• Nutrition Research and Practice
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• 제14권4호
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• pp.412-422
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• 2020

BACKGROUND/OBJECTIVES: This study investigates correlations between circulating microRNAs (miRNAs) and obesity-related parameters among young women (aged 20-30 years old) in Korea. SUBJECTS/METHODS: We analyzed TaqMan low density arrays (TLDAs) of circulating miRNAs in 9 lean (body mass index [BMI] < 25 kg/㎡) and 15 obese (BMI > 25 kg/㎡) women. We also performed gene ontology (GO) analyses of the biological functions of predicted miRNA target genes, and clustered the results using the database for annotation, visualization and integrated discovery. RESULTS: The TLDA cards contain 754 human miRNAs; of these, the levels of 8 circulating miRNAs significantly declined (> 2-fold) in obese subjects compared with those in lean subjects, including miR-1227, miR-144-5p, miR-192, miR-320, miR-320b, miR-484, miR-324-3p, and miR-378. Among them, miR-484 and miR-378 displayed the most significant inverse correlations with BMI (miR-484, r = -0.5484, P = 0.0056; miR-378, r = -0.5538, P = 0.0050) and visceral fat content (miR-484, r = -0.6141, P = 0.0014; miR-378, r = -0.6090, P = 0.0017). GO analysis indicated that genes targeted by miR-484 and miR-378 had major roles in carbohydrate and lipid metabolism. CONCLUSION: Our result showed the differentially expressed circulating miRNAs in obese subjects compared to lean subjects. Although the mechanistic study to reveal the causal role of miRNAs remains, these miRNAs may be novel biomarkers for obesity.

• 한국지구과학회지
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• 제31권5호
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• pp.521-530
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• 2010

This study aimed to explore how to characterize the earth science inquiry in schools in terms of science teaching interaction and constructivist teaching practice. The constructivist teaching practices were analyzed with Reformed Teaching Observation Protocol (RTOP) in three aspects including (1) student oriented class implementation, (2) subject knowledge and representation, and (3) classroom communication. Fourteen earth science classes were observed and scored with RTOP. The class was evaluated to be transitional stage in terms of constructivist teaching, e.g., moving toward student-centered teaching practice. Especially, Korean teachers tend to lean their classes more on propositional knowledge than procedural knowledge. To interpret science teaching interactions, an earth science teacher with a RTOP top rank was selected. Her class was then videotaped for detailed analysis. I adopted the analytical framework of communicative approaches and discourse patterns among the five aspects of interactions presented by Mortimer and Scott (2003). It was found that this earth science teacher used more authoritative patterns than the dialogic. In addition, she used IRE discourse pattern more frequently. Interestingly, teachers interacted with their students more frequently in the form of repeated (or IRE chain pattern), that is IRFRF (teacher initiation-student response-teacher feedback-student response-teacher feedback) in the context of dialogic communicative approaches, while simple IRE occurred in an authoritative approach. In earth science classrooms, typical interaction may well be constructed in the form of IRFRF chains to allow students free conjectures and abduction.

• 한국학교보건학회지
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• 제16권1호
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• pp.149-160
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• 2003

The purpose of this study was to analyze the effects after having the obesity education with obese elementary school children. The subjects were made up of 31 obese children out of U elementary school in B town as experimental group, and also were selected 34 children out of S elementary school under the same circumstance as control group. They ranged from the third to sixth grades with over 30% body fat ratio. The proceeding of obesity education consisted of three stage; stage for preparation, stage for practice, and stage for finish. The stages mentioned above were put into practice in turn for eleven weeks beginning on Oct. 8, 2001 through Dec. 22, 2001, while two stages only, stage for preparation and finish, were put into practice on the control group. The contents of the education for eleven weeks obesity regulation contained counseling and taking regular exercises once a week by professional gym teacher. In order to evaluate the effects of the education, physical characteristics, body composition, physical fitness, knowledge of obesity, dietry habit and attitude were measured. The obtained data were analyzed using SPSS program, the effects of pre and post obesity education in experimintal group were measured by paired-t test. The conclusions of this study were as follows : 1. Body fat ratio was significantly reduced after obesity education in experimintal group(p=.003). 2. The height with experimental group got taller remarkably(p=.000), but weight showed no signeficance after obesity education(p=.258). 3. Triceps and subscapular skinfold thickness showed remarkable decrese after obesity education(p=.000), percentage body fat and body fat amount got down remarkably after obesity education(p=.000). Percentage lean body mass and lean body mass amount got down remarkably after obesity education(p=.000). 4. Body flexibility, agility and muscle endurance graded up remarkably after obesity education(p=.009, p=.000, p=.000). 5. The grade in obesity knowledge got up remarkably after obesity education(p.000), but dietry habits and its life showed no significance in figures after obesity education(p=.335, p=.112). Through the results shown above, the obesity education caused body fat ratio, physique, body composition to grade up and physical fitness elevated, while dietry habits and its life showed no significance.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 춘계학술대회
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• pp.78-81
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• 2015

