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Bone-Preserving Decompression Procedures Have a Minor Effect on the Flexibility of the Lumbar Spine

  • Costa, Francesco;Ottardi, Claudia;Volkheimer, David;Ortolina, Alessandro;Bassani, Tito;Wilke, Hans-Joachim;Galbusera, Fabio
    • Journal of Korean Neurosurgical Society
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    • v.61 no.6
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    • pp.680-688
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    • 2018
  • Objective : To mitigate the risk of iatrogenic instability, new posterior decompression techniques able to preserve musculoskeletal structures have been introduced but never extensively investigated from a biomechanical point of view. This study was aimed to investigate the impact on spinal flexibility caused by a unilateral laminotomy for bilateral decompression, in comparison to the intact condition and a laminectomy with preservation of a bony bridge at the vertebral arch. Secondary aims were to investigate the biomechanical effects of two-level decompression and the quantification of the restoration of stability after posterior fixation. Methods : A universal spine tester was used to measure the flexibility of six L2-L5 human spine specimens in intact conditions and after decompression and fixation surgeries. An incremental damage protocol was applied : 1) unilateral laminotomy for bilateral decompression at L3-L4; 2) on three specimens, the unilateral laminotomy was extended to L4-L5; 3) laminectomy with preservation of a bony bridge at the vertebral arch (at L3-L4 in the first three specimens and at L4-L5 in the rest); and 4) pedicle screw fixation at the involved levels. Results : Unilateral laminotomy for bilateral decompression had a minor influence on the lumbar flexibility. In flexion-extension, the median range of motion increased by 8%. The bone-preserving laminectomy did not cause major changes in spinal flexibility. Two-level decompression approximately induced a twofold destabilization compared to the single-level treatment, with greater effect on the lower level. Posterior fixation reduced the flexibility to values lower than in the intact conditions in all cases. Conclusion : In vitro testing of human lumbar specimens revealed that unilateral laminotomy for bilateral decompression and bone-preserving laminectomy induced a minor destabilization at the operated level. In absence of other pathological factors (e.g., clinical instability, spondylolisthesis), both techniques appear to be safe from a biomechanical point of view.

Solvent Extraction of Heavy Rare Earth Elements Using PC88A from Synthesis Solution of Low Concentration Rare Earth Solution (저농도 희토류 용액으로부터 PC88A를 이용한 중희토류의 용매추출 연구)

  • Ahn, Nak-Kyoon;Im, Byoungyong;Lee, Jieun;Park, Jae Ryang;Lee, Chan-Gi;Park, Kyung-Soo
    • Resources Recycling
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    • v.26 no.4
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    • pp.26-33
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    • 2017
  • The behavior on the solvent extraction of heavy rare earths (HRE) by using PC88A was confirmed to demonstrate the possibility of recovery on the HRE from industrial wastewater, which consist of low concentration rare earth. We verified the extraction behavior of the HRE through a change of equilibrium pH, extractant concentration and A/O ratio, and also confirmed the stripping behavior depending on the type of mineral acids. At equilibrium pH 1.0, extraction of rare earth (RE) was completed from 95% to 100%. In all extraction conditions, it tend to be extracted in order of high atomic number. When A/O ratio was 10/1, Yb and Tm were concentrated at the maximum and increased 6-fold and 3-fold compared to initial concentration, respectively. To confirm the stripping behavior of the RE, three mineral acids were applied to the organic phase and consequently rate of stripping was increased in order of $HNO_3$, $H_2SO_4$ and HCl.

Physicochemical and Microbiological Properties of Ginseng-Whey Beverages (인삼 유청음료의 이화학적 및 미생물학적 특성)

