• 제목/요약/키워드: Life-long effects

검색결과 756건 처리시간 0.025초

압출성형시 환원제 첨가에 의한 밀가루 글루텐의 조직 변화와 단백질의 변성 (Effects of Reducing Agents on Textural Changes and Protein Modification in Extruded Wheat Gluten)

  • 고봉경
    • 동아시아식생활학회지
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    • 제6권2호
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    • pp.213-219
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    • 1996
  • Addition of reducing agents during extrusion markedly affected physical and chemical properties of wheat flour and gluten extrudates. Expansion at the die was increased for wheat flour and gluten extrudates. Organic materials containing sulfur were evaporated as a flavor from gluten at the die and total sulfur contents were decreased. Physical shape was different for gluten extrudates without reducing agents. It was difficult to form the long strand of gluten extrudate without cooling die. Hydroquinone accelerated cell breakdown and produced more irregular shape of extrudate. However, addition of cysteine decreased the cell breakdown and produced the long strand of gluten extrudates. Chemical reactions of reducing agents such as cysteine and hydroquinone were different for high content (<80%) of wheat gluten. It was assumed that reducing agents donated hydrogen to inhibit the formation of disulfide crosslinking, decreased the dough strength and produced the broken cell and irregular shape of extrudates. Whereas, cysteine reacted as a binder as well as reducing agent and formed long strands. The evidence of reaction of reducing agents was shown from the fact that non-protein disulfide was increased and protein disulfide was slightly decreased from cysteine added gluten extrudate.

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Nicotinamide Exerts Antioxidative Effects on Senescent Cells

  • Kwak, Ju Yeon;Ham, Hyun Joo;Kim, Cheol Min;Hwang, Eun Seong
    • Molecules and Cells
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    • 제38권3호
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    • pp.229-235
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    • 2015
  • Nicotinamide (NAM) has been shown to suppress reactive oxygen species (ROS) production in primary human fibroblasts, thereby extending their replicative lifespan when added to the medium during long-term cultivation. Based on this finding, NAM is hypothesized to affect cellular senescence progression by keeping ROS accumulation low. In the current study, we asked whether NAM is indeed able to reduce ROS levels and senescence phenotypes in cells undergoing senescence progression and those already in senescence. We employed two different cellular models: MCF-7 cells undergoing senescence progression and human fibroblasts in a state of replicative senescence. In both models, NAM treatment substantially decreased ROS levels. In addition, NAM attenuated the expression of the assessed senescence phenotypes, excluding irreversible growth arrest. N-acetyl cysteine, a potent ROS scavenger, did not have comparable effects in the tested cell types. These data show that NAM has potent antioxidative as well as anti-senescent effects. Moreover, these findings suggest that NAM can reduce cellular deterioration caused by oxidative damage in postmitotic cells in vivo.

뇌졸중 환자의 일상생활 수행능력, 신체상이 삶의 질에 미치는 영향: 대인관계 매개효과 중심 (Relationships of Activities of Daily Living and Body Image with Quality of Life in Stroke Patients: Mediating Effects of Interpersonal Relations)

  • 김민주;박효민
    • 근관절건강학회지
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    • 제28권2호
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    • pp.183-191
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    • 2021
  • Purpose: This study was conducted to identify factors associated with stroke patients' quality of life (QOL) and examine the mediating effects of interpersonal relations in the relationships of activities of daily living (ADL) and body image with QOL. Methods: In this study, 160 stroke patients were recruited from an outpatient clinic of a university hospital and rehabilitation clinic of a long-term care hospital. Participants completed a questionnaire which included sociodemographic characteristics, ADL, body image, interpersonal relation, and QOL. Descriptive statistics, t-tests, ANOVA, Pearson's correlation coefficients, multiple regression analysis, and process macro mediation analysis were conducted using SPSS. Results: The mean scores were 91.01 (range 6~100) for ADL, 61.19 (range 40~79) for body image, 87.53 (range 29~123) for interpersonal relations, and 186.67 (range 71~243) for QOL. Multiple regression analyses showed that ADL, body image, interpersonal relations, and participation in group activities after stroke were significantly associated with QOL among stroke patients (p<.05). There were no mediating effects of interpersonal relations in the relationships of ADL and body image with QOL (p>.05). Conclusion: This study showed that there is a need for physical, psychological, and social recovery to improve the QOL of stroke patients.

