• 제목/요약/키워드: Late effect

검색결과 1,518건 처리시간 0.029초

방사선조사가 당뇨 백서의 치주조직에 미치는 영향 (Effect of irradiation on the periodontal tissues in streptozotocin-induced diabetic rats)

  • 박동신;황의환;이상래
    • Imaging Science in Dentistry
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    • 제35권3호
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    • pp.133-139
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    • 2005
  • Purpose To observe the histopathological changes in the periodontal tissues of mandibular molars in streptozotocin-induced diabetic rats after irradiation. Materials and Methods : The male Sprague-Dawley rats weighing approximately 250 gm were divided into four groups: control, diabetes, irradiation, and diabetes- irradiation groups. Diabetes mellitus was induced in the rats by injecting streptozotocin. Rats in the control and irradiation groups were injected with citrate buffer only After 5days, the head and neck region of the rats in irradiation and diabetes-irradiation groups were irradiated with a single absorbed dose of 10Gy. All the rats were sacrificed at 3, 7, 14, 21, and 28 days after irradiation. The specimen including the mandibular molars were sectioned and observed using a histopathological method. Results In the diabetes group, osteoclastic activity was observed in the alveolar bone and the root throughout the period of experiment. Also, osteoblastic and fibroblastic activities were markedly decreased. In the irradiation group, the osteoclasts were observed in the alveolar bone and the dilated capillaries were increased in the early experimental phases. However, vigorous osteoblastic activity was noted in the late experimental phases. In the diabetes-irradiation group, osteoblastic activity in the alveolar bone and the root was observed in the early experimental phases. However, there were no resorption and osteoblastic activity in the alveolar bone and the root in the late experimental phases, and obvious atrophic change of fibrous tissues was noted. Conclusion : This experiment suggests that osteoblastic activity was caused by irradiation in the late experimental phases, but atrophic change of the periodontal ligament tissues was induced after irradiation in diabetic state.

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Effect of Indigenous Herbs on Growth, Blood Metabolites and Carcass Characteristics in the Late Fattening Period of Hanwoo Steers

  • Kim, D.H.;Kim, K.H.;Nam, I.S.;Lee, S.S.;Choi, C.W.;Kim, W.Y.;Kwon, E.G.;Lee, K.Y.;Lee, M.J.;Oh, Y.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권11호
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    • pp.1562-1568
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    • 2013
  • This study was conducted to evaluate the effects of indigenous herbal supplements on growth, blood metabolites and carcass characteristics in the late fattening period of Hanwoo steers. In a 6 month feeding trial, thirty Hanwoo steers ($647{\pm}32$ kg) were allotted to one of 5 treatment groups, control (basal diet contained lasalocid), licorice, clove, turmeric and silymarin, with six steers per pen. All groups received ad libitum concentrate and 1 kg rice straw/animal/d throughout the feeding trial. Blood samples were collected at the beginning, middle, and the end of the experiment and the steers were slaughtered at the end. Blood glucose, triglyceride, total protein, and albumin concentrations were higher in the turmeric treatment compared with other treatments. Blood urea nitrogen and creatinine concentrations were highest (p<0.003 and p = 0.071, respectively) in steers treated with silymarin. Alanine aminotransferase activity was lower (p<0.06) for licorice and silymarin compared with the control group. There were no alterations in serum aspartate aminotransferase and gamma glutamyltransferase activities as a consequence of herb treatments (p = 0.203 and 0.135, respectively). Final body weight, body weight gain, average dairy gain and dry matter intake were not significantly different among treatments. Yield grade, marbling score and quality grade were higher for silymarin group than those of the control group (p<0.05). Therefore, the results suggest that silymarin can be used an effective dietary supplement as an alternative to antibiotic feed additive and a productivity enhancer, providing safe and more consumer acceptable alternative to synthetic compounds during the late fattening period of steers.

