• Molecules and Cells
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• v.41 no.8
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• pp.705-716
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• 2018

The endoplasmic reticulum (ER) is a critical organelle for protein synthesis, folding and modification, and lipid synthesis and calcium storage. Dysregulation of ER functions leads to the accumulation of misfolded- or unfolded-protein in the ER lumen, and this triggers the unfolded protein response (UPR), which restores ER homeostasis. The UPR is characterized by three distinct downstream signaling pathways that promote cell survival or apoptosis depending on the stressor, the intensity and duration of ER stress, and the cell type. Mammalian cells express the UPR transducers IRE1, PERK, and ATF6, which control transcriptional and translational responses to ER stress. Direct links between ER stress and immune responses are also evident, but the mechanisms by which UPR signaling cascades are coordinated with immunity remain unclear. This review discusses recent investigations of the roles of ER stress in immune responses that lead to differentiation, maturation, and cytokine expression in immune cells. Further understanding of how ER stress contributes to the pathogenesis of immune disorders will facilitate the development of novel therapies that target UPR pathways.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2017.11a
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• pp.122-123
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• 2017

As the building is becomes bigger and larger, it can lead to big damage in case of fire. Also, tunnel, machine room and underground joint are spaces that can cause high temperature fire above 1,350℃ in case of fire. Therefore, a refractory material is need that can be withstand in high temperatures for long time. One side, the composition of oyster shell is CaCO₃ of 90% or more. It is expected that it will be possible to use it as a high calcium natural material which is the material of the refractory board. According to, Study on bending, compressive strength of mortar according to temperature and heating time change using classified oyster shell as aggregate.

• Advances in concrete construction
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• v.4 no.4
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• pp.305-317
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• 2016

Porous materials such as concrete could be subjected to aggressive ions transport. Durability of cement paste is extremely depended on water and ions penetration into its interior sections. These ions transport could lead different damages depending on reactivity of ions, their concentrations and diffusion coefficients. In this paper, chloride diffusion process in cement hydrates is simulated at atomistic scale using molecular dynamics. Most important phase of cement hydrates is calcium silicate hydrate (C-S-H). Tobermorite, one of the most famous crystal analogues of C-S-H, is used as substrate in the simulation model. To conduct simulation, a nanopore is considered in the middle of simulation cell to place water molecules and aggressive ions. Different chloride salts are considered in models to find out which one is better for calculation of the transport properties. Diffusion coefficients of water molecules and chloride ions are calculated and validated with existing analytical and experimental works. There are relatively good agreements among simulation outputs and experimental results.

• Journal of Plant Biology
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• v.20 no.1
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• pp.45-52
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• 1977

During the period of 1975-76, a survey was carried out to find out zinc indicators in the natural vegetation in Korea. The symptoms fo chlorosis were observed in flowering plants in the areas of zinc outcrop of Wolgok-A, Seokgok-9, and Sowolgok. Although 28 species were found to be chlorotic, the total quantity of chlorotic foliage observed was small. Reasons for chlorosis in the areas of zinc are deposits is considered as effects of zinc, lead, copper and calcium ions. Sedum sp. and Dianthus sinensis were confined to soil containing more than exchangeable zinc of 30 ppm and to accumulation in the plants contained at least 1,300-14,000 ppm of zinc. Therefore Sedum sp. and Dianthus sinensis might be used as zinc indicators in Korea.

• The Journal of the Korean dental association
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• v.57 no.8
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• pp.464-473
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• 2019

For dental pulp treatment of immature permanent teeth, direct pulp capping or partial/cervical pulpotomy (apexogenesis) procedures can be used if the dental pulp is vital. MTA (Mineral Trioxide Aggregate) is regarded as the first choice dressing material for these procedures because its higher success rate. It can be also used successfully for devitalized dental pulp which has been treated by calcium hydroxide. This apexification procedure with MTA has a few advantage such as short treatment period and increase of resistance against root fracture. Recently, regenerative endodontic treatment was introduced for devitalized immature pulp. It can maintain pulp vitality and lead to continuing root development although the dental pulp was devitalized.

• Journal of The Korean Astronomical Society
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• v.29 no.spc1
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• pp.317-319
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• 1996

Utilizing a Calcium filter, a large two ribbon flare of an importance 2.5Xj31? was recorded at. King Abdul-Aziz University Solar Observatory (KAAUSO) at the 30th of October 1991. This chromosphenc flare observation, which is of special importance since it is rarely reported, was for a flare that occurred near the south west of the equator at the vicinity of a large sunspot group on an active region known as AR 6891. The observed foot points of this flare had a strange behavior in which the separating motion of the ribbons were not typical of most flares, rather were nearly orthogonal. In this article we present the characteristics of the main sunspot group of this active region and try to investigate its evolution and fragmentation with time. Information regarding magnetic fields and velocity fields are necessary to understand the restructuring of the magnetic field pattern and plasma motion, and hence the changes that could lead to the occurrence of such an interesting flare.

