• Journal of Chest Surgery
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• 제24권7호
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• pp.693-700
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• 1991

A rare case of the association of distal aortopulmonary septal defect, aortic origin of the right pulmonary artery, intact ventricular septum, patent ductus arteriosus and interrupted aortic isthmus in a 40-day-old infant is reported. The infant was suffered from two operations with an interval of nine days. At the first operation a 10mm polytetrafluoroethylene prosthesis was inserted instead of the interrupted aortic isthmus and ductus was ligated via the left posterolateral thoracotomy. But the patient could not be weaned from the respirator because of large amount of left-to-right shunt. So the total correction was subsequently performed after an interval of nine days. At the second operation, tunneling of the right pulmonary artery to the main pulmonary artery through the aortopulmonary septal defect was performed using the Dacron patch via a longitudinal transaortic approach and a separate autologous pericardial patch was applied to the longitudinally incised margins of the anterior wall of the ascending aorta. The second postoperative course was relatively uneventful except some respiratory distress and nutritional problems. Now he is at 6 months of age and thrives well without any symptom. Because the success of the surgical repair of this complex anomalies depends upon the accurate diagnosis and meticulous design of each step of procedure prior to operation these problems are also discussed.

• 한국조경학회지
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• 제35권5호
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• pp.56-63
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• 2007

This study used the nearest feature model to connect forest patches within the western Geum River Basin. Due to many different forest patch sizes, 3 alternative methods were tested to determine the best way to establish an ecological network with forest patches. Alternative 1 used all forest patches to determine whether patches were large enough. Alternative 2 used forest patches over 10 ha in size. Alternative 3 used natural conservation indices to select forest patches containing better qualities in the natural conservation level. As a result 635 out of 724 patches of over 10 ha were selected for comparison. Alternative 1 showed that forest patches of less than 10 ha were outliers interrupting the establishment of the ecological network. They generated an unnecessary ecological network to link core areas to comparison features. The ecological network was improved by using forest patches greater than 10 ha in size(Alternative 2). Each comparison feature was much more hierarchically connected to core areas in Alternative 2 than in Alternative 1. Forest patches filtered by natural conservation indices were useful for obtaining the best ecological network. Alternative 3 clearly showed the connections in the ecological network between core areas and forest.

• 한국통신학회논문지
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• 제29권4C호
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• pp.472-484
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• 2004

본 논문에서는 CEGI (Complex Extended Gaussian Image)를 이용한 3D 메쉬 모델 워터마킹 알고리즘을 제안하였다. 제안한 알고리즘에서는 VRML 데이터의 3D 메쉬 모델을 6개 패치로 분할한 후, 각 패치의 CEGI 분포에서 복소 가중치의 크기가 큰 셀에 투영되는 메쉬의 법선 백터 방향에 워터마크를 삽입한다. 그리고 각 패치의 중점 좌표 및 CEGI 크기 분포의 우선 순위 정보를 이용하여 워터마크를 추출한다. 또한 아편 (affine) 변형된 모델에서는 패치의 초기 중점 좌표의 재배열 과정을 이용하여 원 모델의 방향으로 전환한 후, 워터마크를 추출한다. 본 논문에서 제안한 알고리즘의 성능을 평가하기 위한 실험에서 기하학적 및 위상학적 변형에 강인한 특성을 가짐을 확인하였다.

• 한국전자파학회논문지
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• 제15권1호
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• pp.60-67
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• 2004

본 논문에서는 디세그멘테이션 기법을 이용하여 사각 링 패치 안테나를 해석하였으며, 그린함수로부터의 직사각형 세그먼트의 임피던스 계산과 평면 전자기 구조체에 대한 디세그멘테이션 방법이 논의되고 있다. 사각 링 캐버티는 큰 사각형 캐버티에서 작은 사각형 캐버티를 빼낸 구조이므로, 사각형 캐버티에 대한 그린함수의 항으로 표현된 각각의 임피던스 행렬들에 다 단자 결합법을 적용하여 사각 링 캐버티의 전체 임피던스 매트릭스를 구한다. 전자계는 8개 경계조건을 만족하는 벡터 포텐셜로부터 구할 수 있다. 각 에지에서의 전자계 분포는 여기된 모드에 따라 막대 그래프로 표현하였다. 이 결과를 이용하여 사각 링 패치 안테나의 동작모드를 분석할 수 있다.

