• 제목/요약/키워드: LS-1

검색결과 799건 처리시간 0.026초

Timing of Thoracic Radiotherapy in Limited Stage Small Cell Lung Cancer: Results of Early Versus Late Irradiation from a Single Institution in Turkey

  • Bayman, Evrim;Etiz, Durmus;Akcay, Melek;Ak, Guntulu
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권15호
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    • pp.6263-6267
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    • 2014
  • Background: It is standard treatment to combine chemotherapy (CT) and thoracic radiotherapy (TRT) in treating patients with limited stage small cell lung cancer (LS-SCLC). However, optimal timing of TRT is unclear. We here evaluated the survival impact of early versus late TRT in patients with LS-SCLC. Materials and Methods: Follow-up was retrospectively analyzed for seventy consecutive LS-SCLC patients who had successfully completed chemo-TRT between January 2006 and January 2012. Patients received TRT after either 1 to 2 cycles of CT (early TRT) or after 3 to 6 cycles of CT (late TRT). Survival and response rates were evaluated using the Kaplan-Meier method and comparisons were made using the multivariate Cox regression test. Results: Median follow-up was 24 (5 to 57) months. Carboplatin+etoposide was the most frequent induction CT (59%). Median overall, disease free, and metastasis free survivals in all patients were 15 (5 to 57), 5 (0 to 48) and 11 (3 to 57) months respectively. Late TRT was superior to early TRT group in terms of response rate (p=0.05). 3 year overall survival (OS) rates in late versus early TRT groups were 31% versus 17%, respectively (p=0.03). Early TRT (p=0.03), and incomplete response to TRT (p=0.004) were negative predictors of OS. Significant positive prognostic factors for distant metastasis free survival were late TRT (p=0.03), and use of PCI (p=0.01). Use of carboplatin versus cisplatin for induction CT had no significant impact on OS (p=0.634), DFS (p=0.727), and MFS (p=0.309). Conclusions: Late TRT appeared to be superior to early TRT in LS-SCLC treatment in terms of complete response, OS and DMFS. Carboplatin or cisplatin can be combined with etoposide in the induction CT owing to similar survival outcomes.

DVB-시스템을 위한 적응형 채널 추정 알고리즘 (Adaptive Channel Estimation Algorithm for DVB-T)

  • 김승환;이진범;이진용;김영록
    • 한국통신학회논문지
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    • 제33권6A호
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    • pp.676-684
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    • 2008
  • 유럽형 지상파 디지털 방송 표준인 DVB-T 시스템에서는 OFDM방식을 사용하여 신호를 전송하며, 주파수 선택적 페이딩 환경과 충격 잡음 채널에서도 향상된 성능을 제공 할 수 있다. 그러나 이동성이 가정된 시변 채널에서는 도플러 확산의 영향 때문에 한 OFDM 심볼 안에 존재하는 부반송파 사이의 직교성의 파괴, 즉 inter-carrier interference(ICI)가 발생하여 심각한 성능 열화가 발생한다. 본 논문에서는 시간 및 주파수 축에서 채널의 특성과 ICI를 분석하고, OFDM시스템에서 구현이 간단한 LS 알고리즘과 이를 이용한 잡음 및 ICI 감쇄 기법을 사용한 LS 방식을 단말기의 속도에 따라 선택하여 사용하는 적응형 채널 추정 방식을 제안한다. 단말기의 속도를 추정하는 방법을 제안하여 COST207의 TU6 채널 모델을 적용한 시뮬레이션을 통하여 그 동작을 확인하였다. 또한 속도 추정을 위한 연산을 최소화한 알고리즘을 제안하여 하드웨어의 증가를 무시할 정도로 줄였다. 제안된 적응형 채널 추정 알고리즘은 속도가 약 70 km/h 이하인 경우에 잡음 및 ICI 감쇄기법을 위한 하드웨어를 동작시키지 않음으로서 전력의 소모가 현저하게 줄어든다.

