• Title/Summary/Keyword: Large Amplitude

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Compensation of the Error Rate for the Non-invasive Sphygmomanometer System Using a Tactile Sensor

  • Jeong, In-Cheol;Choi, Yoo-Nah;Yoon, Hyung-Ro
    • Journal of Electrical Engineering and Technology
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    • 제2권1호
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    • pp.136-141
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    • 2007
  • The Purpose Of This Paper Is To Use A Tactile Sensor To Compensate The Error Rate. Most Automated Sphygmomanometers Use The Oscillometric Method And Characteristic Ratio To Estimate Systolic And Diastolic Blood Pressure. However, Based On The Fact That Maximum Amplitude Of The Oscillometric Waveform And Characteristic Ratio Are Affected By Compliance Of The Aorta And Large Arteries, A Method To Measure The Artery Stiffness By Using A Tactile Sensor Was Chosen In Order To Integrate It With The Sphygmomanometer In The Future Instead Of Using Photoplethysmography. Since Tactile Sensors Have Very Weak Movements, Efforts Were Made To Maintain The Subject's Arm In A Fixed Position, And A 40hz Low Pass Filter Was Used To Eliminate Noise From The Power Source As Well As High Frequency Noise. An Analyzing Program Was Made To Get Time Delay Between The First And Second Peak Of The Averaged Digital Volume Pulse(${\Delta}t_{dvp}$), And The Subject's Height Was Divided By ${\Delta}t_{dvp}$ To Calculate The Stiffness Index Of The Arteries($Si_{dvp}$). Regression Equations Of Systolic And Diastolic Pressure Using $Si_{dvp}$ And Mean Arterial Pressure(Map) Were Computed From The Test Group (60 Subjects) Among A Total Of 121 Subjects(Age: $44.9{\pm}16.5$, Male: Female=40:81) And Were Tested In 61 Subjects To Compensate The Error Rate. Error Rates Considering All Subjects Were Systolic $4.62{\pm}9.39mmhg$, And Diastolic $14.40{\pm}9.62mmhg$, And Those In The Test Set Were $3.48{\pm}9.32mmhg,\;And\;14.34{\pm}9.67mmhg$ Each. Consequently, Error Rates Were Compensated Especially In Diastolic Pressure Using $Si_{dvp}$, Various Slopes From Digital Volume Pulse And Map To Systolic-$1.91{\pm}7.57mmhg$ And Diastolic $0.05{\pm}7.49mmhg$.

곰소만 지역의 기반암 및 상부 층서 파악을 위한 시험 탄성파반사법 탐사 (A Short Seismic Reflection Survey for Delineating the Basement and the Upper Units of the Gomso Bay, Yellow Sea)

  • 김지수;양우헌;한수형;김학수
    • 지질공학
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    • 제16권2호
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    • pp.161-169
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    • 2006
  • 곰소만의 기반암과 상부 층서들을 규명하기 위해 짧은 측선의 탄성파 반사법탐사가 수행되었다. 이 연구는 주로 자료 처리에서 신호대잡음을 높임으로써 기반암을 규명하는데 초점을 두었다. 자료처리의 주요과정은 종합 전후과정에서 모두 큰 진폭의 잡음에 가려진 신호성분을 향상시키는데 중점을 두었으며 시변필터, 불량 트레이스 제거, f-k 필터와 NMO 보정 후의 뮤팅 등이 이에 포함된다. 이 연구에서 규명된 기반암과 상부 층서들은 이전에 수행된 MT자료의 결과와 대체로 일치하며 당시에 자료질의 한계로 규명되지 못한 측선 중앙부근에서 기반암 표면이 약 30m 깊이의 수평층으로 나타났다.

