• Title/Summary/Keyword: Lap On A Chip

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Lap-on-a-chip

  • Kim Tae-Sik;Lee Seong-Ho
    • Electrical & Electronic Materials
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    • v.19 no.10
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    • pp.37-44
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    • 2006
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Recent Progress on Microfluidic Electrophoresis Device Application in Mass Spectrometry

  • Roy, Swapan Kumar;Kim, Seongnyeon;Yoon, Jung H.;Yoon, Yong-Kyu;Cho, Kun
    • Mass Spectrometry Letters
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    • v.9 no.1
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    • pp.1-16
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    • 2018
  • Microfluidic technologies hold high promise and emerge as a potential molecular tool to facilitate the progress of fundamental and applied biomedical researches by enabling miniaturization and upgrading current biological research tools. In this review, we summarize the state of the art of existing microfluidic technologies and its' application for characterizing biophysical properties of individual cells. Microfluidic devices offer significant advantages and ability to handle in integrating sample processes, minimizing sample and reagent volumes, and increased analysis speed. Therefore, we first present the basic concepts and summarize several achievements in new coupling between microfluidic devices and mass spectrometers. Secondly, we discuss the recent applications of microfluidic chips in various biological research field including cellular and molecular level. Finally, we present the current challenge of microfluidic technologies and future perspective in this study field.

Measurement of 3-D Flow inside a Micro Curved-tube using Digital Micro Holographic Particle Tracking Velocimetry (디지털 Micro Holographic PTV기법을 이용한 미세 곡관 내부 3차원 유동 측정)

  • Kim, Seok;Lee, Sang-Joon
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.2579-2584
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    • 2007
  • A digital micro holographic particle tracking velocimetry (HPTV) system consisting of a high-speed camera and a single laser with acoustic optical modulator (AOM) chopper was established. The digital micro HPTV system was applied to water flow in a micro curved-tube for measuring instantaneous 3-D velocity field data consecutively. The micro curved-tube is using to reproduce the dorsal aorta or utilize in various lap-on-a-chip. The temporal evolution of a three-dimensional water flow in the micro curved-tube (the curvature, ${\kappa}$=1/${\phi}$, 2/${\phi}$, 4/${\phi}$, 8/${\phi}$) of 100 ${\mu}m$ and 300 ${\mu}m$ inner diameters was obtained and mean velocity field distribution was obtained by statistical-averaging the instantaneous velocity fields.

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The bonding properties of PDMS - substrate by oxygen plasma treatment ($O_2$ 플라즈마로 표면 처리된 PDMS의 접합특성)

  • Yoo, Kum-Pyo;Kang, Moon-Sik;Pyo, Seong-Yeol;Hong, Suk-In;Min, Nam-Ki
    • Proceedings of the KIEE Conference
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    • 2003.07c
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    • pp.1914-1916
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    • 2003
  • 최근 PDMS를 이용한 미세구조물의 제작을 통한 LOC(lap-on-a-chip) 개발에 대한 연구가 많이 진행되고 있다. 본 연구에서는 PDMS와 여러기판(유리와 실리콘) 사이의 접합 공정에 관한 연구를 하였으며, 특히 PDMS 표면의 물리적, 화학적 변화와 접합 특성과의 관계를 고찰하였다. $O_2$ 플라즈마를 사용하여 표면 처리된 기판의 표면에너지를 접촉각 측정방식으로 측정하였다. 또한 XPS를 이용하여 표면의 화학조성 변화 관찰하였으며, AFM으로 플라즈마 도즈량에 따른 표면 거칠기를 조사하였다.

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Electrowetting of a droplet under an AC Electric Fields (교류전압 하에서의 액적의 전기습윤현상)

  • Hong, Jin-Seok;Ko, Sung-Hee;Kang, Kwan-Hyung;Kang, In-Seok
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.175-176
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    • 2006
  • Electrowetting is prevailing for its various applicability on lap-on-a-chip, and MEMS devices, such as a pump, lens, micro-actuator in the micro-TAS technology. In the usual electrowetting, an AC power is preferred to DC practically. The AC electric field delays the contact angle-saturation, decreases the hysterisis, and is more stable in the view point of dielectric strength. But researches for AC electric field on electrowetting have not been reported very much yet. The different effect of AC on the electrowetting system, especially the effect of a frequency needs to be understood more concretely. In this work, the usual system for electrowetting, water droplet on the dielectric coated electrode (EWOD) is analyzed. Experimental study on the response of contact angles on input frequencies is performed. The simple circuit-model for EWOD system is considered to explain the experimental results. For more concrete understanding, the system is analyzed numerically, where simple AC-conduction model is used. Wetting tensions are analyzed under various input frequency to excavate the experimental results for the responses of the system on input frequencies.

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A Consideration on the Process Technology and Application of MEMS to prepare for upcoming MEMS-based technological paradigm (MEMS 기반의 새로운 기술적 패러다임에 대비한 공정 기술 분석 및 적용에 대한 고찰)

  • Ko, Yun-Seok
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.7
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    • pp.979-986
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    • 2013
  • Recently, in the electric, electronic, robotic, and medical industries, a great attention has been paid to the development of MEMS-based smart devices with a compact size and highly intelligency. The MEMS technology is very effective in designing into a compact size and lightweight by combining into one the complex electrical, mechanical, chemical, and biological features which are required by smart devices, and at the same time, in bulk batch manufacturing. Therefore, this study, to prepare for upcoming new MEMS-based technological paradigm, analyzes MEMS processes and then considers its Applications.

Development of Remote Control Transmission based on an One-chip Microcomputer in Speed Sprayer asture Plant Genetic Resources (원칩 마이크로 컴퓨터(MCS-51)를 이용(移用)한 스피드 스프레이어의 원격조종(遠隔操縱) 변속장치(變速裝置) 개발(開發))

  • Jang, Ik Joo
    • Current Research on Agriculture and Life Sciences
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    • v.8
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    • pp.107-113
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    • 1990
  • This study was attempted to develop a remote controllable speed sprayer in order to protect an operator from agricultural chemicals. For the purpose of remote controllable transmission was developed by using one chip microcomputer. The following results could be summarized in this study. 1. Remote controllable transmission developed had not made even a single mistake during the test performed 100 times repeat. Thus, it could that this machine was very accurate. 2. One chip microcomputer was made by machine language and its was with in 3 sec's which was the same as human did. 3. One chip microcomputer which was used in the experiment could be widely used to automation of agricultural machinery, since it is smaller and chiper than any other similar ones such as personal computer, lap tap, one board computer. 4. Since, farm tractor has the same type of transmission as this system, it also could be adapted to farm tractors. 5. In this experiment, transmission lever was remote controll were designed to operate simultaneously. Thus, this system developed was more complicate than conventional system. However, by removing this transmission lever and by mounting the remote controll system at the speed sprayer, it would be higher and easier to handle than the conventional one.

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