• Journal of Veterinary Science
• /
• v.21 no.2
• /
• pp.27.1-27.10
• /
• 2020

The efficacies of a supraglottic airway device (SGAD) and an endotracheal tube (ETT) in cats under general anesthesia with volume-controlled ventilation (VCV) were compared. Thirty healthy cats were randomly allocated for airway control using either an SGAD or an ETT. Five tidal volumes (6, 8, 10, 12, and 14 mL/kg) were randomly tested, and respiratory rates were adjusted to achieve a minute ventilation of 100 mL/kg/min. The dose of propofol necessary to insert the SGAD or ETT, the static respiratory pressure, leakage during VCV, and end tidal CO₂ (ETCO₂) were recorded. Dosages of propofol and static respiratory measurements for the SGAD and ETT groups were compared using a t-test. The distribution of leakages and hypercapnia (ETCO₂ > 45 mmHg) were compared using Fisher's exact test. A significance level of p < 0.05 was established. No significant difference in dose of propofol was observed between the SGAD and ETT groups (7.1 ± 1.0, 7.3 ± 1.7 mg/kg; p = 0.55). Static resistance pressure of the SGAD (22.0 ± 8.1 cmH₂O/L/sec) was significantly lower than that of the ETT (36.6 ± 12.9 cmH₂O/L/sec; p < 0.01). Of the 75 trials, leakage was more frequent when using an SGAD (8 events) than when using an ETT (1 event; p = 0.03). Hypercapnia occurred more frequently with SGAD (18 events) than with ETT (3 events; p < 0.01). Although intubation with an ETT is the gold standard in small animal anesthesia, the use of an SGAD can reduce airway resistance and the work of breathing. Nonetheless, SGAD had more dead space and the tidal volume for VCV needs adjustment.

• Toxicological Research
• /
• v.11 no.2
• /
• pp.199-203
• /
• 1995

The focus of this study was to investigate that cellular parameters and glucose uptake might be altered by extracellular calcium and starvation. Addition of 1 mM $Ca^{++}$ to hepatocytes (equalling to the free calcium concentration of blood) significantly increased intracellular $Na^+$ and decreased $Na^+$ & LDH leakage. This pertains to the hepatocytes of control rats as well as those of rats fasted for 24 and 48. hr. These effects might be come from the membrane-stabilizing effects of calcium. But calcium had no effects on cell volumes, superoxide-formation and glucose uptake. Actually hepatocytes of starved rats showed changes in several cellular parameters. Starvation increased LDH leakage, glucose uptake and the total concentration of $Na^+$ and $Na^+$ whereas it markedly decreased cell volumes. Since total tonicity remained unchanged, intracellular $Na^+$ and $Na^+$ could contribute to a higher share of total osmolarity in starvation. Starvation increased the cytoplasmic pH because $R-NH^{3+}$ions and their corresponding counterions disappeared. This increase may be related to suppress the protonization of amino groups in proteins. Starvation decreased hepatic glycogen, a major compound that affects cytosolic volume of hepatocytes. The data indicate that starvation increases the glucose transport activity. The possible molecular basis will be discussed.

• Journal of Advanced Marine Engineering and Technology
• /
• v.33 no.5
• /
• pp.686-695
• /
• 2009

Flow characteristics in linear axial cascade have been studied using large eddy simulation(LES) based on finite element method(FEM) to investigate details of the leakage flow in the tip clearance of axial flow rotor. STAR-CD(FVM) and PAT-Flow(FEM) have been adopted to solve the Navier-Stokes equations for the simulation of the unsteady turbulent flow. Numerical results from the present study have been compared with the existing experimental results to investigate a tip clearance effect on velocity profile and static pressure distribution on blade surface at various spanwise positions. Both simulation results agree well with the experimental data. However, it has been shown that the results of finite-element large-eddy simulation agree better with experimental data than $k-{\varepsilon}$ turbulent model based on finite volume method regarding the tip vortex geometry and static pressure distribution at the center of the tip vortex core. As a result of this study, it is shown that finite-element large-eddy simulation method can predict more exactly on the tip leakage vortex flow and behind flow field.

• Transactions of The Korea Fluid Power Systems Society
• /
• v.4 no.3
• /
• pp.1-6
• /
• 2007

The leakage generated from the clearance between the cylinder bore and the piston is one of the most serious problems in the hydraulic piston pump, and it even results in terrible decrease of the volume efficiency at a great velocity and high pressure. In this paper, the lubrication characteristic of the hydrostatic slipper bearing equipped in the hydraulic piston pump has been worked out by experimentation with three model bearings of different shape. Preparatory to this, not only the three models of piston-slipper were designed, but the corresponding experimental apparatus were also manufactured. As a result, it was verified that, according to the supply pressure, the hydrostatic bearing part of the slipper is severely affected by the pocket pressure, land pressure, oil film thickness, and leakage flow.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.15 no.3
• /
• pp.252-259
• /
• 1990

This paper present new scheme for a Side Wall Masked Isolation(SWAMI) technology which take all the advatages provided by conventional LOCOS process. A new SWAMI process incorporates a sloped sidewall by reactive ion etch and a layer of thin nitride around the side walls such that both intrinsic nitride stress and volume expansion induced stress are greatly reduced. As a fabricate results, a defect-free fully recessed zero bird's beak local oxidation process can be realized by the sloped wall anisotropic oxide isolation. No additional masking step is required. The leakage current of PN diodes of this process were reduced than PN diode of conventional LOCOS process. On the other hand, the edge junction part was larger than the flat juction part in the density of leakage current.