Estimation of co-variance components, genetic parameters, and genetic trends of reproductive traits in community-based breeding program of Bonga sheep in Ethiopia

  • Areb, Ebadu;Getachew, Tesfaye;Kirmani, MA;G.silase, Tegbaru;Haile, Aynalem
    • Animal Bioscience
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    • 제34권9호
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    • pp.1451-1459
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    • 2021
  • Objective: The objectives of the study were to evaluate reproductive performance and selection response through genetic trend of community-based breeding programs (CBBPs) of Bonga sheep. Methods: Reproduction traits data were collected between 2012 and 2018 from Bonga sheep CBBPs. Phenotypic performance was analyzed using the general linear model procedures of Statistical Analysis System. Genetic parameters were estimated by univariate animal model for age at first lambing (AFL) and repeatability models for lambing interval (LI), litter size (LS), and annual reproductive rate (ARR) traits using restricted maximum likelihood method of WOMBAT. For correlations bivariate animal model was used. Best model was chosen based on likelihood ratio test. The genetic trends were estimated by the weighted regression of the average breeding value of the animals on the year of birth/lambing. Results: The overall least squares mean±standard error of AFL, LI, LS, and ARR were 375±12.5, 284±9.9, 1.45±0.010, and 2.31±0.050, respectively. Direct heritability estimates for AFL, LI, LS, and ARR were 0.07±0.190, 0.06±0.120, 0.18±0.070, and 0.25±0.203, respectively. The low heritability for both AFL and LI showed that these traits respond little to selection programs but rather highly depend on animal management options. The annual genetic gains were -0.0281 days, -0.016 days, -0.0002 lambs and 0.0003 lambs for AFL, LI, LS, and ARR, respectively. Conclusion: Implications of the result to future improvement programs were improving management of animals, conservation of prolific flocks and out scaling the CBBP to get better results.

Effects of Pretreatment for Controlling Internal Water Transport Direction on Moisture Content Profile and Drying Defects in Large-Cross-Section Red Pine Round Timber during Kiln Drying

  • Bat-Uchral BATJARGAL;Taekyeong LEE;Myungsik CHO;Chang-Jin LEE;Hwanmyeong YEO
    • Journal of the Korean Wood Science and Technology
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    • 제51권6호
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    • pp.493-508
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    • 2023
  • Round timber materials of 600 mm length, cut from large-cross-section round timber of red pine (Pinus densiflora S. et Z.) of 450 mm width and 4.2 m length, were prepared as the target of kiln drying in this study. After treating the target materials through end sealing (ES), end sealing - kerfing (ES-K), lateral sealing - end sealing - boring (LS-ES-B), or lateral sealing - partial end sealing (LS-PES), the effects of the treatment on the incidence of drying defects were determined. The target materials with exposed lateral surface and sealed cross surface were steamed at the initial temperature of 65℃ above the official pest control temperature of 56℃, followed by kiln drying toward the final temperature of 75℃. The target materials with sealed lateral surfaces, on the other hand, were dried at the initial temperature of 90℃ at almost the maximum temperature of conventional kiln drying, as there is no risk of early check formation caused by surface moisture evaporation. The final temperature was set at approximately 100℃. The drying time, taken for the target materials with initial moisture content of 70%-80% to reach the target moisture content of 19%, varied across treatment conditions. The measured drying time was 1,146 hours (approximately 48 days) for the timber with sealed cross surface and 745 hours (approximately 31 days) for the timber with sealed lateral surface, until the moisture content reached the target level. The formation of surface checks could not be prevented in the control and ES groups, but a definite preventive effect was obtained for the LS-ES-B and LS-PES groups.