20세기말 패션 디자인에 나타난 신표현주의적 이미지에 관한 연구

  • 이효진
    • 복식
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    • 제40권
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    • pp.5-23
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    • 1998
  • The main purpose of this study was intended to analyze the image of N대-Expressionism represented in the late of 20th century fashion design. By the late 1960s and the early 1970s. the prevailing notion of modernity, which had pushed the limits of art beyond previous boundaries, had begun to lose its urgency. Critics called the new pluralistic era which the West was entering Post-Modern. Furthermore, the predominance of America and the New York scene is diminishing, and artistic leadership is now international. Post-Modernism dialectcally made denial of Modernism as likely as New Image Painting and Decorative Pattern Painting Art in 1970's and it was availed as a dialectcal means for the pre-diction of new comings that would be appeared at painting art in 1980's. New Image Painting has been called as Neo-Expressionism. The N대-Expressionists selected human's feature because appeared flankly, directly irregular agitation in the visual effect and they believed human's destructive and amputate body was cruelty. So they express it on the surface canvas. Under the these background, the image of Neo-Expressionism was represented in the late of 20th century fashion design such as the upside-down image of human feature, the image as ameditation on German myth and history, culture, the ecletic image is made of use a mixture of material. The properties of composition, line, color, texture, and form, common to all plastic art, are now more readily recognized and historically valued in every work. That is, individuality, humanity, and the human condition have been at the core of most Western art and Fashion design. Especially Fashion design has been one of the principal instruments used to examine our nature and to promote the notion of growth, self-understanding, and change.

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수산식품의 가공 및 저장중의 조직학적 변화에 관한 연구 1. 건조에 의한 뱀장어 근육조직의 변화와 지방의 이동 (Studies on Histological Changes in Sea Foods during Processing and Storage 1. Changes in Muscular Tissue and Fat Migration of Eel, Anguilla japonica, during Drying)

  • 송대진;하진환;이응호
    • 한국수산과학회지
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    • 제15권2호
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    • pp.137-146
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    • 1982
  • 건조에 의한 뱀장어 근육조직의 변화와 지방의 이동에 대하여 조직학적인 면에서 실험한 결과를 요약하면 다음과 같다. 1. 신선한 뱀장어는 피하지방이 두터우며 진피층안에도 지방이 존재하였다. 2. 건조에 의한 근육조직의 변화는 초기단계와 말기단계로 나눌 수 있으며, 건조초기는 결체조직의 탈수가 일어나고 건조말기에는 근원섬유의 탈수가 일어난다. 3, 건조에 의한 서방의 움직임은 내부구조의 변화에 따른 근절의 벌어짐과 수축에 의하여 좌우되는 것 같으며, 건조초기보다 건조말기에 심한 것 같다. 4. 동재건조 후에는 세포내외에 수결정에 의한 흔적이 참았으며 복수 후에도 수결정의 흔적이 남았다. 5. 가열후의 조직은, 결체조직은 녹아버린 상태를 나타내고 근섬유는 탈구경화된 상태를 나타내었다.

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전방십자인대 재건술 환자의 운동프로그램 참여 시기에 따른 등척성 근기능 비교 (Comparison of the Isometric Myofunction on Anterior Cruciate Ligament Reconstruction Patients according to the Time of Participation in Exercise Program)

  • 배창환;조성현;황보각
    • 대한물리의학회지
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    • 제6권4호
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    • pp.455-464
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    • 2011
  • Purpose : This study is to investigate difference in the isometric muscular function of knee joints according to the time of participation in rehabilitation exercise in patients who had anterior cruciate ligament reconstruction. Methods : The subjects of this study were patients by sports injury or accident in the sports rehabilitation center of G hospital. The early exercise program group (n=7) started functional ability exercise from 2 weeks after the surgery and the late exercise program group (n=7) from 6 weeks after the surgery. Statistical analysis was used repeated measure ANOVA to test mean difference by using SPSS 18.0 for windows. Results : First, as to quadriceps femoris muscle according to the time of participation in exercise program, significant difference was observed according to interaction and time. Second, as to hamstring muscle according to the time of participation in exercise program, significant difference was observed in muscle strength according to time. Conclusion : This results suggest that if the effect of exercise program is similar between the early starting group and the late starting group, it is not necessary to have a long period of fixation as in the late exercise program group but is desirable to start functional ability exercise early in order to relieve pains in the knee joints.

