• The Journal of Korean Medicine
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• v.18 no.1
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• pp.5-24
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• 1997

Clinical observation was made on 226 cases of CVA that were confirmed through brain CT, MRI scan and clinical observation. They were hospitalized in the oriental medical hospital of Kyung-Won University from January to December in 1995. 1. The CVA cases were classified into the following kinds: cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage(SAH), transient ischemic attack, and the greatest in number among them were the cases of cerebral infarction. 2. The frequency of strokes was much the same between male and female cases and most cases were over 50 of age. 3. In the case of cerebral infarction the place of the most frequent occurrences was in the MCA territory, and as for cerebral hemorrhage, in the basal ganglia area. 4. The most ordinary preceding disease was hypertension. The next was diabetes mellitus. 5. Generally it is thought that CVA occurs frequently in winter. But on the contrary this study of observation confirmed that it occurs mostly in spring and summer. 6. The predisposing factors of cerebral infarction were usually initiated during the time of resting and sleeping and those of cerebral hemorrhage chiefly during the time of exercising. 7. As concerns the course of hospitalization, most patients passed through vestern medical hospitals or oriental medical hospitals. 8. For the patients the condition of whose consciousness was bad at the time of admission. the prognosis in most cases was bad. 9. The common symptoms were motor disability and verbal disturbance. 10. With regard to cerebral infarction, the average time to start physical theraphy was 6.4 days and with cerebral hemorrhage 9.7 days after stroke. 11. The duration of hospitalization was in most cases more than one month. 12. The main complication was urinary tract infection. 13. At the time of admission to hospital, the blood pressure in most cases was high, but it well controlled at the time of discharge. 14. Most cases were given simultaneous treatment in both ways of western and oriental medicine.

• The Journal of Korean Academy of Prosthodontics
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• v.47 no.3
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• pp.301-311
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• 2009

Statement of problem: Flapless implant surgery using a soft tissue punch device requires a circumferential excision of the mucosa at the implant site. To date, Although there have been several reports on clinical outcomes of flapless implant surgeries, there are no published reports that address the appropriate size of the soft tissue punch for peri-implant tissue healing. Purpose: In an attempt to help produce guidelines for the use of soft tissue punches, this animal study was undertaken to examine the effect of soft tissue punch size on the healing of peri-implant tissue in a canine mandible model. Material and methods: Bilateral, edentulated, flat alveolar ridges were created in the mandibles of six mongrel dogs. After a three month healing period, three fixtures (diameter, 4.0 mm) were placed on each side of the mandible using 3 mm, 4 mm, or 5 mm soft tissue punches. During subsequent healing periods, the peri-implant mucosa was evaluated using clinical, radiological, and histometric parameters, which included Gingival Index, bleeding on probing, probing pocket depth, marginal bone loss, and vertical dimension measurements of the peri-implant tissues. Results: The results showed significant differences (P <0.05) between the 3 mm, 4 mm and 5 mm tissue punch groups for the length of the junctional epithelium, probing depth, and marginal bone loss during healing periods after implant placement. When the mucosa was punched with a 3 mm tissue punch, the length of the junctional epithelium was shorter, the probing depth was shallower, and less crestal bone loss occurred than when using a tissue punch with a diameter $\geq$ 4 mm. Conclusion: Within the limit of this study, the size of the soft tissue punch plays an important role in achieving optimal healing. Our findings support the use of tissue punch that 1 mm smaller than implant itself to obtain better peri-implant tissue healing around flapless implants.

• Journal of dental hygiene science
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• v.17 no.6
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• pp.495-500
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• 2017

