• Journal of the Korean BIBLIA Society for library and Information Science
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• v.32 no.1
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• pp.415-442
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• 2021

This study analyzed YouTube beauty videos that focus on makeup for teens, based on the assumption that the main viewers of the videos are teens. Through looking at the interaction between beauty information providers and receivers, communication among information receivers, and the way people participate in comment thread, the study examined how teens engage in social media. Many teens who posted comments on YouTube beauty videos praised and envied the beauty of beauty gurus, and tried to connect with them. The comment thread shows that teens answered to each other's questions on makeup tips, shared thoughts and experiences on issues around teen wearing makeup, which helped them build a sense of community, and broaden their views on the way of life. Also observed was power dynamics among youth, such as lecturing or verbal abuse against children and pre-teens by older teens.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.34 no.3
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• pp.109-134
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• 2023

The purpose of this study is to identify the current status of institutional research data repositories in the field of science and technology and to suggest ways to activate them. The study conducted literature research, case analysis, and interviews with repository managers both domestically and internationally. The study suggested strategies with a focus on establishing repository regulations and policies, improving awareness of research data sharing, and enhancing research data quality management. First, in terms of repository regulations and policy establishment, it was considered necessary to promote the status of the National R&D Information Processing Standards, a regulation related to research data, and clarify repository basis regulations. Second, to enhance awareness of research data sharing, the need for comprehensive research data education and the identification of exemplary cases were suggested. Third, in terms of strengthening research data quality management, the need for preparation for interaction between researchers-persons in charge-committees, standardization work, and long-term preservation was suggested.

• Journal of Korean Library and Information Science Society
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• v.54 no.2
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• pp.155-178
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• 2023

Due to the rapid advancement of information technology and changes in the reading environment, the readers' advisory services provided by public libraries are facing challenges and opportunities. Recognizing the need for public libraries to respond and propel their services forward, this study analyzed the current status of online readers' advisory services offered by public libraries in Korea and discusses areas that require improvement. To achieve this, the study analyzed the online readers' advisory services in 50 public libraries located in Seoul and six metropolitan cities (Incheon, Daejeon, Daegu, Gwangju, Busan, and Ulsan) across seven categories. These categories encompass various aspects, such as announcing reading programs and new books, identifying and addressing reader needs, developing content by librarians, generating content by readers, providing guidance on external reading information, connecting with professional book review databases and online websites, and utilizing social media services. Through this analysis, the study identified areas for improvement to enhance online readers' advisory services in public libraries and ultimately improve reader satisfaction. It suggested enhancing activities such as librarians' book recommendations and reviews for individual readers, reader participation, and interaction.

• Journal of the Korean Society for Library and Information Science
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• v.56 no.1
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• pp.425-447
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• 2022

The purpose of this study is to introduce the Theory of Information Worlds which analyzes information behaviors in the social perspective. This study analyzed dissertations using the theory to provide the understanding of the theory and suggest theoretical implications. The theory was developed by Burnett and Jeager in 2008, and since then it was applied in 14 dissertations. Key concepts of the theory include social norms, social types, information value, information behavior, and boundaries. These concepts are intervened in the process of creation and control of behavior through interaction each other. Qualitative research was adopted in more research rather than quantitative research; especially interview and content analysis were applied. It is expected that the spectrum of information behavior research in Korea is broaden and deeper through this study.

• 한국균학회소식:학술대회논문집
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• 2014.10a
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• pp.13-13
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• 2014

