• Title/Summary/Keyword: Lee Seong-Ah

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Attitudes toward Social Issues Related to Opioid Use among Palliative Care Physicians

  • In Cheol Hwang;Seong Hoon Shin;Youn Seon Choi;Myung Ah Lee;DaeKyun Kim;Kyung Hee Lee
    • Journal of Hospice and Palliative Care
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    • v.27 no.1
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    • pp.45-49
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    • 2024
  • Purpose: This study investigated palliative care physicians' attitudes regarding social issues related to opioid use. Methods: An email survey was sent to 674 physicians who were members of the Korean Society for Hospice and Palliative Care (KSHPC). Results: Data from 66 physicians were analyzed (response rate, 9.8%). About 70% of participants stated that their prescribing patterns were not influenced by social issues related to opioid use, and 90% of participants thought that additional regulations should be limited to non-cancer pain. Under the current circumstances, pain education for physicians is urgently needed, as well as increased awareness among the public. Half of the respondents identified the KSHPC as the primary organization responsible for providing pain education. Conclusion: Palliative care physicians' prescribing patterns were not influenced by social issues related to opioid use, and these issues also should not affect cancer pain control.

A Study on the Application of Agricultural Nonpoint Source Pollution(AGNPS) Model using GIS and RS (GIS와 RS를 이용한 비점원오염 모형의 적용에 관한 연구)

  • Kim, Seong-Joon;Lee, Yun-Ah;Lee, Nam-Ho;Yoon, Kwang-Sik;Hong, Seong-Gu
    • Journal of the Korean Association of Geographic Information Studies
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    • v.3 no.4
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    • pp.63-72
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    • 2000
  • The objective of this study was to identify the applicability of AGNPS(Agricultural Nonpoint Source Pollution) model using RS data; Landsat TM merged by KOMPSAT EOC and GIS data. AGNPS model which is well-known distributed nonpoint source pollution model was used as the assessment tool. This model has the capability to adjust the level of pollutant load from farmstead and the fertilization level of upland field. A small agricultural watershed($4.12km^2$) which has 20 livestock farmhouses located in Gosan-myun, Ansung-gun was selected. AGNPS data were prepared by using Arc/Info, GRASS, ER-Mapper and Idrisi. Four storm events in 1999 were used for runoff calibration, and 2 storm events which were measured in hourly-base at 4 locations along the stream were used for water quality(TN, TP) calibration.

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Factors Associated with the Stability of Two-part Mini-implants for Intermaxillary Fixation

  • Kim, Seong-Hun;Seo, Woon-Kyung;Lee, Won;Kim, In-Soo;Chung, Kyu-Rhim;Kook, Yoon-Ah
    • Journal of Korean Dental Science
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    • v.2 no.2
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    • pp.24-30
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    • 2009
  • Two component orthodontic C-implants have been introduced as intermaxillary fixation (IMF) screws in cases of periodontal problems with bone loss, severely damaged teeth, or short roots. This retrospective research sought to investigate the complications and risk factors associated with the failure of two-part C-implants for IMF cases and to show the possible indications compared to one-component mini-implants. The study sample consisted of 46 randomly selected patients who had a total of 203 implants. Pearson chi-square tests of independence were used to test for associations among categorical variables. At least 19 of the total 203 implants failed (9.3%). There was no significant difference in implant failure due to gender, oral hygiene, and placement, although a significant difference due to soft tissue characteristics and root contact was observed. The two-component design of the mini-implant is reliable for difficult IMF cases. Note, however, that the factors influencing implant failure were found to be age, root damage, and condition of soft tissues.