• 대한의생명과학회지
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• 제18권3호
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• pp.218-226
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• 2012

Dopamine is an enteric neurotransmitter that regulates gastrointestinal motility. This study was done to investigate whether dopamine modulates spontaneous pacemaker activity in cultured interstitial cells of Cajal (ICCs) from mouse using whole cell patch clamp technique, RT-PCR and live $Ca^{2+}$ imaging analysis. ICCs generate pacemaker inward currents at a holding potential of -70 mV and generate pacemaker potentials in current-clamp mode. Dopamine did not change the frequency and amplitude of pacemaker activity in small intestinal ICCs. On the contrary dopamine reduced the frequency and amplitude of pacemaker activity in large intestinal ICCs. RT-PCR analysis revealed that Dopamine2 and 4-receptors are expressed in c-Kit positive ICCs. Dopamine2 and 4 receptor agonists inhibited pacemaker activity in large intestinal ICCs mimicked those of dopamine. Domperidone, dopamine2 receptor antagonist, increased the frequency of pacemaker activity of large intestinal ICCs. In $Ca^{2+}$-imaging, dopamine inhibited spontaneous intracellular $Ca^{2+}$ oscillations of ICCs. These results suggest that dopamine can regulate gastrointestinal motility through modulating pacemaker activity of large intestinal ICCs and dopamine effects on ICCs are mediated by dopamine2 receptor and intracellular $Ca^{2+}$ modulation.

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5359-5364
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• 2015

Background: Multiple complex pathways are operable in the evolution of cutaneous T cell lymphomas (CTCLs). These pathways involve interaction between neoplastic T cells and cells of the immune system (especially dendritic cells and the non-malignant T cells). Granulysin is a proinflammatory antimicrobial peptide which has an immune alarmin function, activating dendritic cells, as well as an active role in tumor immunology and prognosis. FOXP3+ regulatory T cells Tregs are an important player in the immune system. Much controversy is found in the literature about the role of Tregs in CTCL. Aim: The present study aimed to investigate the expression of granulysin and FOXP3 in mycosis fungoides (MF), its precursor lesion large plaque parapsoriasis and its leukemic form ;$s\acute{e}ezary$ syndrome (SS). Materials and Methods: Immunohistochemical expression of granulysin and FOXP3 were assessed in lesional skin biopsies taken from 58 patients (4 large plaque parapsoriasis, 48 MF and 6 SS). Results: Granulysin positivity was cytoplasmic and higher in MF than in parapsoriasis en plaque and higher in the more advanced stages of MF (p<0.001). All groups showed significant differences between each other except between MF tumor stage and SS. FOXP3 positivity was nuclear and higher in early stage MF (plaque and patch stages) than in tumor stages and SS (p<0.001). However the FOXP3 count was lower in parapsoriasis en plaque than in other stages of MF. All the groups showed significant differences between each other except between parapsoriasis and SS and between patch and plaque stages of MF. Conclusions: The present study supports a role for granulysin in MF progression and proposes a novel hypothesis about the effect of FOXP3 +veTregs in the suppression of the activity of the neoplastic cells in MF.

• 해양환경안전학회지
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• 제21권5호
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• pp.543-551
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• 2015

본 논문에서는 교량, 선박 등에 사용하고 해양환경을 고려한 알루미늄 합금(A6082-T-6) 플레이트 거더의 물리적 관계를 살펴보고자 한다. 플레이트 거더는 제품수명주기에 이동하중, 적재하중 등 같은 패치로딩을 경험하게 된다. 이 하중을 받는 알루미늄합금 플레이트 거더의 최종강도에 대해 다수 수치모형을 적용하여 탄소성 대변형 시리즈 해석을 수행하고 회귀분석을 통해 예측식을 제안하였다. 예측식은 최종강도와 세장변수의 상관관계로 나타냈으며 세장변수가 낮을 경우(0-2.3) 약 9 % 정도 오차가 발생하며 높을 경우(2.3-4.0) 약 1-2 % 정도 오차가 발생하였다. 따라서 제안 예측식 적정성은 합리적으로 평가할 수 있는 것으로 확인되었다.

