• 제목/요약/키워드: Layer potentials

검색결과 127건 처리시간 0.025초

Developmental Switch of the Serotonergic Role in the Induction of Synaptic Long-term Potentiation in the Rat Visual Cortex

  • Park, Sung-Won;Jang, Hyun-Jong;Cho, Kwang-Hyun;Kim, Myung-Jun;Yoon, Shin-Hee;Rhie, Duck-Joo
    • The Korean Journal of Physiology and Pharmacology
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    • 제16권1호
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    • pp.65-70
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    • 2012
  • Synaptic long-term potentiation (LTP) and long-term depression (LTD) have been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of LTP and LTD during the critical period of the rat visual cortex (postnatal 3~5 weeks). However, in adult rats, the increase in 5-HT level in the brain by the administration of the selective serotonin reuptake inhibitor (SSRI) fluoxetine reinstates ocular dominance plasticity and LTP in the visual cortex. Here, we investigated the effect of 5-HT on the induction of LTP in the visual cortex obtained from 3- to 10-week-old rats. Field potentials in layer 2/3, evoked by the stimulation of underlying layer 4, was potentiated by theta-burst stimulation (TBS) in 3- and 5-weekold rats, then declined to the baseline level with aging to 10 weeks. Whereas 5-HT inhibited the induction of LTP in 5-week-old rats, it reinstated the induction of N-methyl-D-aspartate receptor (NMDA)-dependent LTP in 8- and 10-week-old rats. Moreover, the selective SSRI citalopram reinstated LTP. The potentiating effect of 5-HT at 8 weeks of age was mediated by the activation of 5-$HT_2$ receptors, but not by the activation of either 5-$HT_{1A}$ or 5-$HT_3$ receptors. These results suggested that the effect of 5-HT on the induction of LTP switches from inhibitory in young rats to facilitatory in adult rats.

Post Ru CMP Cleaning for Alumina Particle Removal

  • Prasad, Y. Nagendra;Kwon, Tae-Young;Kim, In-Kwon;Park, Jin-Goo
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2011년도 춘계학술발표대회
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    • pp.34.2-34.2
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    • 2011
  • The demand for Ru has been increasing in the electronic, chemical and semiconductor industry. Chemical mechanical planarization (CMP) is one of the fabrication processes for electrode formation and barrier layer removal. The abrasive particles can be easily contaminated on the top surface during the CMP process. This can induce adverse effects on subsequent patterning and film deposition processes. In this study, a post Ru CMP cleaning solution was formulated by using sodium periodate as an etchant and citric acid to modify the zeta potential of alumina particles and Ru surfaces. Ru film (150 nm thickness) was deposited on tetraethylorthosilicate (TEOS) films by the atomic layer deposition method. Ru wafers were cut into $2.0{\times}2.0$ cm pieces for the surface analysis and used for estimating PRE. A laser zeta potential analyzer (LEZA-600, Otsuka Electronics Co., Japan) was used to obtain the zeta potentials of alumina particles and the Ru surface. A contact angle analyzer (Phoenix 300, SEO, Korea) was used to measure the contact angle of the Ru surface. The adhesion force between an alumina particle and Ru wafer surface was measured by an atomic force microscope (AFM, XE-100, Park Systems, Korea). In a solution with citric acid, the zeta potential of the alumina surface was changed to a negative value due to the adsorption of negative citrate ions. However, the hydrous Ru oxide, which has positive surface charge, could be formed on Ru surface in citric acid solution at pH 6 and 8. At pH 6 and 8, relatively low particle removal efficiency was observed in citric acid solution due to the attractive force between the Ru surface and particles. At pH 10, the lowest adhesion force and highest cleaning efficiency were measured due to the repulsive force between the contaminated alumina particle and the Ru surface. The highest PRE was achieved in citric acid solution with NaIO4 below 0.01 M at pH 10.

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지반정보 분석 및 평가를 위한 웹기반 지리공간정보 시스템 개발 (Development of a Web-based Geospatial Information System for Analyzing and Assessing Geotechnical Information)

  • 이상훈;장용구
    • 한국지리정보학회지
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    • 제10권4호
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    • pp.142-152
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    • 2007
  • 지반정보DB는 NGIS 2단계 기본계획의 하나인 '지하지리정보'구축의 기초자료로써, 건설교통부가 2000년부터 전국토를 대상으로 구축하고 있다. 구축된 지반정보는 지층의 심도, 종류, 색 및 지하수위 등 지하의 상태정보 뿐만 아니라, 표준관입시험, 압축시험 등의 건설공사 설계업무에 적용가능한 공학정보를 포함하고 있다. 그러나 현재는 시험 결과서만 제공되고 있기 때문에 공학업무의 지반의 해석 및 설계에 활용하기 어려운 실정이다. 본 연구는 지반정보DB의 효과적인 활용지원을 위하여 웹기반의 지리공간정보 시스템을 개발하였다. 먼저, 지반정보DB에서 공간정보, 지층정보 및 공학 시험정보를 실시간으로 불러와 지반단면모델을 생성하고, 이를 통해 해당 지반의 토공량, 지지력, 침하량을 산정하고, 연약지반, 액상화에 대한 평가를 수행하는 웹 클라이언트를 개발하였다. 본 시스템을 통해 지반정보 DB를 건설공사의 계획 및 설계 등 실무 전반에 적극 활용할 수 있을 것이다.