Species belonging to the genus Fusarium are widely distributed and cause diseases in many plants. Isolation of fungal strains from air or cereals is necessary for disease forecasting, disease diagnosis, and population genetics [1]. Previously we showed that Fusarium species are resistant to toxoflavin produced by the bacterial rice pathogen Burkholderia glumae while other fungal genera are sensitive to the toxin, resulting in the development of a selective medium for Fusarium species using toxoflavin [2]. In this study, we have tried to elucidate the resistant mechanism of F. graminearum against toxoflavin and interaction between the two pathogens in nature. To test whether B. glumae affects the development of F. graminearum, the wild-type F. graminearum strains were incubated with either the bacterial strain or supernatant of the bacterial culture. Both conditions increased the conidial production five times more than when the fungus was incubated alone. While co-incubation resulted in dramatic increase of conidial production, conidia germination delayed by either the bacterial strain or supernatant. These results suggest that certain factors produced by B. glumae induce conidial production and delay conidial germination in F. graminearum. To identify genes related to toxoflavin resistance in F. graminearum, we screened the transcriptional factor mutant library previously generated in F. graminearum [3] and identified one mutant that is sensitive to toxoflavin. We analyzed transcriptomes of the wild-type strain and the mutant strain under either absence or presence of toxoflavin through RNAseq. Expression level of total genes of 13,820 was measured by reads per kilobase per million mapped reads (RPKM). Under the criteria with more than two-fold changes, 1,440 genes were upregulated and 1,267 genes were down-regulated in wild-type strain than mutant strain in response to toxoflavin treatment. A comparison of gene expression profiling between the wild type and mutant through gene ontology analysis showed that genes related to metabolic process and oxidation-reduction process were highly enriched in the mutant strain. The data analyses will focus on elucidating the resistance mechanism of F. graminearum against toxoflavin and the interaction between the two pathogens in rice. Further evolutionary history will be traced through figuring out the gene function in populations and in other filamentous fungi.

• Journal of Korea Multimedia Society
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• v.20 no.8
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• pp.1258-1270
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• 2017

'Semantic gap' has been a year-old problem in automatic video summarization, which refers to the gap between semantics implied in video summarization algorithms and what people actually infer from watching videos. Using the external EEG bio-feedback obtained from video watchers as a solution of this semantic gap problem has several another issues: First, how to define and measure noises against ERP waveforms as signals. Second, whether individual differences among subjects in terms of noise and SNR for conventional ERP studies using still images captured from videos are the same with those differently conceptualized and measured from videos. Third, whether individual differences of subjects by noise and SNR levels help to detect topic-irrelevant shots as signals which are not matched with subject's own semantic topical expectations (mis-match negativity at around 400m after stimulus on-sets). The result of repeated measures ANOVA test clearly shows a 2-way interaction effect between topic-relevance and noise level, implying that subjects of low noise level for video watching session are sensitive to topic-irrelevant visual shots, while showing another 3-way interaction among topic-relevance, noise and SNR levels, implying that subjects of high noise level are sensitive to topic-irrelevant visual shots only if they are of low SNR level.

• Journal of KIISE:Software and Applications
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• v.26 no.9
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• pp.1052-1060
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• 1999

이제까지 비디오 데이타베이스를 모델링하기 위한 많은 연구들이 수행되었지만 그 모든 모델들에서 다루는 비디오 데이타는 사용자의 개입이 없을 때 항상 미리 정의된 순서로 보여진다는 점에서 정적 데이타 모델로 간주될 수 있다. 주문형 뉴스 서비스, 주문형 비디오 서비스, 디지털 도서관, 인터넷 쇼핑 등과 같이 최신 비디오 정보 서비스를 제공하는 비디오 데이타베이스 응용들에서는 빈번한 비디오 편집이 요구되는데 실시간 처리가 바람직하다. 이를 위해서 기존의 비디오 데이타 내용이 변경되거나 새로운 비디오 데이타가 생성되어야 하지만 이제까지의 비디오 데이타 모델에서는 이러한 비디오 편집 작업이 일일이 수작업으로 수행되어야만 했다. 본 논문에서는 비디오 편집에 드는 노력을 줄이기 위해서 객체지향 데이타 모델에 기반하여 DVID(Dynamic Video Object Data Model)라는 동적 비디오 객체 데이타 모델을 제안한다. DVID는 기존의 정적 비디오 객체뿐만 아니라 사용자의 개입없이도 비디오의 내용을 비디오 데이타베이스로부터 동적으로 결정하여 보여주는 동적 비디오 객체도 함께 제공한다.Abstract A lot of research has been done on modeling video databases, but all of them can be considered as the static video data model from the viewpoint that all video data on those models are always presented according to the predefined sequences if there is no user interaction. For some video database applications which provides with up-to-date video information services such as news-on-demand, video-on-demand, digital library, internet shopping, etc., video editing is requested frequently, preferably in real time. To do this, the contents of the existing video data should be changed or new video data should be created, but on the traditional video data models such video editing works should be done manually. In order to save trouble in video editing work, this paper proposes the dynamic video object data model named DVID based on object oriented data model. DVID allows not only the static video object but also the dynamic video object whose contents are dynamically determined from video databases in real time even without user interaction.