  • 기해진;홍윤호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.2
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    • pp.208-214
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    • 1993
  • Ginseng-whey beverages were prepared with rennet whey, ginseng, sweetener, honey and Japanese apricot, inoculated with different strains of lactic acid bacteria or unfermented partly. The samples were stored at 4$^{\circ}C$ or 30$\pm$1$0^{\circ}C$ and then physicochemical and microbiological properties were investigated. The yield of whey was 78.8%. The pH-values reduced and acidities increased during the storage period. The contents of solid-substances, ash and lipid in ginseng-whey beverages were 7.90~8.20%, 0.62~0.66% and 0.16%, respectively. The protein contents of ginseng-whey beverages were 0.42~0.56% and the contents were not changed during the storage period. The lactose contents of fermented beverages were higher than those of unfermented beverages. During the storage period (1~5 weeks), the ranges of D(-) - and L(+)- lactic acid contents in fermented ginseng-whey beverages (17.3~156.1 mg/100g, 347.3~1894.2mg/100g) were higher than those of unfermented ginseng-whey beverages (6.2~82.8mg/100g, 7.1~885.5mg/100g). The contents of total saponin in unfermented sample and fermented sample (Lac. casei sub-sp. casei+Str. salivarius sub-sp. thermophilus) were increased during the storage period. But, those of the fermented sample(Lac. acidophilus+Lac. delbrueckii sub-sp. bulgaricus) were reduced. In the electrophoretic results of ginseng-whey beverages, an $\alpha$-lactalbumin and a $\beta$-lactoglobulin bands were shown apparently and there were no changes observed during the storage period. During the storage period (1~3 week) the coliform was not detected and total plate counts and psychrotrophs were increased according to the storage period.

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Carotenoids Components of Tunicata, Shellfishes and Its Inhibitory Effects on Mutagenicity and Growth of Tumor Cell (미색동물 및 패류의 Carotenoids 색소성분과 돌연변이 및 종양세포 증식의 억제효과)

  • 하봉석;백승한;김수영
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.5
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    • pp.922-934
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    • 2000
  • To investigate the composition of carotenoids present in marine organisms and the biological activity of the carotenoids, carotenoids of the muscles and tunic of tunicates and shellfishes were isolated and identified. Anitmutagenic activities of the carotenoids for S. typhimurium TA 98 and cytotoxic activity for cancer cell lines were determined. Total carotenoid contents in the muscle of tunicata ranged from 18.65 mg% to 2.39 mg%. The highest amount of the total carotenoid was found in the muscle of Halocynthia aurantium, followed by Styela clava (HERDMAN), H. roretzi, H. hilgendorfi f. igaboya, H. hilgendorfi f. retteri, S. plicata (LESUEUR) in order. Interestingly, total carotenoid content in the muscle of S. clava (HERDAMAN) was higher than that of H. roretzi. Total carotenoid content of all tunicata, other than H. aurantium and H. roretzi, were higher in muscle than tunic. The major carotenoids in H. roretzi, H. aurantium, S. plicata (LESUEUR), and S. clava (HERDAMAN) were cynthiaxanthin (25.1∼42.2%), halocynthiaxanthin (9.7∼26.3%), diatoxanthin (8.0∼18.7%) and β-carotene (7.7%∼21.7%). Similarly, cantaxanthin (19.6%), cynthiaxanthin (15.4%), halocynthiaxanthin (14.8%), and (3R, 3'R), (3S, 3'S)-astaxanthin (22.6%) in H. hilgendorfi f. retteri and fucoxanthin (26.6%), cynthiaxanthin (21.8%), halocynthiaxanthin (15.2%), and β-carotene (9.3%) in H. hilgendorfi f. igaboya were major carotenoids in both tunicate. However, the composition of carotenoids in muscle and tunic of tunicata was similar each other. Among the shellfishes examined, total carotenoid content of the muscle of Peronidia venulosa (Schrenck) and Corbicula fluminea, and of the gonad of Atrina pinnata and Chlamys farreri, was ranged from 2.51 to 6.83 mg% which were relatively higher than that of other shellfishes. The composition of the carotenoids of shellfishes, which might depend upon their living environments, was varied. But cynthiaxanthin (15.9∼39.0%) and zeaxanthin (9.6∼21.9%) in gonad of C. farreri, and muscles of Buccinum Volutharpa perryi (JAY) and Crassostrea gigas, cynthiaxanthin (21.5∼48.6%) and mytiloxanthin (14.6%) in muscle of C.fluminea and gonad of A. pinnata, and canthaxanthin (60.6%) and isozeaxanthin (20.5%) in muscles of P. venulosa (Schrenck), and β-carotene (23.7%∼37.8%) and zeaxanthin (18.2∼20.4) in muscles of Semisulcospira libertina and Meretrix lusoria were major carotenoids. Interestingly, diester type-carotenoids were present along with free type-carotenoids in muscles of C. gigas. antimutagenic effect of the carotenoids isolated from tunicata and shellfishes against 2-amino-3-methylimidazol [4,5-f]quinoline (IQ) for S. typhimurium TA 98 was proportional to the amount (20, 50 and 100㎍/plate) treated. Mutagenicity of IQ was significantly reduced by astaxanthin, isozeaxanthin, mytiloxanthin and halocynthiaxanthin, whereas the mutagenicity of aflatoxin B₁(AFB₁) was significantly reduced by β-carotene, isozeaxanthin, and mytiloxnthin. Growth inhibition effect of carotenoids isolated from tunicata and shellfishes for cancer cell was proportional to the amount (5, 10, and 20㎍/plate) treated. The growth of HeLa cell by β-carotene, cynthiaxanthin, astaxanthin and halocynthiaxanthin, NCI-H87 cell by β-carotene, astaxanthin, cynthiaxanthin, and halocynthiaxanthin, HT-29 cell by β-carotene, cynthiaxanthin, mytiloxanthin and halocynthiaxanthin, and MG-63 cells by β-carotene, cynthiaxanthin, astaxanthin, canthaxanthin and halocynthiaxanthin were statistically reduced.