소프트웨어 개발 환경의 급격한 변화와 지속적인 요구사항 변경으로 인해 발생하는 전통적 개발 방법론의 문제점을 해결하기 위한 애자일 개발방법론은 관심의 대상이 되었다. 비교적 짧은 주기를 가지고 요구사항 분석, 설계, 코딩, 테스트 과정을 끊임없이 반복하며 점차 소프트웨어의 규모를 늘려가는 애자일 개발방법은 오픈소스 소프트웨어의 개발방식(OSSDP)과 매우 유사하다고 볼 수 있다. 지금까지 애자일 방법론은 Scrum, XP, Lean, Crystal 방식 등 여러 가지 방법으로 시도 및 제안되고 있으며, 점차 다양한 프로젝트에서도 성공적으로 수행할 수 있도록 개선되고 있다. 이러한 애자일 개발방식의 특징을 OSSDP에 적용함으로써 더 많은 오픈소스 프로젝트가 성공할 수 있도록 하는 프로세스를 연구하는 것은 의미가 있다. 애자일 성명서에서 추구하는 4가지 가치인 소통, 단순성, 피드백, 용기를 반영한 관행(practice)을 OSSDP에 채택하여 추가할 경우, 사용자 만족도를 높이고 결과적으로 오픈소스 프로젝트 성숙도를 높이는데 기여할 것으로 기대한다.

• Structural Engineering and Mechanics
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• 제11권1호
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• pp.1-16
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• 2001

This paper discusses the elastic stability of unbraced frames under non-proportional loading based on the concept of storey-based buckling. Unlike the case of proportional loading, in which the load pattern is predefined, load patterns for non-proportional loading are unknown, and there may be various load patterns that will correspond to different critical buckling loads of the frame. The problem of determining elastic critical loads of unbraced frames under non-proportional loading is expressed as the minimization and maximization problem with subject to stability constraints and is solved by a linear programming method. The minimum and maximum loads represent the lower and upper bounds of critical loads for unbraced frames and provide realistic estimation of stability capacities of the frame under extreme load cases. The proposed approach of evaluating the stability of unbraced frames under non-proportional loading has taken into account the variability of magnitudes and patterns of loads, therefore, it is recommended for the design practice.

• 비만대사연구학술지
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• 제1권2호
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• pp.59-65
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• 2022

Obesity is a serious health concern, which has been linked to an increased risk for cardiovascular diseases and some cancers. The traditional obesity control program is expensive. Moreover, it is difficult to maintain a healthy body weight as well as reduce body fat. The long-term use of effective and tolerable medication is carefully recommended to control body weight. In addition to obesity control medications, health functional foods, related to body weight control, have become popular in the commercial market. Known mechanisms include lipolysis, appetite control, inflammation reduction, and lean body mass maintenance. Previous clinical trials have documented the efficacy of some health functional foods; however, there are limitations. Studies on the potential roles and efficacy of some health functional foods, including caffeine, green tea, protein supplement, probiotics, and arginine, were reviewed. More large-scale and randomized placebo-controlled trials should be conducted eventually.

• 국제학술발표논문집
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• The 1th International Conference on Construction Engineering and Project Management
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• pp.377-382
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• 2005

The tools, methods and measures used for project control reflect underlying theories of management. Management theory has been neglected in the construction industry, which has rather focused on tools and neglected theory. This paper contributes to the theory of project management by introducing and developing two fundamental and competing conceptualizations of management: MBM (Managing-by-Means) and MBR (Managing-by-results). Current project control and performance measurement practice is based on MBR. However, project control based on MBR may not be appropriate for managing dynamic projects. The paper present the Last Planner^TM System (LPS) and Process Variance Control (PVC) as examples of methods reflecting the MBM view. It is argued first that the MBM view is appropriate for managing uncertain, complex and quick projects. The paper also explores how MBR tools and techniques may be appropriately used within an MBM framework.

