• Title/Summary/Keyword: Lew

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Flavonoids from Kyllinga brevifolia var. leiolepsis (수오공의 Flavonoid 성분)

  • Lew, Jung-Hie;Kwak, Jong-Hwan;Zee, Ok-Pyo;Lee, Kang-Ro
    • Korean Journal of Pharmacognosy
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    • v.29 no.2
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    • pp.71-74
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    • 1998
  • Four flavonoids were isolated from the whole plant of Kyllinga brevifolia var. leiolepsis. Their structures were identified as quercetin, (-)-epiafzelechin, vitexin and orientin on the basis of spectral data. This is the first report of the identification of quercetin, (-)-epiafzelechin and orientin from Kyllinga genus.

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Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients

  • Lew, Wook;Nakamura, Koichiro;Tada, Yayoi;Kwahck, Ho;Chang, Soo Kyoung;Tamaki, Kunihiko
    • IMMUNE NETWORK
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    • v.2 no.4
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    • pp.223-226
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    • 2002
  • Background: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the serum levels of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-2 receptor, IL-10, IL-$1{\beta}$, IL-1 receptor antagonist and monocyte chemoattractant protein-1 (MCP-1) were reported to be higher in lepromatous leprosy. TNF-${\alpha}$ is also known to be higher in ENL, which is reduced after thalidomide treatment. However the serum type 2 chemokine levels in lepromatous leprosy patients have not been reported. Methods: The serum levels of the type 2 chemokines such as thymus and activation-regulated chemokine (TARC), macrophage-derived chemokine (MDC) and eotaxin together with IL-12 and IL-10 in the sera from leprosy patients were detected using an enzyme-linked solvent assay (ELISA) method. Results: The Serum TARC, MDC, eotaxin, IL-10 and IL-12 levels in lepromatous leprosy patients were not significantly different from the normal control levels. The serum levels were not significantly different between the paucibacillary group and multibacillary group. The serum TARC or MDC levels in the ENL patients were more reduced after a treatment containing thalidomide. Conclusion: The type 2 chemokines are not related to the severity of lepromatous leprosy. The larger reducing effect of the TARC or MDC levels in ENL patients by a treatment containing thalidomide suggests the potential role of these chemokines in the development of ENL and the therapeutic mechanism of thalidomide.

Studies on the Classification and Amylase Producing Activity of Fungi Isolated from Various Local Grains and Fermented Pastes (각종(各種) 곡류(穀類) 및 효소식품(酵素食品)에서 분리(分離)된 진균류(眞菌類)의 분류(分類) 및 Amylase 생성능(生成能)에 관(關)한 연구(硏究))

  • Koh, Choon-Myung;Lew, Joon
    • The Journal of the Korean Society for Microbiology
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    • v.5 no.1
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    • pp.19-26
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    • 1970
  • 1. Of the 35 various grains, 446 colonies of fungi were isolated. Among the 446 colonies, 423 were possible to identify into 17 genera. 2. Of the 10 bean-pastes, fungi were isolated 193 colonies. It can be identified 11 genera. 3. It will be noted that Aspergillus sp., Penicillium sp., Mucor sp., Cladosporium sp. were predominated genera. 4. A total of 155 colonies of Aspergillus sp. isolated from various grains were obtained from the samples. Asp. versicolor was the frequent species and 47 colonies isolated. 5. Penicillium where was isolated from various grains, obtained 115 colonies. Pen. camemberti was the most frequent species. 6. Penicillium palitans was most excellent amylase producing fungi and which was 1ml per 6.300 unit.

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Electron Microscopic Observations of the Effects of Thiocarbanilides(L-1) on Dermatophytes (표재성(表在性) 진균(眞菌)의 Thiocarbanilide(L-1) 처리효과에 대(對)한 전자현미경적(電子顯微鏡的) 관찰(觀察))

  • Koh, Choon-Myung;Kim, Tai-Won;Lew, Joon
    • The Journal of the Korean Society for Microbiology
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    • v.5 no.1
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    • pp.9-18
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    • 1970
  • The present study is of ultra-fine structures of Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis and Epidermophyton floccosum by means of electron microscopy and reveals the following. 1. In contrast to the bacteria, the normal fungus contains nuclear membrane, mitochondria, endoplasmic reticulun, distinct cell wall and cell membrane and secretory granules as observed in the higher plants and animals. 2. Thickening of the cell wall, inapparent cell wall, inapparent cell membrane with the appearance of electron thin area(ETA) and increase of inclusions were observed in the L-1 treated groups. 3. Thickening of cell wall and increase of ETA were more apparent in the Epidermophyton floccosum than the other groups. 4. Increase of electron thin area was thought to be associated with autolysis.

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An Experimental Study of Pneumatic Damping at the Air Chamber for OWC type Wave Energy Device (OWC형 파력발전 공기챔버의 공기감쇠력 실험연구)

  • CHOI Hark-Sun;LEW Jae-Moon;HONG Seok-Won;KIM Jin-Ha
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2004.05a
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    • pp.138-144
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    • 2004
  • Pneumatic damping through a orifice type duct for OWC type wave energy device is studied experimentally. Forced oscillation tests are made to measure chamber pressure and velocity of air flaw through orifice. Pneumatic damping coefficient are deducted from the experimental research, and discussion are made far the influence of frequency, heave amplitude, and orifice size. Finally two formula are proposed for the estimation of non-dimensional pneumatic damping coefficient by regression analysis. The proposed formula proves to be a reliable method far practical application.

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