• Journal of the Korean Society of Food Culture
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• v.35 no.2
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• pp.224-232
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• 2020

Glaucoma is one of the leading causes of blindness worldwide and is characterized by degeneration of the optic nerve. Elevated intraocular pressure (IOP) is the major contributing factor to optic nerve damage. However, some patients develop glaucoma even with normal IOP. Other factors, including age, race, myopia, and nutrition, can affect glaucoma risk. Dietary fat intake and serum fatty acid composition are closely related with the fatty acid profile of the retina and thus can modulate glaucoma risk. In this study, we collected serum samples from 34 glaucoma patients (26 primary open angle glaucoma (POAG) and 8 normal tension glaucoma (NTG)) and 45 healthy controls and analyzed their serum phospholipid fatty acid concentrations. The results show that the ratio of oleic acid to stearic acid (OA/SA), which is an indicator of stearoyl-CoA desaturase activity, was higher in POAG patients when compared to normal controls. The ratio of eicosapentaenoic acid to arachidonic acid (EPA/AA), which is an indirect marker of eicosanoid biosynthesis, was also higher in glaucoma patients (p=0.048). These results imply that dietary fatty acid intake and serum fatty acid profile can influence glaucoma risk. Additional study is necessary to identify the relationship between fatty acids and glaucoma.

• Journal of the Korean Institute of Landscape Architecture
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• v.35 no.5
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• pp.37-45
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• 2007

WTO/TBT requires that, for technical regulations affecting trade, technical regulatory requirements must be specified where possible in terms of performance rather than design or descriptive characteristics. The movement which made "performance" a keyword in landscape architecture was activated in Japan, one of the leading counties in performance-based regulatory system(PBRS). The Japanese recent movement of systematization activity on performance-based standards and specifications was reviewed and operational applications for performance-based regulatory system in South Korea are summarized as follows: 1. The establishment of performance standards that can be properly evaluated by assessment indicators is necessary in cases when quantitative evaluation is difficult. 2. As a preparation for PBRS, a brief procurement system by technical proposal for the landscape design and construction is necessary. 3. As a preparation for PBRS, activation of an environmental performance evaluation on experimental construction is necessary. 4. As a preparation for PBRS, a certification system of environmental performance on various landscape construction methods is necessary. 5. The Private Finance Initiative Project is the most similar to PBRS therefore, activation of the Private Finance Initiative Project is necessary in landscape architecture projects for park rehabilitation.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2015.05a
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• pp.192-193
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• 2015

The number of accidents is raising every year and severity is also increasing. A lot of studies are interested in the leading indicator such as safety culture or safety audit to reduce accidents. In particular, the studies on safety awareness are actively conducted. However, these studies showed that there was consciousness of scapegoatism which to pass responsibility of accident causes to others regardless of safety awareness. It means that there are probability about overestimating and making light of unsafe condition and act which have to manage and control. Eventually, the direct causes which lead to the fatal accident may be consistently arisen. Nevertheless, researches about consciousness of scapegoatism are shortage. Therefore, this study proposed the means to investigate the relationship between consciousness of scapegoatism and accidents through report from KOSHA and conducts the survey with suggested means. This paper will contribute to prevent accidents by identifying relationship between consciousness of scapegoatism and accidents.

• Journal of Ginseng Research
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• v.21 no.1
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• pp.61-67
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• 1997

The present study examined the characteristics of behavior Induced by dopamine agonists following treatment with 6-hydroxydopamine(6-OHDA) unilaterally into left striatum in rats. 6-OHDA was administered at doses of 8,16 and 24 $\mu\textrm{g}$/$\mu\textrm{l}$(in 0.1% ascorbic acid) into dopaminergic neurons in left striatum of 7 weeks old rat under anesthetic. Locomotor activity was significantly decreased at 1 week following 6-OHDA-administration in 7 weeks old rats. The contralateral circling behavior was induced by apomorphine(5 mg/kg, i.v.) after 1 week following 6-OHDA(24$\mu\textrm{g}$/$\mu\textrm{l}$) treatment, and was further increased by repeated administration of apomorphine at 2, 3 and 4 weeks. The contralateral circling behavior was also induced by lisuride and 1-dopa in a dose dependent manner, but not by SK & F 82526 in 7 weeks old rats treated with 6-OHDA. The contralateral circling behavior was significantly higher in 21 weeks old rats but significantly lower In 35 weeks old rats when compared with 7 weeks old rats. The contralateral circling behavior induced by apomorphlne did not differ significantly in 7 and 35 weeks old male and female rats. These results suggest that 6-OHDA treatment into left striatum causes remarkable destrurtion of intrastriatal dopaminergic netcons leading to dopaminergic receptor supersensitivity. Thus, the contralateral circling behavior in duces by apomorphine may be used as indicator for neurodegenerative diseases.

• Journal of The Korean Society of Agricultural Engineers
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• v.55 no.4
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• pp.45-53
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• 2013

Efficient water operation and management of an irrigation system plays an important element in the sustainability of irrigated agriculture. An agricultural water is delivered in many open canals of irrigation delivery system by reservoirs. The poor water distribution and management in an irrigation system is a major factor leading to low water efficiency. It is necessary to compare the estimated irrigation demands with the actual water supplies for decision making to maintain the water supply according to demand strategy. Smarter water management, new technologies and improvement of water management system, is essential to solve the problem of water efficiency and availability. In this paper, the irrigation efficiencies according to water delivery performance indicator were measured with automatic water gauge at irrigation canals, and calculated from spatial and temporal distribution of water supply for the lack of planning in water delivery. The analysis of results are obtain an insight into possible improvement methods to develop canal water management policies that enable irrigation planners to optimally manage scarce available water resources.