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무선랜 시스템에서 전이중 통신을 위한 MAC 프로토콜 분석 (Medium Access Control Protocols for Full-Duplex Communications in WLAN Systems: Approaches and Challenges)

  • 김원중;송태원;김태윤;백상헌
    • 한국통신학회논문지
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    • 제40권7호
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    • pp.1276-1285
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    • 2015
  • 최근 들어, 자기 간섭 제어 기술의 발달로 인하여 PHY 계층에서는 full-duplex 통신이 가능한 수준에 도달하였다. 이러한 full-duplex 통신을 지원하기 위한 다양한 MAC 계층의 기술들이 활발히 연구 중이다. 본 논문에서는 무선랜 (WLAN) 시스템에서 full-duplex 통신의 특징과 이로 인하여 발생하는 문제점들을 알아보고, 이 문제를 해결하기 위하여 제안된 다양한 MAC 프로토콜을 살펴본다. 그리고 현재 초기 단계에 있는 무선랜 시스템에서의 full-duplex 통신과 관련된 MAC 계층의 향후 연구 과제를 논의한다.

Glutaraldehyde계 상아질 과민증 탈감작제에 의한 치수신경 활동성 변화 및 상아세관 폐쇄양상 (CHANGES IN INTRAPULPAL NERVE ACTIVITY AND OCCLUDING ASPECTS OF DENTINAL TUBULES BY DENTIN DESENSITIZER CONTAINING GLUTARALDEHYDE)

  • 김종화;이광원;손호현
    • Restorative Dentistry and Endodontics
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    • 제21권2호
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    • pp.505-516
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    • 1996
  • The effects of application of dentin desensitizer containing glutaraldehyde (Gluma Desensitizer) and dentin adhesive system (All Bond 2) to the exposed dentin on the intradental nerve activity (INA) and the occluding aspects of dentinal tubules were investigated in cat canine teeth. Single pulp nerve units were dissected from the inferior alveolar nerve and indentified as $A{\delta}$-fiber units. The INAs elicited by 4M NaCl before and after the application of each experimental agent were compared. The morphological changes of exposed dentin surfaces and dentinal tubules in the dentin specimens used to record INAs were observed by SEM. The results obtained were as follows. 1. Eight $A{\delta}$-fiber units (conduction velocity: $8.0{\pm}4.0m$/sec) were identified. 4M NaCl evoked an irregular burst of action potentials which ceased immediately after washing. 2. In 4 $A{\delta}$-fiber units, the change of INA after the application of Gluma Desensitizer was $133.9{\pm}80.7%$ when it was compared with the INA before the application of the same agent. 3. In 4 $A{\delta}$-fiber units, application of All Bond 2 completely abolished the INA induced by 4M NaCl. 4. In specimens applied with Gluma Desensitizer, the formation of hybrid layer as well as the identification of resin penetration and reaction products with proteins in dentinal tubules were not clearly observed in interface between dentin and adhesive resin. In specimens applied with All Bond 2, the gap width of 2-$3{\mu}m$ was formed between exposed dentin and adhesive resin, and the hybrid layer and resin tags were not clearly formed either.

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Isolation of antifungal compounds from Helicosporium nizamabadense KCTC 0635BP

  • Kim, Ki-Wook;Bae, Yun-Ui;Yoo, Ju-Soon;Cho, Su-Dong;Moon, Ja-Young;Kim, Dong-Wan;Jeong, Yong-Kee;Joo, Woo-Hong
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2003년도 생물공학의 동향(XIII)
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    • pp.415-419
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    • 2003
  • One strain was isolated from wilted chestnut tree and identified as Helicosporium nizamabadense. Also, the strain was evaluated for biocontrol potentials against phytopathogens. Autoclaved fraction of the isolate also showed complete growth inhibition of the turfgrass large patch pathogen, Rhizoctonia. solani AG2-2 and plant pathogen, Botrytis cinerea. Culture extracts of Helicosporium nizamabadense were purified by Thin Layer Chromatography. The several fractions were analyzed by GC-MS, and NMR etc. Antifungal activities were presumably showed more than 5 fractions against the pathogens. Among them, the most effective antifungal fraction was identified as 2-Methylresocinol using GC-MS, and NMR. These results suggest that the 2-Methylresocinol may be useful for biochemicals.

