• Title/Summary/Keyword: Laboratory test

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Diagnostic Accordance Rate and Accuracy Between Cytological and Histological Test in Lung Disease (폐질환에 있어 세포검사와 조직검사의 진단 일치율 및 정확도에 대한 조사 연구)

  • Kim, Sung-Chul;Ro, Joung-Whan;Kim, Tai-Jeon
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.4
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    • pp.189-195
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    • 2009
  • Lung cancer is a type of cancer with high mortality; its 5-year survival rate is at a low 14%. Related cytological tests include sputum, bronchial brushing, bronchial washing and fine needle aspiration cytology test etc. From the test specimens in which sputum, bronchial brushing, bronchial washing, and fine needle aspiration cytology were performed, the sensitivity, specificity and accuracy between cytology test and histology test. In the sputum test, sensitivity was 27.71% and specificity was 98.02%, and the bronchial brushing test showed sensitivity of 93.33% and a specificity of 91.3%. The bronchial washing test was a sensitivity of 53.7% and its specificity was 98.9%, and the fine needle aspiration cytology test showed sensitivity and specificity were 88.46% and 72.97%, respectively. In the specimens diagnosed as normal at the sputum test, malignant diagnosis was found in 21 specimens of bronchial brushing, 30 cases of bronchial washings and 37 cases of fine needle aspiration cytology specimens. In the specimens diagnosed as normal at the bronchial washing test, malignant diagnosis was found in 5 specimens of sputum, 7 specimens of bronchial brushin and 1 cases of fine needle aspiration cytology. One specimens found to be normal in fine needle aspiration cytology turned out to maligant in sputum test. The result of this research shows that, in diagnosis lung cancer, a test method of high sensitivity and specificity should be pursued. However, depending on the location and malignancy of the illness, diagnosis may not be obtained in some cases. Therefore, we conclude that the cytological tests performed for lung cancer testing such as sputum, bronchial brushing, bronchial washing, and fine needle aspiration cytology should be carried out in a mutually complementary manner.

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Radar system performance test and Ana lysisusing the Radar Simulative Test & Evaluation Laboratory (레이다 원전계/모의성능 실험실을 이용한 레이다 체계성능 시험 및 분석)

  • Kim, Woo-Sung
    • Journal of the Korea Institute of Military Science and Technology
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    • v.14 no.6
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    • pp.1138-1143
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    • 2011
  • One of the critical items in radar testing is the ability to evaluate the performance of radar systems under real operational environments. But it takes lots of time and cost to operate real targets and analyze the test results due to a large amount of data based on these complicated environments. In this paper, the Radar Simulative T&E Lab. is introduced, and the test and analysis results of the developing radar for predicting the radar system performance are described in the Radar Simulative T&E Lab. This laboratory could be used to test the far-field characteristics of antenna radiation pattern and to perform an effective radar system test and evaluation using a simulative target generator under a low cost repeating test situation.

A Study on the Relationship between Carotid Artery Intima-Media Thickness and Clinical Chemistry Tests (경동맥 초음파 결과와 임상화학 검사의 상관성 연구)

  • Kim, Dae-Sik;Sung, Hyun-Ho;Cho, Eun-kyung;Lee, Jong-Woo
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.4
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    • pp.188-193
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    • 2015
  • Carotid Intima-Media Thickness (CIMT) testing is a test that precisely assesses cerebrovascular and coronary heart diseases. According to many previous studies, CIMT predicts atherosclerosis and is highly correlated to cardiovascular disease risk factors. It has also been reported that CIMT is an independent predictor of risk factors for myocardial infarction and stroke. Therefore, the purpose of this study is to investigate CIMT and other independent factors through a correlation study with the clinical laboratory test results of a blood test. As a result, this study could not prove the correlation between CIMT and risk factors of cardiovascular disease (TC, TG, LDL cholesterol, and HDL cholesterol) due to an insufficient number of subjects. Nevertheless, a positive correlation was demonstrated between CIMT and ALT (p<0.05), GGT (p<0.05), Uric acid (p<0.05), and CEA (p<0.05) at a statistically significant level, suggesting a continuation of the study.

