• Journal of the Korea Furniture Society
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• v.20 no.4
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• pp.339-357
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• 2009

Probability based design(PBD) method is independent of construction materials and uses real material properties unlike allowable stress design(ASD) that depends on small clear specimen property, also give quantitative safety and endurance lifetime of a certain material. Moreover, almost advanced country accepted PBD method instead of ASD method. So it is urgent to convert the current ASD method into the PBD method. However, there are wholly lacking of domestic researches related to current issue, and to solve several points in ASD method and to take advantage of PBD method, the conversion from the ASD method into the PBD method is a worldwide trend. Other domestic construction codes, such as steel or concrete constructions, accept the PBD method as well. Accordingly, to introduce PBD method into wood structural design, general theory, and preliminary data and methods were reviewed. With keeping this in mind, some important contents were reviewed, sorted some points for wood structural design that have distinctions against the other construction materials. Furthermore, the history of PBD method, and statistical data and theories for the PBD method, and preliminary data of resistance and load that are two random variables for the PBD method, and finally the difference between limit state design(LSD) and load and resistance factor design(LRFD) that were two superpowers in the PBD method.

• ETRI Journal
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• v.39 no.3
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• pp.398-405
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• 2017

In this paper, an artificial stereo extension method that creates stereophonic sound from a mono sound source is proposed. The proposed method first trains deep neural networks (DNNs) that model the nonlinear relationship between the dominant and residual signals of the stereo channel. In the training stage, the band-wise log spectral magnitude and unwrapped phase of both the dominant and residual signals are utilized to model the nonlinearities of each sub-band through deep architecture. From that point, stereo extension is conducted by estimating the residual signal that corresponds to the input mono channel signal with the trained DNN model in a sub-band domain. The performance of the proposed method was evaluated using a log spectral distortion (LSD) measure and multiple stimuli with a hidden reference and anchor (MUSHRA) test. The results showed that the proposed method provided a lower LSD and higher MUSHRA score than conventional methods that use hidden Markov models and DNN with full-band processing.

• Journal of the Ergonomics Society of Korea
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• v.31 no.6
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• pp.741-747
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• 2012

Objective: The purpose of this study is to compare the EMG activities of the trunk muscles when carrying a backpack with belts and without belts. Background: This research aimed to explore the influence of carrying a backpack with belts on the trunk muscles activity and to suggest a desirable method of wearing backpacks. Method: Seventy five adolescents participated in this study. The EMG activities of upper trapezious, cervical erector spinae and rectus abdominis were collected. One way ANOVA was used to analyze the collected data. LSD was used for post-hoc test. Results: The EMG data from treadmill walking showed significant differences between carrying a backpack with belts and without belts for the cervical erector spinae and upper trapezious(p<.05) in all group(A Group: no belt, B Group: lumbar belt, C Group: lumbar-chest belt). In descending walking, significant difference were found for the cervical erector spinae and rectus abdominis in all group. In ascending walking, there were no significant differences in all group. LSD showed that the muscle activity of the trunk muscles decreased significantly when the lumbar belt and lumbar-chest belt were worn. Conclusion: The trunk muscles activities were decreased when the subjects were wearing a backpack with belts, comparing with wearing a backpack without belts. Application: These results can be used to provide useful information on how wearing a backpack in adolescent.

• Speech Sciences
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• v.15 no.2
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• pp.169-176
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• 2008

This study was intended to analyze difference of vocal folds movements between upon wakeup and in several hours later in the morning. The difference of vocal fold movements was compared with fundamental frequency and a range of fundamental frequencies from maximum to minimum. The participants were 30 female adults between 20 and 29 years old. Voice samples were collected from their reading sentence (Jeong, 1993). The first sampling was conducted within 5 minutes after wakeup, while the second on 1 hour after the first sampling. Finally, the third voice sample was collected on 6 hours after the second sampling. The results of this study were as follows: First, fundamental frequency of the participants were by hour significantly time-dependent(F=7.843). Post-hoc multiple comparison (LSD) was conducted to determine when the difference could be observed. The result showed significant differences between upon wakeup and 6 hours later (p< .001) and between 1 hour later and 6 hours later (p< .05). Second, there were a significantly time-dependent ranges of fundamental frequencies of participants by hour (F=3.130). According to the results of the LSD analysis the significant differences in range of fundamental frequencies were found between upon wakeup and 1 hour later and also between wakeup and 6 hours later (p< .05). The results above indicate that vocal fold movements upon wakeup is different from those of several hours later.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.4C
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• pp.342-349
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• 2008