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Toxicoproteomic Analysis of Differentially Expressed Proteins in Rat Liver by DEHP

  • Son, Bu-Soon;Seong, Ah-Reum;Park, Seul-Ki;Kim, Wan-Jong;Ryu, Jae-Chun;Lee, Mi-Young
    • Molecular & Cellular Toxicology
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    • v.3 no.4
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    • pp.299-305
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    • 2007
  • The endocrine disrupting chemical, di (2-ethylhexyl) phthalate (DEHP) is a plasticizer used in polyvinyl chloride products ubiquitous in our daily lives. DEHP has potentially adverse effects on the liver, kidney, lung, heart, reproductive organs and endocrine systems. Many toxicological data on the DEHP toxicity have been stated, but complete protein profiles have not yet been reported. In this study, DEHP-induced oxidative DNA damage in rat lymphocyte was evaluated by Comet assay (single-cell gel electrophoresis) for the first time. Moreover, DEHP-induced protein profile alterations were examined in rat liver by using toxicoproteomic tools. 34 protein spots in the liver were identified to be significantly deregulated by DEHP on the 2-dimensional gel. Among them, 20 spots were up-regulated and 14 spots down-regulated by DEHP.

Three Dimensional Computational Study on Performance and Transport Characteristics of PEMFC by Flow Channel Patterns (유로형상 변화에 따른 고분자 전해질 연료전지의 성능 및 전달특성에 대한 3차원 수치해석적 연구)

  • Lee, Pil-Hyong;Cho, Son-Ah;Choi, Seong-Hun;Hwang, Sang-Soon
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.11a
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    • pp.407-410
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    • 2006
  • Selection of flow channel in the separation plate of PEMFC is very important parameter to improve its performance and reduce parasite loss. Flow patterns in the channel have great influence on the transport of hydrogen and all and water generated from electrochemical reaction in diffusion layer In this study, fluid flow in flow channel with parallel and interdigitated patterns are simulated three dimensionally on full flow domain including anode and cathode electrode together. The numerical results show that the fuel cell with interdigitated flow channel represents better performance than that with parallel flow channel due to its strong convective transport across the gas diffusion layer. But the pressure drop in parallel flow channel is much more than that in nterdigitated flow channel. The effect of temperature and stoichiometric number on performance can be calculated and analyzed as well.

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Anti-inflammatory Activities of Ethylacetate Extract of Rehmannia glutinosa in LPS-induced RAW 264.7 Cells

  • Jin, Chang-Hyun;Lee, Young-Man;Kang, Min-Ah;Park, Yong-Dae;Choi, Dae-Seong;Byun, Myung-Woo;Jeong, Il-Yun
    • Food Science and Biotechnology
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    • v.18 no.4
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    • pp.923-927
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    • 2009
  • This study is to investigate the anti-inflammatory effects of the ethylacetate extract of Rehmannia glutinosa (RGEAE). The anti-inflammatory activities using nitric oxide (NO), cytokine, and chemokine production in lipopolysaccharide (LPS)-induced RAW 264.7 cells were checked. Results indicated that RGEAE suppressed the NO, interleukin-6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1) production in a dose-dependent manner. Inhibition of NO formation was due to a decrease in inducible NOS (iNOS) expression. It was also found that the anti-inflammatory activities of RGEAE resulted from its inhibitory role on the nuclear factor $(NF)-{\kappa}B$ activation and reactive oxygen species (ROS) production. Therefore, it is suggested that RGEAE has potential as a therapeutic material to attenuate the inflammatory disease such as rheumatoid arthritis.

Screening and Characterization of an Esterase from a Metagenomic Library

  • KIM JEONG-NYEO;SEO MYUNG-JI;CHO EUN-AH;LEE SANG-JAE;KIM SEONG-BO;CHEIGH CHAN-ICK;PYUN YU-RYANG
    • Journal of Microbiology and Biotechnology
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    • v.15 no.5
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    • pp.1067-1072
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    • 2005
  • A metagenomic library was constructed using a fosmid vector, and total genomic DNA was extracted directly from soil at Cisolok (hot spring area, Indonesia). This library was composed of 10,214 clones and screened for lipolytic enzyme on tributyrin agar plates. An esterase gene (estMa) was subcloned and sequenced from a positive lipolytic active clone. Esterase EstMa was encoded by a 954-bp open reading frame and showed low ($11-33\%$) amino acid similarity to known esterases. The amino acid sequence analysis demonstrated that the enzyme is a new member of lipolytic enzyme family VI. The estMa gene encodes a preprotein of 317 amino acids with a predicted molecular mass of 34,799 Da. The purified enzyme exhibited optimal activity at $50^{\circ}C$ and pH 6.5. The $K_m,\;and\;V_{max}$ values of EstMa for the hydrolysis of p-nitrophenyl valerate were $45.3\;{\mu}M$ and 4.45 U/mg, respectively.