Noninvasive prenatal test for fetal chromosomal aneuploidies by massively parallel sequencing of cell-free fetal DNA in maternal plasma: The first clinical experience in Korea

  • Han, Sung-Hee;Yang, Young-Ho;Ryu, Jae-Song;Kang, Myung-Soo;Kim, Young-Jin;Lee, Kyoung-Ryul
    • Journal of Genetic Medicine
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    • v.12 no.2
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    • pp.85-91
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    • 2015
  • Purpose: Noninvasive prenatal test (NIPT) by massively parallel sequencing (MPS) of cell-free fetal DNA in maternal plasma marks a significant advancement in prenatal screening, minimizing the need for invasive testing of fetal chromosomal aneuploidies. Here, we report the initial clinical performance of NIPT in Korean pregnant women. Materials and Methods: MPS-based NIPT was performed on 910 cases; 5 mL blood samples were collected and sequenced in the Shenzhen BGI Genomic Laboratory to identify aneuploidies. The risk of fetal aneuploidy was determined by L-score and t-score, and classified as high or low. The NIPT results were validated by karyotyping for the high-risk cases and neonatal follow-up for low-risk cases. Results: NIPT was mainly requested for two clinical indications: abnormal biochemical serum-screening result (54.3%) and advanced maternal age (31.4%). Among 494 cases with abnormal biochemical serum-screening results, NIPT detected only 9 (1.8%) high-risk cases. Sixteen cases (1.8%) of 910 had a high risk for aneuploidy: 8 for trisomy 21, 2 for trisomy 18, 1 for trisomy 13, and 5 for sex chromosome abnormalities. Amniocentesis was performed for 7 of these cases (43.8%). In the karyotyping and neonatal data, no false positive or negative results were observed in our study. Conclusion: MPS-based NIPT detects fetal chromosomal aneuploidies with high accuracy. Introduction of NIPT as into clinical settings could prevent about 98% of unnecessary invasive diagnostic procedures.

Weak D Testing is not Required for D- Patients With C-E- Phenotype

  • Choi, Sooin;Chun, Sejong;Lee, Hwan Tae;Yu, HongBi;Seo, Ji Young;Cho, Duck
    • Annals of Laboratory Medicine
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    • v.38 no.6
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    • pp.585-590
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    • 2018
  • Background: Although testing to detect weak D antigens using the antihuman globulin reagent is not required for D- patients in many countries, it is routinely performed in Korea. However, weak D testing can be omitted in D- patients with a C-E- phenotype as this indicates complete deletion of the RHD gene, except in rare cases. We designed a new algorithm for weak D testing, which consisted of RhCE phenotyping followed by weak D testing in C+ or E+ samples, and compared it with the current algorithm with respect to time and cost-effectiveness. Methods: In this retrospective study, 74,889 test results from January to July 2017 in a tertiary hospital in Korea were analyzed. Agreement between the current and proposed algorithms was evaluated, and total number of tests, time required for testing, and test costs were compared. With both algorithms, RHD genotyping was conducted for samples that were C+ or E+ and negative for weak D testing. Results: The algorithms showed perfect agreement (agreement=100%; ${\kappa}=1.00$). By applying the proposed algorithm, 29.56% (115/389 tests/yr) of tests could be omitted, time required for testing could be reduced by 36% (8,672/24,084 min/yr), and the test cost could be reduced by 16.53% (536.11/3,241.08 USD/yr). Conclusions: Our algorithm omitting weak D testing in D- patients with C-E- phenotype may be a cost-effective testing strategy in Korea.

TOA Estimation Technique for IR-UWB Based on Homogeneity Test

  • Djeddou, Mustapha;Zeher, Hichem;Nekachtali, Younes;Drouiche, Karim
    • ETRI Journal
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    • v.35 no.5
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    • pp.757-766
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    • 2013
  • This paper deals with the estimation of the time of arrival (TOA) of ultra-wideband signals under IEEE 802.15.4a channel models. The proposed approach is based on a randomness test and consists of determining whether an autoregressive (AR) process modeling an energy frame is random or not by using a distance to measure the randomness. The proposed method uses a threshold that is derived analytically according to a preset false alarm probability. To highlight the effectiveness of the developed approach, simulation setups as well as real data experiments are conducted to assess the performance of the new TOA estimation algorithm. Thereby, the proposed method is compared with the cell averaging constant false alarm rate technique, the threshold comparison algorithm, and the technique based on maximum energy selection with search back. The obtained results are promising, considering both simulations and collected real-life data.