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Expansion of the equilibrium constants for the temperature range of 300K to 20,000K

  • Kim, Jae Gang
    • International Journal of Aeronautical and Space Sciences
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    • 제17권4호
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    • pp.455-466
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    • 2016
  • Chemical-kinetic parameters of the equilibrium constants to evaluate the reverse rate coefficients in the shock layer of a blunt body and the expanding flows are derived for the temperature range from 300 K to 20,000 K. The expanded equilibrium constants for the chemical reactions of the dissociation, ionization, associative ionization, and neutral and charge exchange reactions of the atmospheric species and carbon materials are proposed in the present work. In evaluating the equilibrium constants, the inter-nuclear potential energies of the molecular species are calculated by the analytical potential function of the Hulburt-Hirschfelder model, and the parameters of the analytical model are determined from the semi-classically calculated RKR potentials. The electronic states and energies of the atoms are calculated by the electronic energy grouping model, and the rovibrational states and energies of each electronic states of the molecules are evaluated by the WKB method. The expanded equilibrium constants for 31 types of the reactions are provided for the best curve-fit functions, and the recombination reaction rate coefficients evaluated from the present equilibrium constants are compared with existing measured values.

Effects of Water Chemistry on Aggregation and Soil Adsorption of Silver Nanoparticles

  • Bae, Sujin;Hwang, Yu Sik;Lee, Yong-Ju;Lee, Sung-Kyu
    • Environmental Analysis Health and Toxicology
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    • 제28권
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    • pp.6.1-6.7
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    • 2013
  • Objectives In this study, we investigated the influence of ionic strength and natural organic matter (NOM) on aggregation and soil adsorption of citrate-coated silver nanoparticles (AgNPs). Methods Time-resolved dynamic light scattering measurements and batch adsorption experiments were used to study their aggregation and soil adsorption behaviors, respectively. Results The aggregation rate of AgNPs increased with increasing ionic strength and decreasing NOM concentration. At higher ionic strength, the AgNPs were unstable, and thus tended to be adsorbed to the soil, while increased NOM concentration hindered soil adsorption. To understand the varying behaviors of AgNPs depending on the environmental factors, particle zeta potentials were also measured as a function of ionic strength and NOM concentration. The magnitude of particle zeta potential became more negative with decreasing ionic strength and increasing NOM concentration. These results imply that the aggregation and soil adsorption behavior of AgNPs were mainly controlled by electrical double-layer repulsion consistent with the Derjaguin-Landau-Verwey-Overbeek theory. Conclusions This study found that the aggregation and soil adsorption behavior of AgNPs are closely associated with environmental factors such as ionic strength and NOM and suggested that assessing the environmental fate and transport of nanoparticles requires a thorough understanding of particle-particle interaction mechanisms.

입자 영상 처리 시스템을 이용한 콜로이드 입자의 제타포텐셜 측정 및 나노유체 분산 특성 연구 (A Study on the Zeta Potential Measurement and the Stability Analysis of Nano Fluids using a Particle Image Processing System)

  • 이재근;김성찬;김희중;이창건;주찬홍;이래철
    • 한국분무공학회지
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    • 제8권1호
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    • pp.16-22
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    • 2003
  • Zeta potential measurements of colloid particles suspended in a liquid are performed by a Zeta Meter developed. There are many applications of colloid stability in spray technology, paints, wastewater treatment, and pharmaceuticalse. Zeta potentials of charged particles are obtained by measuring the electrophoretic velocities of the particles using video enhanced microscopy and image analysis program. The values of zeta potential of polystyrene latex(PSL), $silica(SiO_2)$M, polyvinylidence difluoride(PVDF), silicon nitride, and alumina particles in deionized (DI) water were measured to be -40.5, -31.9, -25.2, -15.1 and -10.1mV, respectively. The particles having high zeta potential less than -20 mV are stable in DI water, because the double layers of them have strong repulsive forces mutually, and the particles having low zeta potential over -20mV are unstable due to Van Der Waals forces. Silica(>20nm), PSL, aluminum and PVDF particles were found to be stable that would remain separate and well disperse, while silicon nitride and alumina particles were found to be unstable that would gradually agglomerate in DI water.

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압전적층판의 열-압전-탄성 동적 비선형 작동특성 (Thermopiezoelastic Nonlinear Dynamic Characteristics of Piezolaminated Plates)

  • 오일권
    • 한국소음진동공학회논문집
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    • 제15권7호
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    • pp.836-842
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    • 2005
  • Nonlinear dynamic characteristics of active piezolaminated plates are investigated with respect to the thermopiezoelastic behaviors. For largely deformed structures with small strain, the incremental total Lagrangian formulation is presented based on the virtual work principles. A multi-field layer-wise finite shell element is proposed for assuring high accuracy and non-linearity of displacement, electric and thermal fields. For dynamic consideration of thermopiezoelastic snap-through phenomena, the implicit Newmark's scheme with the Newton-Raphson iteration is implemented for the transient response of various piezolaminated models with symmetric or eccentric active layers. The bifurcate thermal buckling of symmetric structural models is first investigated and the characteristics of piezoelectric active responses are studied for finding snap-through piezoelectric potentials and the load-path tracking map. The thermoelastic stable and unstable postbuckling, thermopiezoelastic snap-through phenomena with several attractors are proved using the nonlinear time responses for various initial conditions and damping loss factors. Present results show that thermopiezoelastic snap-through phenomena can result in the difficulty of buckling and postbuckling control of intelligent structures.