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Identification of Lophodermium Species Associated with Needle-cast Disease of Pines in Korea (한국(韓國) 소나무류(類)에 잎떨림병을 일으키는 Lophodermium 속(屬) 균(菌)의 동정(同定))

  • Lee, Seung Gue;Lee, Kyung Joon;La, Yong Joon;Yang, Seong Il;Yi, Chang Keun
    • Journal of Korean Society of Forest Science
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    • v.78 no.2
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    • pp.218-227
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    • 1989
  • Fallen and living pine needles bearing ascocarps were collected throughout the country from February, 1987 to October, 1988 to identify and describe Lophodermium species associated with Lophodermium needle cast disease of pines in Korea. All of the observed characteristics of given species were compared with published descriptions of the Lophodermium species. As a result of this study, six Lophodermium species were identified and described. L. pinastri was previously recorded while the other five species, i.e., L. australe, L. durzlabrum, L. nitens, L. pini-excelsae and L. pini-pumilae, were unrecorded in Korea. One Lophodermium species has not been fully identified in this study, and tentatively named as L. sp-1. L. australe was observed on the needles of Pinus rigida, P. rigida ${\times}$ taeda and P. taeda, L. pini-excelsae on P. parviflora and P. strobus, L. nitens, L. durilabrum and L. pini-pumilae on P. koraiensis, L. sp-1 on P. thunbergii and L. pinastri on P. densiflora and P. taeda. L. sp-1 was collected from the diseased regions of 2-year-old needles of P. thunbergii and L. durilabrum from P. koraiensis, suggesting pathogenic nature of these fungi.

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A study on the face pressure control and slurry leakage possibility using shield TBM model test (축소 모형실험을 통한 토피조건별 이수압식 쉴드 TBM의 챔버압 및 이수분출 가능성 평가)

  • Koh, Sungyil;Shin, Hyunkang;La, You-Sung;Jung, Hyuksang
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.3
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    • pp.277-291
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    • 2020
  • Shield TBM is a tunnelling method that has a wider range of applications in the poor ground condition compared to conventional tunnels (Drill and Blast). Currently, a 13.3 m large-diameter slurry shield TBM is preparing for construction to pass under the Han River. Shield TBM is divided into slurry and EPB shield TBM, and management items during construction are different depending on each characteristic. In this paper, the equipment type, origin, application case and trouble case were analyzed for slurry shield TBM, which is mainly constructed in soft ground. In addition, 2D and 3D model tests were conducted on the condition of soil depth for the possibility of slurry leakage into front of the equipment, with appropriate chamber pressure. Based on this paper, it proposed to provide basic and reference data for proper excavation surface pressure and chamber pressure during construction of slurry shield TBM under soft ground conditions, and proposed measures to minimize stability and environmental decline due to slurry ejection.

