• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.3
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• pp.81-89
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• 2014

This study researched on the effect of HP/LP-EGR system to improve fuel consumption of Low Temperature Combustion Engine. Firstly, low temperature combustion engine with HP/LP-EGR system was established using 6.0L wastegate turbocharger HDDI engine. And suppliable EGR rate of the engine was proven to be enough to realize stable low temperature combustion. Then, optimum operating strategy was founded to develop fuel consumption of the engine. Control parameters were HP/LP-EGR valve and IPCV(Intake Pressure Control Valve) duty. Experiments method was that characteristics of the engine were measured and analyzed according to HP/LP-EGR strategies while EGR rate was fixed. Operating range for the strategy were divided into three parts, low load for low temperature combustion, high load for conventional diesel combustion, and transient condition. Finally, with the above strategy of this study, BSFC of the engine was improved about 2% compared to the base engine, and emission level, NOx and PM, met Tier4Final emission regulation.

• Journal of Pharmaceutical Investigation
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• v.31 no.4
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• pp.217-224
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• 2001

To develop a novel transdermal delivery system of loxoprofen (LP), a potent antiinflammatory and analgesic agent, the effects of various vehicles and penetration enhancers on the skin permeation of LP from solution formulations were investigated. The permeation rate of LP through excised guinea pig skin was measured using a side-by-side permeation system at $32^{\circ}C$. The solubilities of LP in various vehicles were determined by the equilibrium solubility method, and partition coefficients $(P_c)$ were determined. The solubility of LP increased in the rank order of water & isopropyl myristate (IPM) & glyceryl dicaprylate/dicaprate & propylene glycol dicaprylate/caprate & propylene glycol laurate (PGL) & polyethylene glycol 400 & diethylene glycol monoethyl ether (DGME) & ethanol. n-Octanol-water $P_c$ value was 15.5. Among pure vehicles tested, IPM and PGL showed highest fluxes of $89.9{\pm}5.0$ and $45.4{\pm}0.3\;{\mu}g/cm^2/hr$ from saturated solutions, respectively. However, it was not possible to demonstrate any correlation between the solubility of LP and its permeation rate, indicating the change in the barrier property of the skin and/or carrier mechanisms by vehicles tested. The addition of DGME to IPM or PGL markedly increased the solubility of LP, but the permeation rate did not decrease when the concentration of DGME in the cosolvent was increased upto 40%. The addition of linoleic acid (3%) in the cosolvent slightly increased the permeation rate, but others such as lauroyl sarcosine, fatty alcohols and fatty acids tested did not show enhancing effect. In conclusion, the DGME-IPM or DGME-PGL cosolvent system proved to be a good vehicle to enhance the skin permeation of LP.

• Korean Journal of Optics and Photonics
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• v.32 no.6
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• pp.286-295
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• 2021

A modified catadioptric omnidirectional optical system (MCOOS) using an RGB/NIR CMOS sensor is optically designed for a capsule endoscope with the front field of view (FOV) in visible light (RGB) and side FOV in visible and near-infrared (NIR) light. The front image is captured by the front imaging lens system of the MCOOS, which consists of an additional three lenses arranged behind the secondary mirror of the catadioptric omnidirectional optical system (COOS) and the imaging lens system of the COOS. The side image is properly formed by the COOS. The Nyquist frequencies of the sensor in the RGB and NIR spectra are 90 lp/mm and 180 lp/mm, respectively. The overall length of 12 mm, F-number of 3.5, and two half-angles of front and side half FOV of 70° and 50°-120° of the MCOOS are determined by the design specifications. As a result, a spatial frequency of 154 lp/mm at a modulation transfer function (MTF) of 0.3, a depth of focus (DOF) of -0.051-+0.052 mm, and a cumulative probability of tolerance (CPT) of 99% are obtained from the COOS. Also, the spatial frequency at MTF of 170 lp/mm, DOF of -0.035-0.051 mm, and CPT of 99.9% are attained from the front-imaging lens system of the optimized MCOOS.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.05a
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• pp.404-406
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• 2016

Due to the localization process of offshore drilling system, ensuring safety has emerged as an important. Therefore, step by stem safety analysis about each development process of offshore drilling system is becoming compulsory. Hazard and operability analysis is a method that was successfully used for system safety analysis in industries such as chemical plants. Through this hazard and operability analysis study, to conduct step by step safety analysis accorsing to process, the study conducted hazard and operability analysis in Lp mud system, an area of offshore drilling system.

