• Title/Summary/Keyword: LTS

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Homology Modeling of Cysteinyl Leukotriene1 Receptor

  • Babu, Sathya;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.8 no.1
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    • pp.13-18
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    • 2015
  • Cysteinyl leukotrienes are inflammatory mediators having important role in pathophysiological conditions such as asthma, allergic rhinitis and have been implicated in a number of inflammatory conditions including cardiovascular and gastrointestinal diseases. Most of the disease regulatory actions of the CysLTs are mediated through CysLT1 receptor. Hence in the present study, homology modeling of CysLT1 was performed because the availability of 3D structure would enhance the development of new drugs for inflammatory diseases. However the templates identified have low sequence identity which increases the complexity of modeling. Hence, homology modeling was performed using single template, multiple templates and also using threading I-TASSER server. The best model was selected based on the validation of the generated models using Ramachandran and ERRAT plot. The model developed could be useful for identifying crucial residues and docking study.

The development of the landmark tracking system

  • Lee, Eun Ho;Dickerson, Steve
    • 제어로봇시스템학회:학술대회논문집
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    • 1991.10b
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    • pp.1894-1898
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    • 1991
  • A landmark tracking system(LTS) has been developed for use in locating objects in a manufacturing environment. The Landmark Tracking System is an integrated system which consists of a grey scale CCD camera, an image processor, an illumination system based on electronic flash, and software intended primarily for tracking retroreflective landmarks. The term "integreated" means that the camera electronics and the strobe electronics are directly linked to the computer system, governed by the same clock and under direct software control. A novel element in the LTS is that a pinhole is used for the optics.he optics.

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Development for Verification Tool Guaranteeing Reliability of Rail Signal Control Protocol (신뢰성확보를 위한 철도 신호제어용 프로토콜 검정기 개발)

  • Seo, Mi-Seon;Hwang Jin-Ho;Hwang Jong-Gyu;Lee Jae-Ho;Kim Sung-Un
    • Proceedings of the KSR Conference
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    • 2004.06a
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    • pp.1452-1455
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    • 2004
  • In this paper, we develope a protocol verification tool that verifies the correctness of rail signal control protocol type 2 specified in LTS(Labeled Transition System) by using model checking method. This tool automatically checks several properties for deadlock, livelock and reachability of states and actions on LTS. and removes many errors and ambiguities of an informal method used in the past, so saves down expenditures and times required in the protocol development. Therefore it is expected that there will be an increase in safety, reliability and efficiency in terms of the maintenance of the signaling system by using the developed verification tool.

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Design and Fabrication of BSCCO-2223 Field Coils for Superconducting Synchronous Rotating Machine (초전도 동기기용 BSCCO-2223 계자코일의 설계 및 제작)

  • 백승규;장현만;손명환;권영길;류강식;조영식
    • Proceedings of the Korea Institute of Applied Superconductivity and Cryogenics Conference
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    • 2001.02a
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    • pp.104-107
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    • 2001
  • Racetrack coils are used in many areas of superconductivity applications such as generators, motors, maglev, wiggler magnets and so on. Especially now a days a few advanced nations including U.S., Japan are developing high temperature superconducting(HTS) wire which has better performance than low temperature superconducting(LTS) wire. Most of HTS wires such as BSCCO-2223 are manufactured with PIT(Power In Tube) process, so the shape of the wire looks like tape different from LTS wire with round cross-sectional appearance like normal conductors. Generally HTS racetrack coils are composed of a few partial double-pancake colis and then the double-pancakes are jointed each other according to their applications.

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Docking Study of Cysteinyl Leukotriene 1 Receptor: Therapeutic Target for Allergy

  • Babu, Sathya
    • Journal of Integrative Natural Science
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    • v.9 no.4
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    • pp.228-233
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    • 2016
  • Cysteinyl leukotrienes are inflammatory mediators having important role in pathophysiological conditions such as asthma and allergic rhinitis. CysLT1 receptor mediates most of the disease regulatory actions of the CysLTs and it is been implicated in a number of inflammatory conditions including gastrointestinal and cardiovascular diseases. Hence in the present study, molecular docking of CysLT1 was performed with its potent and orally efficacious antagonist CP-199330 and CP-199331. The aim of this study was to compare the interaction of CP-199330 and CP-199331 with known drugs such as Zafirlukast, Pranlukast and Montelukast which had already showed clinical efficacy in the treatment of asthma. The residues such as TYR83, GLN274, LYS311 and SER313 were found to interact with both the antagonist and the known drugs. Also, we noticed the docking scores and interaction of the antagonists were comparable with the known drugs. Hence these antagonists could serve as better drugs for the treatment of allergy.