A Study Regarding Measurements of Bacterial Contamination Levels in Radiology Room Equipment (방사선과 촬영실 장비의 세균오염도 측정)

  • Choi, Eun-Jin;Song, Hyeon-Je;Dong, Kyung-Rae;Kim, Chang-Bok;Ryu, Jae-Kwang;Kwak, Jong-Gil
    • Journal of Radiation Industry
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    • v.11 no.1
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    • pp.1-6
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    • 2017
  • Reported some level of bacteria in areas that are well made contact in Radiology imaging room evaluate the importance of cleanliness in the hospital management of equipment to check for the presence of pathogenic bacteria. Gwang-ju and Jeol-la city and medium-sized hospitals in the material with a cotton swab and rub evenly Radiology selection cassette, a handle, Apron of the imaging apparatus having the most contact with patients from July 2016 to August 2016 as a target in place and special studios 6, and saline solution will placed in a test tube containing. The swab sample was diluted 1,000 times, you can see the bacteria and the intestinal bacterial selective medium Trypticase Soy Agar (TSA), Muller-Hinton Agar (MHA), Eosin-Methylene Blue (EMB), ENDO(BD, NJ, USA) then incubated smear to. In the incubator (incubator, SANYO, Japan) was observed after incubation of bacteria and counting the total number of bacteria also Colonies (colony) suspected intestinal bacteria were isolated and cultured on KIA medium (BD, NJ, USA). As a result, it was found that this came Gram positive Coccus A hospital handle the F hospital, from the C Gram positive Coccus cassette and handle the F hospital. The striking yellow coloring Staphylococcus aureus 110 agar (STA 110) in the medium sample, but it is suspected staphylococcal Coccus to the final identification in the laboratory is not a single specimen of the two samples from Gram positive Coccus biochemical identification Identification Kit is an API could not, it was thought to be non-Staphylococcus aureus was cultured on blood agar suggesting that (BAP) blood of dance. Dynamic tests were conducted biochemical API kit of the two samples were identified from Gram positive Coccus bacteria Escherichia coli (E. coli) is F hospital cassette was confirmed Eenterobacter cloaca in A hospital possession. Did not aggregate O-26, O-111, O-157 and the serum test was conducted in the laboratory from the E. coli F cassette hospital.

On characteristics of environmental correction factors in the South Indian Ocean by Topex/Poseidon satellite altimetric data (Topex/Poseidon 위성의 Altimeter자료를 이용한 남인도양의 환경보정인자 특성에 관한 연구)

  • 윤홍주;김영섭;이재철
    • Korean Journal of Remote Sensing
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    • v.14 no.2
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    • pp.117-128
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    • 1998
  • Topex/Poseidon satellite, launched in Auguest 1992, has provided more 5 years of very good quality data. Efficient improvements, either about instrumental accuracy or about sea level data correction, have been made so that Topex/Poseidon has become presently a wonderful tool for many researchers. The first mission data of 73 cycles, September 1992 - August 1994, was used to our study in order to know characteristics of environmental correction factors in the Amsterdam-Crozet-Kerguelen region of the South Indian Ocean. According to standard procedures as defined under user handbook for sea surface height data processes, then we have chosen cycles 43 as the cycle of reference because this cycle has provided the completed data for measurement points and has presented the exacted position of ground track compared to another cycles. It was computed variations of various factors for correction in ascending ground track 103(Amsterdam-Kerguelen continental plateau) and descending ground track170 (Crozet basin). Here the variations of ionosphere, dry troposphere, humid troposphere, electromagnetic bias, elastic tide and loading tide were generally very smaller as a few of cm, but the variations of oceanic tide(30-35cm) and inverted barometer(15-30cm) were higher than another factors. For the correction of ocean tide, our model(CEFMO: Code d' Elements Finis pour la Maree Oceanique) - This is hydrodynamic model that is very well applicated in all oceanic situations - was used because this model has especially good solution in the coastal and island area as the open sea area. Conclusionally, it should be understood that the variation of ocean free surface is mainly under the influence of tides(>80-90%) in the Amsterdam - Crozet- Kerguelen region of the South Indian Ocean.

A positive interpretation of Louis Lavelle for the Presence of Evil and Pain, and its Limitations - Focusing on evil and suffering - (루이 라벨의 '악의 현존과 고통'에 대한 긍정적인 해석 그리고 그 한계 - 『악과 고통들』을 중심으로 -)