This paper presents a new digit-serial systolic multiplier over $CF(2^m)$ for cryptographic applications. When input data come in continuously, the proposed array produces multiplication results at a rate of one every ${\lceil}m/D{\rceil}$ clock cycles, where D is the selected digit size. Since the inner structure of the proposed array is tree-type, critical path increases logarithmically proportional to D. Therefore, the computation delay of the proposed architecture is significantly less than previously proposed digit-serial systolic multipliers whose critical path increases proportional to D. Furthermore, since the new architecture has the features of regularity, modularity, and unidirectional data flow, it is well suited to VLSI implementations.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.7
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• pp.119-124
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• 2015

Speech enhancement has been required as a preprocessor for a noise robust speech recognition system. Codebook-based Speech Enhancement (CBSE) is highly robust in nonstationary noise environments compared with conventional noise estimation algorithms. However, its performance is severely degraded for the codevector combinations that have lower correlation with the input signal since CBSE depends on the trained codebook information. To overcome this problem, only the reliable codevector combinations are selected to be used to remove the codevector combinations that have lower correlation with input signal. The proposed method produces the improved performance compared to the conventional CBSE in terms of Log-Spectral Distortion (LSD) and Perceptual Evaluation of Speech Quality (PESQ).

• BMB Reports
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• v.55 no.11
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• pp.541-546
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• 2022

The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is crucial for maintaining genomic integrity and is involved in numerous fundamental biological processes. Post-translational modifications by proteins play an important role in regulating DNA repair. Here, we report that the methyltransferase SET7 regulates HR-mediated DSB repair by methylating TIP60, a histone acetyltransferase and tumor suppressor involved in gene expression and protein stability. We show that SET7 targets TIP60 for methylation at K137, which facilitates DSB repair by promoting HR and determines cell viability against DNA damage. Interestingly, TIP60 demethylation is catalyzed by LSD1, which affects HR efficiency. Taken together, our findings reveal the importance of TIP60 methylation status by SET7 and LSD1 in the DSB repair pathway.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.316-316
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• 2017

The objective of this study is to estimate quantitatively soil salinity and soil loss at upland soils in agriculture land region in Saemangeum reclaimed land on the south Korea coasts. Soil loss and soil salinity are the most critical problem at reclaimed tidal saline soil in Korea. The several thematic maps of research area such as land cover map, topographic and soil maps, together with tabular precipitation data used for soil erosion and soil salinity calculation. Meteorological data were measured directly as air temperature, wind speed, solar radiation, and precipitation. The experiment was conducted 2% sloped lysimeter ($5.0m{\times}20.0m$) with 14 treatments and it were separated by low salinity division (LSD) and high salinity division (HSD) install. The cation content in ground water increased during time course, but in the case of land surface water the content was variable, and $K^+$ was lower than that of $Na^+$ and $Mg^{2+}$. At the LSD under rainproof condition, the salinity was directly proportional to soil water content, but at the HSD the tendency was no reversed. In condition of rainproof, the amount of soil salinity was higher at the HSD than at the LSD. Positive correlation was obtained between the soil water content and available phosphorous content at the rainfall division, but there was no significance at the surface soil of the rainproof division. Sodium adsorption ratio and anion contents in soil were repressed in the order of vinyl-mulching > non-mulching > bare field. According to the result of analyzing soil loss, soil loss occurred in a vinyl-mulching, a non-mulching and a bare field in size order, and also approximately 11.2 ton/ha soil loss happened on the reclaimed land area. The average soil loss amount by the unit area takes place in a non-mulching and bare field a lot. Our results indicate that soluble salt control and soil erosion are critical at reclaimed tidal saline soil and the results can provide some useful information for deciding management plans to reduce soil loss and salt damage for stable crop production and diverse utilization or cultivation could be one of the management options to alleviate salt damage at reclaimed tidal saline soil in Korea.

