• 대한한의학원전학회지
• /
• 제22권3호
• /
• pp.107-131
• /
• 2009

After having comparison, the Bunchon-ga in nine books -"Chimguchwiyeong(鍼灸聚英)", "Nengmunjeonsudong-injihyeol(凌門傳授銅人指穴)", "Chimgumundae(針灸問對)", "Gyeongrakgo(經絡考)", "Gyeongrakhoepyeon(經絡匯編)", "Geumchimbijeon(金針秘傳)", "Jagusimbeop-yogyeol(刺灸心法要訣)", "Chimgubongwon(鍼灸逢源)" "Chimgusinseo(鍼灸神書)", and invested the difference based on "Chimguhak(鍼灸學)", "WHO standard acupuncture point location" I got some conclusion like below. Two kinds of Bunchon-ga are similar in "Chimguchwiyeong", "Nengmunjeonsudong-injihyeol", and also in "Gyeongrakgo(經絡考)", "Gyeongrakhoepyeon(經絡匯編)", and "Geumchimbijeon(金針秘傳)" Bunchon-ga of twelve meridian is different from their order - Stomach meridian(胃經), Bladder meridian(膀胱經), Kidney meridian(腎經), Triple Energizer meridian(三焦經), and Gallbladder meridian(膽經). In nine kinds of Bunchon-ga, missing acupuncture points(漏落穴) are generally located on the first line of Bladder meridian(膀胱經) - from Daejeo(大杼) to Baekhwansu(白環兪), and Pungsi(風市), Haegye(解谿), Yangsi(羊矢), Geummaek(急脈) are not appeared in them, Hyeopdang(脇堂), Michung(眉衝), Yanghyeol(陽穴) are recorded. There are some parts adapted different way of proportional bone chon - from Yanggok(陽谿) to Gokji(曲池) in Large Intestine meridian[大腸經], from Sanggu(商丘) to Umreungcheon(陰陵泉) in Spleen meridian[脾經], and from Oegwan(外關) to Sadok(四瀆) in Triple Energizer meridian[三焦經]. The acupuncture points explained by structure, there are many different finger chons between some books. Bunchon on breast and abdomen, is generally explained by vertical, horizontal finger chon based on Governor vessel[任脈], vertical explanations of each book have little difference opinions, but horizontal have many. Especially, the locations of Eunmum(殷門), Bukeuk(浮郄) and Wiyang(委陽) are extremely different from "Chimguhak(鍼灸學)", and "WHO standard acupuncture point locations".

• 한국환경복원기술학회지
• /
• 제16권5호
• /
• pp.83-92
• /
• 2013

The present study documented the characteristics of habitats and nests of Goshawk [Northern goshawk] Accipiter gentilis breeding in Gongju-si, Chungcheongnam-do and Haepyung, Kyungsangbuk-do, Eumsung-gun, Chungju-si, Chungcheongbuk-do from April 2007 to August 2011. Breeding habitat includes of mixes and deciduous trees and ravine forest, ranging from small to large areas and it used make a new nest and fix up the old nest at Goshawk. Goshawk make nests on Japanese larch Larix leptolepis, Japanese red pine Pinus densiflora and Pitch pine Pinus rigidae of $15.8{\pm}2.36m$ (range=7.4~18.7m) in height and $34.6{\pm}7.38cm$ (range=20.8~47.4cm) in diameter-at-breast height (DBH). It has $135.8{\pm}3.37cm$ in outer diameter of nest, $26.2{\pm}2.39cm$ in inner diameter, $7.1{\pm}1.41cm$ of depth, and $3.1{\pm}0.40Kg$ of weight. Breeding habitat (n=13) has 5~7 nests. It has 7 (53.8%) nest in fix up the old nest and 4 (30.8%)nests in make a new nest.