Channel Equalization Algorithms for an WAVE System (WAVE 시스템을 위한 채널 등화 기법)

  • Kim, Yong-Sung;Seo, Chang-Woo;Hong, Dae-Ki
    • Proceedings of the KAIS Fall Conference
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    • 2008.11a
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    • pp.326-329
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    • 2008
  • 현재 IEEE 802.11p 규격은 기존의 IEEE 802.11a 규격을 기반으로 하여 표준화가 진행되고 있다. 기존의 IEEE 802.11a 규격은 무선랜 (WLAN: Wireless Local Area Network) 규격으로서 고속으로 이동하는 차량 통신환경 즉 WAVE (Wireless Access for Vehicular Environment) 환경에 그대로 작용할 경우 수신 성능이 급격히 떨어지게 되 는 문제점이 있다. 본 논문에서는 긴 훈련 심볼 (LTS: Long Training Sequence)을 이용하는 기존의 채널 추정 기법을 기반으로 하되 WAVE 채널처럼 빠르게 변화하는 채널에 대응하기 위해 일정한 심볼 주기 마다 미드엠블 (Mid-Amble)을 삽입하는 전송구조를 제안한다. 또한, 미드엠블 사이의 심볼들의 위상과 크기를 3차원 스플라인 보간법을 적용하여 추정하는 알고리듬을 제안한다. 제안된 알고리듬의 성능실험을 위해 WAVE 채널을 모델링하였으며 이러한 채널에서 성능실험을 수행하였다. 실험결과에 의하면 제안된 알고리듬은 빠른 시변 채널에서도 매우 우수한 성능을 나타냄을 알 수 있다.

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Design and Fabrication of 5 T HTS Insert Magnet (5 T급 고온초전도마그넷의 설계 및 제작)

  • Ku, M.H.;Kim, D.L.;Choi, Y.S.;Cha, G.S.
    • Progress in Superconductivity and Cryogenics
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    • v.14 no.3
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    • pp.28-32
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    • 2012
  • The critical current of the HTS(High Temperature Superconductor) tape is governed by cooling temperature, magnetic field and its angle to HTS tape originated from its geometrical structure. At the HTS coil design stage, the critical current of the coil is calculated by considering the Ic-B characteristics of the 2G tape and the operating current is determined based on the critical current. The operating current and the structure of the 5 T coil are suggested through the FEM (Finite Elements Method) analysis and calculation. As a part of our on-going research on a 20 T LTS/HTS magnet, we have designed and constructed a 5 T HTS insert coil and tested it in liquid helium temperature.

Design and Fabrication of High-Tc Superconducting Field coils (고온초전도 계자코일의 설계 및 제작)

  • Baik, S.K.;Jang, H.M.;Ko, R.K.;Sohn, M.H.;Kwon, Y.K.;Ryu, K.S.;Jo, Y.S.
    • Proceedings of the KIEE Conference
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    • 2000.07b
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    • pp.775-777
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    • 2000
  • Superconducting racetrack coils are used in areas of generators, motors, wiggler magnets and so on. Especially now a days many advanced nations including U.S., Japan are developing high temperature superconducting(HTS) wire which has better performance than low temperature superconducting(LTS) wire. Most of HTS wires such as Bi-2223 are manufactured with PIT(Power In Tube Method) process, so the shape of the wire looks like tape different from LTS wire of round shape as normal conductors. Generally HTS racetrack coils are composed of a few partial double-pancake colis and then the double-pancakes are jointed each other according to their applications.

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Taiwanese Science Curriculum Reform and Earth System Education

  • Chang, Chun-Yen
    • 한국지구과학회:학술대회논문집
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    • 2003.09a
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    • pp.3-10
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    • 2003
  • Curriculum reform has been a significant emphasis for most of countries all over the world for the past few years. It was the first time for Taiwan to develop a new Science and Life Technology curriculum Standards (SaLTS) for grades 1 through 9 compulsory educations. The SaLTS features integrated science content with the aim at motivating students to learn science and encouraging students to apply science to their everyday life, which is practically well aligned with the philosophical essence and foundations of Earth Systems Education (ESE). This paper calls attention to the importance of the inclusion of ESE into the forthcoming science curricula of Taiwan and worldwide and provides some exemplary ESE-inspired curriculum and instructional modules that have been successfully implemented in the secondary schools of Taiwan. Hopefully, this paper can shed some lights on the future development of the ESE-based science curricula, instructional modules, and teacher preparation programs.

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Laser Processing Technology in Semiconductor and Display Industry (반도체 및 디스플레이 산업에서의 레이저 가공 기술)

  • Cho, Kwang-Woo;Park, Hong-Jin
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.6
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    • pp.32-38
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    • 2010
  • Laser material processing technology is adopted in several industry as alternative process which could overcome weakness and problems of present adopted process, especially semiconductor and display industry. In semiconductor industry, laser photo lithography is doing at front-end level, and cutting, drilling, and marking technology for both wafer and EMC mold package is adopted. Laser cleaning and de-flashing are new rising technology. There are 3 kinds of main display industry which use laser technology - TFT LCD, AMOLED, Touch screen. Laser glass cutting, laser marking, laser direct patterning, laser annealing, laser repairing, laser frit sealing are major application in display industry.