Characteristics of the Smear Zone by Vertical Drain on Silt (연직배수재에 의한 실트질 지반에서의 스미어 존 특성 평가)

  • Kang, Yun;Kim, Seong-Wook;Yoo, Chan-Ho;Kim, Hong-Taek
    • 한국방재학회:학술대회논문집
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    • 2007.02a
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    • pp.542-545
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    • 2007
  • The vertical drain method generate the disturbed zone, because the drainage should be penetrated into the in-situ ground. The characteristics of the smear zone generated cause the problems that the coefficient of permeability decreases and the consolidation time anticipated in the design is not properly shortened. In this study, in order to understand such influence, the laboratory test were carried out so as to reasonably determine the coefficient of consolidation in silt. For that procedure, mandrel of a diversity were penetrated into the soil tube with silt, and then the variation of pore water pressure was measured with the pore pressure meter, Then, the range of smear effect on silt was estimated with monitoring data through the laboratory test, and also analyzed with inputting the coefficient of consolidation into the theoretical equation.

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FIELD TEST INSTALLATIONS USING N$H_3$SENSOR AND VENTILATION RATE SENSOR FOR CONTINUOUS MEASUREMENT OF TOTAL AMMONIA EMISSION FROM ANIMAL HOUSES

  • Berckmans, D.;Ni, J.Q.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1993.10a
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    • pp.393-402
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    • 1993
  • Two field test installations are discussed. In the first one a new ammonia sensor and an accurate ventilation rate sensor are combined. They are installed in the exhaust chimney in a ventilated pig house. The relative humidity and the room temperature are measured as well. In the second one, an in situ NH$_3$longrightarrowNO converter with subsequent NOx analyser is also being added for accurate ammonia measurement . In this way , the continuous measurement of the total NH$_3$emission can be obtained , the performance of the NH$_3$ sensor can be evaluated, and the ammonia reduction techniques can be tested. The outputs of measurement are fed into a data acquisition system then to a PC in the laboratory. There has been realised the first test installation with which research on the new ammonia sensor is carried out. The primary research results are presented.

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Static Behavior of Reinforced Railway Roadbed by Geotextile Bag (지오텍스타일 백으로 보강된 철도노반의 정적거동 분석)

  • Lee, Dong-Hyun;Shin, Eun-Chul
    • Journal of the Korean Society for Railway
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    • v.9 no.2 s.33
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    • pp.180-186
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    • 2006
  • In this study, a large-scale laboratory model test, 2-D and 3-D numerical analyses were conducted to verify the reinforcement effect by utilizing geotextile bag on the railway roadbed. Static loading which simulated train load was applied on the geotextile bag-reinforced railway roadbed and also unreinforced railway roadbed, Computer program named Pentagon which is a part of FEM programs was used in the numerical analysis. Based on the results of laboratory test, 2-D and 3-D numerical analyses, the effect of load distribution and settlement reduction was found to be depending on the geotextile characteristics, tensile strength of geotextite, and interface friction angle between geotextile bags. In general, the result of 2-D and 3-D numerical analyses shows lower value than that of laboratory test. Also, the result of 3-D numerical analyses shows lower value than that of 2-D numerical analyses because of its stress transfer effect.

Improved Coded Mark Inversion for the Passive Radio Frequency Transmission System of the Electronic Time Fuze

  • Xiong, Dong;Zeng, Xiaoping;Zhao, Xiaogang
    • ETRI Journal
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    • v.31 no.3
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    • pp.348-350
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    • 2009
  • To fit the limited volume and power consumption of the passive radio frequency transmission system of the electronic time fuze, an improved coded mark inversion (CMI) is proposed in this letter. From the performance analysis, the energy transmission efficiency of this encoding method is at least 50% higher than that of CMI and NRZ. Finally, the experiment results show that by adopting this improved CMI, the change of DC voltage through magnetic coupling is lower than 0.2 V when the accuracy of data transmission is above 99.5%.

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