• Journal of Gynecologic Oncology
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• v.29 no.6
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• pp.87.1-87.4
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• 2018

Objective: Upper paraaortic lymph node dissection (UPALD) to the infrarenal level is one of the most challenging robotic procedures. Because robotic system has the limitation in robotic arm mobility. This surgical video introduces a novel robotic approach, lower pelvic port placement (LP3), to perform optimally and simultaneously both UPALD and pelvic procedures in gynecologic cancer patients using da Vinci Xi system. Methods: The patient presented with high-grade endometrial cancer. She underwent robotic surgical staging operation. For the setup of the LP3, a line was drown between both anterior superior iliac spines. At 3 cm below this line, another line was drown and four robotic ports were placed on this line. Results: After paraaortic lymph node dissection (PALD) was completed, the boom of robotic system was rotated $180^{\circ}$ to retarget for the pelvic lateral displacement. Robotic ports were placed and docked again. The operation was completed robotically without any complication. Conclusion: The LP3 was feasible for performing simultaneously optimal PALD as well as procedures in pelvic cavity in gynecologic cancer patients. The advantage of LP3 technique is the robotic port placement that affords for multi-quadrant surgery, abdominal and pelvic dissection. The LP3 is facilitated by utilizing advanced technology of Xi system, including the patient clearance function, the rotating boom, and 'port hopping' that allows using every ports for a camera. The LP3 will enable surgeons to extend the surgical indication of robotic surgical system in the gynecologic oncologic field.

• 한국가스학회:학술대회논문집
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• 2000.09a
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• pp.130-136
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• 2000

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.10
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• pp.909-919
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• 2014

License plate (LP) detection is the most imperative part of an automatic LP recognition (LPR) system. Typical LPR contains two steps, namely LP detection (LPD) and character recognition. In this paper, we propose an efficient Vehicle-to-LP detection framework which combines with an adaptive GMM (Gaussian Mixture Model) and a cascade of boosted classifiers to make a faster vehicle LP detector. To develop a background model by using a GMM is possible in the circumstance of a fixed camera and extracts the motions using background subtraction. Firstly, an adaptive GMM is used to find the region of interest (ROI) on which motion detectors are running to detect the vehicle area as blobs ROIs. Secondly, a cascade of boosted classifiers is executed on the blobs ROIs to detect a LP. The experimental results on our test video with the resolution of $720{\times}576$ show that the LPD rate of the proposed system is 99.14% and the average computational time is approximately 42ms.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.20 no.3
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• pp.273-282
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• 2002

Although the influence of GIS has been proved in a variety of applications, there also have been some research issues about that the coupling of GIS with other mathematical or engineering tools is necessary to meet various needs of specialized problem domains. Linear Programming, a mathematical technique used in optimal distribution of given quantity, can enhance its usability by integrating with GIS since LP basically does not include means to deal with spatial data. The limitation of the traditional LP technique is that it requires explicitly defined conditions, which is impractical or impossible in such decision making processes as in land use problems that use less crisp decision factors. This study develops a method to incorporate such fuzzy situations by integrating Fuzzy-LP that employs fuzzy logic and GIS. The GIS provides data to or displays data from the Fuzzy-LP processes in the integrated system. This methodology is illustrated to solve a land use distribution problem.

• Journal of Advanced Marine Engineering and Technology
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• v.35 no.4
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• pp.379-387
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• 2011

Research and development of LP EGR system for the performance improvement and emission reduction on diesel engine is proceeding at a good pace. LP EGR system seems to be helpful method to further reduce$NO_x$ emissions while maintaining PM emissions at a low level because the boost pressure is unchanged while varying EGR rate. This study is experimentally conducted on a 2.0L common rail DI engine at the medium load condition (2000 rpm, BMEP 1.0 MPa, boost pressure 181.3 kPa) that difficult to use large amount of EGR gas because of deteriorations of performance and fuel consumption. And we investigated the characteristics of performance and fuel consumption while varying EGR systems. The overall results using LP EGR system equipped with ETC identified benefits on reduction of PM and improvement of fuel consumption and thermal efficiency while keep the $NO_x$ level compared to HP EGR and LP EGR with back pressure valve.

• Bulletin of the Korean Chemical Society
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• v.27 no.9
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• pp.1335-1340
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• 2006

It has been found that a number of diseases are associated with mutations in the mitochondrial DNA. Therapeutic gene delivery to mitochondria has been suggested as a clinical option for these diseases. In this study, we developed a gene carrier to mitochondria by the conjugation of mitochondrial leader peptide (LP) to polyethylenimine (PEI). Mitochondrial LP conjugated PEI (PEI-LP) was synthesized with low molecular weight PEI (2,000 Da, PEI2K). Gel retardation assay showed that PEI2K-LP formed complexes at a 1.0/1 weight ratio. In addition, PEI2K-LP protected DNA from the enzymatic degradation for at least 60 min, while naked DNA was completely degraded within 20 min. PEI2K-LP was compared with LP conjugated high molecular weight PEI (25,000 Da, PEI25K) in terms of toxicity and delivery efficiency. MTT assay showed that PEI2K-LP had much lower cytotoxicity than PEI25K-LP to 293 cells. In addition, cell-free DNA delivery assay showed that PEI2K-LP delivered more DNA to mitochondria at a 1.8/1 weight ratio than naked DNA or PEI. This result suggests that PEI2K-LP may be useful for the development of mitochondrial gene therapy system with lower cytotoxicity.