• Title/Summary/Keyword: Life component n

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Characteristics of Food Nutrition Components of Common Stalked Barnacle Pollicipes mitella (거북손(Pollicipes mitella)의 식품 영양성분 특성)

  • Moon, Soo-Kyung;Kim, In-Soo;Jeong, Bo-Young
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.6
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    • pp.862-866
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    • 2016
  • Common stalked barnacle Pollicipes mitella is a filter-feeding crustacean that attaches itself to the surfaces of rocks in the ocean intertidal zone. Pollicipes mitella is one of about a dozen species of goose barnacle that are gathered commercially for human consumption. In Portugal and Spain, they are a widely consumed and expensive delicacy known as "Percebes (Pollicipes pollicipes )". However, common stalked barnacle is less popular in Korea, and information on its nutritional component is not yet available. In the present study, we analyzed the proximate and fatty acid compositions and mineral content of common stalked barnacle (muscle and cirrus). The muscle and cirrus of common stalked barnacle were 15.1% and 14.3% protein, and 3.31% and 1.81% lipid, respectively. The prominent fatty acids in the muscle and cirrus were 22:6n-3 (docosahexaenoic acid, DHA), 16:0, 20:5n-3 (eicosapentaenoic acid, EPA), 18:0, 18:1n-9, 16:1n-7 and 14:0. In particular, common stalked barnacle contained high levels of n-3 polyunsaturated fatty acids, such as DHA (25.4-25.6%) and EPA (14.7-15.1%), and low levels of the n-6 fatty acid, 20:4n-6 (1.2-1.3%). Common stalked barnacle contained a relatively large amount of Zn (10-42 mg/100 g) in its muscle and cirrus.

k-OUT-OF-n-SYSTEM WITH REPAIR : T-POLICY

  • Krishnamoorthy, A.;Rekha, A.
    • Journal of applied mathematics & informatics
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    • v.8 no.1
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    • pp.199-212
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    • 2001
  • We consider a k-out-of-n system with repair under T-policy. Life time of each component is exponentially distributed with parameter $\lambda$. Server is called to the system after the elapse of T time units since his departure after completion of repair of all failed units in the previous cycle or until accumulation of n-k failed units, whichever occurs first. Service time is assumed to be exponential with rate ${\mu}$. T is also exponentially distributed with parameter ${\alpha}$. System state probabilities in finite time and long run are derived for (i) cold (ii) warm (iii) hot systems. Several characteristics of these systems are obtained. A control problem is also investigated and numerical illustrations are provided. It is proved that the expected profit to the system is concave in ${\alpha}$ and hence global maximum exists.

Deformation and Life Evaluation of PC Plastic Materials Subjected to Repeated Impact Loads (반복적인 충격하중을 받은 PC 플라스틱 재료의 변형 및 수명 평가)

  • Lee, Jin-Kyung
    • Journal of the Korean Society of Industry Convergence
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    • v.23 no.4_2
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    • pp.611-616
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    • 2020
  • Polycarbonate (PC) materials having electrical insulation properties, are thermoplastic material and are easily processed, have excellent strength and heat resistance characteristics, and also have transparent and hard characteristics. In this study, we tried to derive the ε-N curve of strain-life, which shows the relationship between the strain characteristics and the life of the material when repeated impact loads are applied to the PC plastic material. As the impact load increased to 3.0kg, 4.0kg, 5.0kg, and 6.0kg, the strain also increased linearly to 0.033, 0.041, 0.046, and 0.055. At 3.0kg of mass impact, the test piece broke with 12000 impact cycles, 8400 times at 3.5kg, 7400 times at 4.0kg, 6600 times at 4.5kg, 4700 times at 5.0kg, 3000 times at 5.5kg, and 1000 times at 6.0kg. The number of fractures exponentially decreased as the load gradually increased. Using these results, an ε-N curve for PC plastic was derived.