Effects of Pharmacological Modulators of $Ca^{2+}-activated\;K^+$ Channels on Proliferation of Human Dermal Fibroblast

  • Yun, Ji-Hyun;Kim, Tae-Ho;Myung, Soon-Chul;Bang, Hyo-Weon;Lim, In-Ja
    • The Korean Journal of Physiology and Pharmacology
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    • 제10권2호
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    • pp.95-99
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    • 2006
  • Employing electrophysiological and cell proliferation assay techniques, we studied the effects of $Ca^{2+}$ -activated $K^+$ channel modulators on the proliferation of human dermal fibroblasts, which is important in wound healing. Macroscopic voltage-dependent outward $K^+$ currents were found at about -40 mV stepped from a holding potential of -70 mV. The amplitude of $K^+$ current was increased by NS1619, a specific large-conductance $Ca^{2+}$-activated $K^+$ (BK) channel activator, but decreased by iberiotoxin (IBTX), a specific BK channel inhibitor. To investigate the presence of an intermediate-conductance $Ca^{2+}$-activated $K^+$ (IK) channels, we pretreated the fibroblasts with low dose of TEA to block BK currents, and added 1-EBIO (an IK activator). 1-EBIO recovered the currents inhibited by TEA. When various $Ca^{2+}$-activated $K^+$ channel modulators were added into culture media for 1∼3 days, NS1619 or 1-EBIO inhibited the cell proliferation. On the other hand, IBTX, clotrimazole or apamin, a small conductance $Ca^{2+}$-activated $K^+$ channel (SK) inhibitor, increased it. These results suggest that BK, IK, and SK channels might be involved in the proliferation of human dermal fibroblasts, which is inversely related to the channel activation.

로드/언로드 성능향상을 위한 서스팬션의 구조최적화 (Integrated Optimal Design for Suspension to Improve Load/Unload Performance)

  • 김기훈;손석호;박경수;윤상준;박노철;양현석;최동훈;박영필
    • 정보저장시스템학회논문집
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    • 제2권2호
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    • pp.130-137
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    • 2006
  • The HDD(hard disk drive) using Load/unload(L/UL) technology includes the benefits which are increased areal density, reduced power consumption and improved shock resistance than those of contact-start-stop(CSS). It has been widely used in portable hard disk drive and will become the key technology for developing the small form factor hard disk drive. The main objects of L/UL are no slider-disk contact or no media damage. For realizing those, we must consider many design parameters in L/UL system. In this paper, we focus on lift-off force. The 'lift-off' force, defined as the minimum air bearing force, is another very important indicator of unloading performance. A large amplitude of lift-off force increases the ramp force, the unloading time, the slider oscillation and contact-possibility. To minimize 'lift-off' force we optimizes the slider and suspension using the integrated optimization frame, which automatically integrates the analysis with the optimization and effectively implements the repetitive works between them. In particular, this study is carried out the optimal design considering the process of modes tracking through the entire optimization processes. As a result, we yield the equation which can easily find a lift-off force and structural optimization for suspension.

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이황화탄소에 폭로된 근로자들의 말초신경병증에 관한 연구 (A Study of the Peripheral Neuropathy among the Workers Exposed to Carbon Disulfide)

  • 김대성;김순덕;차철환
    • Journal of Preventive Medicine and Public Health
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    • 제26권2호
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    • pp.282-292
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    • 1993
  • Neurotoxicity in the workplace may occur with exposure to scores of chemicals. Although large acute outbreaks of the occupational neurological disease are rare, the incidence of occupational neurotoxicity in its subtler aspects is unknown. A working knowledge of both the major occupational neurotoxic solvents and the tools used by cliniical neurologists and neurotoxicologists to evaluate neurotoxicity in working populations is a necessity fur the occupational physician. To investigate the effects of carbon disulfide($CS_2$) on the peripheral nerve system using the nervous conduction study, 105 male workers working in the spinning room of a viscose rayon factory were examined and compared with a sex and age matched, unexposed 105 male controls using t-test analysis. 72.4% of $CS_2$-exposed workers complained of neurological symptoms, and the abnormal cases in nerve conduction study were 48.6%. The abnormal cases of nerve conduction study increased in number according as the age and duration of exposure increased. In this study, asymptomatic workers were confirmed to have subclinical neuropathy by nerve conduction study. Also as there were abnormal cases even in its duration of exposure below 4 years, nerve conduction study turned out to be ways of discovering of early peripheral neuropathy. In nerve conduction study, the amplitude, velocity, F-wave latency and H-reflex of the motor and sensory nerves in both upper and lower extremities were significant different between $CS_2$-exposed workers and the controls. From the pathological viewpoint, both segmental and axonal degenerations were assumed in this study.

