• Asian Pacific Journal of Cancer Prevention
• /
• 제15권3호
• /
• pp.1465-1470
• /
• 2014

Inhibitor of DNA binding 1 (Id1) plays an important role in genesis and metastatic progression of prostate cancer. We previously reported that down regulation of Id1 by small interfering RNA could inhibit the proliferation of PC3 cells and growth of its xenografted tumors. Curcumin, the active ingredient of turmeric, has shown anti-cancer properties via modulation of a number of different molecular regulators. Here we investigated whether Id1 might be involved in the anti-cancer effects of curcumin in vivo and in vitro. We firstly confirmed that curcumin inhibited cell viability in a dose-dependent fashion, and induced apoptosis in PC3 cells, associated with significant decrease in the mRNA and protein expression of Id1. Similar effects of curcumin were observed in tumors of the PC3 xenografted mouse model with introperitoneal injection of curcumin once a day for one month. Tumor growth in mice was obviously suppressed by curcumin during the period of 24 to 30 days. Both mRNA and protein levels of Id1 were significantly down-regulated in xenografted tumors. Our findings point to a novel molecular pathway for curcumin anti-cancer effects. Curcumin may be used as an Id1 inhibitor to modulate Id1 expression.

• 복식
• /
• 제37권
• /
• pp.133-148
• /
• 1998

This study presents the aspects and changing process of the habiliment from the National Liberation up to now by analyzing the articles of costume found in$\ulcorner$Maeil Shinmun$\lrcorner$from Jan. 1. 1946 to Dec. 31. 1996. In the period of 1946~1959, the political and economic conditions through the National Liberation and Korean war deteriorated and the interest in costumes were weakened. But the economic recovery and social stability in the middle of the 50's made the lost interest in costumes increase. From 1960 to 1969, the high economic growth was achieved by“Five year plans for Economic Development”and the progress of mass media, transportation, communication and education brought western culture to our society. It spread rapidly and changed the way of life and the sence of value. These phenomenon led to a great transition on the Korean costume culture in the 60's In 1970~1979, the articless of costume made a change from the 60's, which focused on women's wear, and tuned to one including general costumes not only women's wear but also men's wear due to the women's social roles, the unisexmode and diverse costume. In 1980~1989, the growth of the consumption, the banning of the school uniform, Asian Games(1986) and Olympic games(1988) caused the high qualification, personalization and diversification in the fashion industry. Further more, the traditional-oriented trend with korean culture was emphasized. It pursued the modernization of the traditional Korean Costume, Hanbok, to introduce the unique Korean Beauty. From 1990 to 1996, in the era of international-ization and open door policy, the competition of nations became intense and the comprehention about environmental destruction highlingted the concerns on ecology. The recognition of environmental protection and recycling were reflected in the fashion. It prevailed that the pursuit of personalization,. diverse style, practicality and the fashion leader called generation appeared.

• 수산경영론집
• /
• 제15권2호
• /
• pp.1-23
• /
• 1984

In fisheries financing before the liberation of Korea, the accommodation of funds through modern monetary facilities was hardly benefited to most of small-scale Korean fishermen except Japanese fishermen living in Korea and some large-scale Korean fishermen. In fact, since Korean economy was only in the beginning stage of capitalism free from natural economy in the end of Yi Dynasty, it was natural that the supply of funds should be lacked. But after the opening of ports in Korea, the external shapes in Korean society were slowly changed according as heteronomous modernization was pushed forward by means of western capitalism and the intentional invasion of Japanese was gradually weighed. Thus all kinds of fishing equipments and technique were developed by dint of modernization, and modern monetary facilities also came into being. But most of Korean fishermen were hardly benefited by modern monetary facilities. Fishermen who were faced with destitution of funds were forced to rely upon high interest loans in order to make a living or maintain fisheries, and they were severely exploited by usurers. The situation was the same in the period of Japanese imperialism. Japanese felt the necessity of advancement of Korean fisheries and established fisheries institution suitable for all kinds of colonial fisheries policy toward Korea so that they could build up the foundation according to the development of capitalism and carry out the Russo-Japanese War and the Sino-Japanese War. There were a series of bottlenecks in financing on account of the deficiency of fisheries institution in the beginning of Japanese imperialism, but the financial pressure was lightened because the arrangement of institution greatly contributed to the smoothness of fisheries financing in the latter part of it. Despite such improvement of financing, the benefit of funds could not equally reach to all the fishermen. It only reached to Japanese fishermen living in Korea and some large scale Korean fishermen. Thus most of korean fishermen could not free themselves from destitution of financing and the pressure of high interest loans. This phenomenon took place because Korean fisheries had the antinomic characteristics that financial restriction was excessive owing to the industrial speciality of fisheries, on the other hand there was a large financial demand in fisheries in the character of industry.