우리나라 여성의 만혼(晩婚) 이 첫 출산간격에 미치는 영향 (Effects of the Late Marriage of Korean Women on the First-birth Interval)

  • 정우진;이경애;이선미
    • Journal of Preventive Medicine and Public Health
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    • 제39권3호
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    • pp.213-220
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    • 2006
  • Objectives: The purpose of this study was to examine the effect of women's late age of marriage on the interval between marriage and their first birth Methods: Data from Year 2000 Korea National Fertility Survey was collected through direct interview questionings, and the data was analyzed based on randomly selected sampling. In particular, the married women (N=5,648) were analyzed for the factors that determined the first-birth interval by performing Cox's proportional hazard model survival analysis. Results: Unlike previous findings, the woman whose age of marriage was 30 or more was more likely to delay the birth of her first baby than were the other women who married earlier. Further, a woman's age at marriage, a woman's residence before marriage, her husband's religion, her husband's level of education and the difference in age between the woman and her husband significantly influenced the first-birth interval. In contrast, for a married woman, her age, level of education, current residence and religion were not significant predictors of her first birth interval. Conclusions: Our study showed that women who married at the age of 30 years or more tend to postpone their first birth in Korea. When facing the increasing number of women who marry at a late age, the Korean government should implement population and social policies to encourage married women have their first child as early as possible.

Effects of High Levels of Nutrients on Growth Performance and Carcass Characteristics of Hanwoo Cattle

  • Reddy, Kondreddy Eswar;Jeong, Jin Young;Ji, Sang Yun;Baek, Youl-Chang;Lee, Seul;Kim, Minseok;Oh, Young Kyun;Lee, Hyun-Jeong
    • 한국초지조사료학회지
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    • 제38권3호
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    • pp.180-189
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    • 2018
  • The present study was conducted to evaluate the effects of high levels of nutrients on the growth performance, blood metabolites and carcass characteristics of Hanwoo cattle. Eighteen Hanwoo steers were fed two types of diets: 1) Nine animals were fed the conventional diet including typical levels of crude protein (CP) and total digestive nutrients (TDN), and 2) Nine animals were fed the treatment diet including high levels of CP and TDN. The average body weight (BW) and dry matter intake (DMI) were greater (P < 0.05) in the treatment group than in the conventional group at early and late fattening stages. Also, in the treatment group, the average daily gain (ADG) was greater (P < 0.05) at the late fattening stage. The serum total lipid and cholesterol levels were higher (P < 0.05) in the late fattening stage of treatment group. The carcass weight, total fat weight, longissimus muscle area and the grade of meat quality were also greater (P < 0.05) in the treatment group than the conventional diet group. This study demonstrates that high levels of CP and TDN exhibit a positive effect on the growth performance and carcass characteristics, indicating that high levels of CP and TDN can be used as a cost-effective feeding program for Hanwoo cattle by shortening the feeding period.

Cognitive Ability in Midlife and Labor Market Participation Among Older Workers: Prospective Cohort Study With Register Follow-up

  • Sundstrup, Emil;Hansen, Ase M.;Mortensen, Erik L.;Poulsen, Otto M.;Clausen, Thomas;Rugulies, Reiner;Moller, Anne;Andersen, Lars L.
    • Safety and Health at Work
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    • 제11권3호
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    • pp.291-300
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    • 2020
  • Background: The study aimed to determine the association of individual cognitive ability in late midlife with labor market participation among older workers. Methods: This prospective cohort study estimates the risk of long-term sickness absence, disability pension, early retirement, and unemployment from scores on the Intelligenz-Struktur-Test 2000R by combining data from 5076 workers from the Copenhagen Aging and Midlife Biobank with a register on social transfer payments. Analyses were stepwise adjusted for age, gender, physical and psychosocial work environment, health behaviors, occupational social class, education, and chronic diseases. Results: In the fully adjusted model, low cognitive ability (≥1 standard deviation below the mean for each gender) and high cognitive ability (≥1 standard deviation above the mean for each gender) were not associated with risk of any of the four labor market outcomes. Conclusion: Individual cognitive ability in late midlife was not associated with risk of long-term sickness absence, disability pension, early retirement, and unemployment in the fully adjusted model. Thus, no direct effect of individual cognitive ability in late midlife was observed on the risk of permanently or temporarily leaving the labor market.