The relationship between disability and clinical outcomes in maintenance dialysis patients

  • Kang, Seok Hui;Do, Jun Young;Kim, Jun Chul
    • Journal of Yeungnam Medical Science
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    • v.38 no.2
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    • pp.127-135
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    • 2021
  • Background: Dialysis patients are prone to having disabilities. We aimed to evaluate the association between disability and various clinical outcomes in Korean dialysis patients. Methods: This study consisted of 1,615 dialysis patients from 27 centers. We evaluated disability by using four questions on the activities of daily living (ADLs) concerning whether help was needed for feeding, dressing/undressing, getting in/out of bed, or taking a bath/shower. We divided the patients into three groups: no disability (Non-D, none of the four ADL domains required help; n=1,312), mild disability (Mild-D, one ADL domain required some/full help; n=163), or moderate to severe disability (MS-D, two or more ADL domains required some/full help; n=140). We evaluated falls, frailty, health-related quality of life (HRQoL), mortality, and hospitalization. Results: The numbers of participants with a fall during the last 1 year were 199 (15.2%), 42 (25.8%), and 44 (31.4%) in the Non-D, Mild-D, and MS-D groups, respectively (p<0.001). The numbers of participants with frailty in the Non-D, Mild-D, and MS-D groups were 381 (29.0%), 84 (51.5%), and 93 (66.4%), respectively (p<0.001). In both univariate and multivariate analyses, the physical component scale and mental component scale scores decreased as the grade of disability increased (p<0.001 for both scores). Hospitalization-free survival rate at 500 days was 64.2%, 56.7%, and 51.1% in the Non-D, Mild-D, and MS-D, respectively (p=0.001 for trend). Patient survival rate at 500 days was 95.3%, 89.5%, and 92.3% in the Non-D, Mild-D, and MS-D, respectively (p=0.005 for trend). Conclusion: Disability was associated with falls, frailty, HRQoL scales, and survival trends in Korean dialysis patients.

Isolation and Structure Determination of Antioxidants from the Root of Paeonia lactiflora (작약(芍藥)(Paeonia lactiflora) 뿌리로부터 항산화활성 물질의 분리)

  • Bang, Myun-Ho;Song, Jung-Choon;Lee, Sang-Yang;Park, Nam-Kyu;Baek, Nam-In
    • Applied Biological Chemistry
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    • v.42 no.2
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    • pp.170-175
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    • 1999
  • On the purpose of development of novel antioxidative compounds from natural sources, 38 plants expected to show antioxidant activity have been examined concerning DPPH radical scavenging activity. Among them, thirteen plants, including Paeoniae radix, the root of Paeonia lactiflora, exhibited the activity. In order to isolate active component, the root was extracted in 80% aqueous MeOH and solvent fractionated with EtOAc, n-BuOH and water, successively. Silica gel column chromatographies of the EtOAc and n-BuOH fraction exhibiting antioxidant activity. were repeatedly carried out with monitoring by DPPH assay to afford three active compounds. On the basis of spectral data and the chemical characteristics, the structures of the compounds were determined as (+)-catechin, $1,2,3,4-tetragalloyl-6-digalloyl-{\beta}-D-glucose$ and $1,2,3,4,6-penta-galloyl-{\beta}-D-glucose$.

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Influence of the Surface Energetics on flotation Process - Importance of the Surface Energy and Polarity of Solid Particles in Flotation Efficiency - (부유부상 공정에 있어서 표면 에너지의 역할 - 부유부상 효율에 있어 고형 입자의 표면 에너지 및 극성성분의 중요성 -)

  • Lee, Hak-Rae;Park, Il;Lee, Yong-Min;Lee, Jin-Hee;Cho, Joong-Yeon;Han, Sin-Ho
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.34 no.3
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    • pp.1-8
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    • 2002
  • The object of this study was to determine the surface energy of hydrophobically modified micro-crystalline cellulose (MCC) with AKD and evaluate the effect of surface energy of the solid particles dispersed in aqueous medium on flotation efficiency. Especially to eliminate the complication derives from the diverse parameters of solid particles including particle size, type, etc. MCC's modified with AKD have been used. The surface energy Parameters were calculated from advancing contact angles of apolar and polar liquids on MCC pellets using the Lifshitz-van der Waals acid-base (LW:AB) approach. Total surface energy of hydrophobic MCC ranged from 46.19 mN/m to 48.60 mN/m. The contribution of the acid-base components to the total surface energy ranged form 13% to 17% for hydrophobic MCC's. The effect of surface characteristics on the flotation efficiency was evaluated. It was shown that there exist critical values of surface energies to increase flotation efficiency. Total surface energy and polar component of solid particles should be lower than 47 mN/m and 7 mN/m, respectively, for effective removal in the flotation process.