• 만화애니메이션 연구
• /
• 통권10호
• /
• pp.33-53
• /
• 2006

본 논문에서는 한국 근대사회 대중문화의 신총아(新寵兒)로 자리매김 된 만화의 특징을 분석하고 그 사회적 의미를 밝혀 한국만화의 역사적 위상 정립을 위한 연구를 목적으로 하였다. 만화가 학문으로서 연구 영역을 확대하고, 한국 사회 속에서 독특한 대중문화장르로 자리매김하기 위해서는 태동기부터 한국만화가 갖는 역사적 위상을 고찰하고 정립해 나가는 것이 필요하다. 만화는 시각문화로 문맹률 높던 근대한국사회에서 커뮤니케이션 매체의 목적을 훌륭하게 실현한 장르였다. 이 시기 근대만화의 등장은 격변기(激變期) 대중을 계도(棨導)하며 주권회복운동을 펼쳐 나갔던 개화파 지식인들에게 중요한 선전 ${\cdot}$ 교육의 도구였으며, 역으로 친일의 수단이 되기도 하였다. 또 영리를 목적으로 매체를 운영하던 신문사(출판사)들에게는 중요한 독자 확보의 수단이었다. 이러한 측면에서 본 논문은 1900년대 초반부터 1945년 일제강점기에서 해방을 맞는 시기까지를 한국만화의 태동기로 보고 그 특징을 밝혀 보고자 한 것이다.

• 한국주거학회논문집
• /
• 제22권3호
• /
• pp.123-134
• /
• 2011

'Sohawjang' is the first apartment house built in Busan the modern period, 1944. 'Sohawjang' needs to be apprised its value as an very important object of study with architectural and dwelling historic meaning because multi-family houses built in Japanese Rule Era that now exist in Korea are very rare. Thus, this study attempted to leave records to archive by conducting face to face interviews and surveying on 'Sohawjang' which is seriously in danger of extinction and its original form damage as the first step. Especially, around Korea's Liberation, this study tried to extract transformation characteristics of residential space and cultural differences appeared on differences of occupants having different nationality. Through these results, this study attempted to examine the era of apartment house and transformation characteristics and values of modern dwelling historic dimension according to changes of users appeared in Busan modern period. Through this study, it offers basic data about introduction and transition processes of an apartment house in Korea. It has an meaning of suggestion reference data for original form preservations or regenerations.

• 한국주거학회논문집
• /
• 제19권6호
• /
• pp.137-144
• /
• 2008

Public housing problem became a major issue in each European country during the period of the reconstruction. This study focuses on the one of the major institutional policies in the public housing sectors in Europe during the second postwar period, specifically the INA (Istituto Nazionale delle Assicurazioni)-Casa in Italy from 1949 to 1963. Thanks to the financial Aid provided by 'Marshall Plan' of United States government, Italy initiated INA-Casa housing program elaborated and realized by minister of Labour, Amintore Fanfani. He was strongly influenced by catholic socialism and Weberian corporatism, and also had previously written theoretical studies on the subject during the Interwar years. The outcome of this policy had been devaluated for its Keynesian aspect as well as vernacular predominance in the architectural forms. On the contrary, this study focuses on themes such as continuity of politics before and after the Liberation, status of the architects and their will to social engagement, notion of quarter as 'self-sufficient community' and 'residential unit'. These factors will allow to comprehend the complex nature of the reality where different categories were involved to resolve the common housing problem.