Hippophae rhamnoides L. (sea buckthorn) is a shrub wood that belongs to the bamboo tree family, and is rich in vitamin C, D, and E; it is referred to as a vitamin tree. It is mainly grown in the high mountains of Europe and Central Asia, and has been widely used in China and Russia as natural medicine. Recent studies have shown that it is effective in the treatment of cancer, liver diseases, cardiovascular diseases, and gastrointestinal diseases. However, results of studies on its effect on the regulation of pain are insufficient. In this study, we investigated the effect of sea buckthorn on the development and control of pain in two facial areas. The experimental animals included 7- to 8-week-old Sprague-Dawley rats (240~260 g). Formalin (5%), which is known as an inflammation inducer, was injected into the vibrissa pad or temporomandibular joints to induce orofacial acute pain. Rubbing or scraping of the region injected with formalin was regarded as a pain index, and the behavioral response was observed for 45 minutes after the injection. Sea buckthorn extract diluted to 150, 300 mg/kg (in 1 ml of distilled water) was orally administered 30 minutes prior to the acute pain. The facial pain behavior was effectively reduced in the 300 mg/kg group when compared to the control group (vehicle). Likewise, in an experiment in which formalin was injected into the temporomandibular joints, effective pain alleviation was confirmed at the same drug concentration. These results suggest that sea buckthorn extract may be useful in the development of therapeutic agents for acute inflammatory pain in the orofacial area and for controlling temporomandibular joint pain.

• Korean Journal of Environment and Ecology
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• v.30 no.2
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• pp.243-252
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• 2016

Comparison of Organic carbon in the Quercus mongolica and Pinus densiflora forest at Mt. Gumgang were investigated. Carbon in above and below ground standing biomass, litter layer, and soil organic carbon were measured from September 2013 through August 2014. For the estimation of carbon cycling, soil respiration was measured. The amount of carbon allocated to above and below ground biomass in Q. mongolica and P. densiflora forest was 115.07/34.36, $28.77/8.59ton\;C\;ha^{-1}$, respectively. Amount of organic carbon in annual litterfall in Q. mongolica and P. densiflora forest was 4.89, $6.02ton\;C\;ha^{-1}$, respectively. Amount of organic carbon within 50cm soil depth was 132.78, $59.72ton\;C\;ha^{-1}$ $50cm-depth^{-1}$, respectively. Total amount of organic carbon in Q. mongolica and P. densiflora forest estimated to 281.52, $108.69ton\;C\;ha^{-1}$, respectively. Amount of organic carbon returned to the forest via litterfall in Q. mongolica and P. densiflora forest was 2.83, $2.20ton\;C\;ha^{-1}$, respectively. The amount of organic carbon absorbed from the atmosphere of this Q. mongolica and P. densiflora forest was 3.90, $0.81ton\;C\;ha^{-1}yr^{-1}$ respectively. Absorption of organic carbon in Q. mongolica forest was remarkably higher than P. densiflora forest.

• Korean Journal of Acupuncture
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• v.31 no.1
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• pp.5-13
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• 2014

Objectives : This study aims to evaluate the effectiveness and safety of acupuncture and explore the appropriate number of treatment for postmenopausal women diagnosed with prehypertension and stage 1 hypertension. Methods : A 4-arm randomized open label pilot trial will be performed at 2 centers. Sixty participants will be divided into 2 treatment groups and 2 control groups. Treatment groups will receive acupuncture at 8 points(bilateral GB20, LI11, ST36, SP6) for 4 weeks(treatment group A, 10 total sessions) or 8 weeks(treatment group B, 20 total sessions), while maintaining usual care. Control groups will not receive acupuncture but will be under usual care for 16 weeks(control group C) or 20 weeks(control group D). Each patient's living habits will be corrected and drugs that may affect blood pressure(BP) will be prohibited. Treatment group A and control group C will be evaluated at 4, 8, 12, and 16 weeks after randomization, while treatment group B and control group D will be evaluated at 4, 8, 12, 16, and 20 weeks after randomization. The major outcome variable is the magnitude of change in diastolic BP levels at 4 weeks after randomization; auxiliary outcome variables are (1) diastolic BP change at 8, 16, and 20 weeks, (2) systolic BP change, (3) BP control rate, (4) lipid profiles, and (5) high-sensitivity C-reactive protein. Patient safety will be assessed at every visit. Results and Conclusions : The study findings may help develop evidence for the effectiveness and safety of acupuncture for BP control.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.3
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• pp.308-315
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• 2006