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개선된 선형예측 잔여를 이용한 음성의 잔향음 제거 (Speech Dereverberation using Improved Linear Prediction Residual)

  • 박찬섭;김기만;강석엽
    • 한국정보통신학회논문지
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    • 제11권10호
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    • pp.1845-1851
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    • 2007
  • 배경 잡음과 실내 잔향음은 음성 인식 시스템 성능 저하의 주요 이유이다. 많은 알고리즘이 음성의 잔향음 제거를 위해 개발되었다. 이 논문에서는 실내 환경에서 수정된 선형 예측 잔여(Linear Prediction Residual)를 이용하여 음질 개선을 위한 잔향음 제거 방법을 제안한다. 제안된 잔향음 제거 방법은 음성에서 성문 경계의 순간에 발생한 성도(聲道)시스템의 중요한 여기에 기반한다. 본 논문에서 제안한 방법은 3개의 센서로부터 수집한 반향신호로 각 센서에서의 시간지연 정보를 사용한다. 새로운 선형 예측 잔여신호는 선형 예측 잔여의 가중치와 힐버트 변환으로 얻은, 개선된 선형 예측 잔여 조합을 사용한다. 코히런트하게 더해진 힐버트 포락선의 특징은 잡음과 반사로 인한 큰 진폭 피크를 가지는 것이다. 깨끗한 음성의 잔여는 개선된 음성을 얻는 시변전극 필터를 일으키는데 사용된다. 본 논문에서는 반향 환경에서 성능 분석을 위해 제안된 알고리즘의 시뮬레이션을 수행하였다. 제안된 알고리즘은 실내 잔향환경에서 기존의 알고리즘에 비해 반사된 음성의 품질 향상의 결과를 보였다.

Damage detection of nonlinear structures with analytical mode decomposition and Hilbert transform

  • Wang, Zuo-Cai;Geng, Dong;Ren, Wei-Xin;Chen, Gen-Da;Zhang, Guang-Feng
    • Smart Structures and Systems
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    • 제15권1호
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    • pp.1-13
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    • 2015
  • This paper proposes an analytical mode decomposition (AMD) and Hilbert transform method for structural nonlinearity quantification and damage detection under earthquake loads. The measured structural response is first decomposed into several intrinsic mode functions (IMF) using the proposed AMD method. Each IMF is an amplitude modulated-frequency modulated signal with narrow frequency bandwidth. Then, the instantaneous frequencies of the decomposed IMF can be defined with Hilbert transform. However, for a nonlinear structure, the defined instantaneous frequencies from the decomposed IMF are not equal to the instantaneous frequencies of the structure itself. The theoretical derivation in this paper indicates that the instantaneous frequency of the decomposed measured response includes a slowly-varying part which represents the instantaneous frequency of the structure and rapidly-varying part for a nonlinear structure subjected to earthquake excitations. To eliminate the rapidly-varying part effects, the instantaneous frequency is integrated over time duration. Then the degree of nonlinearity index, which represents the damage severity of structure, is defined based on the integrated instantaneous frequency in this paper. A one-story hysteretic nonlinear structure with various earthquake excitations are simulated as numerical examples and the degree of nonlinearity index is obtained. Finally, the degree of nonlinearity index is estimated from the experimental data of a seven-story building under four earthquake excitations. The index values for the building subjected to a low intensity earthquake excitation, two medium intensity earthquake excitations, and a large intensity earthquake excitation are calculated as 12.8%, 23.0%, 23.2%, and 39.5%, respectively.