• 한국시스템다이내믹스연구
• /
• 제10권4호
• /
• pp.53-72
• /
• 2009

More than 24.43 million people received a special pardon to mark the anniversary of Liberation Day on Aug. 15 and to commemorate other national event, during 15years(1995-2009), in this period six times of presidential pardon was implemented. The special pardon allows traffic law violator to drive again with their violation records wiped clean. But traffic records show that traffic accidents used to increase very fast in a short period by up to 3-15 percent after implementing the every massive pardons. This study explores the causal feedback relationship between presidential special pardon for traffic law violators and the occurrence of an traffic accidents using a system thinking approach and simulation modelling. Particularly, this study focused on the analysing significant negative impact of the traffic pardon on the occurrence of worrisome traffic accidents. The results of this study show that presidential special pardon have had impact on the traffic accidents as a increasing leverage of positive feedback loop and the obedience of traffic law as a decreasing leverage of negative feedback loop. Finally, this study conclude that the cyclical increasing pattern of traffic accident is resulting from the periodically conducted presidential pardons with political aims.

• 한국의류산업학회지
• /
• 제23권4호
• /
• pp.439-447
• /
• 2021

The purpose of this study is to examine the evolution of precious metal and gem stores, and to derive the characteristics of this period from the government, industry, and consumers. Correspondingly, the contents of daily newspaper articles during this period were analyzed using Naver's news library search engine. The historical development process is as follows. Before the Korean War, precious metal jewelers operated in Jongno, Namdaemun, and Chungmuro, dealing with gold, silver, and platinum. Large stores not only sold jewelry and watches, but also functioned as craftsmen and watch repairers. After the war, a shopping district for precious metals and jewelry was formed around Midopa Department Store. By 1963, the number of jewelry stores in Seoul increased to about 130 and to about 280 by 1966. The characteristics of the government, industry, and consumers are as follows. The government continued to implement a policy to regulate the precious metal and jewelry industry. Despite challenges, the industry exhibited the potential for foreign currency acquisition and growth through domestic amethyst. Consumers could access information regarding precious metal jewelry in daily newspapers. In the late 1960s, various types of jewelry were distributed in line with an increase in income levels.

• 한국농촌건축학회논문집
• /
• 제25권2호
• /
• pp.17-24
• /
• 2023

Seokgojeon(石鼓殿) is a protective pavilion that protects stone drums made in 1902 during the Korean Empire in connection with Emperor Gojong's Mangyuksun (51'st birthday) and the commemoration of the 40th anniversary of his reign. During the Japanese colonial period, Seokgojeon was dismantled and transformed into the bell pavilion of Bakmunsa Temple, which was a memorial temple for Ito Hirobumi in 1935. In November 1945, just after liberation, Bakmunsa Temple was burned down, and the Seokgojeon Hall, which was transformed into Jonggak(鐘閣), was relocated to the Changgyeongwon(昌慶苑). Outdoor Stage in 1966, and was dismantled in 1984 due to the Changgyeonggung(昌慶宮) Palace restoration project, and only the members are currently stored. Therefore, this paper intends to use it as a basic research data to examine the style of monumental buildings during the Korean Empire through literature surveys, absence surveys, and case studies of similar buildings during the same period.

• 한국세라믹학회지
• /
• 제22권2호
• /
• pp.33-38
• /
• 1985

The hydration of supersulphated slag cement which is the mixture of granuloated blast furnace slag anhydrite $C_4A_3$ type clinker and calcined dolomite was studied by X-ray diffraction differential thermal analysis scanning electron microscope observation and measurement of the rate of heat liberation. The main hydrates were ettrigite and C-S-H. This supersulphated slag cement enhanced rapid-hardening and increased in strength at early stage due to the much of ettrigite. Furthermore the hardened cement became stronger due to the C-S-H that was produced from the hydration of the $eta$-$C_2S$ in $C_4A_3$ type clinker and the hydration of the dissolved components from slag at later period.