• Environmental Engineering Research
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• v.21 no.4
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• pp.350-354
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• 2016

There is an urgent need to identify more reliable indicator systems for human pathogenic viruses in water reuse practice. In this study, we determined the response of different bacteriophages representing various bacteriophage groups to different ultraviolet (UV) technologies in real wastewater in order to identify more reliable bacteriophage indicator systems for UV disinfection in wastewater. Bacteriophage ${\varphi}X174$ PRD1, and MS2 in two different real wastewaters were irradiated with several doses of both low pressure (LP) and medium pressure (MP) UV irradiation through bench-scale UV collimated apparatus. The inactivation rate of ${\varphi}X174$ by both LP and MP UV was rapid and reached ${\sim}4{\log}_{10}$ within a UV dose of $20mJ/cm^2$. However, the inactivation rates of bacteriophage PRD1 and MS2 were much slower than the one for ${\varphi}X174$ and only ${\sim}1{\log}_{10}$ inactivation was achieved by the same UV dose of $20mJ/cm^2$. Overall, the results of this study suggest that bacteriophage MS2 could be a reliable indicator for human pathogenic viruses for both LP and MP UV disinfection in wastewater treatment processes and water reuse practice.

• Journal of Korea Society of Industrial Information Systems
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• v.15 no.5
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• pp.187-196
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• 2010

We present a link that allows Excel to call the functions in the lp_solve system. lp_solve is free software licensed under the GPL that solves linear and mixed integer linear programs of moderate size. Our link manages the interface between Excel and lp_solve. Excel has a built-in add-in named Solver that is capable of solving mixed integer programs, but only with fewer than 200 variables. This link allows Excel users to handle substantially larger problems at no extra cost. Futhermore, we introduce that a network drawing method in Excel using arc adjacency lists of a network.

• Journal of the Korean Operations Research and Management Science Society
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• v.23 no.3
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• pp.135-151
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• 1998

The demand of large capacity in coming cellular systems makes inevitable the deployment of small cells, rendering more frequent handoff occurrences of calls than in the conventional system. The key issue is then how effectively to reduce the chance of unsuccessful handoffs, since the handoff failure is less desirable than that of a new call attempt. In this study, we consider the control policies which give priority to handoff calls by limiting channel assignment for the originating new calls, and allow queueing the new calls which are rejected at their first attempts. On this system. we propose the problem of finding an optimal call control strategy which optimizes the objective function value, while satisfying the requirements on the handoff/new call blocking probabilities and the new call delay. The objective function takes the most general form to include such well-known performance measures as the weighted average carried traffic and the handoff call blocking probability. The problem is formulated into two different linear programming (LP) models. One is based on the direct employment of steady state equations, and the other uses the theory of semi-Markov decision process. Two LP formulations are competitive each other, having its own strength in the numbers of variables and constraints. Extensive experiments are also conducted to show which call control strategy is optimal under various system environments having different objective functions and traffic patterns.

• Proceedings of the KIEE Conference
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• 1996.07b
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• pp.793-796
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• 1996

This study proposes a new algorithm which performs a production simulation under various constraints and maintains computational efficiency. In order to consider the environmental and operational constraints, the proposed algorithm is based on optimization techniques formulated in LP form In the algorithm, "system characteristic constraints" reflect the system characteristics such as LDC shape, unit loading order and forced outage rate. By using the concept of Energy Invariance Property and two operational rules i.e. Compliance Rule for Emission Constraint, Compliance Rule for Limited Energy of Individual Unit, the number of system characteristic constraints is appreciably reduced. As a solution method of the optimization problem, the author uses Karmarkar's method which performs effectively in solving large scale LP problem. The efficiency of production simulation is meaningful when it is effectively used in power system planning. With the proposed production simulation algorithm, an optimal expansion planning model which can cope with operational constraints, environmental restriction, and various uncertainties is developed. This expansion planning model is applied to the long range planning schemes by WASP, and determines an optimal expansion scheme which considers the effect of supply interruption, load forecasting errors, multistates of unit operation, plural limited energy plants etc.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.8C
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• pp.822-829
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• 2009

This paper proposes a new method of improving the quality of High Efficiency Advanced Audio Coding (HE-AAC). HE-AAC encodes input source by allocating bits for each scalefactor bands appropriately according to human ear's psychoacoustic property. As a result, insufficient bits are assigned to the bands which have relatively low energy. This imbalance between different energy bands can cause decreasing of sound quality like musical noise. In the proposed system, a Linear Prediction (LP) module is combined with HE-AAC as a pre-processor to improve sound quality by even bits distribution. To apply accurate human being's psychoacoustic property, the psychoacoustic model uses Fast Fourier Transform (FFT) spectrum of original input signal to make masking threshold. In its implementation, masking threshold of psychoacoustic model is normalized using the LP spectral envelope in prior to quantization of the LP residual. Experimental result shows that, the proposed algorithm allocates bits appropriately for insufficient bits condition and improves the performance of HE-AAC.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.38 no.4
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• pp.64-71
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• 2015