Preparation of Selenium-enriched Bifidobacterium Longum and its Effect on Tumor Growth and Immune Function of Tumor-Bearing Mice

  • Yin, Yan;Wang, Rong-Rong;Wang, Yan;Wang, Jian-Jun;Xu, Gen-Xing
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3681-3686
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    • 2014
  • In this study, we demonstrated selenium (Se) accumulation in Bifidobacterium longum strain (B. longum) and evaluated the effect of Se-enriched B. longum (Se-B. longum) on tumor growth and immune function in tumor-bearing mice. Analysis using high-performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) revealed that more than 99% of Se in Se-B. longum was organic, the main component of which was selenomethionine (SeMet). In the in vivo experiments, tumor-bearing mice (n=8) were orally administrated with different doses of Se-B. longum alone or combined with cyclophosphamide (CTX). The results showed that the middle and high dose of Se-B. longum significantly inhibited tumor growth. When Se-B. longum and CTX were combined, the antitumor effect was significantly enhanced and the survival time of tumor-bearing mice (n=12) was prolonged. Furthermore, compared with CTX alone, the combination of Se-B. longum and CTX stimulated the activity of natural killer (NK) cells and T lymphocytes, increasing the levels of interleukin-2 (IL-2) and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), and the leukocyte count of H22 tumor-bearing mice (n=12).

A Study on Fatigue Crack Growth and Life Modeling using Backpropagation Neural Networks (역전파신경회로망을 이용한 피로균열성장과 수명 모델링에 관한 연구)

  • Jo, Seok-Su;Ju, Won-Sik
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.24 no.3 s.174
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    • pp.634-644
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    • 2000
  • Fatigue crack growth and life is estimated by various fracture mechanical parameters but affected by load, material and environment. Fatigue character of component without surface notch cannot be e valuated by above-mentioned parameters due to microstructure of in-service material. Single fracture mechanical parameter or nondestructive parameter cannot predict fatigue damage in arbitrary boundary condition but multiple fracture mechanical parameters or nondestructive parameters can Fatigue crack growth modelling with three point representation scheme uses this merit but has limit on real-time monitoring. Therefore, this study shows fatigue damage model using backpropagatior. neural networks on the basis of X-ray half breadth ratio B/$B_o$ fractal dimension $D_f$ and fracture mechanical parameters can predict fatigue crack growth rate da/dN and cycle ratioN/$N_f$ at the same time within engineering estimated mean error(5%).

N-terminal formylmethionine as a novel initiator and N-degron of eukaryotic proteins

  • Kim, Jeong-Mok
    • BMB Reports
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    • v.52 no.3
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    • pp.163-164
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    • 2019
  • The ribosomal synthesis of proteins in the eukaryotic cytosol has always been thought to start from the unformylated N-terminal (Nt) methionine (Met). In contrast, in virtually all nascent proteins in bacteria and eukaryotic organelles, such as mitochondria and chloroplasts, Nt-formyl-methionine (fMet) is the first building block of ribosomal synthesis. Through extensive approaches, including mass spectrometric analyses of the N-termini of proteins and molecular genetic techniques with an affinity-purified antibody for Nt-formylation, we investigated whether Nt-formylated proteins could also be produced and have their own metabolic fate in the cytosol of a eukaryote, such as yeast Saccharomyces cerevisiae. We discovered that Nt-formylated proteins could be generated in the cytosol by yeast mitochondrial formyltransferase (Fmt1). These Nt-formylated proteins were massively upregulated in the stationary phase or upon starvation for specific amino acids and were crucial for the adaptation to specific stresses. The stress-activated kinase Gcn2 was strictly required for the upregulation of Nt-formylated proteins by regulating the activity of Fmt1 and its retention in the cytosol. We also found that the Nt-fMet residues of Nt-formylated proteins could be distinct N-terminal degradation signals, termed fMet/N-degrons, and that Psh1 E3 ubiquitin ligase mediated the selective destruction of Nt-formylated proteins as the recognition component of a novel eukaryotic fMet/N-end rule pathway, termed fMet/N-recognin.

Apoptosis in Cancer - An Update

  • Sankari, S. Leena;Masthan, K.M.K.;Babu, N. Aravindha;Bhattacharjee, Tathagata;Elumalai, M.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.4873-4878
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    • 2012
  • Apoptosis is programmed cell death which is essential for development and survival of living organisms. It is a sequentially regulated suicidal programme where cells activate certain enzymes which dissolute their own nuclear component and various protein component of nucleus and cytoplasm. Disturbance of this regulatory pathway may lead to various diseases like autoimmune diseases, neurodegenerative diseases and cancers. The potential mechanisms of apoptosis and its role in cancer are discussed. The ability of apoptosis to modulate the life or death of a cell is also recognized for its immense therapeutic potential. Understanding the mechanisms from this review will give us better insight to the pathogenesis of various diseases including cancer and will open new horizons to therapeutic approaches.