Since sewage characteristics are the most important factors that can affect the biological reactions in wastewater treatment plants, a detailed understanding on the characteristics and on-line measurement techniques of the influent sewage would play an important role in determining the appropriate control strategies. In this study, samples were taken at two hour intervals during 51 days from $1^{st}$ October to $21^{st}$ November 2005 from the influent gate of sewage treatment plant. Then the characteristics of sewage were investigated. It was found that the daily values of flow rate and concentrations of sewage components showed a defined profile. The highest and lowest peak values were observed during $11:00{\sim}13:00$ hours and $05:00{\sim}07:00$ hours, respectively. Also, it was shown that the concentrations of sewage components were strongly correlated with the absorbance measured at 300 nm of UV. Therefore, the objective of the paper is to develop on-line estimation technique of the concentration of each component in the sewage using accumulated profiles of sewage, absorbance, and flow rate which can be measured in real time. As a first step, regression analysis was performed using the absorbance and component concentration data. Then a neural network trained with the input of influent flow rate, absorbance, and inflow duration was used. Both methods showed remarkable accuracy in predicting the resulting concentrations of the individual components of the sewage. In case of using the neural network, the predicted value md of the measurement were 19.3 and 14.4 for TSS, 26.7 and 25.1 for TCOD, 5.4 and 4.1 for TN, and for TP, 0.45 to 0.39, respectively.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.7
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• pp.975-982
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• 2015

Piceatannol (trans-3,4,3',5'-trihydroxystilbene), a natural stilbene, is an analogue of resveratrol. In the present study, possible mechanisms by which piceatannol exerts its pro-apoptotic action in cultured human oral cancer YD-15 cells were investigated. To investigate whether or not piceatannol has effects on cancer cell viability, human oral YD-15 cells were treated with piceatannol (0, 50, and $100{\mu}M$). Piceatannol treatment ($100{\mu}M$) showed the strongest inhibition of cell proliferation and reduced cell viability in a dose-dependent manner. Chromatin condensation detected by DAPI staining significantly increased in a concentration-dependent manner, indicating apoptosis. Piceatannol treatment activated initiator Bax (pro-apoptotic) and cPARP in a concentration-dependent manner. Further, piceatannol induced down-regulation of Bcl-2 (anti-apoptotic). We also evaluated the activity of piceatannol against oral cavity cancer tumors in mice. Piceatannol-treated nude mice bearing YD-15 xenograft tumors exhibited significantly reduced tumor volume and weight due to the potent effect of piceatannol on tumor cell apoptosis, as determined by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay. Immunohistochemistry staining showed elevated expression of cleaved-caspase-3 as well as reduced expression of Ki-67 in the piceatannol-treated group. Therefore, piceatannol can be developed as a cancer preventive medicine due to its growth inhibitory effects and induction of apoptosis in human oral cancer cells.

• Korean journal of applied entomology
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• v.55 no.4
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• pp.329-336
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• 2016

Occurrence of oriental corn borer, Ostrinia furnacalis, and yield in a paddy-upland rotation field for 8 maize (Eolrukchal 1, Heugjeom 2, Miheukchal, Ilmichal, Heukjinjuchal, Chalok 4, Mibaek 2, Daehakchal) and 7 sorghum (Hwanggeumchal, Anzunbaengisusu, Moktaksusu, Sodamchal, DS-202, Nampungchal, Donganme) varieties has been surveyed. In a monitoring study using a pheromone trap carried out from 15 May to 10 September, the density of O. furnacalis adults increased rapidly from about 2 weeks after maize planting and reached the highest density at mid June. After that, their density was fluctuated a little at earlier September. The number of the damaged maize and invasive pores on the stem of 2 maizes and sorghum varieties was examined. The mean number of the damaged maize per 20 plants was 19 and 18 plants, and the number of invasive pores was 1.8 and 1.4 per maize stem in Daehakchal and Mibaek 2, respectively. In a survey carried out at harvest period using 8 maize varieties, the damaged ratio was 94%, 92%, 71%, 64%, 54%, 52%, and 45% in Daehakchal, Mibaek 2, Ilmichal, Eolrukchal 1, Chalok 4, Miheukchal, and Heugjeom 2, respectively. The number of invasive pore per Ilmichal stem was 1.4 and that of the others was less than 1.0 per stem. In addition, the damaged ratio of maize ears was 50% in Ilmichal, 40% in Heukjinjuchal, 37% in Daehakchal, etc. The damage pattern of 2 sorghum varieties, Nampungchal and Donganme, by O. furnacalis larvae was steeply increased from planting to 2 months and the trend was continued up to earlier August. At this time, the mean number of damaged sorghum was 13 and 9.2 plants for Nampungchal and Donganme, and the number of invasive stem pores was 1.06 and 0.46, respectively. In another survey carried out at harvest period for 7 sorghum varieties, their damaged ratio was 95% in DS-202, 76% in Moktaksusu, 75% in Sodamchal, 67% in Nampungchal, 57% in Anzunbaengisusu, 46% in Donganme, and 34% in Hwanggeumchal. The damage of sorghum varieties was much higher and severer than that of maizes by O. furnacalis larvae. The number of invasive pores on a sorghum stem was 1.7 in DS-202, 1.4 in Moktaksusu, 1.3 in Sodamchal, 1.1 in Nampungchal, 1.0 in Anzunbaengisusu, 0.5 in Donganme, and 0.4 in Hwanggeumchal. Meanwhile, there was no distinct connection between damaging results and yields of maizes and sorghums by O. furnacalis larvae in a paddy-upland rotation field. These results from this study can be applicable for the establishment of a management strategy to control Oriental corn borer in paddy-upland rotation fields for maize and sorghum.

