• Journal of Veterinary Science
• /
• 제21권2호
• /
• pp.27.1-27.10
• /
• 2020

The efficacies of a supraglottic airway device (SGAD) and an endotracheal tube (ETT) in cats under general anesthesia with volume-controlled ventilation (VCV) were compared. Thirty healthy cats were randomly allocated for airway control using either an SGAD or an ETT. Five tidal volumes (6, 8, 10, 12, and 14 mL/kg) were randomly tested, and respiratory rates were adjusted to achieve a minute ventilation of 100 mL/kg/min. The dose of propofol necessary to insert the SGAD or ETT, the static respiratory pressure, leakage during VCV, and end tidal CO₂ (ETCO₂) were recorded. Dosages of propofol and static respiratory measurements for the SGAD and ETT groups were compared using a t-test. The distribution of leakages and hypercapnia (ETCO₂ > 45 mmHg) were compared using Fisher's exact test. A significance level of p < 0.05 was established. No significant difference in dose of propofol was observed between the SGAD and ETT groups (7.1 ± 1.0, 7.3 ± 1.7 mg/kg; p = 0.55). Static resistance pressure of the SGAD (22.0 ± 8.1 cmH₂O/L/sec) was significantly lower than that of the ETT (36.6 ± 12.9 cmH₂O/L/sec; p < 0.01). Of the 75 trials, leakage was more frequent when using an SGAD (8 events) than when using an ETT (1 event; p = 0.03). Hypercapnia occurred more frequently with SGAD (18 events) than with ETT (3 events; p < 0.01). Although intubation with an ETT is the gold standard in small animal anesthesia, the use of an SGAD can reduce airway resistance and the work of breathing. Nonetheless, SGAD had more dead space and the tidal volume for VCV needs adjustment.

• Toxicological Research
• /
• 제11권2호
• /
• pp.199-203
• /
• 1995

The focus of this study was to investigate that cellular parameters and glucose uptake might be altered by extracellular calcium and starvation. Addition of 1 mM $Ca^{++}$ to hepatocytes (equalling to the free calcium concentration of blood) significantly increased intracellular $Na^+$ and decreased $Na^+$ & LDH leakage. This pertains to the hepatocytes of control rats as well as those of rats fasted for 24 and 48. hr. These effects might be come from the membrane-stabilizing effects of calcium. But calcium had no effects on cell volumes, superoxide-formation and glucose uptake. Actually hepatocytes of starved rats showed changes in several cellular parameters. Starvation increased LDH leakage, glucose uptake and the total concentration of $Na^+$ and $Na^+$ whereas it markedly decreased cell volumes. Since total tonicity remained unchanged, intracellular $Na^+$ and $Na^+$ could contribute to a higher share of total osmolarity in starvation. Starvation increased the cytoplasmic pH because $R-NH^{3+}$ions and their corresponding counterions disappeared. This increase may be related to suppress the protonization of amino groups in proteins. Starvation decreased hepatic glycogen, a major compound that affects cytosolic volume of hepatocytes. The data indicate that starvation increases the glucose transport activity. The possible molecular basis will be discussed.

• Journal of Advanced Marine Engineering and Technology
• /
• 제33권5호
• /
• pp.686-695
• /
• 2009

Flow characteristics in linear axial cascade have been studied using large eddy simulation(LES) based on finite element method(FEM) to investigate details of the leakage flow in the tip clearance of axial flow rotor. STAR-CD(FVM) and PAT-Flow(FEM) have been adopted to solve the Navier-Stokes equations for the simulation of the unsteady turbulent flow. Numerical results from the present study have been compared with the existing experimental results to investigate a tip clearance effect on velocity profile and static pressure distribution on blade surface at various spanwise positions. Both simulation results agree well with the experimental data. However, it has been shown that the results of finite-element large-eddy simulation agree better with experimental data than $k-{\varepsilon}$ turbulent model based on finite volume method regarding the tip vortex geometry and static pressure distribution at the center of the tip vortex core. As a result of this study, it is shown that finite-element large-eddy simulation method can predict more exactly on the tip leakage vortex flow and behind flow field.

• 유공압시스템학회논문집
• /
• 제4권3호
• /
• pp.1-6
• /
• 2007

The leakage generated from the clearance between the cylinder bore and the piston is one of the most serious problems in the hydraulic piston pump, and it even results in terrible decrease of the volume efficiency at a great velocity and high pressure. In this paper, the lubrication characteristic of the hydrostatic slipper bearing equipped in the hydraulic piston pump has been worked out by experimentation with three model bearings of different shape. Preparatory to this, not only the three models of piston-slipper were designed, but the corresponding experimental apparatus were also manufactured. As a result, it was verified that, according to the supply pressure, the hydrostatic bearing part of the slipper is severely affected by the pocket pressure, land pressure, oil film thickness, and leakage flow.