• Journal of Distribution Science
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• v.17 no.1
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• pp.11-19
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• 2019

Purpose - We document the impact of economic policy uncertainty (EPU) in the US and China on the dynamic spillover effect of macroeconomics such as stock price, housing price in Korea. Research design, data, and methodology - We use the nine variables to analyze the effect which produces a result among the EPU indexes of the US and China on economic variables which is the consumer price index (CPI), housing purchase price composite index, housing lease price, the stock price index in banking industry, construction industry and distribution industry, and composite leading indicator from January 1995 to December 2016 with the Vector Error Correction Model. Result - The US EPU index has significantly a negative relation on the CPI, housing purchase price index, housing lease price index, the stock price index in banking industry, construction industry, and distribution industry in Korea. Conclusions - We find the dynamic effect of the EPU indexes in the US and China on the macroeconomics returns in Korea. This study has an empirical evidence that the economy market in Korea is influenced by the EPU index of the US rather than it of China. The higher EPU, the more risky the economy of in Korea.

• Journal of Distribution Science
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• v.18 no.12
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• pp.67-77
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• 2020

Purpose: Based on the author's adapted invariant choice, this study is to present the methodology and the calculation of the integral index of the digital component of the quality of life. By analyzing the digital indexes, the study is also to discuss distribution of ICT and the digital quality of life of the population of Kazakhstan and its regions. Research design, data, methodology: In this research, the method of calculation of integral assessment of the indicator was used, which indicates index constructs. The study analyzed objective secondary data for the period 2017-2019, which was the database from official websites of the Committee on Statistics of the Republic of Kazakhstan. Results: The study produced an integral code for assessing digital components of living standards of the population, consisting of five groups sub-indexes. Conclusions: Based on the provided analyses, we can confirm the existence of a significant difference of all the indicators of digital living standards of the population between the two leading cities: Almaty city and Nur-Sultan city. Furthermore we can deduce the differences of the examined indexes for other regions of Kazakhstan. Despite the rapid adoption of digital technologies, Kazakhstan still has significant digital gaps among cities indicating regional differences in the speed of implementation and distribution of digital technologies.

• BMB Reports
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• v.54 no.6
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• pp.295-304
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• 2021

Olfactory neuropathology is a cause of olfactory loss in Alzheimer's disease (AD). Olfactory dysfunction is also associated with memory and cognitive dysfunction and is an incidental finding of AD dementia. Here we review neuropathological research on the olfactory system in AD, considering both structural and functional evidence. Experimental and clinical findings identify olfactory dysfunction as an early indicator of AD. In keeping with this, amyloid-β production and neuroinflammation are related to underlying causes of impaired olfaction. Notably, physiological features of the spatial map in the olfactory system suggest the evidence of ongoing neurodegeneration. Our aim in this review is to examine olfactory pathology findings essential to identifying mechanisms of olfactory dysfunction in the development of AD in hopes of supporting investigations leading towards revealing potential diagnostic methods and causes of early pathogenesis in the olfactory system.

• Journal of the Korean Society of Safety
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• v.37 no.6
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• pp.32-39
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• 2022

This study analyzed the relationship between occupational accidents in the construction industry and business cycle factors. Multiple regression analyses were conducted to achieve the research purpose; additionally, time-varying parameter estimations were performed to interpret the results. The results obtained for the construction industry revealed a statistically significant relationship between occupational accidents and wage increase rate, unemployment, construction starts, and other factors. The wage increase rate plays a role in reducing occupational accidents because efforts are made to prevent accidents owing to the increase in income loss due to accidents and the demand for increased safety levels. The number of construction starts affects occupational accidents with a time lag of 1 to 2 or 4 months; therefore, it is likely to be used as a leading indicator for estimating fatal accidents in the construction industry. This study highlighted the importance of monitoring socioeconomic changes that could affect the working conditions of workers and workplaces, and production activities in the workplace for the effective prevention of occupational accidents. This study also reveals the necessity of developing a method to operate prevention projects flexibly and the seasonality of industrial characteristics, particularly those of the construction industry where the highest number of fatal occupational injuries occur.

• Structural Engineering and Mechanics
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• v.81 no.2
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• pp.195-203
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• 2022

This paper presents the quantification and location damage detection of plane and space truss structures in a two-phase method to reduce the computations efforts significantly. In the first phase, a proposed damage indicator based on the residual force vector concept is used to get the suspected damaged members. In the second phase, using damage quantification as a variable, a teaching-learning based optimization algorithm (TLBO) is used to obtain the damage quantification value of the suspected members obtained in the first phase. TLBO is a relatively modern algorithm that has proved distinguished in solving optimization problems. For more verification of TLBO effeciency, the classical particle swarm optimization (PSO) is used in the second phase to make a comparison between TLBO and PSO algorithms. As it is clear, the first phase reduces the search space in the second phase, leading to considerable reduction in computations efforts. The method is applied on three examples, including plane and space trusses. Results have proved the capability of the proposed method to precisely detect the quantification and location of damage easily with low computational efforts, and the efficiency of TLBO in comparison to the classical PSO.