Treatment Outcome for Head and Neck Squamous Cell Carcinoma in a Developing Country: University Malaya Medical Centre, Malaysia from 2003-2010

  • Wong, Yoke Fui;Yusof, Mastura Md;Ishak, Wan Zamaniah Wan;Alip, Adlinda;Phua, Vincent Chee Ee
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권7호
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    • pp.2903-2908
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    • 2015
  • Background: Head and neck cancer (HNC) is the eighth most common cancer as estimated from worldwide data. The incidence of HNC in Peninsular Malaysia was reported as 8.5 per 100,000 population. This study was aimed to determine the treatment outcomes for HNC patients treated in the Oncology Unit of University Malaya Medical Centre (UMMC). Materials and Methods: All newly diagnosed patients with squamous cell carcinoma of head and neck (HNSCC) referred for treatment to the Oncology Unit at UMMC from 2003-2010 were retrospectively analyzed. Treatment outcomes were 5-year overall survival (OS), cause specific survival (CSS), loco-regional control (LRC) and radiotherapy (RT) related side effects. Kaplan-Meier and log rank analyses were used to determine survival outcomes, stratified according to American Joint Committee on Cancer (AJCC) stage. Results: A total of 130 cases were analysed. Most cases (81.5%) were at late stage (AJCC III-IVB) at presentation. The 5-year OS for the whole study population was 34.4% with a median follow up of 24 months. The 5-year OS according to AJCC stage was 100%, 48.2%, 41.4% and 22.0% for stage I, II, III and IVA-B, respectively. The 5-year overall CSS and LCR were 45.4% and 55.4%, respectively. Late effects of RT were documented in 41.4% of patients. The most common late effect was xerostomia. Conclusions: The treatment outcome of HNSCC at our centre is lagging behind those of developed nations. Efforts to increase the number of patients presenting in earlier stages, increase in the use of combined modality treatment, especially concurrent chemoradiotherapy and implementation of intensity modulated radiotherapy, may lead to better outcomes for our HNC patients.

친환경적 밤 종실해충 방제 연구 (Study on Chestnut Insect Pests by Environmentally Friendly Controls in Korea)

  • 이총규
    • 한국응용곤충학회지
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    • 제48권1호
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    • pp.95-100
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    • 2009
  • 밤 종실의 생산량과 재배 농가의 소득증대를 위한 친환경적 방제 기술을 보급하고자 밤의 주 생산지인 경상남도 밤나무 집단 재배지에서 몇 가지 친환경적인 방법으로 처리하였다. 그 결과, 복숭아명나방(Dichocrocis punctiferalis)의 피해율은 조생종(단택, 삼조생)의 경우, 웜스톱 처리구에서 피해율이 7.76%로 가장 낮았고, 웜스톱+목초액, 포충등 처리구 순으로 증가였다. 중생종(유마, 축파)의 피해율은 웜스톰 처리구에서 13.39%로 가장 낮았으며, 만생종(박미, 은기)은 피해율간 유의차가 있었다(p<0.05). 처리별 방제가는 조생종, 만생종 밤의 웜스톱 처리구에서 각각 40.49%, 41.89%로 가장 높았다. 밤바구미(Curculio sikkimensis)의 피해율은 조생종과 중생종 밤에서 낮았으며, 숙기별 처리간의 유의차가 없었다(p>0.05). 만생종 밤에서의 피해율은 웜스톱과 이미다클로프리드 처리구가 15.38%로 가장 피해율이 낮았으며, 항공방제, 웜스톱, 포충등 처리구 순이었다. 밤바구미(Curculio sikkimensis)에 대한 처리별 방제가는 조생종과 중생종에서는 낮았고, 만생종의 웜스톱과 이미다클로프리드, 항공방제 처리구에서 방제가는 각각 34.59%, 28.94%였다.