소금과 아질산염 처리수준이 자연숙성 건염햄의 지방산 조성, 유리아미노산, 미생물수 및 관능적 특성에 미치는 영향 (The Effects of Salt and NaNO2 on Fatty Acid Composition, Free Amino Acids, Microbial Counts and Sensory Characteristics of Dry-cured Ham Processed under Korean Environment)

  • 성필남;김진형;조수현;강동우;강근호;박범영;이종문;정재홍;김동훈
    • 한국축산식품학회지
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    • 제30권3호
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    • pp.435-442
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    • 2010
  • 자연환경에서 건염햄 제조 시 소금 처리 수준과 아질산염 처리 유무가 지방산 조성, 유리아미노산, 미생물수 및 관능적 특성에 어떠한 영향을 미치는 지를 조사하기 위해 HS(뒷다리 kg 당 92 g 소금 처리), HS+$NaNO_2$(뒷다리 kg 당 92 g 소금+100 ppm 아질산염 처리), LS(뒷다리 kg 당 62 g 소금 처리), LS+$NaNO_2$(뒷다리 kg 당 62 g 소금+100 ppm 아질산염 처리) 등 4개 처리구에 돼지 뒷다리 3개씩을 배치하여 조사하였다. 지방산 조성에서 SFA는 HS+$NaNO_2$ 처리구에서 다른 처리구에 비해 유의적으로 높은 비율을 나타내었고, USFA는 HS+$NaNO_2$ 처리구에서 다른 처리구에 비해 유의적으로 낮은 비율을 나타내었다(p<0.05). 유리아미노산 분석결과, 우리나라 환경에서 제조된 건염햄의 경우 glutamate(228.26-427.11 mg/100 g), alanine(356.03-579.47 mg/100 g), lysine (377.88-685.06 mg/100 g) 등이 높은 함량을 나타내었으며, proline을 제외한 모든 유리아미노산들은 소금 처리수준과 아질산염 처리 유무에 유의적인 영향을 받지 않는 것으로 조사되었다(p>0.05). 관능평가 결과, HS 처리구 보다 LS 처리구에서 유의적으로 발효취가 높은 것으로 조사되었으며(p<0.05), 총균수는 $2.3{\times}10^2-1.11{\times}10^4$ 수준이었고, E. coli, Staphylococcus aureus, E. coli O157, Salmonella spp.는 검출되지 않았다.

광독립영양세포(光獨立營養細胞)를 이용(利用)한 새로운 제초제(除草劑) 선발법(選拔法) 확립(確立) II. 담배의 녹화(綠化) 배양(培養) 세포의 Paraquat 및 Diuron 에 대한 반응(反應) (Establishment of a New Herbicides Screening Method Using Photoautotrophic Cultured Cell II. The Responses of Chlorophyllous Cells to Paraquat and Diuron in Tabacco)

  • 서수경;김길웅;권순태
    • 한국잡초학회지
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    • 제11권2호
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    • pp.137-141
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    • 1991
  • 녹화된 cal1us의 제초제 paraquat와 diuron에 대한 반응을 요약하면 다음과 같다. LS 기본(基本) 배지(培地)에 sucrose 농도(濃度) 1.0%, NAA $10^{-5}$ M, BA $10^{-6}$ M을 첨가(添加)하여 paraquat를 처리(處理) 하였을때 농도(濃度)가 $10^{-6}$ M에 서 $10^{-4}$ M으로 증가(增加) 할수록 calli의 증식(增殖)이 억제(抑制)되고 엽록소(葉綠素) 함량(含量)이 감소(減少)되었다. $10^{-4}$ M에서는 완전(完全) 고사(枯死)하였으며 $CO_2$가 공급(供給)되는 조건(條件)에서 억제(抑制) 정도가 높았다. 제초제(除草劑) diuron 처리(處理) 시(時)에도 $10^{-6}$ M에서 $10^{-3}$M으로 농도(濃度)가 증가(增加) 할수록 callus 증식(增殖)이 억제(抑制)되었으며 sucrose농도(濃度) 2.0% 때 보다 1.0%에서 훨씬 높은 억제(抑制) 경향(傾向)을 보였다.

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Auto-Measurement of Induction Motor Parameters

  • Kim Kyung-Seo;Byun Sung-Hoon
    • Journal of Electrical Engineering and Technology
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    • 제1권2호
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    • pp.226-232
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    • 2006
  • This paper presents the parameter measurement methods for high performance drive of induction motors, which are suitable for the self-commissioning function of commercial inverters. In this study, some factors that affect the accuracy of parameter measurement are examined. Measuring methods and conditions that are best fit to each parameter measurement procedure are then proposed. All the measurement procedures can be done without any auxiliary equipment, so that those can be easily adopted as self-commissioning functions of commercial inverters. To improve the measuring accuracy, least square approximation methods are adopted during the measurement procedure. The validity of the proposed methods are confirmed through experiments.

