• 한국생산제조학회지
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• 제21권4호
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• pp.608-612
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• 2012

To reduce these costs and time by finite element analysis program has been much research (3~4). At virtual CAE program as like Abaques, Ansys, Ls-dyna and Nastran, the input data of material is got bellow coupon test. In case of carbon composite, it is also put in lamina/laminate properties. There have big problem. If you want to simulate FW(filament winding or wind blade) how do you input material data. Each area of FW is different stacking conditions. It's too hard that each area is tested for inputting lamina or laminate properties. The composite structure increasing load is applied occurred as the matrix dependence of the crack-induced nonlinearity and nonlinear mobility appears since the initial damage. And uni-direction for this research applies the theory to have been confined to. On this study, we are going to get basically fiber properties and matrix than carbon composite properties for simulating according stacking method by GENOA-MCQ. It is help to simulate easily composite material. Also Calculate the matrix nonlinear for simulating non-linear.

• Journal of the Korean Wood Science and Technology
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• 제38권2호
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• pp.85-93
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• 2010

Japanese cedar has low density and poor mechanical performance. Manufacturing glue-laminated timber (glulam) is the best way to compensate for its poor mechanical performance. The Korean Standard (KS) confines outermost lamina of glulam to higher grade than E8, but the yield of higher than grade E8 from logs is only 6.5%. Therefore, the aim of this study is to investigate the possibility of non-Korean-Standard glulam in structural applications. Allowable stresses determined by both hand-calculation and Monte-Carlo simulation show a higher allowable stress than that of the KS-standard glulam of 6S-22B. In the Korean Standard (KS), knot characteristics are not taken into account. Japanese cedar has relatively small knots. We believe that the small knots in Japanese cedar contribute to a higher allowable stress than the KS-standard glulam would predict. The species classification of KS is required to be further subdivided into sub-species groups based on knot characteristics.

• Journal of Korean Neurosurgical Society
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• 제42권6호
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• pp.462-469
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• 2007

Objective : This study characterized the neurons in the lumbosacral cord that express phospho ERK (pERK) after distension or irritation of the bladder, and their relation to the vanilloid receptor 1 (VR1) positive primary afferents. Methods : Mechanical distension and chemical irritation of the bladder were induced by intravesical injection of the saline and mustard oil, respectively. Spinal neurons expressing pERK and the primary afferent fibers were characterized using multiple immunofluorescence for neurokinin 1 (NK1), neuronal nitric oxide synthetase (nNOS) and VR1. Results : Neurons in lamina I, medial dorsal horn (MDH), dorsal gray commissure (DGC) and sacral parasympathetic nucleus (SPN) were immunoreactive for pERK after either mechanical or chemical stimulation. The majority of pERK positive cells were positive for NK1 in lamina I and SPN, but not in the DGC. Most of pERK positive cells are not stained for nNOS except in a small population of the cells in the SPN and DGC. Contacts between perikarya and dendrites of pERK-positive cells and terminals of primary afferents expressing VR1 were identified in lamina I. lateral collateral path (LCP) and SPN. Conclusion : In this study, the lumbosacral neurons activated by mechanical and chemical stimulation of the urinary bladder were identified with expression of the pERK, and also provided the evidence that VR1-positive primary afferents may mediate the activation of these neurons.

• Steel and Composite Structures
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• 제18권6호
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• pp.1465-1478
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• 2015

The effect of cutting off fibers on transient load in a polymeric matrix composite lamina was studied in this paper. The behavior of fibers was considered to be linear elastic and the matrix behavior was considered to be linear viscoelastic. To model the viscoelastic behavior of matrix, a three parameter solid model was employed. To conduct this research, finite difference method was used. The governing equations were obtained using Shear-lag theory and were solved using boundary and initial conditions before and after the development of break. Using finite difference method, the governing integro-differential equations were developed and normal stress in the fibers is obtained. Particular attention is paid the dynamic overshoot resulting when the fibers are suddenly broken. Results show that considering viscoelastic properties of matrix causes a decrease in dynamic load concentration factor and an increase in static load concentration factor. Also with increases the number of broken fibers, trend of increasing load concentration factor decreases gradually. Furthermore, the overshoot of load in fibers adjacent to the break in a polymeric matrix with high transient time is lower than a matrix with lower transient time, but the load concentration factor in the matrix with high transient time is lower.

• IMMUNE NETWORK
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• 제8권2호
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• pp.46-52
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• 2008

Background: Oral tolerance is defined by the inhibition of immune responsiveness to a protein previously exposed via the oral route. Protein antigens exposed via the oral route can be absorbed through the mucosal surfaces of the gastrointestinal tract and can make physical contact with immune cells residing in the intestinal lamina propria (LP). However, the mechanisms of oral tolerance and immune regulation in the intestines currently remain to be clearly elucidated. Methods: In order to determine the effect of oral protein antigen intake (ovalbumin, OVA) on the intestinal LP, we assessed the expression profile of the T cell receptor and the co-receptors on the cells from the intestines of the tolerant and immune mouse groups. Results: We determined that the proportion of OVA-specific B cells and ${\gamma}{\delta}$ T cells had decreased, but the CD8${\alpha}{\beta}$ and D8${\alpha}{\alpha}$ T cells were increased in the LP from the tolerant group. The proportion of CD8＋ T cells in the spleen did not evidence any significant differences between treatment groups. Conclusion: These results indicate that CD8＋ T cells in the intestinal LP may perform a regulatory role following antigen challenge via the oral route.