• 한국환경복원기술학회지
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• 제19권3호
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• pp.29-44
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• 2016

The purpose of this study is to quantitatively and visually analyze the degree of green biotope fragmentation caused by road construction and other development work using FRAGSTATS and GUIDOS tool. Moreover, linking of the endangered species research, we mapped "Biotope Fragmentation Map" of Daejeon-city. The findings of the study are summarized as follows: First, as the result of FRAGSTATS, landscape indices : number of patch(NP), mean patch size (MPS), edge length(TE), mean nearest neighbor distance(MNN), edge shape(LSI) showed meaningful change from fragmentation. Moreover, the result of GUIDOS analysis, middle core-small core-bridge-branch-edge-islet-perforation showed increase of area percentage without large core. Lastly, analysis result of 'Biotope Fragmentation Map' revealed that changing site of large core's size appeared eighteen-site and designated as the special protection area appeared forty-one site. As the result of the two data, overlapping areas that showed both change of core size and revealed special protection areas revealed four site. For example, five species of endangered species appeared on the NO. 4 site in 'Biotope Fragmentation Map'. The findings of this study as summarized above are considered to play an important role in basic data preventing green biotope fragmentation at the planned level from various development work.

• 한국산학기술학회논문지
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• 제19권11호
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• pp.31-37
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• 2018

본 논문에서는 효과적이고 저 복잡도를 갖는 단일 영상 기반의 안개 제거를 위하여 dual dark channel prior (DCP)와 적응적인 밝기 보정 기법을 이용하는 알고리즘을 제안한다. 작은 크기의 패치에 의한 dark channel은 영상의 에지 정보를 잘 보존하지만 국부적인 잡음 및 밝기 변화에 민감한 반면, 큰 크기의 패치에 의한 dark channel은 정확한 안개 값을 추정하는데 유리하지만 블록 현상과 이로 인한 후광 효과는 안개 제거 성능을 떨어뜨린다. 이러한 문제를 해결하기 위하여 기존의 방법에서는 계산량 및 메모리 요구량이 큰 matting 기법을 활용한 반면, 제안하는 방법은 크기가 다른 패치로부터 구한 dark channel을 합성하여 dual DCP를 구성하고, 이를 이용하여 안개를 제거함으로써 적은 계산량 및 메모리 요구량을 달성한다. 또한 안개 성분을 제거한 영상에 적응적 밝기 보정 기법을 적용하여 영상에 포함된 객체가 선명하게 보존될 수 있도록 한다. 안개 성분이 포함된 다양한 영상에 대해 수행한 실험 결과 제안하는 안개 제거 기법이 기존의 방법에 비해 안개 제거 성능이 우수하면서 계산량과 메모리 요구량이 감소함을 알 수 있다.

• Journal of Chest Surgery
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• 제11권2호
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• pp.175-180
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• 1978

A rare form of tetralogy of Fallot, in which large ventricular septal defect was located at subpulmonary position rather than beneath a well developed crista supraventricularis was operated in this Department. This case satisfied the criteria for the diagnosis of tetralogy of Fallot, having large ventricular septal defect beneath the aortic valve with overriding of aorta, pulmonary stenosis and right ventricular hypeFtrophy. The operation was done through a median sternotomy using cardiopulmonary bypass. A vertical right ventriculotomy was extended to the pulmonary valve ring. Pulmonary and aortic valve were adjacent to each other, in contrast to the situation of classic tetralogy of Fallot. Pulmonary valvulotomy was done and ventricular septal defect was closed. with Teflon, and right ventricular outflow tract was reconstructed with woven Dacron covered by pericardial patch after minimal resection of septal band. The post-operatiove courses was uneventful except wound infection. The patient was discharged 15 days after open heart surgery.