  • Lee, Myoung-gon
    • Journal of Korean Philosophical Society
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    • v.146
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    • pp.163-192
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    • 2018
  • In the philosophy of Louis Labelle, the subject of "good and evil", which is rarely discussed in modern philosophy, emerges as a very important concept. In his reasoning, the notion of evil starts from a passive stipulation of the Scholastic philosophy of "the lack of being", but he defined the evil, which actually exists in the world with more positive sense as a willing force destroying "life and values". In his reasoning that defines "the presence of evil" as "le scandale du monde", all humans have the possibility of evil as an attitude of will, and the presence of evil in the world and in human society is inevitable. On the other hand, because the outcome of evil appears as physical and mental "pain", the human's attitude toward pain, which attempts to deny suffering, induces a moral will to overcome this evil. The moral anguish, which is the "internal suffering" that we have in front of the presence of evil, makes us conscious of becoming a "moral being", and people become self-satisfied here. Although painful, self-satisfaction and happiness about becoming a moral being is the only occasion and motive for man to overcome this by opposing the presence of evil. In other words, Lavelle's thoughts for good and evil are based on "moral psychologism", and the "coherence of psychological horizons and ethical horizons" between rejection of suffering and moral agony enables "ethical optimism" that man constantly overcomes evil and produces good. This is clearly an advanced modern application of scholasticism on the concept of evil.

Prediction of Water Qualities and Heavy Metals by Application of Water Quality Improvement Plans in Rimac River, Peru (페루 리막강 수질개선 대책에 따른 수질 및 중금속 예측 연구)

  • Yi, Hye-Suk;Chong, Sun-A;Lee, Sanguk;Lee, Yosang
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.497-497
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    • 2016
  • 페루의 Rimac강은 수도인 Rima시를 관통하는 강으로 각종 용수공급 등의 기능을 담당하는 중요한 강이지만 광산, 공장 및 도시 등 점?비점오염원으로 인해 오염이 심각해지고 있는 실정이다. 본 연구에서는 Rimac강의 하천복원을 위하여 3단계 수질개선 목표를 설정하고 각 단계별 BOD, TP 및 중금속(Al, As, Cd, Fe) 예측을 수행함으로써 목표달성 가능 평가를 수행하였다. Rimac강 지류인 Rio Santa Eulalia 하천 유입후부터 하구까지 총 57 km를 대상으로 4개의 대구간(Reach), 57개의 소구간(Element)으로 구분하여 QUAL2E 모델을 구축하였다. 2013년을 대상으로 저유량시기(건기)인 12월과 고유량시기(우기)인 1월을 대상으로 BOD, TP, Al, As, Cd, Fe의 모델 재현성을 검토한 결과, Rimac강 하류의 Huaycoloro강 유입이후 BOD, TP가 증가하는 현상을 적절히 재현하는 것으로 나타났다. 중금속은 Romac강 상류와 하류 Huaycoloro강 유입 수질 농도차이가 크지 않아 거리별로 일정한 농도를 나타내는 것으로 모의되었으나 실측정값은 하구로 갈수록 낮아지는 경향이 다소 나타났지만 대체적으로 실측값의 경향을 따르는 것으로 모의되었다. 수질개선 시나리오는 1단계(2016-2018년), 2단계(2019-2021년) 및 최종 3단계(2022-2024년)로 구분하여 저유량시기와 고유량시기의 수질개선 대책에 따른 수질변화를 예측하여 Rimac강 하류의 대표 지점인 La Atargea 취수장 지점에서 목표수질 달성여부를 평가하였다. 저유량시기의 경우, BOD는 1단계 이후 5.9 mg/L에서 목표수질 5.0 mg/L 이하로 농도가 감소되었으며 최종 3단계에 2.2 mg/L로 63.3% 개선하는 것으로 예측되었다. TP는 1단계 25.8% 개선, 3단계는 51.6% 개선되어 목표수질인 0.15 mg/L를 만족하는 것으로 예측되었다. 중금속의 경우 Cd는 당초 수질목표를 만족시키는 상황이었으며 그 외 항목은 Al>As>Fe 순으로 개선효과가 나타났고, 3단계 이후 모두 목표수질을 달성할 것으로 예측되었다. 고유량시기 수질예측 결과, 1단계 BOD, TP는 약 49, 19% 저감효과가 나타났으며 3단계 이후 57, 25%까지 개선되는 것으로 예측되어 목표수질을 만족시키는 것으로 분석되었다. 중금속은 Al이 가장 큰 개선 효과가 나타났으며 3단계에서 77.5%의 개선 효과가 분석되었다. 페루 리막강 유역 수질개선 대책 수립에 따른 수질개선효과 분석 결과, 3단계까지 모든 수질항목의 목표수질 달성이 가능한 것으로 분석되었으나 TP, Al 및 As의 경우에 2단계까지 목표수질 달성이 어려워 더욱 체계적인 관리가 필요할 것으로 판단되었다.

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