• 한국통신학회논문지
• /
• 제15권3호
• /
• pp.252-259
• /
• 1990

本 論文은 기존 LOCOS工程의 張點을 모두 겸비한 側面璧 SWAMI 技術에 대한 새로운 構造를 提示한다. 새로운 SWAMI공정은 순수 窒化膜 壓力과 體積 膨腸에 기인한 壓力을 크게 줄이기 위해서 側面璧 주위에 얇은 질화막과 反應性이온 飾刻으로 기울어진 실리콘 측면벽을 結合시켰따. 製作된 結果에 의하면, 缺陷이 없는 완전히 새부리 모양이 形成되지 않는 局地的 酸化 공정은 기울어진 面의 異方性 산화 隔離에 의해 實現시킬 수 있었다. 추가적인 마스크 段階는 要求되지 않는다. 이 工程에서 PN 다이오드의 漏泄電流는 기존 LOCOS 공정 보다 減少되었다. 한편 가장자리 部位는 漏泄電流 密度에서 평편한 接合 부위 보다 높게 分析되었다.

• Journal of Chest Surgery
• /
• 제19권2호
• /
• pp.217-224
• /
• 1986

Using an isolated rat heart preparation under both aerobic and ischemic condition, we observed the myocardial protective effect of verapamil cardioplegia. Isolated working hearts were subjected to global ischemia at 25oC. Before ischemic arrest, rat hearts were treated with cold potassium cardioplegic solution [K=30 mEq/L] in control group and cold potassium cardioplegic solution added with verapamil [1 mg/L] in other group. After 30 min. of ischemia, hemodynamic parameters and creatine kinase leakage in coronary effluent were observed. Verapamil group exhibited greater percent of recovery in aortic pressure [p<0.01], aortic flow [p<0.01], and stroke volume [p<0.05]. Although there were no significant difference in creatine kinase leakage and the percent recovery of cardiac output between verapamil and control group, verapamil group showed better myocardial function. But the time to recover regular sinus rhythm was significantly [p<0.001] prolonged in verapamil group.

• 드라이브 ㆍ 컨트롤
• /
• 제10권1호
• /
• pp.14-20
• /
• 2013

In the high rotational speed and pressure state, the leakage flow rate of the axial piston pump is one of the serious problems and make great reasons to decrease the volume efficiency. In this study, tribology characteristics is clarified for the hydrostatic slipper bearing in the swash plate type axial piston pump, by means of theoretical analysis for the different shape of the hydrostatic slipper bearing. It was analyzed by Mathcad software and used equal conditions at $0^{\circ}$ swash plate angle in each model. The results show that performance characteristics of the swash plate type axial piston pump are significantly influenced by the shape of the hydrostatic slipper bearing.

• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2002년도 추계학술대회논문초록집
• /
• pp.379.1-379
• /
• 2002

In this paper the leakage prediction and rotordynamic analysis of an annular seal with a smooth rotor and spiral-grooved stator are performed. For developing a theoretical model, the three-control-volume analysis of the circumferentially-grooved seal is expanded by considering pressure reduction due to the pumping effect of spiral groove and pressure flow through the spiral groove. Validation to the present analysis is achieved by comparisons with available experimental data. (omitted)

• 한방안이비인후피부과학회지
• /
• 제6권1호
• /
• pp.31-52
• /
• 1993

The object of thes research is to lucidate the clinical effects of Gami-Cheongshimyeonjayeum on the anti-allergic and gimmune response to rats and mice. The obtaind results of Gami-Cheongshimyeonjayeum administration are as follows : 1. The cytotoxic index increased slightly at over concentration $1{\times}10^{-2}/ml$, but it is thought that the cytotoxic effect show no significant value under the concentration $1{\times}10^{-3}/ml$. 2. Gami-Cheongshimyeonjayeum water extract seems to suppress the leakage volume of Evans blue to decrease the vascular permeability. 3. Gami-Cheongshimyeonjayeum show the inhibitory effect of footpad edema. 4. Protein leakage is inhibited by the administration of Gami-Cheongshimyeonjayeum. 5. The delayed type hypersensitivity to SRBC is suppressed at the 24hours after the administration of Gami-Cheongshimyeonjayeum on the experimental group 1, 2. 6. Hemolysin and hemagglutinin titer, and RFC increase to bulid up the immune function.

• 한국터널지하공간학회 논문집
• /
• 제23권6호
• /
• pp.439-449
• /
• 2021

최근 온실가스 저감과 더불어 저탄소배출 정책 등 환경오염에 관심이 증대되고 있다. 이에 따라 탄소배출을 저감할 수 있는 수소전지자동차를 비롯한 친환경 자동차의 보급률이 증가하고 있어 이에 대한 방재 및 안전관련 대책에 요구되고 있는 실정이다. 본 연구에서는 지하주차장의 장소에 국한하여 환기조건에 따라 수소연료자동차의 방출 시 수소의 농도 분포에 대한 위험정도를 수치해석을 통해 분석하였다. 그 결과, 수소탱크가 1개만 방출 될 경우 지하주차장 내 수소의 가연체적비는 최대 8.6%로 나타났으며, 환기가 지속적으로 이루어짐에 따라 연소가능한 수소의 체적비율은 150초 이후 1% 미만으로 감소되는 것으로 분석되어 기계적인 환기가 필수적인 것으로 분석되었다. 수소탱크 3개가 동시방출 또는 단계방출의 경우 최종적인 수소의 가연체적비율은 유사하지만 단계적으로 지연 방출함에 따라 방출 초기 수소의 가연체적비율의 증가폭이 낮은 것으로 나타났으며, 이에 따른 수소탱크 방출 시나리오의 추가적인 연구가 필요한 것으로 예상된다.