLLT on controlling bacterial growth. Design: Cross-sectional study. Methods: Variables included LLLT dosage and wavelength on 3 bacteria commonly seen in wounds, strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were used on commercially available 5.0-cm agar plates. Blue, green, and red, ultraviolet (UV) and infrared laser light sources were adjusted to either low or high intensity settings. Five Petri dishes at a time were placed directly beneath laser light sources with the exception of UV which was placed six inches below the suspended light and infrared which was placed directly on top of the Petri dish lid. Each group of five Petri dishes was irradiated for 15 minutes. Results: The results showed no effect of any of 9 different LLLT intensities or colors on bacteria growth compared to sham light. Conclusions: At least for claims of bacterial growth inhibition with LLLT, no support for this claim can be found here.

• The Journal of Korean Physical Therapy
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• 제15권2호
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• pp.146-156
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• 2003

Isolated rat thoracic aorta which is pharmacologically precontracted by phenylephrine induces photorelaxation when exposed to long wave length UV-light. The aim of the present study was to characterize the mechanism of UV-light induced by photorelaxation in the rat aorta. 1. UV light relaxed both endothelium-intact and -denuded rat aortic rings contracted by phenylephrine. The magnitude of relaxation on UV light was dependent on the exposure time and slightly greatly in endothelium-denuded rings than in endothelium-intact preparations. 2. L-NAME (10 nM - 100 $\mu$M) but not D-NAME completely inhibited the photorelaxation in a concentration dependent manner. 3. The UV-induced relaxation was inhibited by methylene blue (1 - 100 uM), and verapamil (100 nM), and removal of extracellular $Ca^{2+}$. In contrast, UV-light induced photorelaxation was potentiated by $N^{w}$-nitro-L-arginine (L-NNA) treatment. These results suggest that UV light-induced photorelaxation may be due to nitric oxide from exogenously administered L-arginine as well as endogenous nitric oxide donors such as amino acid and arginine derivatives

• 정신신체의학
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• 제8권1호
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• pp.103-109
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• 2000

저자들은 만성적인 피로감과 비특이적인 신체 증상을 나타내는 치료저항성 만성피로증후군 환자 1례를 경험하였다. 몇몇 연구들에서 만성피로증후군과 정서장애와의 관련성을 보고하고 있으나 계절성정서장에의 치료 도구로 인정받고 있는 만성피로증후군에서 광치료의 효용성에 대한 연구는 거의 없는 상태이다. 저자들은 2500lux의 광상자를 이용하여 본 증례의 환자에게 아침 광치료를 시도하여 임상적 증상의 호전을 경험하였기에 관련 문헌의 검토와 함께 보고하고자 한다.

• 수면정신생리
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• 제10권1호
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• pp.20-25
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• 2003

Many people suffer from chronic insomnia. Inappropriate sleep causes attention difficulties, decreased work efficiency, and increased traffic accidents and disasters. Evaluating the precise causes of insomnia prior to treatment is very important, because chronic insomnia can be a secondary symptom of other medical, psychiatric, and sleep disorders. Medication and behavior therapy are not exclusive of each other, and both treatments are beneficial to some patients, but currently many physicians and patients tend to be dependent only on medication. While long-term medication causes various degrees of dependency, tolerance, and withdrawal symptoms, behavior therapy has a stable effect over a long period. Behavior therapy is one of the most important treatment modalities for chronic insomnia. It shortens sleep latency, and decreases frequency of awakening during sleep. The rationale and practice of currently used behavior therapy and light therapy will be reviewed in this study.

• 수면정신생리
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• 제6권1호
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• pp.46-51
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• 1999

목 적 : 광치료는 계절성 기분장애, 약간의 비계절성 주요 우울장애 및 월경전우울증 등의 치료에 이용되고 있다. 저자들은 일중주기리듬의 장애가 병인론으로 제시되고 있는 월경전 불쾌기분 장애에 대한 광치료 효과를 평가하기 위하여 광치료의 임상시도를 하였다. 방 법 : DSM-IV의 월경전 불쾌기분장애 진단기준에 충족되는 4명의 환자에서 광박스(light box,Apolo bright lite III)를 이용한 저녁 광치료(6:30-8:00pm) 시도하였다. 결 과 : 연구대상은 광치료 후, 그 정도에는 차이가 있으나, 월경전기 증상과 더불어 우울기분과 불안이 감소하는 변화를 보였다. 본 연구는 임상시도로 연구대상이 적고, 위약 효과의 통제가 없으며, 증상 평가 방법에 있어 어려움 등 한계가 있으나, 이러한 변화는 특히 비정형 우울증상이 있는 환자에서 두드러졌으며, 신체증상보다는 심리증상에 보다 효과적인 결과를 보였다. 결 론 : 광치료는 월경전불쾌기분 장애 환자의 약물학적 치료에 대안적 방법으로 볼 수 있겠다. 향후 보다 많은 수의 환자를 대상으로, 위약대조 교차연구(아침, 저녁 광치료)가 필요할 것으로 사료된다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.480-480
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• 2007

This paper performed the basic study for developing the light therapy equipment for medical treatment. We developed the equipment for medical therapy using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity, frequency and so on. Especially, to control the light irradiation frequency, and to control the change of output value, TLC5941 was used. Control stage is divided into 4 step by program. Consequently, the current value could be controlled by the change of level in Continue Wave(CW) and the output of a high brightness LED could be controlled, stage by stage.