In this paper, we present a multi-period 0-1 knapsack problem which has the cardinality constraints. Theoretically, the presented problem can be regarded as an extension of the multi-period 0-1 knapsack problem. In the multi-period 0-1 knapsack problem, there are n jobs to be performed during m periods. Each job has the execution time and its completion gives profit. All the n jobs are partitioned into m periods, and the jobs belong to i-th period may be performed not later than in the i-th period, i = 1, ${\cdots}$, m. The total production time for periods from 1 to i is given by $b_i$ for each i = 1, ${\cdots}$, m, and the objective is to maximize the total profit. In the extended problem, we can select a specified number of jobs from each of periods associated with the corresponding cardinality constraints. As the extended problem is NP-hard, the branch and bound method is preferable to solve it, and therefore it is important to have efficient procedures for solving its linear programming relaxed problem. So we intensively explore the LP relaxed problem and suggest a polynomial time algorithm. We first decompose the LP relaxed problem into m subproblems associated with each cardinality constraints. Then we identify some new properties based on the parametric analysis. Finally by exploiting the special structure of the LP relaxed problem, we develop an efficient algorithm for the LP relaxed problem. The developed algorithm has a worst case computational complexity of order max[$O(n^2logn)$, $O(mn^2)$] where m is the number of periods and n is the total number of jobs. We illustrate a numerical example.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.11 no.4
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• pp.91-102
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• 1991

Traditionally, a dynamic programming(DP) technique has been used to the multireservoir control system. The algorithm has inherent problem to increase computational requirements exponentially due to discretization of variables and expanding the dimension of the system. To solve this problem, this paper describes transforming the optimal control system into a quadratic programming(QP), using Laguerre polynomials(LP) and its properties. The objective function of the proposed QP is independent of time variable. The solution of the QP is obtained by nonlinear programming(NLP) using augmented Lagrangian multiplier method. The numerical experiment shows that the water level of reservoirs is higher than Lee's and the evaluated benefit value is about the same as other researcher's.

• Archives of Pharmacal Research
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• v.27 no.6
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• pp.633-639
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• 2004

The expression of therapeutic transgenes in recombinant adenoviral vectors is a major cause of toxicity in dividing cancer cells as well as non dividing normal cells. To solve the problem of toxicity to normal cells, we have reported on a recombinant adenoviral vector system （AdLP-） in which the expression of the transgene is directed by the tumor-specific L-plastin promoter （LP） （Chung et al., 1999）. The object of this study was to generate a recombinant adenoviral vector system which would generate tumor cell specific expression of cytosine deaminase （CD） gene. We report the construction of a replication-incompetent adenoviral vector in which CD is driven by the L-plastin promoter （AdLPCD）. Infection of 293 cells by AdLPCD generated the functional CD protein as measured by HPLC analysis for the conversion of 5-Fluorocy-tosine （5-FC） to 5-Fluorouracil （5-FU）. HPLC analysis in conjunction with counting radioactivity for ［6-$^3$H］-5FC and ［6-$^3$H］-5FU demonstrated vector dose-dependent conversion of 5-FC to 5-FU in AdLPCD infected ovarian cancer cells. The results from present and previous studies（Peng et al., 2001； Akbulut et al., 2003） suggest that the use of the AdLPCD／5-FC system may be of value in the treatment of cancer including microscopic ovarian cancer in the peritoneal cavity.

• Korean Journal of Food Science and Technology
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• v.48 no.4
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• pp.378-383
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• 2016

The glasswort is an edible halophyte demonstrating various physiological effects including anti-inflammatory activity. In the present study, the effects of glasswort extracts on inflammatory events and interactions of THP-1 monocytes with intestinal epithelial cells were investigated. Five solvent fractions, including the ethylether fraction (Fr.E), were prepared from a 70% methanol extract of glasswort. THP-1 monocytes underwent differentiation by phorbol 12-myristate 13-acetate treatment and were then activated by lipopolysaccharide (LPS), which induced cyclooxygenase (COX)-2 expression. None of the glasswort fractions tested alone induced COX-2 in differentiated THP-1 cells. Fr.E, however, enhanced LPS-induced COX-2 expression in differentiated THP-1 cells. Culture media of THP-1 cells treated with each fraction stimulated the growth of normal intestinal INT-407 cells more prominently than that of HT-29 colon cancer cells. COX-2 expression in HT-29 cells was inhibited when the cells were exposed to the THP-1 culture medium treated with Fr.E. Thus, glasswort could modulate the interaction between immune cells and intestinal cells.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.4
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• pp.83-88
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• 2008

Purpose: To design an anamorphic aspherical prism lens for the HMD optical system. Methods: First, we get the initial data, needed in design, which are distances between each surface etc., by analyzing user's demended specifications and by drawing geometrically the shape of prism lens by using CAD. Based on these data and using 'ode V' which is an optical design software, we could progress the optimization in which we treat the coefficients of the anamorphic aspherical surface as the principal variables. To reduce the cost in DTM manufacturing, we would optimize the optical system with the transmitting surface, existed in the direction of video device among 3 surfaces of the prism lens, remaining as a plane. Results: we could design one anamorphic aspherical prism lens which has the finite ray aberration of 15 ${\mu}m$, the distortion of 0.5%, and the MTF value of 0.3 over at 36 lp/mm for the video device of 12 mm ${\times}$ 9 mm size. Conclusions: We designed a prism lens used for HMD. This prism lens has the optical capacities of 15 ${\mu}m$ finite ray aberration and 0.5% distortion for the video device of 12 mm ${\times}$ 9 mm size, and become the optical system having the MTF value of 0.3 over at 36 lp/mm.