• 한국생물물리학회:학술대회논문집
• /
• 한국생물물리학회 2003년도 정기총회 및 학술발표회
• /
• pp.69-69
• /
• 2003

Human CD99 is a ubiquitous 32-kDa transmembrane protein encoded by the mic2 gene. The major cellular functions of CD99 protein are related to homotypic cell adhension, apoptosis, vesicular protein transport, and differentiation of thymocytes or T cells. Recently it has been reported that expression of a splice variant of CD99 transmembrane protein (Type I and Type II) increases invasive ability of human breast cancer cells. To understand structural basis for cellular functions of CD99 (Type I), we have initiated studies on hCD99$^{TMcytoI}$ and hCD99$^{cytoI}$ using circular dichroism (CD) and multi-dimensional NMR spectroscopy. CD spectrum of hCD99$^{TMcytoI}$ in the presence of 200mM DPC and CHAPS displayed an existence $\alpha$-helical conformation. The solution structure of hCD99$^{cytoI}$ determined by NMR is composed of one N-terminal $\alpha$-helix, $\alpha$A, two C-terminal short $\alpha$-helix segments, $\alpha$B and $\alpha$C. While $\alpha$A and $\alpha$B are connected by the long flexible loop, $\alpha$B and $\alpha$C connected by type III$\beta$-turn. Although it has been rarely figured out the correlation between structure and functional mechanism of hCD99$^{TMcytoI}$ and hCD99$^{cytoI}$, there is possibility of dimerization or oligomerization. In addition, the feasible mechanism of hCD99$^{cytoI}$ is that it could have intramolecular interaction between the N- and C- terminal domain through large flexible AB loop.

• 산업경영시스템학회지
• /
• 제41권2호
• /
• pp.1-8
• /
• 2018

K-means algorithm is one of the most popular and widely used clustering method because it is easy to implement and very efficient. However, this method has the limitation to be used with fixed number of clusters because of only considering the intra-cluster distance to evaluate the data clustering solutions. Silhouette is useful and stable valid index to decide the data clustering solution with number of clusters to consider the intra and inter cluster distance for unsupervised data. However, this valid index has high computational burden because of considering quality measure for each data object. The objective of this paper is to propose the fast and simple speed-up method to overcome this limitation to use silhouette for the effective large-scale data clustering. In the first step, the proposed method calculates and saves the distance for each data once. In the second step, this distance matrix is used to calculate the relative distance rate ($V_j$) of each data j and this rate is used to choose the suitable number of clusters without much computation time. In the third step, the proposed efficient heuristic algorithm (Group search optimization, GSO, in this paper) can search the global optimum with saving computational capacity with good initial solutions using $V_j$ probabilistically for the data clustering. The performance of our proposed method is validated to save significantly computation time against the original silhouette only using Ruspini, Iris, Wine and Breast cancer in UCI machine learning repository datasets by experiment and analysis. Especially, the performance of our proposed method is much better than previous method for the larger size of data.

• 대한기관식도과학회지
• /
• 제6권1호
• /
• pp.102-107
• /
• 2000

Monocytoid B-cell lymphoma is uncommon, low grade lymphoma originating from monocytoid B lymphocytes. Monocytoid B-cell lymphoma usually presents as a localized lymphadenopathy. Peripheral lymph nodes are most often involved, particularly those in the frequent in the head and neck area. A distinctive feature is the association of monocytoid B-cell lymphoma with autoimmune diseases. Sjogren Syndrome had been present in 22% of patient with monocytoid lymphoma. Extranodal involvement by monocytoid lymphoma was reported in the salivary gland, breast, thyroid, and stomach. There were also occasional extensions to the liver and retroperitoneum. The bone marrow and peripheral blood involvement by monocytoid lymphoma is very rare, which is frequently seen in hairly cell leukemia. Fever, weight loss, and other constitutional signs are usually absent. Most patients have no symptoms, and the only sign is enlarged lymph nodes. The clinical course remains indolent; most patients are in complete remission and recurrence with progression to a high-grade lymphoma of large cell type was recorded only in a few cases. Authors experienced a case of monocytoid B-cell lymphoma associated with Sjogren Syndrome mistaken to simple cervical lymphadenitis in a 60-year-old female. We report this case with a review of literatures.