• Progress in Superconductivity and Cryogenics
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• v.10 no.1
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• pp.62-66
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• 2008

The characteristic of the superconducting magnetic energy storage(SMES) system is faster response, longer life time, more economical, and environment friendly than other uninterruptible power supply(UPS) using battery. So, the SMES system can be used to develop methods for improving power quality where a short interruption of power could lead to a long and costly shutdown. Recently, cryogen free SMES has developed using BSCCO(Bismuth Strontium Calcium Copper Oxide) wire. We fabricated and tested the conduction cooling system for the 600 kJ class HTS SMES. The experiment was accomplished for the simulation coils. The simulation coils were made of aluminium, it is equivalent to thermal mass of 600 kJ HTS SMES coil. The coil is cooled with two GM coolers through the copper conduction bar. In this paper, we report that the test results of cool-down and heat loads characteristics of the simulation coils. The developed conduction cooling system adapted to 600 kJ HTS SMES system and cope with the unexpected sudden heat impact, too.

• International Journal of Oral Biology
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• v.49 no.2
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• pp.34-41
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• 2024

Extracellular traps (ETs), primarily composed of DNA and antibacterial peptides, are mainly secreted by neutrophils to inhibit pathogen spread and eliminate microorganisms. Recent reports suggest that microglia can also secrete ETs, and these microglial ETs are associated with various neurological conditions, including nerve injury, tumor microenvironment, and ischemic stroke. However, the components and functions of microglial ETs remain underexplored. Secretagogin (Scgn), a calcium-sensor protein, plays a crucial role in the release of peptide hormones, such as insulin, in endocrine cells; however, its function in immune cells, including microglia, is not well understood. Our study demonstrated that Scgn deficiency can lead to the formation of abnormal ETs. We hypothesized that this may involve the c-Jun N-terminal kinase-myeloperoxidase pathway and autophagy.

• Biomedical Science Letters
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• v.5 no.1
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• pp.119-129
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• 1999

This study was aimed to investigate the enzyme-histochemical localization and characteristics of alkaline and acid phosphatase extracted from adult of Echinostoma hortense. Using the Gomori calcium stain and the Gomori lead nitrate satin method, we found that the alkaline and acid phosphatases were localized mostly in the intestine, vitellaria and pharynx of Echinostoma hortense. The three isozymes of alkaline phosphatase and two isozymes of acid phosphatase were separated from Echinostoma hortense by electrophoresis. The isozymes of alkaline phosphatase were 145.9, 207.5, 220.8 kDa and the isozymes of acid phosphatase were 179.5 and 209.4 kDa. The activity of alkaline phosphatase was denatured completely after heating at 9$0^{\circ}C$ for 12 seconds. The optimum pH and temperature for activity of alkaline phosphatase were about pH 9 and 4$0^{\circ}C$, while the optimum pH for activity of acid phosphatase was about pH 5. The maximum activity of alkaline phosphatase was at 189 unit, but maximum activity of acid phosphatase was at 71 unit As the result from above, we observed that alkaline and acid phosphatases funtion mainly in the alimentary tract and vitellaria. Echinostoma hortense performs the parasitism in the intestine of host by using proper isozyme of phosphatase.

• Journal of Korea Society of Waste Management
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• v.35 no.7
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• pp.670-682
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• 2018

Engineered nanomaterials (ENMs) can be released to humans and the environment through the generation of waste containing engineered nanomaterials (WCNMs) and the use and disposal of nano-products. Nanoparticles can also be introduced intentionally or unintentionally into waste streams. This study examined WCNMs in domestic industries, and target nanomaterials, such as silicon dioxide, titanium oxide, zinc oxide, nano silver, and carbon nanotubes (CNTs), were selected. We tested 48 samples, such as dust, sludge, ash, and by-products from manufacturing facilities and waste treatment facilities. We analyzed leaching and content concentrations for heavy metals and hazardous constituents of the waste. Chemical compositions were also measured by XRD and XRF, and the unique properties of nano-waste were identified by using a particle size distribution analyzer and TEM. The dust and sludge generated from manufacturing facilities and the use of nanomaterials showed higher concentrations of metals such as lead, arsenic, chromium, barium, and zinc. Oiled cloths from facilities using nano silver revealed high concentrations of copper, and the leaching concentrations of copper and lead in fly ash were higher than those in bottom ash. In XRF measurements at the facilities, we detected compounds such as silicon dioxide, sulfur trioxide, calcium oxide, titanium dioxide, and zinc oxide. We found several chemicals such as calcium oxide and silicon dioxide in the bottom ash of waste incinerators.