• Journal of Microbiology and Biotechnology
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• v.12 no.5
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• pp.807-812
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• 2002

In order to analyze the cellular proteins which interact with core protein of hepatitis C virus (HCV), a yeast two-hybrid screening technique was employed. A carboxyl terminus truncated core protein, which contained amino acid residues from the 1st to 120th, was used as a bait to screen cellular proteins. The expression library prepared from HeLa cell was screened and 400 positive clones were selected. The 75 clones from the positive clones were sequenced and analyzed by undergoing the Blast search. Interestingly, 7 out of the 75 clones encoded E7 antigen of human papilloma virus (HPV). We studied in detail the Interaction between the truncated version of HCV core and E7 antigen in vitro. The core$_{120}$ protein expressed in chimeric form with G57 was able to bring down the E7 protein of HPV type 18 expressed in bacteria. It is therefore suggested that the core of HCV might affect the interaction between E7 and a normal cellular tumor suppressor, known as Rb protein.

• The Plant Pathology Journal
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• v.23 no.4
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• pp.281-286
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• 2007

Interactions between viral proteins and host proteins are essential for virus replication. Especially, translation of viral genes completely depends on the host machinery. In potyviruses, interactions of genome-linked viral protein (VPg) with host translation factors including eIF4E, eIF(iso)4E, and poly(A)-binding protein (PABP) has previously been characterized. In this study, we investigated interactions between Soybean mosaic virus (SMV) viral proteins and host translation factors by yeast two-hybrid system. SMV VPg interacted with eIF4E, eIF(iso)4E, and PABP in yeast two-hybrid system, while SMV helper component proteinase (HC-pro) interacted with neither of those proteins. The interaction between SMV NIb and PABP was also detected. These results are consistent with those reported previously in other potyviruses. Interestingly, we found reproducible and specific interactions between SMV coat protein (CP) and PABP. Deletion analysis showed that the region of CP comprising amino acids 116 to 206 and the region of PABP comprising amino acids 520 to 580 are involved in CP/PABP interactions. Soybean library screening with SMV NIb by yeast two-hybrid assay also identified several soybean proteins including chlorophyll a/b binding preprotein, photo-system I-N subunit, ribulose 1,5-biphosphate carboxylase, ST-LSI protein, translation initiation factor 1, TIR-NBS type R protein, RNA binding protein, ubiquitin, and LRR protein kinase. Altogether, these results suggest that potyviral replicase may comprise a multi-protein complex with PABP, CP, and other host factors.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.3
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• pp.321-329
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• 2018

It was recently reported that the $C_{max}$ and AUC of rosuvastatin increases when it is coadministered with telmisartan and cyclosporine. Rosuvastatin is known to be a substrate of OATP1B1, OATP1B3, NTCP, and BCRP transporters. The aim of this study was to explore the mechanism of the interactions between rosuvastatin and two perpetrators, telmisartan and cyclosporine. Published (cyclosporine) or newly developed (telmisartan) PBPK models were used to this end. The rosuvastatin model in Simcyp (version 15)'s drug library was modified to reflect racial differences in rosuvastatin exposure. In the telmisartan-rosuvastatin case, simulated rosuvastatin $C_{maxI}/C_{max}$ and $AUC_I/AUC$ (with/without telmisartan) ratios were 1.92 and 1.14, respectively, and the $T_{max}$ changed from 3.35 h to 1.40 h with coadministration of telmisartan, which were consistent with the aforementioned report ($C_{maxI}/C_{max}$: 2.01, $AUC_I/AUC$:1.18, $T_{max}:5h{\rightarrow}0.75h$). In the next case of cyclosporine-rosuvastatin, the simulated rosuvastatin $C_{maxI}/C_{max}$ and $AUC_I/AUC$ (with/without cyclosporine) ratios were 3.29 and 1.30, respectively. The decrease in the $CL_{int,BCRP,intestine}$ of rosuvastatin by telmisartan and cyclosporine in the PBPK model was pivotal to reproducing this finding in Simcyp. Our PBPK model demonstrated that the major causes of increase in rosuvastatin exposure are mediated by intestinal BCRP (rosuvastatin-telmisartan interaction) or by both of BCRP and OATP1B1/3 (rosuvastatin-cyclosporine interaction).