• Journal of Korean Medical Science
• /
• 제33권44호
• /
• pp.273.1-273.15
• /
• 2018

Background: Sparganosis is a larval cestodiasis caused by the plerocercoid of Spirometra spp. Since the first description of human sparganosis in 1924, several hundred cases have been reported in Korea. However, systematic approaches for literature surveys of Korean sparganosis have seldom appeared. Methods: We searched publicly available databases such as PubMed, Research Information Sharing Service, and Korea Medical Citation Index with relevant Medical Subject Headings. Results: At least 438 Korean sparganosis cases have been described from 1924 to 2015. Preoperative diagnosis has been significantly increased since the 1980s due to popularization of serological and imaging diagnostics. Cases were largely detected from fifth decades in general, but cerebral sparganosis was detected in relatively young age groups (third and fourth decades). Sparganosis was prevalent in men (75.9%). Consumption of frog/snake and drinking unfiltered water were found in 63.4% and 16.9% of patients, respectively. Most frequently affected sites were subcutaneous tissues (49.9%), followed by the central nervous system (36.2%). Involvements of visceral organs (7.6%), ocular regions (3.6%), and muscles (2.7%) were noticed. In women, breast sparganosis constituted a large proportion (34.2%). Sparganosis associated with immunocompromised patients has recently been reported. Conclusion: Sparganosis has been continuously reported in Korea during the past 90 years, although its incidence has decreased during the last 20 years. The disease is mostly characterized by subcutaneous nodule, but infection of the worm in vital organs often results in serious illness. Continuous awareness is warranted to monitor sparganosis occurrence and associated clinical consequences.

• 농업생명과학연구
• /
• 제52권6호
• /
• pp.37-47
• /
• 2018

본 연구의 목적은 전국에 분포하는 일본잎갈나무 임분에 대해 산림시업 수행이 직경분포변화에 미치는 영향에 대해 분석하였다. 본 연구에 사용한 자료는 국가산림자원조사 중 시업지 232plots, 비시업지 47plots의 고정표본점 자료를 활용하였다. 직경분포모델은 Weibull 누적분포함수를 사용하였으며, 분석 방법에는 백분위(Percentile)에 근거한 직경모형추정, 백분위(Percentile)에 대한 모수복구 방법을 사용하였다. 개발한 모델을 이용하여 산림시업의 수행여부에 따른 시나리오(임령, 지위지수, 임분밀도) 별임분생장량을 예측한 결과, 시업지 임분의 최대임목본수를 차지하는 평균 흉고직경의 이동이 비시업지 임분에 비해 이동량과 생장량이 더 높게 나타났으며, 대경목이 차지하는 비율 또한 시업지 임분이 높게 예측되었다. 본 연구의 결과는 직경급에 따른 목재생산량의 장기적인 예측과 동적인 임분구조 해석에 기초적인 정보를 제공할 수 있을 것으로 사료되어진다.

• Advances in nano research
• /
• 제7권4호
• /
• pp.241-248
• /
• 2019

Recent researches demonstrated well promising anticancer activities for antibiotics. Such effects would be significantly increased while nanoparticle based delivery systems were applied. In this study, the goal was aim to improve anticancer and antitoxic effects of Streptomycin by loading on special kind of dendrimer (anionic-linear-globular second generation). In the current study, Size and zeta potential as well as AFM techniques have been used to prove the fact that the loading was performed correctly. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the drug loaded on dendrimer nanoparticle were determined and compared with both of dendrimer alone and free drug with respect to staphylococcus aureus as the test microorganism. The anticancer activity among three groups including Streptomycin, Streptomycin -G2 dendrimer, and control was measured in vitro. In vitro studies showed that G2 anionic linear-globular polyethylene-glycol-based dendrimer, which loaded on Streptomycin was able to significantly improve the treatment efficacy over clinical Streptomycin alone with respect to proliferation assay. Maximal inhibitory concentration (IC50) was calculated to be $257{\mu}g/mL$ for streptomycin alone and $55{\mu}g/mL$ for Streptomycin -G2 dendrimer. In addition, Streptomycin -G2 dendrimer conjugate prevented the growth of MCF-7 cancerous cells in addition to enhance the number of apoptotic and necrotic cells as demonstrated by an annexin V-fluorescein isothiocyanate assay. Streptomycin -G2 dendrimer conjugate was able to increase Bcl-2/Bax ratio in a large scale compared with the control group and Streptomycin alone. Based on results a new drug formulation based nano-particulate was improved against S. aureus with sustained release and enhanced antibacterial activity as well as anticancer activity shown for functional cancer treatment with low side effects.