• Journal of Periodontal and Implant Science
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• v.30 no.2
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• pp.359-374
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• 2000

Cyclosporine A(CsA) is a widely used immunosuppressant for transplant patients and is also used for the treatment of a wide variety of systemic diseases with immunologic disorders. However, its use is frequently limited because of complications such as nephrotoxicity or gingival hyperplasia. Although several hypotheses have been postulated for CsA-induced gingival hyperplasia, i.e. various cytokine effects of inflammatory cells, existence of plaque or CsA itself, but its pathogenesis is still unclear. For experimental chronic CsA toxicity, salt depletion has been shown to increased susceptibility of rodents to the effects of CsA, and this maneuver facilitates production of arteriolopathy and interstitial fibrosis in kidney that mimic the changes found in human. The purpose of this study was to evaluate pathogenesis of CsA-induced gingival hyperplasia by comparing changes between CsA administration groups of normal standard diet and those of low salt diet group. Specific pathogen-free, 20 to 25 days old(120 to 150 g), male Fisher-344 rats(KIST, Korea), 120 to 150g of body weight, were assigned to four groups of six animals each after one week of adaptation period for powder food. Group 1 received olive oil($300{\mu}l/g\;of\;diet$) with normal standard diet(0.4% of sodium)(NSD). Group 2 received CsA(Cypol-N, Jonggundang, Korea; $300{\mu}g/g\;of\;diet$) with normal standard diet(NSD+CsA). Group 3 received same amount of olive oil with low salt diet(0.05 % of sodium, Teklad Premier, U.S.A.)(LSD). Group 4 received same dose of CsA with low salt diet(LSD+CsA). Rats were pair fed and were sacrificed after six weeks. Renal histologic lesions associated with CsA, consisted of cortical interstitial fibrosis, tubular atrophy and hyalinization of arterioles and the impairment of renal function including increase of serum creatinine and decrease of glomerular filtration rate was more severe in low salt diet group. These were proved as the results of activated of renin-angiotensin system in the kidney by low salt condition. Meanwhile the degree of gingival hyperplasia at incisor and molar tooth was less severe in low salt diet group compared with normal sodium diet group. Hyperplastic gingiva showed mild epithelial hyperplasia and expanded underlyng stroma which consisted of matrix increasement, capillary proliferation and dilatation. While the number and the activation of fibroblasts were increased, inflammatory cells were rare in the stroma. The immunohistochemistry for TGF-${\beta}_1$ in the kidney and gingiva revealed stronger positive in LSD+CsA in kidney but in gingiva of NSD+CsA. These results suggested followings; Gingival hyperplasia can be developed without inflammatory cells infiltration and seemed not induced by CsA by itself. The major role for gingival hyperplasia by CsA would be the secondary effect of TGF-${\beta}$, which maybe upregulated by CsA administration. Low salt diet can attenuate this hyperplasia perhaps by decreasing the activation of $TGF-{\beta}$.

• Journal of the Korean Geotechnical Society
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• v.20 no.9
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• pp.77-89
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• 2004

While limit states design (LSD) is currently the standard structural design practice, it is relatively new in the geotechnical design. Adoption of LSD far geotechnical design is an international trend. In the present study, various LSD codes from the United States, Canada, and Europe were reviewed. A simple first-order-second-moment (FOSM) reliability analysis was performed to determine theoretically the ranges of load and resistance factor values for representative loads and foundation bearing capacity, respectively. In order for foundation design to be consistent with current structural design practice, it would be desirable to use the same loads, load factors and load combinations. The values of load factor, obtained from the FOSM analysis, were found to be generally consistent with those given in the codes, whereas the values of resistance factor indicated overall lower ranges due to high values of coefficient of variation used in the analysis. Since the degree of uncertainties included in bearing capacity of foundations varies with the methods used to estimate the bearing capacity, different values of resistance factor should be used fur different methods. For the purpose, continuous efforts are needed to be made first to accurately identify and quantify the uncertainties in the methods.