TEMPORAL VARIATIONS OF THE GLOBAL SEISMIC PARAMETERS OF HD 49933 OVER A MAGNETIC CYCLE

  • Kim, Ki-Beom;Chang, Heon-Young
    • 천문학회지
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    • 제54권4호
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    • pp.129-137
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    • 2021
  • It has been established that the acoustic mode parameters of the Sun and Sun-like stars vary over activity cycles. Since the observed variations are not consistent with an activity-related origin, even Sun-like stars showing out-of-phase changes of mode frequencies and amplitudes need to be carefully studied using other observational quantities. In order to test whether the presumed relations between the global seismic parameters are a signature of the stellar activity cycle, we analyze the photometric light curve of HD 49933 for which the first direct detection of an asteroseismic signature for activity-induced variations in a Sun-like star was made, using observations by the CoRoT space telescope. We find that the amplitude of the envelope significantly anti-correlates with both the maximum frequency of the envelope and the width of the envelope unless superflare-like events completely contaminate the light curve. However, even though the photometric proxy for stellar magnetic activity appears to show relations with the global asteroseismic parameters, they are statistically insignificant. Therefore, we conclude that the global asteroseismic parameters can be utilized in cross-checking asteroseismic detections of activity-related variations in Sun-like stars, and that it is probably less secure and effective to construct a photometric magnetic activity proxy to indirectly correlate the global asteroseismic parameters. Finally, we seismically estimate the mass of HD 49933 based on our determination of the large separation of HD 49933 with evolutionary tracks computed by the MESA code and find a value of about 1.2M and a sub-solar metallicity of Z = 0.008, which agrees with the current consensus and with asteroseismic and non-asteroseismic data.

An Integrated Approach of CNT Front-end Amplifier towards Spikes Monitoring for Neuro-prosthetic Diagnosis

  • Kumar, Sandeep;Kim, Byeong-Soo;Song, Hanjung
    • BioChip Journal
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    • 제12권4호
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    • pp.332-339
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    • 2018
  • The future neuro-prosthetic devices would be required spikes data monitoring through sub-nanoscale transistors that enables to neuroscientists and clinicals for scalable, wireless and implantable applications. This research investigates the spikes monitoring through integrated CNT front-end amplifier for neuro-prosthetic diagnosis. The proposed carbon nanotube-based architecture consists of front-end amplifier (FEA), integrate fire neuron and pseudo resistor technique that observed high electrical performance through neural activity. A pseudo resistor technique ensures large input impedance for integrated FEA by compensating the input leakage current. While carbon nanotube based FEA provides low-voltage operation with directly impacts on the power consumption and also give detector size that demonstrates fidelity of the neural signals. The observed neural activity shows amplitude of spiking in terms of action potential up to $80{\mu}V$ while local field potentials up to 40 mV by using proposed architecture. This fully integrated architecture is implemented in Analog cadence virtuoso using design kit of CNT process. The fabricated chip consumes less power consumption of $2{\mu}W$ under the supply voltage of 0.7 V. The experimental and simulated results of the integrated FEA achieves $60G{\Omega}$ of input impedance and input referred noise of $8.5nv/{\sqrt{Hz}}$ over the wide bandwidth. Moreover, measured gain of the amplifier achieves 75 dB midband from range of 1 KHz to 35 KHz. The proposed research provides refreshing neural recording data through nanotube integrated circuit and which could be beneficial for the next generation neuroscientists.

직교방식 디지털 고주파기억장치의 다중신호 재생성 효과 (Multi-Signal Regeneration Effect of Quadrature Digital Radio-Frequency Memory)

  • 임중수
    • 융합정보논문지
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    • 제9권8호
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    • pp.134-139
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    • 2019
  • 본 논문은 직교방식(quadrature) 디지털 고주파기억장치의 다중신호 재생성 효과를 기술하였다. 대부분의 고주파기억장치는 단일 신호를 저장한 후 재생성을 잘하지만 다중신호를 저장한 후 재생성할 경우에는 스프리어스 신호가 크게 나타난다. 직교방식 디지털 고주파기억장치는 I채널과 Q채널로 구성되어 있으며 다중신호 재생성시 스프리어스 신호를 크게 줄일 수 있다. 스프리어스 신호크기는 고주파기억장치에서 저장하는 데이터의 비트 수에 따라 달라지며, 본 논문에서는 다중신호에 대해서 고주파기억장치의 저장데이터의 비트 수에 따라 스프리어스 신호의 크기를 구해서 고주파기억장치의 용도에 따른 신호 재생성 비트 수를 구하였다. 본 연구 결과 4 비트 직교방식 디지털 고주파 기억장치는 -20dB 이하의 스프리어스 출력을 얻을 수 있어서 전자전 장비의 신호분석과 재밍장치 개발에 크게 기할 것으로 판단된다.