Preparation of Cathode Materials for Lithium Rechargeable Batteries using Transition Metals Recycled from Li(Ni1-x-yCoxMny)O2 Secondary Battery Scraps (Li(Ni1-x-yCoxMny)O2계 이차전지 공정 스크랩으로부터 회수한 전이금속을 활용한 리튬이차전지 양극재 제조)

  • Lee, Jae-Won;Kim, Dae Weon;Jang, Seong Tae
    • Journal of Powder Materials
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    • v.21 no.2
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    • pp.131-136
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    • 2014
  • Cathode materials and their precursors are prepared with transition metal solutions recycled from the the waste lithium-ion batteries containing NCM (nickel-cobalt-manganese) cathodes by a $H_2$ and C-reduction process. The recycled transition metal sulfate solutions are used in a co-precipitation process in a CSTR reactor to obtain the transition metal hydroxide. The NCM cathode materials (Ni:Mn:Co=5:3:2) are prepared from the transition metal hydroxide by calcining with lithium carbonate. X-ray diffraction and scanning electron microscopy analyses show that the cathode material has a layered structure and particle size of about 10 ${\mu}m$. The cathode materials also exhibited a capacity of about 160 mAh/g with a retention rate of 93~96% after 100 cycles.

Corpus Analyzer for Linguists (언어학자를 위한 말뭉치 분석기)

  • Jeong, Seok-Pal;Lim, Seong-Jyeon;Jeon, Jin-Hyeong;Lee, Hyun Ah
    • Annual Conference on Human and Language Technology
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    • 2012.10a
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    • pp.95-98
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    • 2012
  • 말뭉치는 언어를 연구하기 위한 중요한 재료이다. 본 논문에서는 말뭉치에서 나타나는 언어 현상을 보다 효율적으로 분석하기 위한 언어학자를 위한 말뭉치 분석기를 제안하고 그 구현 방법을 설명한다. 제안하는 말뭉치 분석기는 기본적인 통계 정보와 함께, 형태소 분석된 파일을 대상으로 위치 색인을 포함하는 역파일 색인을 구성하여 빠른 형태소 검색과 다앙한 수준의 연어 검색을 제공한다. 분석기는 세종말뭉치를 기본 말뭉치로 하며, 다앙한 말뭉치에 대한 통계자료와 검색 기능을 제공하기 위해 사용자 말뭉치 파일에 대한 처리도 지원한다. 시스템은 사용자가 업로드한 말뭉치 파일에 대하여 자동 형태소 분석을 제공하며 형태소 분석 결과 수정을 가능하게 하여 다앙한 말뭉치에서 언어학자들의 우리말 연구를 지원한다.

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Comparison of Four-view Abdominal Radiographic Studies on Duodenal Gas Pattern in Dog

  • Noh, Seul-ah;Yoon, Young-min;Hwang, Tae-sung;Shin, Chang-ho;Lim, Jong-su;Yeon, Seong-chan;Lee, Hee-chun
    • Journal of Veterinary Clinics
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    • v.34 no.5
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    • pp.325-329
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    • 2017
  • In this retrospective study the effect of positioning on the radiographic appearance of duodenum and the radiographic differences of duodenal gas pattern between dogs without pancreatitis and dogs with pancreatitis were investigated. Ventrodorsal, dorsoventral as well as both lateral abdominal radiographs of 255 dogs were evaluated. Gas distribution in the duodenum, gastroduodenal angle, accuracy of the positioning was examined. The duodenum was more visible in a left lateral view and a dorsoventral view. The positioning of dorsoventral view was the most inaccurate. Based on this study, there were not significant differences in duodenal gas pattern between dogs without pancreatitis and dogs with pancreatitis.