The Effects of Cynomorium songaricum on the Reproductive Activity in Male Golden Hamsters

  • Lee, Jee Soo;Oh, Hyun Ah;Kwon, Ji Young;Jeong, Min Ho;Lee, Jong Seok;Kang, Dong Won;Choi, Donchan
    • 한국발생생물학회지:발생과생식
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    • 제17권1호
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    • pp.37-43
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    • 2013
  • Cynomorium songaricum (CS) has been used in traditional Korean medicine in treating male impotence and sexual dysfunction. We investigated the effects of aqueous CS extract on the reproductive activity of golden hamsters whose spermatogenetic capacity is active in summer and inactive in winter. The animals were divided into 5 groups: long photoperiod (LP) control, short photoperiod (SP) control, and SP animals treated with low, middle, or high concentrations of CS. The animals were orally ingested with low (0.5 g/kg), middle (1.0 g/kg), or high (2.5 g/kg) concentrations of the aqueous extracts for 8 weeks on the daily basis. The control animals received the vehicle. As results, the LP control animals showed active testicular function but SP control animals displayed remarkably reduced testicular weights. The outcomes of the reproductive activity from low and middle concentrations of CS treatments were identical and marked as low dose. The consequences were a partial blocking of regressing activity by SP. On the other hand, the animals treated with high dose of CS extract showed remarkable significance in comparison to the SP control, indicative of a complete blocking effect of the CS on the regressing testes by SP. There were a dose-dependent effects of the CS on the sexual function. These results suggest that the CS extract promotes the male fertility by strengthening the spermatogenesis in the golden hamsters.

Development of Long-Term Storage Technology for Chinese Cabbage - Physiological Characteristics of Postharvest Freshness in a Cooler with a Monitoring and Control Interface

  • Lim, Ki Taek;Kim, Jangho;Chung, Jong Hoon
    • Journal of Biosystems Engineering
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    • 제39권3호
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    • pp.194-204
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    • 2014
  • Purpose: The aim of this study was to develop long-term storage technology for Chinese cabbage in order to extend the period of availability of freshly harvested products. The scope of the paper deals with the use of a cooler with a remote monitoring and control interface in conjunction with use of packaging film. Methods: A cooler with a real time monitoring system was designed as a low-temperature storage facility to control temperature and relative humidity (RH). The effects of storage in high-density polyethylene (HDPE) plastic boxes, 3% chitosan dipping solution, polypropylene film (PEF) with perforations, and mesh packaging bags on physiological responses were investigated. The optimal storage temperature and humidity for 120 days were below $0.5^{\circ}C$ and 90%, respectively. Physiological and biochemical features of cabbage quality were also analyzed: weight loss, texture, and sugar salinity, chlorophyll, reducing sugar, and vitamin C contents. Results: The cooler with a remote monitoring and control interface could be operated by an HMI program. A $0.5^{\circ}C$ temperature and 90% humidity could be remotely controlled within the cooler for 120 days. Postharvest freshness of Chinese cabbages could be maintained up to 120 days depending on the packaging method and operation of the remote monitoring system. In particular, wrapping the cabbages in PEF with perforations resulted in a less than a 5% deterioration in quality. This study provides evidence for efficient performance of plastic films in minimizing post-harvest deterioration and maintaining overall quality of cabbages stored under precise low-temperature conditions with remote monitoring and a control interface. Conclusions: Packaging with a modified plastic film and storage in a precisely controlled cooler with a remote monitoring and control interface could slow down the physiological factors that cause adverse quality changes and thereby increase the shelf life of Chinese cabbage.

권선형기기 On-line 부분방전 측정용 6-6kV급 Ceramic Coupler의 신뢰성 평가 (Evaluation of Reliability on the 6.6kV Class Ceramic Coupler for On-line Partial Discharge Measurement in Winding Machines)

  • 강동식;김용주;윤영호
    • 대한전기학회논문지:전기물성ㆍ응용부문C
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    • 제54권2호
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    • pp.69-75
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    • 2005
  • In order to improve the reliability of high voltage rotating machines and mold transformers, it is necessary to understand the breakdown mechanism and life assessment of the high voltage winding parts. Especially the on-line PD test provides the ability to monitor effects, such as slot discharge, internal discharge, and end-winding discharge without interrupting the electrical machines, this method has been proven the major testing technology. Capacitive couplers have been the most widely used sensors for the on-line partial discharge detection in rotating machines nowadays. This paper deals with the electrical characteristics and long-term reliability of a ceramic coupler(CC), which can be easily mounted into high voltage input terminal part, has been developed and tested to continuously measure PD activity during operating condition. This paper presents electrical characteristics (dielectric loss angle, capacitance, PD inception level, breakdown voltage, and frequency response bandwidth) and long-term life test result of the developed 6.6 kV class on-line ceramic coupling sensor. It was found that this sensor had good electrical characteristics to detect PD activity during the operating condition with its detection frequency band is between several and several tens MHz. Also, the voltage life of the 6.6kV class ceramic coupler was calculated over 60 years.