• International Journal of Aeronautical and Space Sciences
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• 제16권3호
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• pp.360-369
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• 2015

A methodology for determining the design allowables of composite laminates by using lamina level test data and finite element analysis (FEA) is proposed and verified in this paper. An existing method that yields the laminate design allowables by using the complete test results for laminates was improved to reduce the expensive and time-consuming tests. Input property samples for FEA were generated after considering the statistical distribution characteristics of lamina level test data., and design allowables were derived from several FEA analyses of laminates. To apply and verify the proposed method, Hexcel 8552 IM7 test data were used. For both un-notched and open-hole laminate configurations, it was found that the design allowables obtained from the analysis correctly predicted the laminate test data within the confidence interval. The potential of the present simulation to substitute the laminate tests was demonstrated well.

• International Journal of Precision Engineering and Manufacturing
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• 제8권3호
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• pp.64-70
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• 2007

Of all the rapid tooling (RT) methods currently available, thick-layer laminated tooling is the most suitable for large-scale, low-cost dies and molds. Currently, the determination of a lamina's contour or profile and the associated slicing algorithms are based on existing rapid prototyping (RP) data manipulation technology. This paper presents a new adaptive slicing algorithm developed exclusively for profiled edge laminae (PEL) tooling PEL tooling is a thick-layer RT technique that involves the assembly of an array of laminae, whose top edges are simultaneously profiled and beveled using a line-of-sight cutting method based on a CAD model of the intended tool surface. The cutting profiles are based on the intersection curve obtained directly from the CAD model to ensure geometrical accuracy. The slicing algorithm determines the lamina thicknesses that minimize the dimensional error using a new tool shape error index. At the same time, the algorithm considers the available lamination thicknesses and desired lamina interface locations. We demonstrate the new slicing algorithm by developing a simple industrial PEL tool based on a CAD part shape.

• Applied Microscopy
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• 제27권4호
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• pp.391-402
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• 1997

본 연구는 고단백뇨를 보이는 신장질환모델마우스(FGS/Kist mouse)의 사구체에 대한 미세구조학적 변화를 관찰하고자 수행하였다. 전반적으로 사구체내의 모세혈관은 주변부의 혈관사이세포(mesangial cell) 부위의 확장으로 인하여 관강이 좁아져 있었으며 관강내에는 점액양 물질들이 흔히 관찰되었다. 또한 사구체바닥판(basal lamina)이 모세혈관 사이의 공간쪽으로 돌출되어져 있는 소견들도 볼 수 있었다. 혈관사이세포 부위에는 주변부와 뚜렷이 구분되는 전자밀도가 높은 물질들이 많이 차여져 있었다. 한편, 사구체바닥판에 인접하여 존재하고 있는 발세포들(podocytes)은 세포질내 많은 공포들이 관찰되었고, 발세포들이 내고 있는 발세포발(foot process)들은 서로 융합되거나 소실되어 매우 불규칙적인 소견을 보였다.

• Steel and Composite Structures
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• 제19권5호
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• pp.1221-1236
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• 2015

Since the coefficients of thermal expansion (CTE) between concrete and GFRP, steel and GFRP are quite different, GFRP laminates with different laminas stacking-sequence present different thermal behavior and currently there is no specification on mechanical properties of GFRP laminates, it is necessary to investigate the thermal influence on composite girder with stay-in-place (SIP) bridge deck at different levels and on different scales. This paper experimentally and theoretically investigated the CTE of GFRP at lamina's and laminate's level on micro-mechanics scales. The theoretical CTE values of laminas and laminates agreed well with test results, indicating that designers could obtain thermal properties of GFRP laminates with different lamina stacking-sequence through micro-mechanics methods. On the basis of the CTE tests and theoretical analysis, the thermal behaviors of composite girder with hybrid GFRP-concrete deck were studied numerically and theoretically on macro-mechanics scales. The theoretical results of concrete and steel components of composite girder agreed well with FE results, but the theoretical results of GFRP profiles were slightly larger than FE and tended to be conservative at a safety level.

• Journal of Korean Neurosurgical Society
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• 제56권6호
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• pp.475-481
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• 2014

Objective : To evaluate the anatomical feasibility of 3.5 mm screw into the cervical spine in the pediatric population and to establish useful guidelines for their placement. Methods : A total of 37 cervical spine computerized tomography scans (24 boys and 13 girls) were included in this study. All patients were younger than 10 years of age at the time of evaluation for the period of 2007-2011. Results : For the C1 screw placement, entry point height (EPH) was the most restrictive factor (47.3% patients were larger than 3.5 mm). All C2 lamina had a height larger than 3.5 mm and 68.8% (51/74) of C2 lamina had a width thicker than 3.5 mm. For C2 pedicle width, 55.4% (41/74) of cases were larger than 3.5 mm, while 58.1% (43/74) of pedicle heights were larger than 3.5 mm. For pedicle width of subaxial spine, 75.7% (C3), 73% (C4), 82.4% (C5), 89.2% (C6), and 98.1% (C7, 1/54) were greater than 3.5 mm. Mean lamina width of subaxial cervical spine was 3.1 (C3), 2.7 (C4), 2.9 (C5), 3.8 (C6), and 4.0 mm (C7), respectively. Only 34.6% (127/370) of subaxial (C3-7) lamina thickness were greater than 3.5 mm. Mean length of lateral mass for the lateral mass screw placement was 9.28 (C3), 9.08 (C4), 8.81 (C5), 8.98 (C6), and 10.38 mm (C7). Conclusion : C1 lateral mass fixation could be limited by the morphometrics of lateral mass height. C2 translamina approach is preferable to C2 pedicle screw fixation. In subaxial spines, pedicle screw placement was preferable to trans-lamina screw placement, except at C7.