XLPE 케이블의 부분방전 신호 검출 및 위치추정 (Partial Discharge Pulse Detection and localization in XLPE Cable)

  • 이용성;김정윤;이현선;이전선;김충식
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 추계학술대회 논문집 전기설비전문위원
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    • pp.271-272
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    • 2008
  • 실선로 전력 케이블의 부분방전 측정은 주위 전력설비의 신호들이 혼합되어 검출된다. 본시험에서는 배전전력 케이블을 대상으로 부분방전 신호의 방향 추정 시험을 하였다. 시험 조건으로 모의 선로와 활선 현장선로에서 시행하였다. 2개 HFCT 센서를 사용하여 방전 펄스를 검출하였고 미소신호를 검출하기 위하여 AMP와 필터를 설계하였다. 신호 분석을 위하여 1GS/S의 스코프를 사용하였으며 자동 방향추정 S/W를 제작하였다. S/W의 특징으로는 2개의 채널에서 동일한 펄스의 시간차를 분석하여 방향을 분석하도록 하였다. 센서의 간격이 20CM일 때 약1nS의 시간차가 발생하여 신호의 방향을 추정할 수 있었다.

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접착 조인트의 전단 충격특성에 관한 연구 (A Study on the Shear Impact Characteristics of Adhesively Bonded Tubular Joints)

  • 김용하;박상근;김동옥;유용문;전성식
    • Composites Research
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    • 제25권1호
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    • pp.14-18
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    • 2012
  • 구조용 접착제는 알루미늄이나 복합재료 같은 가벼운 재질의 접합에 적용함으로써 자동차의 경량화를 이루어 연비 및 승차감등 성능향상에 큰 효과를 얻을 수 있다. 자동차와 같이 충돌환경에 노출이 되어있는 기계 구조물에 접착제를 적용하기 위해서는 접착제의 충격특성에 관한 연구가 필수적이다. 본 연구에서는 pin-ring 타입의 접착조인트를 이용하여 접착제의 전단 충격특성에 관한 연구를 수행하였으며, 충돌해석을 하기 위해 LS-DYNA를 사용하였다.

Optimized Lactic Acid Fermentation of Soybean Curd Residue (Biji)

  • Baek, Joseph;Kim, Chan-Shick;Lee, Sam-Pin
    • Preventive Nutrition and Food Science
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    • 제7권4호
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    • pp.397-404
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    • 2002
  • Soybean curd residue (SCR) was fermented by lactic acid bacteria, Lactobacillus rhamnosus LS and Entercoccus faecium LL, isolated from SCR. The pH, titratable acidify and viable cell counts were determined from the fermented SCR to evaluate the lactic acid production and growth of lactic acid bacteria. Optimal amounts of pretense enzyme and glucose, and ideal fermentation time for SCR fermentation were estimated by response surface methodology (RSM). Raw SCR fermented by indigenous microorganisms had 0.78 % titratable acidity, The acid production in SCR fermented by L. rhamnosus LS was greatly enhanced by the addition of glucose and lactose. However only glucose increased acid production by Ent. faecium LL. The proof test of SCR fermentation demonstrated that similar results for titratable acidity, tyrosine content and viable cell counts to that predicted could be obtained by the at optimized fermentation conditions. In the presence of 0.029 % (w/w) pretense enzyme and 0.9% (w/w) glucose, the SCR fermented by Ent. faecium LL showed 1.07% (w/v) of titratable acidity, 1.02 mg% tyrosine content and 2$\times$10$^{9}$ (cfu/g) of viable cell counts. With the SCR fortified with 0.033% pretense enzyme and 1.7% glucose, L. rhamnosus LS showed 1.8% (w/v) of titratable acidity, 0.92 mg% of tyrosine content and 2$\times$10$^{9}$ (cfu/g) of viable cell counts.