• Journal of Chest Surgery
• /
• v.19 no.2
• /
• pp.217-224
• /
• 1986

Using an isolated rat heart preparation under both aerobic and ischemic condition, we observed the myocardial protective effect of verapamil cardioplegia. Isolated working hearts were subjected to global ischemia at 25oC. Before ischemic arrest, rat hearts were treated with cold potassium cardioplegic solution [K=30 mEq/L] in control group and cold potassium cardioplegic solution added with verapamil [1 mg/L] in other group. After 30 min. of ischemia, hemodynamic parameters and creatine kinase leakage in coronary effluent were observed. Verapamil group exhibited greater percent of recovery in aortic pressure [p<0.01], aortic flow [p<0.01], and stroke volume [p<0.05]. Although there were no significant difference in creatine kinase leakage and the percent recovery of cardiac output between verapamil and control group, verapamil group showed better myocardial function. But the time to recover regular sinus rhythm was significantly [p<0.001] prolonged in verapamil group.

• Journal of Drive and Control
• /
• v.10 no.1
• /
• pp.14-20
• /
• 2013

In the high rotational speed and pressure state, the leakage flow rate of the axial piston pump is one of the serious problems and make great reasons to decrease the volume efficiency. In this study, tribology characteristics is clarified for the hydrostatic slipper bearing in the swash plate type axial piston pump, by means of theoretical analysis for the different shape of the hydrostatic slipper bearing. It was analyzed by Mathcad software and used equal conditions at $0^{\circ}$ swash plate angle in each model. The results show that performance characteristics of the swash plate type axial piston pump are significantly influenced by the shape of the hydrostatic slipper bearing.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2002.11a
• /
• pp.379.1-379
• /
• 2002

In this paper the leakage prediction and rotordynamic analysis of an annular seal with a smooth rotor and spiral-grooved stator are performed. For developing a theoretical model, the three-control-volume analysis of the circumferentially-grooved seal is expanded by considering pressure reduction due to the pumping effect of spiral groove and pressure flow through the spiral groove. Validation to the present analysis is achieved by comparisons with available experimental data. (omitted)

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.6 no.1
• /
• pp.31-52
• /
• 1993

The object of thes research is to lucidate the clinical effects of Gami-Cheongshimyeonjayeum on the anti-allergic and gimmune response to rats and mice. The obtaind results of Gami-Cheongshimyeonjayeum administration are as follows : 1. The cytotoxic index increased slightly at over concentration $1{\times}10^{-2}/ml$, but it is thought that the cytotoxic effect show no significant value under the concentration $1{\times}10^{-3}/ml$. 2. Gami-Cheongshimyeonjayeum water extract seems to suppress the leakage volume of Evans blue to decrease the vascular permeability. 3. Gami-Cheongshimyeonjayeum show the inhibitory effect of footpad edema. 4. Protein leakage is inhibited by the administration of Gami-Cheongshimyeonjayeum. 5. The delayed type hypersensitivity to SRBC is suppressed at the 24hours after the administration of Gami-Cheongshimyeonjayeum on the experimental group 1, 2. 6. Hemolysin and hemagglutinin titer, and RFC increase to bulid up the immune function.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.23 no.6
• /
• pp.439-449
• /
• 2021

The recent reduction in greenhouse gases, interest in environmental pollution such as low-carbon emission policies is increasing. Accordingly, the penetration rate of eco-friendly vehicles, including hydrogen battery vehicles capable of reducing carbon emission, is increasing, and thus it is required for disaster prevention and safety-related measures. In this study, the degree of risk for the concentration distribution of hydrogen when leaking hydrogen fuel vehicles according to ventilation conditions was analyzed through numerical analysis, limited to places in parking lots. As a result, when only one hydrogen tank was released, the combustible volume ratio of hydrogen in the underground parking lot was up to 8.6%, and as ventilation continued, the volume ratio of combustible hydrogen decreased to less than 1% after 150 seconds, indicating that mechanical ventilation is essential. In the case of simultaneous release or stage release of three hydrogen tanks, the final combustible volume ratio of hydrogen is similar, but the increase in the combustible volume ratio of hydrogen in the early stage of release is low, and further research is expected.