Long-term behavior of segmentally-erected prestressed concrete box-girder bridges

  • Hedjazi, S.;Rahai, A.;Sennah, K.
    • Structural Engineering and Mechanics
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    • 제20권6호
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    • pp.673-693
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    • 2005
  • A general step-by-step simulation for the time-dependent analysis of segmentally-erected prestressed concrete box-girder bridges is presented. A three dimensional finite-element model for the balanced-cantilever construction of segmental bridges, including effects of the load history, material nonlinearity, creep, shrinkage, and aging of concrete and the relaxation of prestressing steel was developed using ABAQUS software. The models included three-dimensional shell elements to model the box-girder walls and Rebar elements representing the prestressing tendons. The step-by-step procedure allows simulating the construction stages, effects of time-dependent deformations of materials and changes in the structural system of the bridges. The structural responses during construction and throughout the service life were traced. A comparison of the developed computer simulation with available experimental results was conducted and good agreement was found. Deflection of the bridge deck, changes in stresses and strains and the redistribution of internal forces were calculated for different examples of bridges, built by the balanced-cantilever method, over thirty-year duration. Significant time-dependent effects on the bridge deflections and redistribution of internal forces and stresses were observed. The ultimate load carrying capacities of the bridges and the behavior before collapse were also determined. It was observed that the ultimate load carrying capacity of such bridges decreases with time as a result of time-dependent effects.

청소년의 종교활동과 생활만족도에 관한 연구 - 개신교회에 출석하는 고등학생을 중심으로 (A Study on Adolescents' Religious Activities and Life Satisfaction)

  • 이성혜;전미경
    • 가정과삶의질연구
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    • 제24권3호
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    • pp.43-58
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    • 2006
  • The purpose of this study is to analysis the effects of religious activities on adolescents' life satisfaction. For this purpose, we surveyed the general trend of adolescents' religious activities and life satisfaction as well as life satisfaction according to demographical variables. In addition, this study analyzed adolescents' life satisfaction according to variables related to individual adolescents' religious activities and to parents' religious activities. The analyses of the results are as follows. First, since the childhood, adolescents have been participated in religious activities habitually or by enforcement or encouragement of their acquaintances. However, most adolescents think that the main purposes of their religious activities are a receiving grace and self-growing. So, they are willing to participate in worship service and spiritual training camp. Second, adolescents' life satisfaction was high when they got a high grade in school or they felt their health condition is good. The life satisfaction of adolescents who belong to economically high class families and whose fathers were college graduates or above is high. Third, the facts that effect on adolescent's life satisfaction are not how long they spend their time on religious activity, but the contents, motives and purposes of religious activities and satisfaction with religious activities. Fourth, adolescents' life satisfaction was high when their parents have same religion to them and their fathers participated in religious activities and their mothers did not participate in religious activities.

Effect of chlorella culture solution using animal liquid manure on improving seed germination in perennial ryegrass

  • Lee, Jin Woong;Choi, Min Soo;Seo, Un Kab;Ryoo, Jong Won
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
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    • pp.212-212
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    • 2017
  • This experiments were conducted to evaluate the influence of Chlorella culture solution on seed germination of perennial ryegrass seeds. Chlorella are known to contain different bioactive compounds. In present research work, Chlorella culture solution using liquid manure as medium have been used to study their effects on germination and root length. The study conducted a germination experiment in petri-dishes. Four treatments were compared: non-treated control treated with distilled water, Chlorella culture solution and Chlorella culture filtrate, and liquid manure. The germination percentage of perennial ryegrass seeds was highest in the Chlorella culture solution treatment. Days required for 50, 70% seed germination was the fast in Chlorella culture solution and the Chlorella culture filtrate treatment. Root length of perennial ryegrass seeds was long by 1~2cm in the Chlorella culture solution compared with no treated control. The germination index of perennial ryegrass seeds was high by 180~202% in the Chlorella culture solution treatment compared to no treatment. Chlorella culture solution and the Chlorella culture filtrate have shown stimulatory effects in germination and development of root. Use of Chlorella culture solution and the Chlorella culture filtrate can be recommended to farmers as a ecofriendly practice for better germination and growth. Present research work reveals that Chlorella contain certain growth promoting substances which enhances seed germination.

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Bitter Melon Seed Extract does not Alter Photoperiodic Effects on Reproduction of Male Golden Hamsters

  • Choi, Donchan;Lee, Su Ji;Lee, Min Hyuck;Lee, Dong Kyu
    • 한국발생생물학회지:발생과생식
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    • 제21권2호
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    • pp.215-221
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    • 2017
  • Bitter melon (Momordica charantia, MC) has been used in traditional Korean medicine in treating diabetes. In addition, some reports were emerged, showing the antifertility activities of MC in mammals. We investigated the effects of ethanolic MC extract on the reproductive activity of golden hamsters whose spermatogenetic capacity is controlled by their photoperiods. The animals were divided into 4 groups: long photoperiod (LP) control, short photoperiod (SP) control, and LP animals treated with MC. The animals were orally ingested with low (0.03 g/kg) or high (0.15 g/kg) concentrations of the ethanolic extracts for 8 weeks on the daily basis. The control animals received the vehicle. The animals were then mated with age-matched females, experienced pregnancy. As results, the LP control animals showed active large testes but SP control animals displayed remarkably reduced testes. The animals treated with both concentrations of MC extracts demonstrated large testes, indicating fertile activity as animals in LP. LP control animals had litters as expected, but SP controls had no litters at all. MC extract showed the same results as LP animals in generating offsprings. These results suggest that the MC extract does not change the photoperiodic influence on reproductive activity of male golden hamsters.