• 셀메드
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• 제6권3호
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• pp.15.1-15.4
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• 2016

Evidence based practice (EBP) is a system of applying the most current and valid high quality evidence to support clinical decision making in a healthcare setting. In the twenty five years since its inception, EBP has become the accepted benchmark for excellence in healthcare. Although the system emerged within the biomedical sciences, in the years since EBP has become normative across all healthcare modalities from dentistry, allied health to complementary and alternative medicine (CAM). Practicing evidence based medicine within any modality potentially offers the patient the best available care based on high quality evidence. Yet it is the nature of the evidence that provokes some questions about the suitability of EBP across all modalities of healthcare. The meta analysis of randomized controlled trial (RCT) stands at the pinnacle of the hierarchy of evidence in EBP. This forms a challenge to CAM due to the difficulty in reducing the elementals of a holistic naturopathic assessment of a patient into an answerable question to be tested within a RCT. On one level this makes EBP paradigmatically incompatible with CAM, yet on another level it presents the opportunity to redefine the parameters of what is considered high level evidence. EBP has become a tool, and at times a weapon wielded by governments and health insurance companies to direct healthcare funding and policy. The implications of the nature of accepted evidence are becoming far reaching. The pursuit of the best available healthcare for each individual is the focus of EBP. However, the injudicious use of this system to direct health policy is fraught with biomedical bias and dominance. This issue raises the challenge to CAM to present high level evidence according to the rules of evidence, or face the annihilation of centuries of empirical knowledge.

• 동의생리병리학회지
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• 제22권4호
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• pp.918-929
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• 2008

This study investigated the effects of inverted position on EEG and heart rate variability before and after Bang song gong. BSG is a training method using in qi-gong and meditation to give a convergence of consciousness on body segments in order and take a silent speech of 'song'. The subjects were the 14 university students(n=7 per group) who had not experienced any medical problem and had not practiced BSG. They took a practice of the two way of BSG training program for 30 minutes every other day for two weeks. During practicing BSG, A group took sitting position and lean sitting position by turns, B group took inverted and lean sitting position in the same way. Statistical analysis conducted by two-way ANOVA($2groups^{\ast}2periods$) with p<0.05 for average difference of EEG and HR according to position change in each group before and after BSG. In A group, EEG and HR were changeless irrespective of the change of position and BSG. On the other hand, in B group, significant changes were observed in EEG(p<0.05). ${\alpha}$ wave of inverted position were on the increase, ${\beta}$ and ${\delta}$ wave of inverted position showed smaller power after two weeks training. In the variation of HR, there were smaller variation according to the position change after BSG compared to before BSG(p<0.05). The results suggested that an inverted position may make the depth of meditation deeper, and is likely to be effective for decreasing tension of brain and the sleepiness during qi-gong training. In addition to, an inverted position seemed to promote control of blood pressure of brain. So the application of an inverted position to 'BSG' will be very helpful to achieve deeper relaxation and to obtain the desired effect from qi-gong training.

• Nutrition Research and Practice
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• 제8권5호
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• pp.580-588
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• 2014

BACKGROUND/OBJECTIVES: The objective of the study was to provide useful insights into plain water intake of Korean adults according to life style, anthropometric, and dietary characteristics. SUBJECTS/METHODS: The data from the 2008-2010 Korea National Health and Nutrition Examination Survey were used. The subjects were 14,428 aged 20-64 years. Water intake was estimated by asking the question "How much water do you usually consume per day?". Dietary intake was estimated by 24-hour dietary recall. A qualitative food frequency questionnaire including 63 food items was also administered. RESULTS: The mean plain water intake for men and women were 6.3 cup/day and 4.6 cup/day, respectively. Plain water intake increased as lean body mass, waist circumference, and body mass index levels increased, except for percentage of body fat. As energy and alcohol intakes increased, plain water intake increased. As total weight of food intake and total volume of food intake increased, plain water intake increased. Plain water intake increased as consumption of vegetables increased. Plain water intake increased as frequencies of green tea, alcoholic drink, and all beverages were increased in men. Plain water intake increased with increased frequencies of green tea, milk, soy milk, and alcoholic drink and decreased frequencies of coffee and soda in women. CONCLUSIONS: Our results suggest that persons who had a higher waist circumference or lean body mass and women with higher BMI consumed more plain water. The persons eating high quality diet, or the persons who had more vegetables, green tea, milk, soy milk, or alcoholic drink consumed more plain water.