• Korean Journal of Environment and Ecology
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• v.27 no.5
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• pp.561-570
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• 2013

Organic carbon distribution and carbon budget of a Pinus densiflora forest in the Songgye valley of Mt. Worak National Park were investigated. Carbon in above and below ground standing biomass, litter layer, and soil organic carbon were measured from May 2011 through April 2012. For the estimation of carbon budget, soil respiration was measured. The amount of carbon allocated to above and below ground biomass was 52.25 and 14.52 ton C $ha^{-1}$. Amount of organic carbon in annual litterfall was 4.71 ton C $ha^{-1}$. Amount of organic carbon within 50cm soil depth was 58.56 ton C $ha^{-1}$ 50cm-$depth^{-1}$. Total amount of organic carbon in this Pinus densiflora forest was estimated to 130.04 ton C $ha^{-1}$. Amount of organic carbon in tree layer, shrub and herb layer was 4.12, 0.10 and 0.04 ton C $ha^{-1}yr^{-1}$ and total amount of organic carbon was 4.26 ton C $ha^{-1}yr^{-1}$. Amount of organic carbon returned to the forest via litterfall was 1.62 ton C $ha^{-1}yr^{-1}$. The amount of carbon evolved through soil respiration was 6.25 ton C $ha^{-1}yr^{-1}$. The amount of carbon evolved through microbial respiration and root respiration was 3.19 and 3.06 ton C $ha^{-1}yr^{-1}$. The amount of organic carbon absorbed from the atmosphere of this Pinus densiflora forest was 1.07 ton C $ha^{-1}yr^{-1}$ when it was estimated from the difference between Net Primary Production and microbial respiration.

• Journal of the Korean Society of Food Science and Nutrition
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• v.40 no.4
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• pp.557-564
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• 2011

This study was performed to investigate changes in ${\gamma}$-aminobutyric acid (GABA) and isoflavones in traditional Korean Doenjang according to ripening periods. The traditional Korean Doenjang used in this research was produced at Seowon Agricultural Cooperative in Gangwon-do Province, and samples fermented for periods of 1, 3, 5, 7, and 10 years were used. Doenjang that was not fermented after production was used as a control group. The analysis results of general constituents indicated a decreasing tendency for moisture after a momentary increase until three years of fermentation. The pH and Hunter color values of the Doenjang samples decreased overtime. In the case of amino acids, generally there were no notable differences during fermentation, but glutamic acid, the precursor of GABA, significantly decreased with fermentation. GABA content for the control group was $24.9{\pm}0.8\;mg$/kg, while the traditional Korean Doenjang fermented for 1 year contained $43.8{\pm}0.2\;mg$/kg and after 3 years it increased to $120.6{\pm}3.9\;mg$/kg. Furthermore, samples fermented for 5 and 7 years contained $569.5{\pm}3.9\;mg$/kg and $930.7{\pm}7.1\;mg$/kg, respectively, and a 10 year old specimen had 77 times more GABA than the control group, with $1,938.7{\pm}4.8\;mg$/kg. This confirmed that GABA content increased with fermentation time. There were no significant differences in the isoflavone glycosides daidzin, genistin, and glycitin, but genistein and daidzein, which are aglycones, increased along with fermentation period by the actions of enzymes and microorganisms during fermentation.