• Journal of Forest and Environmental Science
• /
• 제37권3호
• /
• pp.169-192
• /
• 2021

Sacred groves are large areas of virgin or human-modified landscape with a diverse range of species that have been protected by local people for centuries due to cultural, religious beliefs, and taboo that the deities live in them and protect the villagers from various calamities. The present study was carried out for quantitative analysis of diversity, population structure, regeneration and conservation status of tree species in the four 36.86 ha sacred groves of Jhargram district in West Bengal. Tree species composition, population structure and regeneration status were analyzed by randomly establishing of 1 ha subplots within the sacred groves. Density, frequency, basal area, abundance, evenness, and other diversity indices were calculated for adult trees with girth at breast height (GBH) >31 cm. A total of 146 tree species belonging to 116 genera distributed in 44 families from 21 orders were recorded. Pterospermum suberifolium, family Malvaceae showed the highest Species Importance Value Index (SIVI, 21.33) and Fabaceae showed the highest Family Importance Value Index (FIVI, 35.59) values respectively. Individuals are categorised into three groups, seedling, sapling and adult based on girth classes. The majority of tree species exhibited good (52.74%) regeneration followed by fairly (24.66%), poor (15.75%) and no regeneration (6.85%) respectively. With the healthy existence of the sacred grove, the overall population structure of tree species showed a strong regeneration potential. The current data will be useful in determining the current status of tree species and will be used by the forest department, politicians, and conservationists to establish management plans for the conservation of priority species in the region. Since the study areas were sacred groves, tribal members were keen to preserve them due to their religious significance.

• Journal of Ecology and Environment
• /
• 제46권1호
• /
• pp.85-98
• /
• 2022

Background: Korean white pine (Pinus koraiensis) is a major commercial species, and the importance of the oak trees (Quercus spp.) is increasing due to various factors such as environmental and ecological values. However, more information is required to clearly understand the growth characteristics of these species especially regarding thinning intensity. This study was performed to provide the basic information to develop the silvicultural guideline and field manual by analyzing tree and stand characteristics in line with thinning intensity in the Korean white pine plantation and oak-dominated natural deciduous forest. Results: Diameter at breast height (DBH) and volume changes by the thinning intensity in the Korean white pine plantation were significantly different from those in the oak-dominated deciduous natural forest. In particular, DBH distribution in the pine stand appeared that there were more large diameter trees as the thinning intensity was higher. DBH periodic annual increment (PAI) of the pine stand was higher as the thinning intensity was stronger and the growth period was shorter. This trend was similarly shown in the natural deciduous forest, but the amount of PAI was smaller than in pine stand. The volume PAI after thinning was not decreased over time. In each stand type, the PAI tended to be lower as stand density was higher. The volume PAI in the pine stand was significantly higher than that in the oak-dominated natural deciduous forest. Dead trees occurred the most in the unthinned plots of each stand type, and those were higher in the natural deciduous forest. Ingrowth trees were observed only in the natural deciduous forest, and its distribution was the lowest in unthinned plots; Korean white pine as ingrowth occurred the most frequently among many tree species. Conclusions: Different effects of thinning treatment on DBH and volume PAI, mortality, and ingrowth were observed for each stand. With respect to forest growth, Korean white pine plantation was superior to the oak-dominated natural deciduous forest. The results of this study offer fundamental information for the development of silvicultural guidelines for Korean white pine plantations and oak-dominated natural deciduous forests in Korea.